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The map label for this gene is arcA [H]

Identifier: 86747968

GI number: 86747968

Start: 957753

End: 958739

Strand: Reverse

Name: arcA [H]

Synonym: RPB_0842

Alternate gene names: 86747968

Gene position: 958739-957753 (Counterclockwise)

Preceding gene: 86747969

Following gene: 86747967

Centisome position: 17.98

GC content: 70.52

Gene sequence:

>987_bases
ATGACGCCCTCCAGCTCCGTGATCCCGCCCGATCCGAACCGCCGCGTCGCGCTGCTCGGGGTGCCGATCGAGATCGGCGC
CGGGCTGCGCGGCACGCTGATGGGCCCGGCGGCGCTGCGCACCGCGGGTATCGGCCGCGTGCTCGAACAGTTGCGCATCA
CCGTCGAGGATCACGGCGACATGGCGCGGCCGCCACCTTGTCGCGACGCGGGTCCGACGCCGGCCAACGCCAATTATTAC
GACGAGGTGAAAAGCTGGGTCGGCGCGATCTCGGCGCGGGCCCATGAGCTGGCGCGTTCCGGCGCCGTGCCGCTGTTCAT
GGGCGGCGATCACAGCCTGTCGATGGGCTCGGTCAACGGCGTCGCGCGCTATTGGCAGACGCAGGGGCGGCCGCTGTTCG
TGCTGTGGTTCGACGCCCACGCCGACTACAACACCCCGGCGACGACGCTCTCCGCCAACATGCACGGCATGTCGGCGGCG
TTCCTGTGCGGCGAGCCGGGGCTCGATGCGCTGCTCGGCGACGAGCCCCGGGTGTCGATCCCGCCCGACCGGCTCGACCT
GTTCGGCATCCGATCGATCGATCCGCTGGAGAAGGAATTGGTGCGCGCCCGCGCCATCCCGGTGGTCGACATGCGGGCGA
TCGACGAATTCGGCGTCGGCGTGCTGATCCGCCGGTTGATCGACCGCGTCCGCGCGGCGAACGGCGTGCTGCATCTGTCG
TTCGATGTCGACGTGCTCGACCCTGCGGTCGCGCCCGGCGTCGGCACCACCGTGCCGGGCGGCGCGACCTATCGGGAGGC
GCATCTGGTGATGGAGCTGCTGCACGACTCGGGATTGGTGCGTTCGCTCGACGTGGTCGAACTCAACCCCTTCCTCGACG
AGCGCGGCCGCACCGCCCGGGTCGCGGTGGAGCTGATCGGCAGCCTGTTCGGCATGCAGATCTCCGACCGGGTGACGCCG
AGCAACGCGCTGCTGCCCGAGGGGTGA

Upstream 100 bases:

>100_bases
GGCCTGATCCAGCCGCGCCGCCATCGCGTTGTCGTCACGCGAAGCGGCTATGGCCTGCGCGTGACAACGCTCCGGCCCAC
TTGCCCGAAAGGCGCCGCGC

Downstream 100 bases:

>100_bases
GCGCCATCCCCGCGGTCGTCATTCCGGGGGGAGCGCTCTCCCCGCGCTCGTCATTCCGGGGCGCTCGCCCTTGCGAGCGA
ACCCGGAATCTCGCAGTTTT

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MTPSSSVIPPDPNRRVALLGVPIEIGAGLRGTLMGPAALRTAGIGRVLEQLRITVEDHGDMARPPPCRDAGPTPANANYY
DEVKSWVGAISARAHELARSGAVPLFMGGDHSLSMGSVNGVARYWQTQGRPLFVLWFDAHADYNTPATTLSANMHGMSAA
FLCGEPGLDALLGDEPRVSIPPDRLDLFGIRSIDPLEKELVRARAIPVVDMRAIDEFGVGVLIRRLIDRVRAANGVLHLS
FDVDVLDPAVAPGVGTTVPGGATYREAHLVMELLHDSGLVRSLDVVELNPFLDERGRTARVAVELIGSLFGMQISDRVTP
SNALLPEG

Sequences:

>Translated_328_residues
MTPSSSVIPPDPNRRVALLGVPIEIGAGLRGTLMGPAALRTAGIGRVLEQLRITVEDHGDMARPPPCRDAGPTPANANYY
DEVKSWVGAISARAHELARSGAVPLFMGGDHSLSMGSVNGVARYWQTQGRPLFVLWFDAHADYNTPATTLSANMHGMSAA
FLCGEPGLDALLGDEPRVSIPPDRLDLFGIRSIDPLEKELVRARAIPVVDMRAIDEFGVGVLIRRLIDRVRAANGVLHLS
FDVDVLDPAVAPGVGTTVPGGATYREAHLVMELLHDSGLVRSLDVVELNPFLDERGRTARVAVELIGSLFGMQISDRVTP
SNALLPEG
>Mature_327_residues
TPSSSVIPPDPNRRVALLGVPIEIGAGLRGTLMGPAALRTAGIGRVLEQLRITVEDHGDMARPPPCRDAGPTPANANYYD
EVKSWVGAISARAHELARSGAVPLFMGGDHSLSMGSVNGVARYWQTQGRPLFVLWFDAHADYNTPATTLSANMHGMSAAF
LCGEPGLDALLGDEPRVSIPPDRLDLFGIRSIDPLEKELVRARAIPVVDMRAIDEFGVGVLIRRLIDRVRAANGVLHLSF
DVDVLDPAVAPGVGTTVPGGATYREAHLVMELLHDSGLVRSLDVVELNPFLDERGRTARVAVELIGSLFGMQISDRVTPS
NALLPEG

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI4502215, Length=314, Percent_Identity=35.3503184713376, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI10947139, Length=330, Percent_Identity=33.6363636363636, Blast_Score=162, Evalue=3e-40,
Organism=Escherichia coli, GI1789306, Length=287, Percent_Identity=26.1324041811847, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71996843, Length=218, Percent_Identity=30.2752293577982, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6325146, Length=305, Percent_Identity=29.5081967213115, Blast_Score=122, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24638886, Length=329, Percent_Identity=31.0030395136778, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 35067; Mature: 34935

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSSSVIPPDPNRRVALLGVPIEIGAGLRGTLMGPAALRTAGIGRVLEQLRITVEDHGD
CCCCCCCCCCCCCCEEEEEECCCEECCCCCCEECCHHHHHHHHHHHHHHHHEEEEECCCC
MARPPPCRDAGPTPANANYYDEVKSWVGAISARAHELARSGAVPLFMGGDHSLSMGSVNG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHH
VARYWQTQGRPLFVLWFDAHADYNTPATTLSANMHGMSAAFLCGEPGLDALLGDEPRVSI
HHHHHHCCCCEEEEEEEECCCCCCCCCCEEECCCCCCEEEEEECCCCCHHHCCCCCCCCC
PPDRLDLFGIRSIDPLEKELVRARAIPVVDMRAIDEFGVGVLIRRLIDRVRAANGVLHLS
CCCCEEEEECCCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
FDVDVLDPAVAPGVGTTVPGGATYREAHLVMELLHDSGLVRSLDVVELNPFLDERGRTAR
ECCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECHHHHCCCCHHH
VAVELIGSLFGMQISDRVTPSNALLPEG
HHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TPSSSVIPPDPNRRVALLGVPIEIGAGLRGTLMGPAALRTAGIGRVLEQLRITVEDHGD
CCCCCCCCCCCCCEEEEEECCCEECCCCCCEECCHHHHHHHHHHHHHHHHEEEEECCCC
MARPPPCRDAGPTPANANYYDEVKSWVGAISARAHELARSGAVPLFMGGDHSLSMGSVNG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHH
VARYWQTQGRPLFVLWFDAHADYNTPATTLSANMHGMSAAFLCGEPGLDALLGDEPRVSI
HHHHHHCCCCEEEEEEEECCCCCCCCCCEEECCCCCCEEEEEECCCCCHHHCCCCCCCCC
PPDRLDLFGIRSIDPLEKELVRARAIPVVDMRAIDEFGVGVLIRRLIDRVRAANGVLHLS
CCCCEEEEECCCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
FDVDVLDPAVAPGVGTTVPGGATYREAHLVMELLHDSGLVRSLDVVELNPFLDERGRTAR
ECCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECHHHHCCCCHHH
VAVELIGSLFGMQISDRVTPSNALLPEG
HHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2806247; 3040404; 11743193; 11743194 [H]