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The map label for this gene is aroF [H]

Identifier: 86608876

GI number: 86608876

Start: 1475732

End: 1476802

Strand: Direct

Name: aroF [H]

Synonym: CYB_1407

Alternate gene names: 86608876

Gene position: 1475732-1476802 (Clockwise)

Preceding gene: 86608875

Following gene: 86608877

Centisome position: 48.44

GC content: 61.53

Gene sequence:

>1071_bases
ATGCCCCCTCAAACCGACAATTGCAATATCCAAGAGGTGACTCCCTTGATTGCCCCTGCTGCTGTCAAGGCCAAGCTGCC
CCTTACGGAAACGGCAGCCCAGGTGGTGCTCTCCACTCGGCAAGCCATCCGCGACATCATCCACGGACGGGATCTCCATC
GCTTGGTGGTGATCGTCGGCCCCTGTTCCATCCACGATCCCGCAGCGGCTCTGGAGTATGCCCATCGCCTCAAGCGGGTG
GCCGACCAAACTCGGGAGCACCTAGTGGTTGTCATGCGTACGTATTTTGAGAAACCCCGCACCACGGTGGGCTGGAAGGG
CCTGATCAACGATCCCCACCTGGATGGCTCCTGCGACATTGCCACCGGCCTGCAACTGGCCCGTTCCATTCTCTTGCAGA
TCAACGAGCTGGGCCTGGCCTGTGCCACCGAGATGCTGGATCCGGTGACCCCTCAGTACACGGCAGATCTGGTGAGCTGG
GCGGCCATTGGCGCCAGAACCATCGAAAGCCAAACTCACCGGGAAATGGCCAGCGGCCTCTCCATGCCTGTGGGCTTCAA
AAACGGCACCGACGGGCGGCTGGAAATTGCGCTCAATGCCATTCTCTCCGCCAGCCATCCCCACAGTTTCCTGGGCATCG
GCCAAGATGGCATGACGGCTCTGGTGAAAACCACCGGCAACCCGGATCGGCACATCGTGTTGCGGGGGGGAGGGGGCAAG
ACCAACTACGGCCCGGAAGATGTGGCGCGGGCGGCACTGCTGATGAAGGATCAAGGGATCCCTCGCTCGGTGATGGTGGA
CTGCTCCCATGACAACTCCCACAAAAATTACCGCAAGCAGGGATCCGTCTGTCGAGCGGTGCTACAGCAGTACCAGGCGG
GGCAGCGGGCTCTGATGGGGCTGATGCTGGAGAGCAACCTCTACCCGGGCAAGCAAACCTGGCAGGAAGGGGCGCCGCTC
CAGTACGGGGTTTCCATCACCGATGGCTGCATCGGCTGGGAAGAGACGGAAGCTCTGTTGTGGGAGATGGCAGCGACCGT
AGAGGGGAGAGCGTTGGCCCTCAGCCATTGA

Upstream 100 bases:

>100_bases
CAGTTTACCCGAGTCAGTCCTGAAGCCCTGAGCCCAGCGCCAGGGCTTTTTTGATGGCTCGACGACCCCATCTACCCACT
TGCACGCTGAGGACAGTTCC

Downstream 100 bases:

>100_bases
GGGATGGGGATCCCGGAGTTTGTTAAAGAATCAAAAAGGAAATGGGGACAAGGGGCAGCCTGCTCCTAGGGTCGAGCCAA
GGTTTCGTTGTTTCGCCAGG

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MPPQTDNCNIQEVTPLIAPAAVKAKLPLTETAAQVVLSTRQAIRDIIHGRDLHRLVVIVGPCSIHDPAAALEYAHRLKRV
ADQTREHLVVVMRTYFEKPRTTVGWKGLINDPHLDGSCDIATGLQLARSILLQINELGLACATEMLDPVTPQYTADLVSW
AAIGARTIESQTHREMASGLSMPVGFKNGTDGRLEIALNAILSASHPHSFLGIGQDGMTALVKTTGNPDRHIVLRGGGGK
TNYGPEDVARAALLMKDQGIPRSVMVDCSHDNSHKNYRKQGSVCRAVLQQYQAGQRALMGLMLESNLYPGKQTWQEGAPL
QYGVSITDGCIGWEETEALLWEMAATVEGRALALSH

Sequences:

>Translated_356_residues
MPPQTDNCNIQEVTPLIAPAAVKAKLPLTETAAQVVLSTRQAIRDIIHGRDLHRLVVIVGPCSIHDPAAALEYAHRLKRV
ADQTREHLVVVMRTYFEKPRTTVGWKGLINDPHLDGSCDIATGLQLARSILLQINELGLACATEMLDPVTPQYTADLVSW
AAIGARTIESQTHREMASGLSMPVGFKNGTDGRLEIALNAILSASHPHSFLGIGQDGMTALVKTTGNPDRHIVLRGGGGK
TNYGPEDVARAALLMKDQGIPRSVMVDCSHDNSHKNYRKQGSVCRAVLQQYQAGQRALMGLMLESNLYPGKQTWQEGAPL
QYGVSITDGCIGWEETEALLWEMAATVEGRALALSH
>Mature_355_residues
PPQTDNCNIQEVTPLIAPAAVKAKLPLTETAAQVVLSTRQAIRDIIHGRDLHRLVVIVGPCSIHDPAAALEYAHRLKRVA
DQTREHLVVVMRTYFEKPRTTVGWKGLINDPHLDGSCDIATGLQLARSILLQINELGLACATEMLDPVTPQYTADLVSWA
AIGARTIESQTHREMASGLSMPVGFKNGTDGRLEIALNAILSASHPHSFLGIGQDGMTALVKTTGNPDRHIVLRGGGGKT
NYGPEDVARAALLMKDQGIPRSVMVDCSHDNSHKNYRKQGSVCRAVLQQYQAGQRALMGLMLESNLYPGKQTWQEGAPLQ
YGVSITDGCIGWEETEALLWEMAATVEGRALALSH

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=349, Percent_Identity=54.4412607449857, Blast_Score=391, Evalue=1e-110,
Organism=Escherichia coli, GI1786969, Length=350, Percent_Identity=53.4285714285714, Blast_Score=381, Evalue=1e-107,
Organism=Escherichia coli, GI1787996, Length=347, Percent_Identity=49.8559077809798, Blast_Score=340, Evalue=7e-95,
Organism=Saccharomyces cerevisiae, GI6319726, Length=340, Percent_Identity=49.7058823529412, Blast_Score=328, Evalue=8e-91,
Organism=Saccharomyces cerevisiae, GI6320240, Length=352, Percent_Identity=43.75, Blast_Score=324, Evalue=2e-89,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38631; Mature: 38500

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPQTDNCNIQEVTPLIAPAAVKAKLPLTETAAQVVLSTRQAIRDIIHGRDLHRLVVIVG
CCCCCCCCCHHHHHHHHCCHHHEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEE
PCSIHDPAAALEYAHRLKRVADQTREHLVVVMRTYFEKPRTTVGWKGLINDPHLDGSCDI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCH
ATGLQLARSILLQINELGLACATEMLDPVTPQYTADLVSWAAIGARTIESQTHREMASGL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SMPVGFKNGTDGRLEIALNAILSASHPHSFLGIGQDGMTALVKTTGNPDRHIVLRGGGGK
CCCCCCCCCCCCEEEHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCCEEEEECCCCC
TNYGPEDVARAALLMKDQGIPRSVMVDCSHDNSHKNYRKQGSVCRAVLQQYQAGQRALMG
CCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMLESNLYPGKQTWQEGAPLQYGVSITDGCIGWEETEALLWEMAATVEGRALALSH
HHHHCCCCCCHHHHHCCCCEEECCEECCCCCCHHHHHHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure 
PPQTDNCNIQEVTPLIAPAAVKAKLPLTETAAQVVLSTRQAIRDIIHGRDLHRLVVIVG
CCCCCCCCHHHHHHHHCCHHHEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEE
PCSIHDPAAALEYAHRLKRVADQTREHLVVVMRTYFEKPRTTVGWKGLINDPHLDGSCDI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCH
ATGLQLARSILLQINELGLACATEMLDPVTPQYTADLVSWAAIGARTIESQTHREMASGL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SMPVGFKNGTDGRLEIALNAILSASHPHSFLGIGQDGMTALVKTTGNPDRHIVLRGGGGK
CCCCCCCCCCCCEEEHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCCEEEEECCCCC
TNYGPEDVARAALLMKDQGIPRSVMVDCSHDNSHKNYRKQGSVCRAVLQQYQAGQRALMG
CCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMLESNLYPGKQTWQEGAPLQYGVSITDGCIGWEETEALLWEMAATVEGRALALSH
HHHHCCCCCCHHHHHCCCCEEECCEECCCCCCHHHHHHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]