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The map label for this gene is ampG [H]

Identifier: 86747790

GI number: 86747790

Start: 748612

End: 749982

Strand: Direct

Name: ampG [H]

Synonym: RPB_0664

Alternate gene names: 86747790

Gene position: 748612-749982 (Clockwise)

Preceding gene: 86747789

Following gene: 86747795

Centisome position: 14.04

GC content: 67.91

Gene sequence:

>1371_bases
ATGACCTCCAATCCCCCGACCTCCGCTTCCGCCGCACCGAACCACGAGCCCGCGCCGGGCTGGCGCGAGGCGATGACGGT
GTATCTGCAGCCGCGGGTGCTGATCGTGCTGTTTCTCGGCTTCTCGTCCGGGCTGCCGCTGGCGCTGTCGGGCTCGACGC
TGCTGGTGTGGATGCGCGAATCCGGCGTCGATCTCGGCACCATCGGGTTGTTCGCGCTGGTCGGCACGCCCTACACGCTG
AAATTCATCTGGGCGCCGGTGGTCGATGCGTTGCACGTGCCGCTGCTGTCGCGATGGTTCGGCCGCCGCCGCGGTTGGCT
GGTCGCGACGCAACTGCTGCTGATTGTCGCGATCCTGCTGCTGGCGCTGACCGACCCGGCGCATGCGCCGCTGTTCGTCG
CGATCGGTGCATTGCTGGTCGCAGCCGCCTCGGCGACGCAGGACATCGTGGTCGATGCGTTCCGCGTCGAGAGTCTGCCG
GAGAACGAGCAGGCGGCCGGCATGGCGTCCTATGTGGCGGCGTATCGCATCGGCATGCTGATCTCCACCGCAGGCGTGCT
GTTCCTGGTCAGCGCCTATGAGGGCACCGGCCTCGCGCGCGCCGACGCCTGGATGTGGGGCTATGTGACGATGGCCGCCA
TGGTGCTGATCGGCACGGTCACGGCACTGCTCGCGACCGAGCCCGAACAGTCGCGCCGCGCCGAAGCCGCCACCAGCGGC
GAAACCGCATTCACCCGGGTGACGCGGGCGGCTATCGGCGCATTCTCGGAATTTCTCGGCCGCACCGATGCGCTGGCGGT
GCTGGCTTTCGTGGTGCTGTTCAAATTCACCGACGCGTTCTCCGGCACCATGACGGCGCCGTTCGTGATCGATCTCGGCT
TTTCGCGCAATGACTACGCCGCGATTGTGAAAGGCGTCGGCCTCGCCGCCACGCTGATCGGCGGTTTCGCCGGCGGTTAC
GTGGCGCGGCGCTATTCGCTGGTGACGAGCCTGTGGATCGGCGCGGTGCTGCAGGCGCTGTCGAATCTGGCATTCGCCTG
GCTGGCGACAGTCGGCGTCAACCAATGGGCGCTGGCGCTGGCGATTTCGGTCGAGAATTTCACCGGCGCGATCGGCACGG
TGATCTTCGTCGCGTACCTGTCGGCGCTGTGCCAGAACCCGCTGCACACCGCCACGCAATATGCGCTGCTGACGGCGCTG
TCGGCGGTGGGGCGGACGTACTTGTCGGCCGGCGCCGGCTATGTGGCGCAGGCGACCGGCTGGCCGGCGTTCTTCATCAT
CAGCGTCGCGGTGGCCGCGCCCAGCCTGGTGCTCCTGCTGTGGCTGCAACGCCGCGGTCATTTCGCGGCTCTGGGGCCGG
TCAAGGTGTGA

Upstream 100 bases:

>100_bases
TCGTGCGTCACGATCAGCGTGGTGAGGACCGCAACGCCCGGTCAAGCCGGCGCCGACGGTCTCTGATGCCGGGCCTTGGT
CGAATCTGCTACGACCCGGT

Downstream 100 bases:

>100_bases
GGGGGATTTCGCAAAGCGTCATTGCGAGCCAACGGGTCGGCGCTTCGCGCCGCCCGATGACAGGCTCCGCGAAGCAATGC
GGCCTTCTCGAGTGCAGGAT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MTSNPPTSASAAPNHEPAPGWREAMTVYLQPRVLIVLFLGFSSGLPLALSGSTLLVWMRESGVDLGTIGLFALVGTPYTL
KFIWAPVVDALHVPLLSRWFGRRRGWLVATQLLLIVAILLLALTDPAHAPLFVAIGALLVAAASATQDIVVDAFRVESLP
ENEQAAGMASYVAAYRIGMLISTAGVLFLVSAYEGTGLARADAWMWGYVTMAAMVLIGTVTALLATEPEQSRRAEAATSG
ETAFTRVTRAAIGAFSEFLGRTDALAVLAFVVLFKFTDAFSGTMTAPFVIDLGFSRNDYAAIVKGVGLAATLIGGFAGGY
VARRYSLVTSLWIGAVLQALSNLAFAWLATVGVNQWALALAISVENFTGAIGTVIFVAYLSALCQNPLHTATQYALLTAL
SAVGRTYLSAGAGYVAQATGWPAFFIISVAVAAPSLVLLLWLQRRGHFAALGPVKV

Sequences:

>Translated_456_residues
MTSNPPTSASAAPNHEPAPGWREAMTVYLQPRVLIVLFLGFSSGLPLALSGSTLLVWMRESGVDLGTIGLFALVGTPYTL
KFIWAPVVDALHVPLLSRWFGRRRGWLVATQLLLIVAILLLALTDPAHAPLFVAIGALLVAAASATQDIVVDAFRVESLP
ENEQAAGMASYVAAYRIGMLISTAGVLFLVSAYEGTGLARADAWMWGYVTMAAMVLIGTVTALLATEPEQSRRAEAATSG
ETAFTRVTRAAIGAFSEFLGRTDALAVLAFVVLFKFTDAFSGTMTAPFVIDLGFSRNDYAAIVKGVGLAATLIGGFAGGY
VARRYSLVTSLWIGAVLQALSNLAFAWLATVGVNQWALALAISVENFTGAIGTVIFVAYLSALCQNPLHTATQYALLTAL
SAVGRTYLSAGAGYVAQATGWPAFFIISVAVAAPSLVLLLWLQRRGHFAALGPVKV
>Mature_455_residues
TSNPPTSASAAPNHEPAPGWREAMTVYLQPRVLIVLFLGFSSGLPLALSGSTLLVWMRESGVDLGTIGLFALVGTPYTLK
FIWAPVVDALHVPLLSRWFGRRRGWLVATQLLLIVAILLLALTDPAHAPLFVAIGALLVAAASATQDIVVDAFRVESLPE
NEQAAGMASYVAAYRIGMLISTAGVLFLVSAYEGTGLARADAWMWGYVTMAAMVLIGTVTALLATEPEQSRRAEAATSGE
TAFTRVTRAAIGAFSEFLGRTDALAVLAFVVLFKFTDAFSGTMTAPFVIDLGFSRNDYAAIVKGVGLAATLIGGFAGGYV
ARRYSLVTSLWIGAVLQALSNLAFAWLATVGVNQWALALAISVENFTGAIGTVIFVAYLSALCQNPLHTATQYALLTALS
AVGRTYLSAGAGYVAQATGWPAFFIISVAVAAPSLVLLLWLQRRGHFAALGPVKV

Specific function: Probably acts as a permease in the beta-lactamase induction system and in peptidoglycan recycling [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786636, Length=419, Percent_Identity=39.618138424821, Blast_Score=275, Evalue=3e-75,
Organism=Drosophila melanogaster, GI24665528, Length=165, Percent_Identity=32.7272727272727, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24665524, Length=165, Percent_Identity=32.7272727272727, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004752
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48065; Mature: 47933

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSNPPTSASAAPNHEPAPGWREAMTVYLQPRVLIVLFLGFSSGLPLALSGSTLLVWMRE
CCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCEEECCCEEEEEEEC
SGVDLGTIGLFALVGTPYTLKFIWAPVVDALHVPLLSRWFGRRRGWLVATQLLLIVAILL
CCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LALTDPAHAPLFVAIGALLVAAASATQDIVVDAFRVESLPENEQAAGMASYVAAYRIGML
HHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
ISTAGVLFLVSAYEGTGLARADAWMWGYVTMAAMVLIGTVTALLATEPEQSRRAEAATSG
HHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
ETAFTRVTRAAIGAFSEFLGRTDALAVLAFVVLFKFTDAFSGTMTAPFVIDLGFSRNDYA
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHH
AIVKGVGLAATLIGGFAGGYVARRYSLVTSLWIGAVLQALSNLAFAWLATVGVNQWALAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
AISVENFTGAIGTVIFVAYLSALCQNPLHTATQYALLTALSAVGRTYLSAGAGYVAQATG
EEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
WPAFFIISVAVAAPSLVLLLWLQRRGHFAALGPVKV
CHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC
>Mature Secondary Structure 
TSNPPTSASAAPNHEPAPGWREAMTVYLQPRVLIVLFLGFSSGLPLALSGSTLLVWMRE
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCEEECCCEEEEEEEC
SGVDLGTIGLFALVGTPYTLKFIWAPVVDALHVPLLSRWFGRRRGWLVATQLLLIVAILL
CCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LALTDPAHAPLFVAIGALLVAAASATQDIVVDAFRVESLPENEQAAGMASYVAAYRIGML
HHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
ISTAGVLFLVSAYEGTGLARADAWMWGYVTMAAMVLIGTVTALLATEPEQSRRAEAATSG
HHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
ETAFTRVTRAAIGAFSEFLGRTDALAVLAFVVLFKFTDAFSGTMTAPFVIDLGFSRNDYA
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHH
AIVKGVGLAATLIGGFAGGYVARRYSLVTSLWIGAVLQALSNLAFAWLATVGVNQWALAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
AISVENFTGAIGTVIFVAYLSALCQNPLHTATQYALLTALSAVGRTYLSAGAGYVAQATG
EEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
WPAFFIISVAVAAPSLVLLLWLQRRGHFAALGPVKV
CHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]