Click here to switch to the map view.

The map label for this gene is tagA [H]

Identifier: 86748136

GI number: 86748136

Start: 1159529

End: 1160440

Strand: Reverse

Name: tagA [H]

Synonym: RPB_1011

Alternate gene names: 86748136

Gene position: 1160440-1159529 (Counterclockwise)

Preceding gene: 86748137

Following gene: 86748132

Centisome position: 21.77

GC content: 68.53

Gene sequence:

>912_bases
ATGTCCGACGTCAGCGGCCGACTGCCGACCCCCGCGCCCGGCCGACCTCGGGAGTCCGATCGCCGCGTCGCGCCGTTCGC
GATCCCCGCCTCGATCGCCGCTCTGCCGTTCGACGAGCGTCGCGTCACCGGCGAACGCCGGCGCGATCGATTTTCGCAGT
GGAAGCGCAACATCATCGGCGGCCTGCCGATCGTGGTCGCCGATCGCGCCGAGACCGCGACCGCGATGGTCGACGAGGCG
CTGAAGCGTCGCGGCCTGTGGCGCTATCCCGCCTACATGACGTCGACCAACGGCGAAGTGACCTATCGCTGCGCGGTCGA
TCCGTCCGAGCACGCGATGTTTCTGCAGGCCGATGCGATTCATGCCGACGGCATGCCGCACGTCTTCGTCTCGCGCTTCA
AATGCGACGTGCCGCTGCCGGAGCGCGTCGCCACCACCGACCTGTTCCACGATGTCGCGCGCGAGGCCGGCGCACGCGGC
GCGACGATGTTCATGCTCGGCGCCGACGAGACCTCGAACCAGCGCGCGGCGGAGTGGGTCGCAACCAACTATCCCGAGGT
CCGGCTGGTCGGCCGCCGCAACGGCTACTTCGCCGACGACGCCGAAGAGATCGCCGCCTGCCGGCAGATCGCCGAACTTG
CCCCCGACATTCTCTGGATCTCGATGGGGGTGCCGCGCGAGCAATTGTTCATCGGCCGGCATCGCCATCGCCTGACCACC
GTGGGTGTCATCAAGACGTCCGGCGGGCTGTTCGATTTCCTGTCCGGATCGAAGCCGCGGGCGCCGCTGTGGATGCAGCG
CGTCGGCCTGGAATGGCTGTGGCGGATGGCGCTGGAGCCGCGCCGGCTCGGGATGCGCTATCTCAGGACCAACCCTTACG
CGATGTATCTGCTGCTGACGCGAACGCGGTGA

Upstream 100 bases:

>100_bases
CGGTTAAGCAGCGATTGCATGGTCGTTAAGATGAGCTAATTGTTCTCGTCGAAATGATCGAACCGCCGTCTCGAAACGGC
GGCAAGCAGCGGAATTCGCA

Downstream 100 bases:

>100_bases
TCCGGTTCATTGATCGATTTCGTCATGGCCGGGCTCGTCCCGGCCATCCACGTCTTCGGACCCAGCCCCCTGGAAAGACG
TGGATACCCGGCGCAAGGTC

Product: WecB/TagA/CpsF family glycosyl transferase

Products: NA

Alternate protein names: Major teichoic acid biosynthesis protein A; N-acetylglucosaminyldiphospho-undecaprenol N-acetyl-beta-D-mannosaminyltransferase; UDP-N-acetylmannosamine transferase [H]

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSDVSGRLPTPAPGRPRESDRRVAPFAIPASIAALPFDERRVTGERRRDRFSQWKRNIIGGLPIVVADRAETATAMVDEA
LKRRGLWRYPAYMTSTNGEVTYRCAVDPSEHAMFLQADAIHADGMPHVFVSRFKCDVPLPERVATTDLFHDVAREAGARG
ATMFMLGADETSNQRAAEWVATNYPEVRLVGRRNGYFADDAEEIAACRQIAELAPDILWISMGVPREQLFIGRHRHRLTT
VGVIKTSGGLFDFLSGSKPRAPLWMQRVGLEWLWRMALEPRRLGMRYLRTNPYAMYLLLTRTR

Sequences:

>Translated_303_residues
MSDVSGRLPTPAPGRPRESDRRVAPFAIPASIAALPFDERRVTGERRRDRFSQWKRNIIGGLPIVVADRAETATAMVDEA
LKRRGLWRYPAYMTSTNGEVTYRCAVDPSEHAMFLQADAIHADGMPHVFVSRFKCDVPLPERVATTDLFHDVAREAGARG
ATMFMLGADETSNQRAAEWVATNYPEVRLVGRRNGYFADDAEEIAACRQIAELAPDILWISMGVPREQLFIGRHRHRLTT
VGVIKTSGGLFDFLSGSKPRAPLWMQRVGLEWLWRMALEPRRLGMRYLRTNPYAMYLLLTRTR
>Mature_302_residues
SDVSGRLPTPAPGRPRESDRRVAPFAIPASIAALPFDERRVTGERRRDRFSQWKRNIIGGLPIVVADRAETATAMVDEAL
KRRGLWRYPAYMTSTNGEVTYRCAVDPSEHAMFLQADAIHADGMPHVFVSRFKCDVPLPERVATTDLFHDVAREAGARGA
TMFMLGADETSNQRAAEWVATNYPEVRLVGRRNGYFADDAEEIAACRQIAELAPDILWISMGVPREQLFIGRHRHRLTTV
GVIKTSGGLFDFLSGSKPRAPLWMQRVGLEWLWRMALEPRRLGMRYLRTNPYAMYLLLTRTR

Specific function: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, a key lipid intermediate in the de novo synthesis of teichoic acid (Potential) [H]

COG id: COG1922

COG function: function code M; Teichoic acid biosynthesis proteins

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 26 family [H]

Homologues:

Organism=Escherichia coli, GI2367289, Length=168, Percent_Identity=29.7619047619048, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004629 [H]

Pfam domain/function: PF03808 Glyco_tran_WecB [H]

EC number: =2.4.1.187 [H]

Molecular weight: Translated: 34316; Mature: 34185

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVSGRLPTPAPGRPRESDRRVAPFAIPASIAALPFDERRVTGERRRDRFSQWKRNIIG
CCCCCCCCCCCCCCCCCCCCCCCCCEECCCHHHCCCCHHHHCCHHHHHHHHHHHHHHHHC
GLPIVVADRAETATAMVDEALKRRGLWRYPAYMTSTNGEVTYRCAVDPSEHAMFLQADAI
CCCEEEECCCHHHHHHHHHHHHHCCCEECCCEEECCCCCEEEEEECCCCCCEEEEEECCC
HADGMPHVFVSRFKCDVPLPERVATTDLFHDVAREAGARGATMFMLGADETSNQRAAEWV
CCCCCCHHHHHHEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHH
ATNYPEVRLVGRRNGYFADDAEEIAACRQIAELAPDILWISMGVPREQLFIGRHRHRLTT
HCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCEEEE
VGVIKTSGGLFDFLSGSKPRAPLWMQRVGLEWLWRMALEPRRLGMRYLRTNPYAMYLLLT
EEEEECCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCHHHHCCCCEEEEEEEE
RTR
ECC
>Mature Secondary Structure 
SDVSGRLPTPAPGRPRESDRRVAPFAIPASIAALPFDERRVTGERRRDRFSQWKRNIIG
CCCCCCCCCCCCCCCCCCCCCCCCEECCCHHHCCCCHHHHCCHHHHHHHHHHHHHHHHC
GLPIVVADRAETATAMVDEALKRRGLWRYPAYMTSTNGEVTYRCAVDPSEHAMFLQADAI
CCCEEEECCCHHHHHHHHHHHHHCCCEECCCEEECCCCCEEEEEECCCCCCEEEEEECCC
HADGMPHVFVSRFKCDVPLPERVATTDLFHDVAREAGARGATMFMLGADETSNQRAAEWV
CCCCCCHHHHHHEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHH
ATNYPEVRLVGRRNGYFADDAEEIAACRQIAELAPDILWISMGVPREQLFIGRHRHRLTT
HCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCEEEE
VGVIKTSGGLFDFLSGSKPRAPLWMQRVGLEWLWRMALEPRRLGMRYLRTNPYAMYLLLT
EEEEECCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCHHHHCCCCEEEEEEEE
RTR
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1906926; 9384377; 11882717 [H]