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The map label for this gene is ucpA [H]

Identifier: 86747149

GI number: 86747149

Start: 22420

End: 23301

Strand: Reverse

Name: ucpA [H]

Synonym: RPB_0022

Alternate gene names: 86747149

Gene position: 23301-22420 (Counterclockwise)

Preceding gene: 86747150

Following gene: 86747147

Centisome position: 0.44

GC content: 66.44

Gene sequence:

>882_bases
ATGTCATCACTCGCGGGCAAGACGCTGTTCATCACCGGGGCCAGCCGCGGCATCGGGCTGGCGATCGCGCTGCGGGCGGC
GCGCGACGGCGCCAATGTGGCGATCGCCGCCAAGACCGCCGAGCCGCAGCCCAAGCTGAAGGGCACGATCTACACTGCGG
CCGACGAGATCCGCGCCGCCGGCGGGCAGGCGCTGCCGCTGATCTGCGACATCCGCGACGAGGCGCAAGTGATCGCCGCG
ATCGACAAGACGGTGGCCGAATTCGGCGGCATCGACATCTGCGTCAACAATGCCAGCGCGATCAGCCTGACCAATTCGCA
GGCGACCGACATGAAGCGCTACGACCTGATGATGGGCATCAACAGCCGCGGCACCTTCATGGTGTCGAAATACTGCATCC
CGCATCTGAAGAAGGCGGCCAACCCGCACATCCTGATGCTGTCGCCGCCGCTCGACATGAAGGCGAAATGGTTCGCGGCC
TCGACCGCCTACACCATGGCCAAATTCGGCATGAGCATGGTGGTGCTGGGATTGTCGGGTGAATTGAAGGGCGCGGGAAT
CGCCGTCAACGCGCTGTGGCCGCGCACCACCATCGCCACCGCCGCGGTCGGCAATCTCTTGGGCGGCGACGCGATGATGC
GCGCCAGCCGCACGCCGGAGATCATGGGCGACGCCGCGCACGCGATCCTGACCAAGCCGTCGCGCGACTTCACCGGGCAG
TTCTGCATCGACGACAAGGTGCTGTATGAGGCCGGCGTCACCGATTTCGAGCGCTACCGCGTCGATCCGAGCGTGCCATT
GATGTCGGATTTCTTCGTGCCGGACGACGACGTGCCCCCGCCCGGCGTCACCGTCGCGTCGCTGCCGGGCGCGAAGGGGT
AG

Upstream 100 bases:

>100_bases
GCCGGAAGACCGCAATTAGCACCTCCGCCGAAGCCGCTTCGATCTGATCGCGTCCCGCGCTACAAGGGACGAAAGCTGGT
CGGCGCAAAGGGAGGAATTC

Downstream 100 bases:

>100_bases
GGCATTTTATAGGCGCCGTGCGCGCCCCGAGCACTGCGAACTCCCTCTCCCGCGTGCGGGAGAGGGTTGGGGTGAGGGCG
ACGCGAGCGGTGGAGTCTCG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSSLAGKTLFITGASRGIGLAIALRAARDGANVAIAAKTAEPQPKLKGTIYTAADEIRAAGGQALPLICDIRDEAQVIAA
IDKTVAEFGGIDICVNNASAISLTNSQATDMKRYDLMMGINSRGTFMVSKYCIPHLKKAANPHILMLSPPLDMKAKWFAA
STAYTMAKFGMSMVVLGLSGELKGAGIAVNALWPRTTIATAAVGNLLGGDAMMRASRTPEIMGDAAHAILTKPSRDFTGQ
FCIDDKVLYEAGVTDFERYRVDPSVPLMSDFFVPDDDVPPPGVTVASLPGAKG

Sequences:

>Translated_293_residues
MSSLAGKTLFITGASRGIGLAIALRAARDGANVAIAAKTAEPQPKLKGTIYTAADEIRAAGGQALPLICDIRDEAQVIAA
IDKTVAEFGGIDICVNNASAISLTNSQATDMKRYDLMMGINSRGTFMVSKYCIPHLKKAANPHILMLSPPLDMKAKWFAA
STAYTMAKFGMSMVVLGLSGELKGAGIAVNALWPRTTIATAAVGNLLGGDAMMRASRTPEIMGDAAHAILTKPSRDFTGQ
FCIDDKVLYEAGVTDFERYRVDPSVPLMSDFFVPDDDVPPPGVTVASLPGAKG
>Mature_292_residues
SSLAGKTLFITGASRGIGLAIALRAARDGANVAIAAKTAEPQPKLKGTIYTAADEIRAAGGQALPLICDIRDEAQVIAAI
DKTVAEFGGIDICVNNASAISLTNSQATDMKRYDLMMGINSRGTFMVSKYCIPHLKKAANPHILMLSPPLDMKAKWFAAS
TAYTMAKFGMSMVVLGLSGELKGAGIAVNALWPRTTIATAAVGNLLGGDAMMRASRTPEIMGDAAHAILTKPSRDFTGQF
CIDDKVLYEAGVTDFERYRVDPSVPLMSDFFVPDDDVPPPGVTVASLPGAKG

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254986, Length=276, Percent_Identity=58.3333333333333, Blast_Score=323, Evalue=1e-88,
Organism=Homo sapiens, GI209862901, Length=199, Percent_Identity=28.1407035175879, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI19923983, Length=199, Percent_Identity=28.1407035175879, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI19923817, Length=207, Percent_Identity=27.536231884058, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI10190704, Length=211, Percent_Identity=29.8578199052133, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI225579078, Length=209, Percent_Identity=27.7511961722488, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI4504505, Length=192, Percent_Identity=27.6041666666667, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI87082100, Length=195, Percent_Identity=34.3589743589744, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789208, Length=193, Percent_Identity=29.5336787564767, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71982365, Length=273, Percent_Identity=60.0732600732601, Blast_Score=340, Evalue=6e-94,
Organism=Caenorhabditis elegans, GI17558628, Length=278, Percent_Identity=59.7122302158273, Blast_Score=325, Evalue=2e-89,
Organism=Caenorhabditis elegans, GI17559104, Length=201, Percent_Identity=28.3582089552239, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=208, Percent_Identity=32.2115384615385, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=199, Percent_Identity=28.1407035175879, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=147, Percent_Identity=31.2925170068027, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17555612, Length=280, Percent_Identity=25.7142857142857, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=202, Percent_Identity=28.2178217821782, Blast_Score=64, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=225, Percent_Identity=28, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI21357673, Length=278, Percent_Identity=62.589928057554, Blast_Score=352, Evalue=2e-97,
Organism=Drosophila melanogaster, GI28571526, Length=195, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24644339, Length=196, Percent_Identity=29.0816326530612, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI23397609, Length=192, Percent_Identity=28.6458333333333, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21357041, Length=199, Percent_Identity=29.6482412060301, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355319, Length=223, Percent_Identity=26.9058295964126, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30799; Mature: 30668

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLAGKTLFITGASRGIGLAIALRAARDGANVAIAAKTAEPQPKLKGTIYTAADEIRAA
CCCCCCCEEEEEECCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCEEEEECHHHHHHC
GGQALPLICDIRDEAQVIAAIDKTVAEFGGIDICVNNASAISLTNSQATDMKRYDLMMGI
CCCCCEEEEECCCCHHHHHHHHHHHHHHCCEEEEECCCCEEEECCCCCCCHHHEEEEEEC
NSRGTFMVSKYCIPHLKKAANPHILMLSPPLDMKAKWFAASTAYTMAKFGMSMVVLGLSG
CCCCCEEEEHHHHHHHHHCCCCEEEEECCCCCCCEEEEEHHHHHHHHHCCCEEEEEECCC
ELKGAGIAVNALWPRTTIATAAVGNLLGGDAMMRASRTPEIMGDAAHAILTKPSRDFTGQ
CCCCCCEEEEEECCCHHHHHHHHHHHHCCHHHHHCCCCCHHHCCHHHHEEECCCCCCCCE
FCIDDKVLYEAGVTDFERYRVDPSVPLMSDFFVPDDDVPPPGVTVASLPGAKG
EEECCEEEECCCCCCHHHEECCCCCCCHHCCCCCCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure 
SSLAGKTLFITGASRGIGLAIALRAARDGANVAIAAKTAEPQPKLKGTIYTAADEIRAA
CCCCCCEEEEEECCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCEEEEECHHHHHHC
GGQALPLICDIRDEAQVIAAIDKTVAEFGGIDICVNNASAISLTNSQATDMKRYDLMMGI
CCCCCEEEEECCCCHHHHHHHHHHHHHHCCEEEEECCCCEEEECCCCCCCHHHEEEEEEC
NSRGTFMVSKYCIPHLKKAANPHILMLSPPLDMKAKWFAASTAYTMAKFGMSMVVLGLSG
CCCCCEEEEHHHHHHHHHCCCCEEEEECCCCCCCEEEEEHHHHHHHHHCCCEEEEEECCC
ELKGAGIAVNALWPRTTIATAAVGNLLGGDAMMRASRTPEIMGDAAHAILTKPSRDFTGQ
CCCCCCEEEEEECCCHHHHHHHHHHHHCCHHHHHCCCCCHHHCCHHHHEEECCCCCCCCE
FCIDDKVLYEAGVTDFERYRVDPSVPLMSDFFVPDDDVPPPGVTVASLPGAKG
EEECCEEEECCCCCCHHHEECCCCCCCHHCCCCCCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]