Click here to switch to the map view.

The map label for this gene is mtgA

Identifier: 86747641

GI number: 86747641

Start: 575982

End: 576665

Strand: Reverse

Name: mtgA

Synonym: RPB_0515

Alternate gene names: 86747641

Gene position: 576665-575982 (Counterclockwise)

Preceding gene: 86747643

Following gene: 86747640

Centisome position: 10.82

GC content: 69.59

Gene sequence:

>684_bases
ATGAGGCGGCTGATCCGCGTCGCGCTGCTGACGCTGCTGCTGCTGGTCGCGGCGCCCTACGTGCTGACGCTGGTGTATGG
CGCGGGCCAGCCGGTCTCGACGCTGATGGTCTGGCGTTGGTTGGCGGGCGCGACGGTGACCCGGCAATGGGTCGACATCG
AACGGATGGCGCCGGCCTTGCCGCGCACCGTGGTGGCCTCCGAGGACGCCAAATTCTGCAGCCACAGCGGCATCGACTGG
GACTCGGTGCGCGACGTACTCGACGATCTGCAGGACGGCGGCGAGGCCAGCCGCGGCGGCTCCACCATCACACAGCAGGT
CGCCAAGAACCTGTTCCTGTGGCCGGGCCGCAGCGTGGTGCGCAAGGCGCTGGAATTTCCGTTGGCGATGTGGATCGACC
TGGTGCTGTCGAAGCAGCGCATCCTCGAACTCTACCTCAACATCGCCGAATGGGGGCCGGACGGGCAGTTCGGCGCCGAG
GCCGGCGCCGCCTATGCGTTCGGCCGCTCGGCCGCCCAGCTGACGCCGCAGGAGGCGGCGCTGATGGCGTCGATCCTGCC
CAACCCGCGGGTGCGCAGCGCCAAGAAGCCCGGACCAGGCGTGCGCCGGCTCGCCGCCACCTATGTGGCGCGGGCGCGAT
CGGCCGAATTGCAGCAATGCTGGCGCGAAAATAGCGGCTCCTGA

Upstream 100 bases:

>100_bases
GTCAATTCGGCGCTCGACCGGGCGGTGCATCAGGGGGCGCAAAGATGCCGGCCAATCCGACCCGCAACCTCGCGAGCCCT
CCGACCGGCGCCGGGTCGGC

Downstream 100 bases:

>100_bases
GGCGATTTACCTCCTCCGGCGGTCTAGCCATCCTGCAAAGCTTGCTCTATAAGCCCGGCCTAGCTTTACGCCTGCGCGCG
AGCGCCGGGCCGTCCCGCCG

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MRRLIRVALLTLLLLVAAPYVLTLVYGAGQPVSTLMVWRWLAGATVTRQWVDIERMAPALPRTVVASEDAKFCSHSGIDW
DSVRDVLDDLQDGGEASRGGSTITQQVAKNLFLWPGRSVVRKALEFPLAMWIDLVLSKQRILELYLNIAEWGPDGQFGAE
AGAAYAFGRSAAQLTPQEAALMASILPNPRVRSAKKPGPGVRRLAATYVARARSAELQQCWRENSGS

Sequences:

>Translated_227_residues
MRRLIRVALLTLLLLVAAPYVLTLVYGAGQPVSTLMVWRWLAGATVTRQWVDIERMAPALPRTVVASEDAKFCSHSGIDW
DSVRDVLDDLQDGGEASRGGSTITQQVAKNLFLWPGRSVVRKALEFPLAMWIDLVLSKQRILELYLNIAEWGPDGQFGAE
AGAAYAFGRSAAQLTPQEAALMASILPNPRVRSAKKPGPGVRRLAATYVARARSAELQQCWRENSGS
>Mature_227_residues
MRRLIRVALLTLLLLVAAPYVLTLVYGAGQPVSTLMVWRWLAGATVTRQWVDIERMAPALPRTVVASEDAKFCSHSGIDW
DSVRDVLDDLQDGGEASRGGSTITQQVAKNLFLWPGRSVVRKALEFPLAMWIDLVLSKQRILELYLNIAEWGPDGQFGAE
AGAAYAFGRSAAQLTPQEAALMASILPNPRVRSAKKPGPGVRRLAATYVARARSAELQQCWRENSGS

Specific function: Cell wall formation

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family

Homologues:

Organism=Escherichia coli, GI1789601, Length=208, Percent_Identity=42.7884615384615, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI87082258, Length=147, Percent_Identity=37.4149659863946, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1786343, Length=128, Percent_Identity=40.625, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788867, Length=164, Percent_Identity=34.7560975609756, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTGA_RHOP2 (Q2J2T4)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_484137.1
- ProteinModelPortal:   Q2J2T4
- SMR:   Q2J2T4
- STRING:   Q2J2T4
- GeneID:   3909419
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_0515
- eggNOG:   COG0744
- HOGENOM:   HBG685698
- OMA:   MMSEDGQ
- ProtClustDB:   PRK00056
- BioCyc:   RPAL316058:RPB_0515-MONOMER
- HAMAP:   MF_00766
- InterPro:   IPR001264
- InterPro:   IPR011812
- TIGRFAMs:   TIGR02070

Pfam domain/function: PF00912 Transgly

EC number: 2.4.2.- [C]

Molecular weight: Translated: 24873; Mature: 24873

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x159ddba8)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLIRVALLTLLLLVAAPYVLTLVYGAGQPVSTLMVWRWLAGATVTRQWVDIERMAPAL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
PRTVVASEDAKFCSHSGIDWDSVRDVLDDLQDGGEASRGGSTITQQVAKNLFLWPGRSVV
CHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHH
RKALEFPLAMWIDLVLSKQRILELYLNIAEWGPDGQFGAEAGAAYAFGRSAAQLTPQEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHCCHHHHH
LMASILPNPRVRSAKKPGPGVRRLAATYVARARSAELQQCWRENSGS
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure
MRRLIRVALLTLLLLVAAPYVLTLVYGAGQPVSTLMVWRWLAGATVTRQWVDIERMAPAL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
PRTVVASEDAKFCSHSGIDWDSVRDVLDDLQDGGEASRGGSTITQQVAKNLFLWPGRSVV
CHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHH
RKALEFPLAMWIDLVLSKQRILELYLNIAEWGPDGQFGAEAGAAYAFGRSAAQLTPQEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHCCHHHHH
LMASILPNPRVRSAKKPGPGVRRLAATYVARARSAELQQCWRENSGS
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA