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The map label for this gene is exoB [H]

Identifier: 86748137

GI number: 86748137

Start: 1160679

End: 1161662

Strand: Reverse

Name: exoB [H]

Synonym: RPB_1012

Alternate gene names: 86748137

Gene position: 1161662-1160679 (Counterclockwise)

Preceding gene: 86748138

Following gene: 86748136

Centisome position: 21.79

GC content: 68.09

Gene sequence:

>984_bases
ATGGACAACTACATCCTCGTCACCGGCGGCGCCGGCTATATCGGCAGCCATATGACGCTGGCGTTGCAGGCGGCCGGCGA
ACGGCCGCTGGTGATCGACGATCTCTCCGCTGGGCTGCGCCGCGCCGTTCCGGAGGGCGTACCGCTGTTCGAGGGCTCGG
TCGGCGATTCCGATTTCGTCGGCGACATCATGGATCGCCATCCGATCGCGGCGATCATCCATTTCGCGGCCAGCGTGGTG
GTGCCGGAATCGGTCGCGCAGCCGCTGGCCTATTATCGCAACAACACCGCCAACGCCCGCACGCTGATCGACTGCGCGGT
GCAGCGGCGGATTCCGCATGTCGTGTTCTCGTCGACCGCGGCTGTGTATGGCGAGCCCGATCGCAATCCGATCGGCGAAG
ACCAGCCGACGCAGCCGATCAATCCCTATGGCCGCTCGAAACTGATGGTCGAATGGATGCTCGGCGACGTCGCCCGCGCG
CATCCGCTGAGCTACGCGGCGCTGCGCTACTTCAACGTCGCCGGCGCCGATCCGGACGGCCGCGCCGGGCAGTCGTCGCC
GAACGCCACGCATCTGATCAAGATCGCCGTGCAGGCCGCGCTCGGCAAGCGCGACGGGCTCGACGTGTTCGGCACCGACT
ATCCGACCGCGGACGGCTCCTGCATCCGCGACTACGTCCATGTCGCCGATCTCGTCGCCGCGCATCTCGACGCGCTGCGC
TATCTGCGCGCCGGCCATCCCAGCGTCACCTGCAACATCGGCTATGCCAGCGGCTATTCGGTGCTGCAGGTGATCGAGGT
GGTCAAGCGCGTCTCCGGCGTCGATTTTCCGGTGCGCCTCCAAGGCCGCCGCGCCGGCGATCCCGCCGCGCTGGTGGCTG
CGAACGAACGCGCGAAGACGCTGCTGGGCTGGACGCCGCGCTACGACGATCTCGAGACCATCGTGCGCCACGCGCTGGCC
TGGGAACGCCGGCTCGGCGCCTGA

Upstream 100 bases:

>100_bases
ACCTGGGGCGTGGCAATTGCGAGCAGTCGCCTCCGGTTGCAGAGCCACGCCGGGCCCTGAGCGTCCGACGGGCCGCCGCC
CACAGCCACGGAAGACCGAT

Downstream 100 bases:

>100_bases
GCCCGCGCTCGCGCCGCTGCGTCATCCCGGAACCCCGGGCCATGCCGGCACAGAGCTGTCACAGCGCGGCACATCCGGGC
GAAAACATCGGCCGATTTCG

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MDNYILVTGGAGYIGSHMTLALQAAGERPLVIDDLSAGLRRAVPEGVPLFEGSVGDSDFVGDIMDRHPIAAIIHFAASVV
VPESVAQPLAYYRNNTANARTLIDCAVQRRIPHVVFSSTAAVYGEPDRNPIGEDQPTQPINPYGRSKLMVEWMLGDVARA
HPLSYAALRYFNVAGADPDGRAGQSSPNATHLIKIAVQAALGKRDGLDVFGTDYPTADGSCIRDYVHVADLVAAHLDALR
YLRAGHPSVTCNIGYASGYSVLQVIEVVKRVSGVDFPVRLQGRRAGDPAALVAANERAKTLLGWTPRYDDLETIVRHALA
WERRLGA

Sequences:

>Translated_327_residues
MDNYILVTGGAGYIGSHMTLALQAAGERPLVIDDLSAGLRRAVPEGVPLFEGSVGDSDFVGDIMDRHPIAAIIHFAASVV
VPESVAQPLAYYRNNTANARTLIDCAVQRRIPHVVFSSTAAVYGEPDRNPIGEDQPTQPINPYGRSKLMVEWMLGDVARA
HPLSYAALRYFNVAGADPDGRAGQSSPNATHLIKIAVQAALGKRDGLDVFGTDYPTADGSCIRDYVHVADLVAAHLDALR
YLRAGHPSVTCNIGYASGYSVLQVIEVVKRVSGVDFPVRLQGRRAGDPAALVAANERAKTLLGWTPRYDDLETIVRHALA
WERRLGA
>Mature_327_residues
MDNYILVTGGAGYIGSHMTLALQAAGERPLVIDDLSAGLRRAVPEGVPLFEGSVGDSDFVGDIMDRHPIAAIIHFAASVV
VPESVAQPLAYYRNNTANARTLIDCAVQRRIPHVVFSSTAAVYGEPDRNPIGEDQPTQPINPYGRSKLMVEWMLGDVARA
HPLSYAALRYFNVAGADPDGRAGQSSPNATHLIKIAVQAALGKRDGLDVFGTDYPTADGSCIRDYVHVADLVAAHLDALR
YLRAGHPSVTCNIGYASGYSVLQVIEVVKRVSGVDFPVRLQGRRAGDPAALVAANERAKTLLGWTPRYDDLETIVRHALA
WERRLGA

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=342, Percent_Identity=38.0116959064327, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI56118217, Length=342, Percent_Identity=38.0116959064327, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI189083684, Length=342, Percent_Identity=38.0116959064327, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI42516563, Length=307, Percent_Identity=25.7328990228013, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI7657641, Length=335, Percent_Identity=24.7761194029851, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1786974, Length=335, Percent_Identity=38.8059701492537, Blast_Score=197, Evalue=6e-52,
Organism=Escherichia coli, GI1790049, Length=334, Percent_Identity=26.0479041916168, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71982035, Length=340, Percent_Identity=36.1764705882353, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI71982038, Length=342, Percent_Identity=35.672514619883, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17539532, Length=314, Percent_Identity=24.203821656051, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319493, Length=320, Percent_Identity=38.75, Blast_Score=205, Evalue=9e-54,
Organism=Drosophila melanogaster, GI19923002, Length=321, Percent_Identity=36.4485981308411, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI21356223, Length=324, Percent_Identity=24.6913580246914, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35190; Mature: 35190

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNYILVTGGAGYIGSHMTLALQAAGERPLVIDDLSAGLRRAVPEGVPLFEGSVGDSDFV
CCCEEEEECCCCCCCCCEEEEEEECCCCCEEEHHHHHHHHHHCCCCCCEECCCCCCCHHH
GDIMDRHPIAAIIHFAASVVVPESVAQPLAYYRNNTANARTLIDCAVQRRIPHVVFSSTA
HHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEECCCE
AVYGEPDRNPIGEDQPTQPINPYGRSKLMVEWMLGDVARAHPLSYAALRYFNVAGADPDG
EEECCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCC
RAGQSSPNATHLIKIAVQAALGKRDGLDVFGTDYPTADGSCIRDYVHVADLVAAHLDALR
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
YLRAGHPSVTCNIGYASGYSVLQVIEVVKRVSGVDFPVRLQGRRAGDPAALVAANERAKT
HHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEECCCHHHH
LLGWTPRYDDLETIVRHALAWERRLGA
HCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDNYILVTGGAGYIGSHMTLALQAAGERPLVIDDLSAGLRRAVPEGVPLFEGSVGDSDFV
CCCEEEEECCCCCCCCCEEEEEEECCCCCEEEHHHHHHHHHHCCCCCCEECCCCCCCHHH
GDIMDRHPIAAIIHFAASVVVPESVAQPLAYYRNNTANARTLIDCAVQRRIPHVVFSSTA
HHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEECCCE
AVYGEPDRNPIGEDQPTQPINPYGRSKLMVEWMLGDVARAHPLSYAALRYFNVAGADPDG
EEECCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCC
RAGQSSPNATHLIKIAVQAALGKRDGLDVFGTDYPTADGSCIRDYVHVADLVAAHLDALR
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
YLRAGHPSVTCNIGYASGYSVLQVIEVVKRVSGVDFPVRLQGRRAGDPAALVAANERAKT
HHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEECCCHHHH
LLGWTPRYDDLETIVRHALAWERRLGA
HCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]