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The map label for this gene is mcp4 [H]

Identifier: 86747318

GI number: 86747318

Start: 214614

End: 216680

Strand: Reverse

Name: mcp4 [H]

Synonym: RPB_0192

Alternate gene names: 86747318

Gene position: 216680-214614 (Counterclockwise)

Preceding gene: 86747320

Following gene: 86747317

Centisome position: 4.06

GC content: 63.09

Gene sequence:

>2067_bases
ATGACCAGCAGAACCACGCGCAACGGCGAGCCGCGATCGCCTGGATTGTTCGACGTCTTTACCAACAGGAGAATCGGCAC
CAAGGTCGCGATCGGATTTGTTCTGGTCCAGGTCCTGATGGTTGTTCTCGCCGTCCTGAATTACTCCTCCTTCGAACATG
TCAGGCAGGCCTTCGTGGCGCTCGACCAGCGGGTTCAGGTCGTGGGCATTGTCCGCGACGTCGATCGCGGCTTCACCGCC
TTTCGTCGGTTCGTGCGCGAATACAGCCTCACCGGTGACGAGGCGCTGATCAGCGAAGCAGAGAGCCGCCAGAACGCTCT
GCGGCAGAGCATCGCGCAGGGCCTGAAGGAGATCCACGATCCGTCTCGCCTGGCCAAGATGAGGGAGATCAGTCAGGCGT
TCGACGCCTACACCACGTCCTTCGCCGACGTGTTCCGAATGCGTCGCGACCAGAGCAAGCTGATCCGTGAGGTGCTGGAT
CCCACCGGTCAGCAGGCACGACTTAAGCTTGAGCAACTTCAAGCAGCGATTACTGCCAACGATGGCGGGGAGACCACTTC
GCTCCTCGTCGCTGAGGCGGTGAAGCAACTGCTGCTGCTGAGGCTCGATGTGAATAAGGTGCTCGGTCGTCACGACCAAG
CCGCCGCGGACGCCGCGGAGAAGGCCTTAGCCGACCTCAAGACAGCGATGTCGGCGCTAAAGACTGCGATCGGTTCATCG
GCCGGCCGCAAGCAAATCGGCGAGATCGAGGTCGACATCAAGAACTACGCGAATGCTTATCAGAAGGCGTCGCGCGTTGC
CCACGAGATCGAAGTGCTGGTCAATGGCACGATGCCGAAAGCCGCGACGGCGATCGCAGGCGATGCGGCGAACATCAAGC
AGTCCGGAATTGCCGACCAGCAGAAGATCGCCAAGGACACCGAAGCATTGCTCGGCGACACCAAGAGTCAGATCCTGATC
ATCACGGCCGGCGTGCTGGTCGTGGGCATGTTGCTCGCATGGCTGATCGGCCGTGCGATCTCGCGGCCCATCGTTCAGAT
GTCGGGCGCGATGAAGGAACTGGCCGGCGGCAATCTGAATGTCGAGGTGGTCGGCTCCGGGCGGCTGGACGAGATCGGTC
TTATGGCGTGCACCGTCGAGGTCTTCAAGAACAATGCACTCGAAGTGATCCGGCTGAGGGAAGAGCAAGAGGAAGCCGAG
CGCCGTTCCGCGGCTCAACACAAGGCCGAGATGCAGCAGCTTGCCGACGAATTCGAAGGCGCCGTCGGTGAGATCATCCA
GACCGTGACTTCGGCCTCTACGGAGCTCGAGGCTTCGGCCGGCACACTCACGACGACCGCCGATCGCTCCCAGGAGCTGG
CCACGTCGGTGGCGGCGGCGTCGGAGCAGGCCTCGGCCAACGTGCAGTCGGTGGCGTCCGCGACCGAGGAGATGGCGTCG
TCGATCTCCGAGATCAGCCGCCAGGTGCAGACTTCGGCGCGGATCGCGGGTGAGGCTGTCGATCAAGCCCGCAAAACCAA
CGACCGCATCGGTCATCTTGCCGACGCAGCGAACCGAATTGGCGACGTTGTCGAGTTGATCAATACGATCGCTGGCCAGA
CCAATCTGCTGGCGCTCAACGCCACGATCGAGGCGGCCCGCGCCGGCGACGCCGGTCGCGGCTTCGCGGTCGTGGCACAG
GAGGTCAAGGCGCTCGCCGAGCAGACAGCCAAGGCAACCGGCGAAATCAGCCAGCAGATTTCCGGAATGCAGGCCGCGAC
CCAGGATTCGGTCGGGGCCATCCGTGAAATCGGCGGCACCATCGAACGGATGTCGGAGATCGCCTCGACGATTGCCTCCG
CCGTGGAAGAACAAGGTGCGGCCACGCAGGAGATCTCCCGCAACGTGCAGCAGGCCGCGCAAGGTACCCAGCAAGTTTCG
TCGAACATCTGCGATGTTCAGCGGGGCGCCACTGAGACCGGTTCGGCGTCGAGCCAAGTGCTGGCGGCGGCGCAATCGCT
GTCGCGGGACAGCAACCGGCTCAAGGACGAGGTCACCCGTTTCGTGGAGACGGTGCGGGCGGCGTGA

Upstream 100 bases:

>100_bases
ACTGCTCGATGAGGTGTTCCGCTTGTCGTCGTCGCGACGACCGGGATGGCGATCACCTCTGAATGAATAGACACCAAACG
CTATCAACCGGAACCCTGAG

Downstream 100 bases:

>100_bases
GGAGATTTCGGAGCGGCGTCGATGCGTTTGTCGACCGTCGTCGGATATTTGATAAGCCGAGGTGTCGAGATGTCGCTAGA
TAGCCGCTCAAACTGCCGCA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 688; Mature: 687

Protein sequence:

>688_residues
MTSRTTRNGEPRSPGLFDVFTNRRIGTKVAIGFVLVQVLMVVLAVLNYSSFEHVRQAFVALDQRVQVVGIVRDVDRGFTA
FRRFVREYSLTGDEALISEAESRQNALRQSIAQGLKEIHDPSRLAKMREISQAFDAYTTSFADVFRMRRDQSKLIREVLD
PTGQQARLKLEQLQAAITANDGGETTSLLVAEAVKQLLLLRLDVNKVLGRHDQAAADAAEKALADLKTAMSALKTAIGSS
AGRKQIGEIEVDIKNYANAYQKASRVAHEIEVLVNGTMPKAATAIAGDAANIKQSGIADQQKIAKDTEALLGDTKSQILI
ITAGVLVVGMLLAWLIGRAISRPIVQMSGAMKELAGGNLNVEVVGSGRLDEIGLMACTVEVFKNNALEVIRLREEQEEAE
RRSAAQHKAEMQQLADEFEGAVGEIIQTVTSASTELEASAGTLTTTADRSQELATSVAAASEQASANVQSVASATEEMAS
SISEISRQVQTSARIAGEAVDQARKTNDRIGHLADAANRIGDVVELINTIAGQTNLLALNATIEAARAGDAGRGFAVVAQ
EVKALAEQTAKATGEISQQISGMQAATQDSVGAIREIGGTIERMSEIASTIASAVEEQGAATQEISRNVQQAAQGTQQVS
SNICDVQRGATETGSASSQVLAAAQSLSRDSNRLKDEVTRFVETVRAA

Sequences:

>Translated_688_residues
MTSRTTRNGEPRSPGLFDVFTNRRIGTKVAIGFVLVQVLMVVLAVLNYSSFEHVRQAFVALDQRVQVVGIVRDVDRGFTA
FRRFVREYSLTGDEALISEAESRQNALRQSIAQGLKEIHDPSRLAKMREISQAFDAYTTSFADVFRMRRDQSKLIREVLD
PTGQQARLKLEQLQAAITANDGGETTSLLVAEAVKQLLLLRLDVNKVLGRHDQAAADAAEKALADLKTAMSALKTAIGSS
AGRKQIGEIEVDIKNYANAYQKASRVAHEIEVLVNGTMPKAATAIAGDAANIKQSGIADQQKIAKDTEALLGDTKSQILI
ITAGVLVVGMLLAWLIGRAISRPIVQMSGAMKELAGGNLNVEVVGSGRLDEIGLMACTVEVFKNNALEVIRLREEQEEAE
RRSAAQHKAEMQQLADEFEGAVGEIIQTVTSASTELEASAGTLTTTADRSQELATSVAAASEQASANVQSVASATEEMAS
SISEISRQVQTSARIAGEAVDQARKTNDRIGHLADAANRIGDVVELINTIAGQTNLLALNATIEAARAGDAGRGFAVVAQ
EVKALAEQTAKATGEISQQISGMQAATQDSVGAIREIGGTIERMSEIASTIASAVEEQGAATQEISRNVQQAAQGTQQVS
SNICDVQRGATETGSASSQVLAAAQSLSRDSNRLKDEVTRFVETVRAA
>Mature_687_residues
TSRTTRNGEPRSPGLFDVFTNRRIGTKVAIGFVLVQVLMVVLAVLNYSSFEHVRQAFVALDQRVQVVGIVRDVDRGFTAF
RRFVREYSLTGDEALISEAESRQNALRQSIAQGLKEIHDPSRLAKMREISQAFDAYTTSFADVFRMRRDQSKLIREVLDP
TGQQARLKLEQLQAAITANDGGETTSLLVAEAVKQLLLLRLDVNKVLGRHDQAAADAAEKALADLKTAMSALKTAIGSSA
GRKQIGEIEVDIKNYANAYQKASRVAHEIEVLVNGTMPKAATAIAGDAANIKQSGIADQQKIAKDTEALLGDTKSQILII
TAGVLVVGMLLAWLIGRAISRPIVQMSGAMKELAGGNLNVEVVGSGRLDEIGLMACTVEVFKNNALEVIRLREEQEEAER
RSAAQHKAEMQQLADEFEGAVGEIIQTVTSASTELEASAGTLTTTADRSQELATSVAAASEQASANVQSVASATEEMASS
ISEISRQVQTSARIAGEAVDQARKTNDRIGHLADAANRIGDVVELINTIAGQTNLLALNATIEAARAGDAGRGFAVVAQE
VKALAEQTAKATGEISQQISGMQAATQDSVGAIREIGGTIERMSEIASTIASAVEEQGAATQEISRNVQQAAQGTQQVSS
NICDVQRGATETGSASSQVLAAAQSLSRDSNRLKDEVTRFVETVRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=323, Percent_Identity=30.030959752322, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1787690, Length=359, Percent_Identity=28.9693593314763, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1788194, Length=330, Percent_Identity=29.0909090909091, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI2367378, Length=332, Percent_Identity=29.8192771084337, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI1789453, Length=205, Percent_Identity=33.6585365853659, Blast_Score=90, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 73313; Mature: 73181

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRTTRNGEPRSPGLFDVFTNRRIGTKVAIGFVLVQVLMVVLAVLNYSSFEHVRQAFVA
CCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LDQRVQVVGIVRDVDRGFTAFRRFVREYSLTGDEALISEAESRQNALRQSIAQGLKEIHD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PSRLAKMREISQAFDAYTTSFADVFRMRRDQSKLIREVLDPTGQQARLKLEQLQAAITAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
DGGETTSLLVAEAVKQLLLLRLDVNKVLGRHDQAAADAAEKALADLKTAMSALKTAIGSS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AGRKQIGEIEVDIKNYANAYQKASRVAHEIEVLVNGTMPKAATAIAGDAANIKQSGIADQ
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHCCCCHH
QKIAKDTEALLGDTKSQILIITAGVLVVGMLLAWLIGRAISRPIVQMSGAMKELAGGNLN
HHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VEVVGSGRLDEIGLMACTVEVFKNNALEVIRLREEQEEAERRSAAQHKAEMQQLADEFEG
EEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGEIIQTVTSASTELEASAGTLTTTADRSQELATSVAAASEQASANVQSVASATEEMAS
HHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SISEISRQVQTSARIAGEAVDQARKTNDRIGHLADAANRIGDVVELINTIAGQTNLLALN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
ATIEAARAGDAGRGFAVVAQEVKALAEQTAKATGEISQQISGMQAATQDSVGAIREIGGT
CHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IERMSEIASTIASAVEEQGAATQEISRNVQQAAQGTQQVSSNICDVQRGATETGSASSQV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LAAAQSLSRDSNRLKDEVTRFVETVRAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSRTTRNGEPRSPGLFDVFTNRRIGTKVAIGFVLVQVLMVVLAVLNYSSFEHVRQAFVA
CCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LDQRVQVVGIVRDVDRGFTAFRRFVREYSLTGDEALISEAESRQNALRQSIAQGLKEIHD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PSRLAKMREISQAFDAYTTSFADVFRMRRDQSKLIREVLDPTGQQARLKLEQLQAAITAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
DGGETTSLLVAEAVKQLLLLRLDVNKVLGRHDQAAADAAEKALADLKTAMSALKTAIGSS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AGRKQIGEIEVDIKNYANAYQKASRVAHEIEVLVNGTMPKAATAIAGDAANIKQSGIADQ
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHCCCCHH
QKIAKDTEALLGDTKSQILIITAGVLVVGMLLAWLIGRAISRPIVQMSGAMKELAGGNLN
HHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VEVVGSGRLDEIGLMACTVEVFKNNALEVIRLREEQEEAERRSAAQHKAEMQQLADEFEG
EEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGEIIQTVTSASTELEASAGTLTTTADRSQELATSVAAASEQASANVQSVASATEEMAS
HHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SISEISRQVQTSARIAGEAVDQARKTNDRIGHLADAANRIGDVVELINTIAGQTNLLALN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
ATIEAARAGDAGRGFAVVAQEVKALAEQTAKATGEISQQISGMQAATQDSVGAIREIGGT
CHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IERMSEIASTIASAVEEQGAATQEISRNVQQAAQGTQQVSSNICDVQRGATETGSASSQV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LAAAQSLSRDSNRLKDEVTRFVETVRAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]