Click here to switch to the map view.

The map label for this gene is 86747830

Identifier: 86747830

GI number: 86747830

Start: 790115

End: 791536

Strand: Reverse

Name: 86747830

Synonym: RPB_0704

Alternate gene names: NA

Gene position: 791536-790115 (Counterclockwise)

Preceding gene: 86747831

Following gene: 86747829

Centisome position: 14.85

GC content: 66.95

Gene sequence:

>1422_bases
ATGCCGCAAGCGACCGTCGATCGCGCGTCGGAGTTTCTCGGCGGCCTGTTCACGAGCCTCACCGAACGTGGCCGCAGCCT
GTTCAAGTCGAGCAGCGACCAGCCGAAGAGCAAGGACGAACTGATCGCGCTCGGCGAGGCGCTGCTGTCACGCCGCGGCG
AGGCCACCGGCGTGGCGATGGCGCATCAATTGTTGTCCGGCTATGACGGCGCCGCCGAGGACGATCAGCTCGGCTTCCTC
GACGCGCTGGCCGAACAATTCGGCCCCGATCTCGCCGAACTCACGGCGGCCGTCGAAAACTTCCATGTCAGCGGCGCATC
GCCGGACGCCGCCTCGCAACTCCTCAAGGCCGCCGAGCCGCGCCGGCAGGAGCTGATCCGCCGGCTCAACCTCGCGCCGG
GCGGCACCGCGTCGCTGGTGCGGATGCGCGAGGCGGTGCTGACGCATCTGCGCGACCACCCGCAACTCAGGAACGTCGAC
GACGATTTCGTGCATCTGTTCACCTCCTGGTTCAATCGGGGCTTTCTGGTGCTGCAACGAATCGACTGGACTACGCCGGC
CAACATTCTCGAGAAGATCATTCGCTACGAGCAGGTCCACGCCATCCGCAATTGGGACGATCTGCGCGCACGACTCGCGC
CGGCGGACCGGCGCTGCTACGGCTTCTTCCATCCGCAGCTCGTCGACGAGCCGCTGATTTTCGTCGAGGTGGCGCTGACG
CTGGATCGCCCGGGTGCGATCGCGCCGCTGCTCGATCTGGAGCGGGCGCCGATCTCGCCCAAGGATGCGACCACGGCGGT
GTTCTACTCGATCTCCAATACCCAGAAGGGCCTCGCCGGCATCTCGTTCGGCAATTTCCTGATCAAGCAGGTGGTCGAGG
AGATCAAGCGCGAGCTGCCCAACGTGCAGAGCTTCGTCACGCTGTCGCCGGTGCCGGGCTTCGCGAAATGGCTGAAGCAG
GAGCGCGCCGACGAGGCGTCGGCGTTGCTCGACGACTCCGCCCGTGCCGAACTCGCGGTGCTGGACGCGCCGGATTGGCA
GGACGATCCCGAACGCGCCGATCACATCAAGCCTTTGCTGCTGCCGCTGGCGGCCGCGTACTTCCTGCAGGCCAAGAATG
CCCGCGGCCTGCCGCTCGACCCGGTAGCGCGCTTCCATCTCGGCAACGGCGCGCGGCTGGAGAGCCTCAATTTCCTCGGC
GACCGCTCGCCCAACGGGATGCGGCAATCGCACGGACTGATGGTGAACTATCTGTATGCGCTCGGCGAGATCGAGGCCAA
CCACGAGGCCTTCGCCGAACGCGCCCAGATCGCGGCCGCCTCCGCGGTCCGTAAGCAACTGCCGTCCAAGCCGCTGAGCA
GCGAGCCGCGCAAGACCAACGGCAAGACCTCCGCCCCGCTGGCGATCGCACCGCCGGCGTGA

Upstream 100 bases:

>100_bases
GCGTGAAGCGTCTAGAAGCCGTCGGCTGGAATCTCTATGATTTCGGGTGAGACTGCGTCTTGTTCGCGACACGTCCAATC
GAAGCCAGGGGAGAAACGGC

Downstream 100 bases:

>100_bases
CGCACCCTCGGCTCGAGCAATGCCCTAACCCCGTCATTGCGAGCGGAGCGAAGCAATCCAGACACCGTGCACCGAGCTTC
TGGATTGCTTCGTCGCTACG

Product: malonyl-CoA decarboxylase

Products: acetyl-CoA; CO2

Alternate protein names: Malonyl-CoA Decarboxylase Superfamily; Malonyl-CoA Decarboxylase Superfamily Protein; Malonyl-CoA Decarboxylase Protein; MCD Malonyl-CoA Decarboxylase MCD; Malonyl-CoA Decarboxylase Family Protein; Decarboxylase

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MPQATVDRASEFLGGLFTSLTERGRSLFKSSSDQPKSKDELIALGEALLSRRGEATGVAMAHQLLSGYDGAAEDDQLGFL
DALAEQFGPDLAELTAAVENFHVSGASPDAASQLLKAAEPRRQELIRRLNLAPGGTASLVRMREAVLTHLRDHPQLRNVD
DDFVHLFTSWFNRGFLVLQRIDWTTPANILEKIIRYEQVHAIRNWDDLRARLAPADRRCYGFFHPQLVDEPLIFVEVALT
LDRPGAIAPLLDLERAPISPKDATTAVFYSISNTQKGLAGISFGNFLIKQVVEEIKRELPNVQSFVTLSPVPGFAKWLKQ
ERADEASALLDDSARAELAVLDAPDWQDDPERADHIKPLLLPLAAAYFLQAKNARGLPLDPVARFHLGNGARLESLNFLG
DRSPNGMRQSHGLMVNYLYALGEIEANHEAFAERAQIAAASAVRKQLPSKPLSSEPRKTNGKTSAPLAIAPPA

Sequences:

>Translated_473_residues
MPQATVDRASEFLGGLFTSLTERGRSLFKSSSDQPKSKDELIALGEALLSRRGEATGVAMAHQLLSGYDGAAEDDQLGFL
DALAEQFGPDLAELTAAVENFHVSGASPDAASQLLKAAEPRRQELIRRLNLAPGGTASLVRMREAVLTHLRDHPQLRNVD
DDFVHLFTSWFNRGFLVLQRIDWTTPANILEKIIRYEQVHAIRNWDDLRARLAPADRRCYGFFHPQLVDEPLIFVEVALT
LDRPGAIAPLLDLERAPISPKDATTAVFYSISNTQKGLAGISFGNFLIKQVVEEIKRELPNVQSFVTLSPVPGFAKWLKQ
ERADEASALLDDSARAELAVLDAPDWQDDPERADHIKPLLLPLAAAYFLQAKNARGLPLDPVARFHLGNGARLESLNFLG
DRSPNGMRQSHGLMVNYLYALGEIEANHEAFAERAQIAAASAVRKQLPSKPLSSEPRKTNGKTSAPLAIAPPA
>Mature_472_residues
PQATVDRASEFLGGLFTSLTERGRSLFKSSSDQPKSKDELIALGEALLSRRGEATGVAMAHQLLSGYDGAAEDDQLGFLD
ALAEQFGPDLAELTAAVENFHVSGASPDAASQLLKAAEPRRQELIRRLNLAPGGTASLVRMREAVLTHLRDHPQLRNVDD
DFVHLFTSWFNRGFLVLQRIDWTTPANILEKIIRYEQVHAIRNWDDLRARLAPADRRCYGFFHPQLVDEPLIFVEVALTL
DRPGAIAPLLDLERAPISPKDATTAVFYSISNTQKGLAGISFGNFLIKQVVEEIKRELPNVQSFVTLSPVPGFAKWLKQE
RADEASALLDDSARAELAVLDAPDWQDDPERADHIKPLLLPLAAAYFLQAKNARGLPLDPVARFHLGNGARLESLNFLGD
RSPNGMRQSHGLMVNYLYALGEIEANHEAFAERAQIAAASAVRKQLPSKPLSSEPRKTNGKTSAPLAIAPPA

Specific function: Unknown

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI110349750, Length=415, Percent_Identity=34.9397590361446, Blast_Score=217, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI71985309, Length=440, Percent_Identity=30.2272727272727, Blast_Score=201, Evalue=7e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.1.1.9

Molecular weight: Translated: 51935; Mature: 51804

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQATVDRASEFLGGLFTSLTERGRSLFKSSSDQPKSKDELIALGEALLSRRGEATGVAM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHH
AHQLLSGYDGAAEDDQLGFLDALAEQFGPDLAELTAAVENFHVSGASPDAASQLLKAAEP
HHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCH
RRQELIRRLNLAPGGTASLVRMREAVLTHLRDHPQLRNVDDDFVHLFTSWFNRGFLVLQR
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEEEE
IDWTTPANILEKIIRYEQVHAIRNWDDLRARLAPADRRCYGFFHPQLVDEPLIFVEVALT
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEECCCHHHHCCCEEEEEEEEE
LDRPGAIAPLLDLERAPISPKDATTAVFYSISNTQKGLAGISFGNFLIKQVVEEIKRELP
ECCCCCCCHHHHCCCCCCCCCCCCEEEEEEECCCCCCHHHCHHHHHHHHHHHHHHHHHCC
NVQSFVTLSPVPGFAKWLKQERADEASALLDDSARAELAVLDAPDWQDDPERADHIKPLL
CHHHEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHH
LPLAAAYFLQAKNARGLPLDPVARFHLGNGARLESLNFLGDRSPNGMRQSHGLMVNYLYA
HHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCHHHHHCCCCCCCCHHHHCCHHHHHHHH
LGEIEANHEAFAERAQIAAASAVRKQLPSKPLSSEPRKTNGKTSAPLAIAPPA
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCC
>Mature Secondary Structure 
PQATVDRASEFLGGLFTSLTERGRSLFKSSSDQPKSKDELIALGEALLSRRGEATGVAM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHH
AHQLLSGYDGAAEDDQLGFLDALAEQFGPDLAELTAAVENFHVSGASPDAASQLLKAAEP
HHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCH
RRQELIRRLNLAPGGTASLVRMREAVLTHLRDHPQLRNVDDDFVHLFTSWFNRGFLVLQR
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEEEE
IDWTTPANILEKIIRYEQVHAIRNWDDLRARLAPADRRCYGFFHPQLVDEPLIFVEVALT
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEECCCHHHHCCCEEEEEEEEE
LDRPGAIAPLLDLERAPISPKDATTAVFYSISNTQKGLAGISFGNFLIKQVVEEIKRELP
ECCCCCCCHHHHCCCCCCCCCCCCEEEEEEECCCCCCHHHCHHHHHHHHHHHHHHHHHCC
NVQSFVTLSPVPGFAKWLKQERADEASALLDDSARAELAVLDAPDWQDDPERADHIKPLL
CHHHEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHH
LPLAAAYFLQAKNARGLPLDPVARFHLGNGARLESLNFLGDRSPNGMRQSHGLMVNYLYA
HHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCHHHHHCCCCCCCCHHHHCCHHHHHHHH
LGEIEANHEAFAERAQIAAASAVRKQLPSKPLSSEPRKTNGKTSAPLAIAPPA
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: malonyl-CoA

Specific reaction: malonyl-CoA = acetyl-CoA + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA