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The map label for this gene is yggW [C]

Identifier: 86747549

GI number: 86747549

Start: 466138

End: 467310

Strand: Reverse

Name: yggW [C]

Synonym: RPB_0423

Alternate gene names: 86747549

Gene position: 467310-466138 (Counterclockwise)

Preceding gene: 86747550

Following gene: 86747547

Centisome position: 8.76

GC content: 68.03

Gene sequence:

>1173_bases
TTGGGCGCTGAATCCGATCGCGCCTTCGGCGTCCAAGCCTTTGGTGTCTACGTGCACTGGCCCTTCTGCCTGTCGAAGTG
CCCGTATTGCGACTTCAACAGCCATGTCCGGCACGCCGCGATCGACGAGGACCGCTTCGCTCGCGCCTTCGCCCGCGAGA
TCGAAGCCACCGCGCAGCGGATCGGTCCGCGGGACGTCACGTCGATCTTTCTCGGCGGCGGCACGCCGTCGCTGATGCAG
CCGCAGACCGTCGGCGCCATCCTCGACGCCATCGGCAAATACTGGCGCGTCGCGCCCGATGTCGAAGTGAGCCTCGAAGC
CAATCCGACCAGCGTCGAGGCGACGCGGTTTCGCGGCTATCGCGCGGCCGGCGTCAACCGCGTCTCGCTCGGCGTGCAGG
CGCTCGACGACGCCTCGCTGAAGACGCTCGGCCGCCTGCACACGGCACAGGAAGCAATGGAAGCCGTGGCGATCGCGCGC
GCGGCGTTCGATCGCTATTCGTTCGACCTGATCTACGCGCGCCCGGGGCAAACTCCCGCGATGTGGGAGGCCGAACTGCG
CCGCGCCATCGGCGAGGCGGCCGAACATCTGTCGCTGTATCAGCTCACGATCGAGGCCGAGACGCCGTTCTTTGCGCTGC
ATCGCGCCGGCAAGCTGCAGACGCCGGACGAGTCCGCGTCGCGCGCACTCTACGATGTCACACAATCGGTCTGCGCCGAG
CTCGGACTCCCCGCTTACGAGATTTCCAATCACGCCCGCCCGGGTGCCGAGTGCAAACACAATCTCGTCTACTGGCGCGG
TCAGGAATATGCCGGGATCGGCCCCGGCGCGCATGGCCGGCTCGACATCGGCGGCACGCGCTACGCGATCGCCACCGAAA
AGCGGCCGGAGAGCTGGCTGATGCGGGTCGAAGCGAGCGGCACCGGCGTGGTGACCGATGACCGTCTCAACAGCGAAGAG
CGCGCCGACGAATTCCTGCTGATGGGGCTGCGGCTCGCCGAAGGCATCGACCCGCGGCGCTATCAGGCGCTGGCCGGCCG
TTCGCTCGATCCATCGCGGATCGCGATCCTGCGCGAGGAAGGCGCCATCGCGGTCGACGCCGACGGAAGGCTGCGCGTGA
CGCAAGCCGGCTTTCCGGTGCTGGATGCCGTCGTGGCGGATCTGGCGGCGTAG

Upstream 100 bases:

>100_bases
TTCGGCGAAATGACCAGCCTCGAGAAGCACGGCCTGCCGCCGCTCGGGCTCGGCCTGTCGCATCGCGCCCGCGCCTTCGT
CGAACTGGCGGAGATCTGCC

Downstream 100 bases:

>100_bases
TCATCACGCCAGAATTCCGGCTTCGCCGCTGTGCGGCGCCCCGGATCGACTATGACGGCAGGGACTACGCCCCGAAGCTC
TTCGGCGATCCAGCCACCGC

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MGAESDRAFGVQAFGVYVHWPFCLSKCPYCDFNSHVRHAAIDEDRFARAFAREIEATAQRIGPRDVTSIFLGGGTPSLMQ
PQTVGAILDAIGKYWRVAPDVEVSLEANPTSVEATRFRGYRAAGVNRVSLGVQALDDASLKTLGRLHTAQEAMEAVAIAR
AAFDRYSFDLIYARPGQTPAMWEAELRRAIGEAAEHLSLYQLTIEAETPFFALHRAGKLQTPDESASRALYDVTQSVCAE
LGLPAYEISNHARPGAECKHNLVYWRGQEYAGIGPGAHGRLDIGGTRYAIATEKRPESWLMRVEASGTGVVTDDRLNSEE
RADEFLLMGLRLAEGIDPRRYQALAGRSLDPSRIAILREEGAIAVDADGRLRVTQAGFPVLDAVVADLAA

Sequences:

>Translated_390_residues
MGAESDRAFGVQAFGVYVHWPFCLSKCPYCDFNSHVRHAAIDEDRFARAFAREIEATAQRIGPRDVTSIFLGGGTPSLMQ
PQTVGAILDAIGKYWRVAPDVEVSLEANPTSVEATRFRGYRAAGVNRVSLGVQALDDASLKTLGRLHTAQEAMEAVAIAR
AAFDRYSFDLIYARPGQTPAMWEAELRRAIGEAAEHLSLYQLTIEAETPFFALHRAGKLQTPDESASRALYDVTQSVCAE
LGLPAYEISNHARPGAECKHNLVYWRGQEYAGIGPGAHGRLDIGGTRYAIATEKRPESWLMRVEASGTGVVTDDRLNSEE
RADEFLLMGLRLAEGIDPRRYQALAGRSLDPSRIAILREEGAIAVDADGRLRVTQAGFPVLDAVVADLAA
>Mature_389_residues
GAESDRAFGVQAFGVYVHWPFCLSKCPYCDFNSHVRHAAIDEDRFARAFAREIEATAQRIGPRDVTSIFLGGGTPSLMQP
QTVGAILDAIGKYWRVAPDVEVSLEANPTSVEATRFRGYRAAGVNRVSLGVQALDDASLKTLGRLHTAQEAMEAVAIARA
AFDRYSFDLIYARPGQTPAMWEAELRRAIGEAAEHLSLYQLTIEAETPFFALHRAGKLQTPDESASRALYDVTQSVCAEL
GLPAYEISNHARPGAECKHNLVYWRGQEYAGIGPGAHGRLDIGGTRYAIATEKRPESWLMRVEASGTGVVTDDRLNSEER
ADEFLLMGLRLAEGIDPRRYQALAGRSLDPSRIAILREEGAIAVDADGRLRVTQAGFPVLDAVVADLAA

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=300, Percent_Identity=40.3333333333333, Blast_Score=228, Evalue=1e-59,
Organism=Escherichia coli, GI1789325, Length=341, Percent_Identity=35.4838709677419, Blast_Score=211, Evalue=6e-56,
Organism=Escherichia coli, GI87082341, Length=271, Percent_Identity=27.6752767527675, Blast_Score=101, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 42550; Mature: 42419

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAESDRAFGVQAFGVYVHWPFCLSKCPYCDFNSHVRHAAIDEDRFARAFAREIEATAQR
CCCCCCCCCCEEEEEEEEECHHHHCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHH
IGPRDVTSIFLGGGTPSLMQPQTVGAILDAIGKYWRVAPDVEVSLEANPTSVEATRFRGY
CCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEHHHHCCE
RAAGVNRVSLGVQALDDASLKTLGRLHTAQEAMEAVAIARAAFDRYSFDLIYARPGQTPA
ECCCCCEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCH
MWEAELRRAIGEAAEHLSLYQLTIEAETPFFALHRAGKLQTPDESASRALYDVTQSVCAE
HHHHHHHHHHHHHHHCEEEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
LGLPAYEISNHARPGAECKHNLVYWRGQEYAGIGPGAHGRLDIGGTRYAIATEKRPESWL
HCCCHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEECCCCEEEEEECCCCCHHE
MRVEASGTGVVTDDRLNSEERADEFLLMGLRLAEGIDPRRYQALAGRSLDPSRIAILREE
EEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHEEEEECC
GAIAVDADGRLRVTQAGFPVLDAVVADLAA
CCEEECCCCCEEEEECCCHHHHHHHHHHCC
>Mature Secondary Structure 
GAESDRAFGVQAFGVYVHWPFCLSKCPYCDFNSHVRHAAIDEDRFARAFAREIEATAQR
CCCCCCCCCEEEEEEEEECHHHHCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHH
IGPRDVTSIFLGGGTPSLMQPQTVGAILDAIGKYWRVAPDVEVSLEANPTSVEATRFRGY
CCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEHHHHCCE
RAAGVNRVSLGVQALDDASLKTLGRLHTAQEAMEAVAIARAAFDRYSFDLIYARPGQTPA
ECCCCCEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCH
MWEAELRRAIGEAAEHLSLYQLTIEAETPFFALHRAGKLQTPDESASRALYDVTQSVCAE
HHHHHHHHHHHHHHHCEEEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
LGLPAYEISNHARPGAECKHNLVYWRGQEYAGIGPGAHGRLDIGGTRYAIATEKRPESWL
HCCCHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEECCCCEEEEEECCCCCHHE
MRVEASGTGVVTDDRLNSEERADEFLLMGLRLAEGIDPRRYQALAGRSLDPSRIAILREE
EEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHEEEEECC
GAIAVDADGRLRVTQAGFPVLDAVVADLAA
CCEEECCCCCEEEEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]