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The map label for this gene is holB [H]

Identifier: 86608578

GI number: 86608578

Start: 1134770

End: 1135801

Strand: Reverse

Name: holB [H]

Synonym: CYB_1099

Alternate gene names: 86608578

Gene position: 1135801-1134770 (Counterclockwise)

Preceding gene: 86608580

Following gene: 86608575

Centisome position: 37.28

GC content: 63.86

Gene sequence:

>1032_bases
TTGCCTCCACAGCACATTGTCGGGCAGGAGATGGCGGCACGACTGCTTGTGGCGGCCCTGGAGAAGGAGCGGGTGACTTC
CAGCTACTGCTTCTTGGGCCCCCAAGGGGTGGGGCGGAAGCTGATGGCCCGTTGGTTTGCCCAGGCCCTCTTGTGCGAAT
CCAGCTCCGGGATCCCTTGCGGCAAGTGCTCCCACTGCCGTTGGCTGCTGGCGGGCAACCATCCCGATCTCCACTGGGTC
AGCCCCACCTACCTGCACCAAGGCCGCCTAATTGCGGCAGACTCCCCGGAGGCGCAAACCTTGCAACGGCGCTCGCCGCC
CCAAATTCGCCTGGAGCAGGTGCAGGGGGTATCCCGCTTCTGTGCCCGCAAGCCGATTCGAGCCCAGCGAAAGGGCTCCG
CCCCGCTAAAGGACTCCGTCCCGCTTACGCGAACGGGAGCGGTGGTGGTGCTGGAGGGAGCCGAAACCTTGGCGGAAAGC
GCTGCCAATGCTTTGTTGAAAACCCTGGAGGAGCCAGGCCCAGCCCATATTATACTCATCGCCCCCCAGGCGGCCTCGCT
GTTGCCGACGCTGTTGTCCCGCTGCCAGATGGTGCCTTTTCGCCGCCTCAGCCCAGAAGAGGTCGACCGGGTGCTGAGTG
GGTTGGGTTGCCCAGATCTGGCAGGGATCCCTCGATCCGAGCTGATTGCCTTGGCCCAGGGCAGCCCCGGCTTGGCCTTG
CTGGCCCACCAGCACCTGCAGCAGATCCCGCCGTCGCTCCTTGAGGAACTCAAACGTTGGCCCTGGCACTCTTCTCTCCA
GCAGGCATTGGAATTGGGCAGAGCGGTGGCCAGTTTGGAGCTGCCGGCACAACTGTGGCTGATCGATTATTTGCAGCAGC
ATTTTTGGGCGCAGGGATCCCGTCAGCCGTTTGCGCCAGGGGTGCAGAGCGCCATCCGGCAGTTGGAACGCATTCGCCAA
CACCTGTTGCAACTGGTGCAGCCCCGTCTCTGTTGGGAGGTCAACCTTGCCAGCATTAGCCCGGGTGGGTGA

Upstream 100 bases:

>100_bases
GCAGTATTTTCGCAAACATTTCCTGCCAGCTTCTGCCAGCGGATGCTGAGATATGCCAGAACTCCGTCCGAGCGCCGAGA
CCGTCAAGCGGATGAAGGTC

Downstream 100 bases:

>100_bases
TGTGGTAGCTGCCGTCGGCTTGTACCCAGGCGATCTCCGGGATCCGACATTGGCGGGCATAGGCTTCGATCTCTTCAGGG
GCCCGATCCAGCAATTCCAG

Product: DNA polymerase III subunit delta'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MPPQHIVGQEMAARLLVAALEKERVTSSYCFLGPQGVGRKLMARWFAQALLCESSSGIPCGKCSHCRWLLAGNHPDLHWV
SPTYLHQGRLIAADSPEAQTLQRRSPPQIRLEQVQGVSRFCARKPIRAQRKGSAPLKDSVPLTRTGAVVVLEGAETLAES
AANALLKTLEEPGPAHIILIAPQAASLLPTLLSRCQMVPFRRLSPEEVDRVLSGLGCPDLAGIPRSELIALAQGSPGLAL
LAHQHLQQIPPSLLEELKRWPWHSSLQQALELGRAVASLELPAQLWLIDYLQQHFWAQGSRQPFAPGVQSAIRQLERIRQ
HLLQLVQPRLCWEVNLASISPGG

Sequences:

>Translated_343_residues
MPPQHIVGQEMAARLLVAALEKERVTSSYCFLGPQGVGRKLMARWFAQALLCESSSGIPCGKCSHCRWLLAGNHPDLHWV
SPTYLHQGRLIAADSPEAQTLQRRSPPQIRLEQVQGVSRFCARKPIRAQRKGSAPLKDSVPLTRTGAVVVLEGAETLAES
AANALLKTLEEPGPAHIILIAPQAASLLPTLLSRCQMVPFRRLSPEEVDRVLSGLGCPDLAGIPRSELIALAQGSPGLAL
LAHQHLQQIPPSLLEELKRWPWHSSLQQALELGRAVASLELPAQLWLIDYLQQHFWAQGSRQPFAPGVQSAIRQLERIRQ
HLLQLVQPRLCWEVNLASISPGG
>Mature_342_residues
PPQHIVGQEMAARLLVAALEKERVTSSYCFLGPQGVGRKLMARWFAQALLCESSSGIPCGKCSHCRWLLAGNHPDLHWVS
PTYLHQGRLIAADSPEAQTLQRRSPPQIRLEQVQGVSRFCARKPIRAQRKGSAPLKDSVPLTRTGAVVVLEGAETLAESA
ANALLKTLEEPGPAHIILIAPQAASLLPTLLSRCQMVPFRRLSPEEVDRVLSGLGCPDLAGIPRSELIALAQGSPGLALL
AHQHLQQIPPSLLEELKRWPWHSSLQQALELGRAVASLELPAQLWLIDYLQQHFWAQGSRQPFAPGVQSAIRQLERIRQH
LLQLVQPRLCWEVNLASISPGG

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004622 [H]

Pfam domain/function: NA

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 37657; Mature: 37526

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPQHIVGQEMAARLLVAALEKERVTSSYCFLGPQGVGRKLMARWFAQALLCESSSGIPC
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCC
GKCSHCRWLLAGNHPDLHWVSPTYLHQGRLIAADSPEAQTLQRRSPPQIRLEQVQGVSRF
CCCCCCEEEEECCCCCCEECCHHHHHCCEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHH
CARKPIRAQRKGSAPLKDSVPLTRTGAVVVLEGAETLAESAANALLKTLEEPGPAHIILI
HHCCCCHHHCCCCCCCCCCCCCEECCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEE
APQAASLLPTLLSRCQMVPFRRLSPEEVDRVLSGLGCPDLAGIPRSELIALAQGSPGLAL
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHEEEEECCCCCHHH
LAHQHLQQIPPSLLEELKRWPWHSSLQQALELGRAVASLELPAQLWLIDYLQQHFWAQGS
HHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
RQPFAPGVQSAIRQLERIRQHLLQLVQPRLCWEVNLASISPGG
CCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCC
>Mature Secondary Structure 
PPQHIVGQEMAARLLVAALEKERVTSSYCFLGPQGVGRKLMARWFAQALLCESSSGIPC
CCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCC
GKCSHCRWLLAGNHPDLHWVSPTYLHQGRLIAADSPEAQTLQRRSPPQIRLEQVQGVSRF
CCCCCCEEEEECCCCCCEECCHHHHHCCEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHH
CARKPIRAQRKGSAPLKDSVPLTRTGAVVVLEGAETLAESAANALLKTLEEPGPAHIILI
HHCCCCHHHCCCCCCCCCCCCCEECCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEE
APQAASLLPTLLSRCQMVPFRRLSPEEVDRVLSGLGCPDLAGIPRSELIALAQGSPGLAL
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHEEEEECCCCCHHH
LAHQHLQQIPPSLLEELKRWPWHSSLQQALELGRAVASLELPAQLWLIDYLQQHFWAQGS
HHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
RQPFAPGVQSAIRQLERIRQHLLQLVQPRLCWEVNLASISPGG
CCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]