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The map label for this gene is ubiB [C]

Identifier: 86608544

GI number: 86608544

Start: 1103050

End: 1104822

Strand: Reverse

Name: ubiB [C]

Synonym: CYB_1066

Alternate gene names: 86608544

Gene position: 1104822-1103050 (Counterclockwise)

Preceding gene: 86608545

Following gene: 86608543

Centisome position: 36.26

GC content: 57.47

Gene sequence:

>1773_bases
GTGTTTAGTAGAACTTCGCCCATTGCCGCTTTGGAAGTTTACGATCCGCAATTGATCTGCCGCTATTACCGCTGGCGCCT
GCCCCAAGTGATCGGTCGGGCGCTGGCCATTCTCTGGCCTTTCTTGTGGTTTGTCCTCTGTTTGCGCTGGGATCAACTGT
GGGGACACACTGATCGCAATGTGGGACGGCGCTCGGTGCAGTTGCGAAAGCTGCTCACCGACCTGGGGCCAACGTTCATC
AAGGTGGGTCAGGCCCTCTCCACCCGCCCCGATCTGGTGCGCAAAGACTACCTAGAAGAACTCACCCAACTGCAAGATCA
ACTGCCGCCATTTCCTTCCGAGCAAGCATTTGCCCGCATCGAATCCGAGTTGGGCCGTCCGATTGCCGAGATCTTTGCCC
AGATCTCTCCAGAGCCGGTGGCTGCTGCCAGCCTGGGGCAGGTCTACAAAGCGCAGTTGCACAGCGGCGAATGGGTGGCG
GTGAAGGTGCAGCGACCCCATCTGCGAGAGCAGTTGAGCCTGGATCTGTACCTGATTCGCTGGGCCTCGACATGGCTGGG
CCCCTGGCTGCCCTTAAACCTGGGCAGTACTTTGACGGCGGTGGTGGATGAGTTTGGCCGCAAGCTTTTTGAAGAGATCG
ACTACCTGCACGAAGGGCGAAACTGCGAGCGCTTCGCCGAATACTTCCGCGACGATCCGGATGTGTACGTGCCGCGCATC
TTTTGGGCTTACAGCACCCGCCGGGTTCTGACCCTGGAGTGGATCGACGGCATCAAGCTGACGGATGTGGAGCGCATTCG
AGCAGCCAACCTGGAAGTGAAACAATTGGTGCGCATCGGGGTGGTTGCTGCCCTCAAGCAATTGCTGGAATACGGCTTTT
TCCACGCGGATCCCCATCCAGGTAACTTGTTTGCCCTCACCGATGGCCGTATGGCCTACATCGATTTCGGCATGATGGAT
CAGCTTACCGAGGAAATGAAGGAGTACTTGGTGGATGCTCTGGTTCACCTGGTGGATCGCGACTACAACGCCCTGATCGA
TGACTTTATTCATCTGGGCTTTTTGCAGCCGGATGTCGGCCGCCAAGAGCTGATCCCCGCCTTGGAAAAGGTGCTGGCAG
ACGTGCTGACCCAAGAGGTGGTCAACTTTAACTTCAAAACGGCCACAGATCAGTTCTCCGACTTGATGTACCGCTACCCC
TTTCAGGTGCCCTCCCACTTTGCTCTGGTGATCCGATCTTTGGTGACCCAAGAGGGAGTAGCCCTCAGCCTCTATCCCCA
GTTCCGCATCGTCGGTGTGGCCTATCCCTATGTGGCCAAGCGCCTGCTGACGGATGAATCGCCGCGTATTCGCCAACGGC
TGCTGCAAGTGTTGATCAAGGATGGTAAGTTCCGCTGGAACCGCCTGGAGAACCTGATTCAAATTGCCCGCAGCGATGGG
GGATTGGATTGGTTACCCACTGCCCAAACGGGTTTGCGCTACCTGATGTCGGAAGAGGCCCGCGATCTGCGTCGCCAGTT
GGTGCTTTCCCTCACAGAAGATGATCGCCTTCACTTTGAGGAGCTGCAGCGTTTGTGGCAGTTGCTCAGCCCTGAACTTT
CCCCAGCTTACCTCTGGCAGGCAACGCTGAGATCCCTACCCTCGACCGGCGATCTGCAACACACGCTTGTCGAGTTGAGG
GAGCAGGTGCAAGCCCATCTGGAACATCTCAGCCGCTGGCGGCTACCTCAACCTTGGTCGGATTTGCTGGCAGGAGTGGG
ACAGGAAAGGTAG

Upstream 100 bases:

>100_bases
AGGATGGGGCTGACAGGCCCTTGCGCAGAAACGGCGAGGCTTTTTCTGTTAAGATGGATACCAAGAGCTTCAAAACAAAA
AACTGTGAGATCGCTGGAGT

Downstream 100 bases:

>100_bases
AACGGAAGAAGATGACTCAAGTTTATTGTTATTGAGCTGGACAAAAGCGTGGCAGATCAGAAAGGTGACTTCATTGCGGG
TGTAGTGACTGGCGCCCTGT

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 590; Mature: 590

Protein sequence:

>590_residues
MFSRTSPIAALEVYDPQLICRYYRWRLPQVIGRALAILWPFLWFVLCLRWDQLWGHTDRNVGRRSVQLRKLLTDLGPTFI
KVGQALSTRPDLVRKDYLEELTQLQDQLPPFPSEQAFARIESELGRPIAEIFAQISPEPVAAASLGQVYKAQLHSGEWVA
VKVQRPHLREQLSLDLYLIRWASTWLGPWLPLNLGSTLTAVVDEFGRKLFEEIDYLHEGRNCERFAEYFRDDPDVYVPRI
FWAYSTRRVLTLEWIDGIKLTDVERIRAANLEVKQLVRIGVVAALKQLLEYGFFHADPHPGNLFALTDGRMAYIDFGMMD
QLTEEMKEYLVDALVHLVDRDYNALIDDFIHLGFLQPDVGRQELIPALEKVLADVLTQEVVNFNFKTATDQFSDLMYRYP
FQVPSHFALVIRSLVTQEGVALSLYPQFRIVGVAYPYVAKRLLTDESPRIRQRLLQVLIKDGKFRWNRLENLIQIARSDG
GLDWLPTAQTGLRYLMSEEARDLRRQLVLSLTEDDRLHFEELQRLWQLLSPELSPAYLWQATLRSLPSTGDLQHTLVELR
EQVQAHLEHLSRWRLPQPWSDLLAGVGQER

Sequences:

>Translated_590_residues
MFSRTSPIAALEVYDPQLICRYYRWRLPQVIGRALAILWPFLWFVLCLRWDQLWGHTDRNVGRRSVQLRKLLTDLGPTFI
KVGQALSTRPDLVRKDYLEELTQLQDQLPPFPSEQAFARIESELGRPIAEIFAQISPEPVAAASLGQVYKAQLHSGEWVA
VKVQRPHLREQLSLDLYLIRWASTWLGPWLPLNLGSTLTAVVDEFGRKLFEEIDYLHEGRNCERFAEYFRDDPDVYVPRI
FWAYSTRRVLTLEWIDGIKLTDVERIRAANLEVKQLVRIGVVAALKQLLEYGFFHADPHPGNLFALTDGRMAYIDFGMMD
QLTEEMKEYLVDALVHLVDRDYNALIDDFIHLGFLQPDVGRQELIPALEKVLADVLTQEVVNFNFKTATDQFSDLMYRYP
FQVPSHFALVIRSLVTQEGVALSLYPQFRIVGVAYPYVAKRLLTDESPRIRQRLLQVLIKDGKFRWNRLENLIQIARSDG
GLDWLPTAQTGLRYLMSEEARDLRRQLVLSLTEDDRLHFEELQRLWQLLSPELSPAYLWQATLRSLPSTGDLQHTLVELR
EQVQAHLEHLSRWRLPQPWSDLLAGVGQER
>Mature_590_residues
MFSRTSPIAALEVYDPQLICRYYRWRLPQVIGRALAILWPFLWFVLCLRWDQLWGHTDRNVGRRSVQLRKLLTDLGPTFI
KVGQALSTRPDLVRKDYLEELTQLQDQLPPFPSEQAFARIESELGRPIAEIFAQISPEPVAAASLGQVYKAQLHSGEWVA
VKVQRPHLREQLSLDLYLIRWASTWLGPWLPLNLGSTLTAVVDEFGRKLFEEIDYLHEGRNCERFAEYFRDDPDVYVPRI
FWAYSTRRVLTLEWIDGIKLTDVERIRAANLEVKQLVRIGVVAALKQLLEYGFFHADPHPGNLFALTDGRMAYIDFGMMD
QLTEEMKEYLVDALVHLVDRDYNALIDDFIHLGFLQPDVGRQELIPALEKVLADVLTQEVVNFNFKTATDQFSDLMYRYP
FQVPSHFALVIRSLVTQEGVALSLYPQFRIVGVAYPYVAKRLLTDESPRIRQRLLQVLIKDGKFRWNRLENLIQIARSDG
GLDWLPTAQTGLRYLMSEEARDLRRQLVLSLTEDDRLHFEELQRLWQLLSPELSPAYLWQATLRSLPSTGDLQHTLVELR
EQVQAHLEHLSRWRLPQPWSDLLAGVGQER

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=270, Percent_Identity=33.3333333333333, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI41393593, Length=357, Percent_Identity=28.5714285714286, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI217035081, Length=260, Percent_Identity=32.3076923076923, Blast_Score=127, Evalue=4e-29,
Organism=Homo sapiens, GI27363457, Length=278, Percent_Identity=26.2589928057554, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI34147522, Length=279, Percent_Identity=26.1648745519713, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI217416386, Length=237, Percent_Identity=26.1603375527426, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI32261307, Length=312, Percent_Identity=23.0769230769231, Blast_Score=74, Evalue=6e-13,
Organism=Escherichia coli, GI2367309, Length=389, Percent_Identity=31.1053984575836, Blast_Score=189, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17559152, Length=280, Percent_Identity=31.7857142857143, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI32565180, Length=288, Percent_Identity=30.2083333333333, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17555620, Length=292, Percent_Identity=22.9452054794521, Blast_Score=66, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323282, Length=241, Percent_Identity=28.6307053941909, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321319, Length=307, Percent_Identity=28.0130293159609, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6325148, Length=314, Percent_Identity=26.4331210191083, Blast_Score=100, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24662575, Length=363, Percent_Identity=31.129476584022, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI22024280, Length=266, Percent_Identity=31.9548872180451, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI18859849, Length=282, Percent_Identity=26.5957446808511, Blast_Score=79, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 68584; Mature: 68584

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSRTSPIAALEVYDPQLICRYYRWRLPQVIGRALAILWPFLWFVLCLRWDQLWGHTDRN
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VGRRSVQLRKLLTDLGPTFIKVGQALSTRPDLVRKDYLEELTQLQDQLPPFPSEQAFARI
HHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ESELGRPIAEIFAQISPEPVAAASLGQVYKAQLHSGEWVAVKVQRPHLREQLSLDLYLIR
HHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHCHHHHHHH
WASTWLGPWLPLNLGSTLTAVVDEFGRKLFEEIDYLHEGRNCERFAEYFRDDPDVYVPRI
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEHHHH
FWAYSTRRVLTLEWIDGIKLTDVERIRAANLEVKQLVRIGVVAALKQLLEYGFFHADPHP
HEEECCCEEEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GNLFALTDGRMAYIDFGMMDQLTEEMKEYLVDALVHLVDRDYNALIDDFIHLGFLQPDVG
CCEEEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCC
RQELIPALEKVLADVLTQEVVNFNFKTATDQFSDLMYRYPFQVPSHFALVIRSLVTQEGV
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
ALSLYPQFRIVGVAYPYVAKRLLTDESPRIRQRLLQVLIKDGKFRWNRLENLIQIARSDG
EEEECCCEEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
GLDWLPTAQTGLRYLMSEEARDLRRQLVLSLTEDDRLHFEELQRLWQLLSPELSPAYLWQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
ATLRSLPSTGDLQHTLVELREQVQAHLEHLSRWRLPQPWSDLLAGVGQER
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCC
>Mature Secondary Structure
MFSRTSPIAALEVYDPQLICRYYRWRLPQVIGRALAILWPFLWFVLCLRWDQLWGHTDRN
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VGRRSVQLRKLLTDLGPTFIKVGQALSTRPDLVRKDYLEELTQLQDQLPPFPSEQAFARI
HHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ESELGRPIAEIFAQISPEPVAAASLGQVYKAQLHSGEWVAVKVQRPHLREQLSLDLYLIR
HHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHCHHHHHHH
WASTWLGPWLPLNLGSTLTAVVDEFGRKLFEEIDYLHEGRNCERFAEYFRDDPDVYVPRI
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEHHHH
FWAYSTRRVLTLEWIDGIKLTDVERIRAANLEVKQLVRIGVVAALKQLLEYGFFHADPHP
HEEECCCEEEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GNLFALTDGRMAYIDFGMMDQLTEEMKEYLVDALVHLVDRDYNALIDDFIHLGFLQPDVG
CCEEEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCC
RQELIPALEKVLADVLTQEVVNFNFKTATDQFSDLMYRYPFQVPSHFALVIRSLVTQEGV
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
ALSLYPQFRIVGVAYPYVAKRLLTDESPRIRQRLLQVLIKDGKFRWNRLENLIQIARSDG
EEEECCCEEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
GLDWLPTAQTGLRYLMSEEARDLRRQLVLSLTEDDRLHFEELQRLWQLLSPELSPAYLWQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
ATLRSLPSTGDLQHTLVELREQVQAHLEHLSRWRLPQPWSDLLAGVGQER
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]