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The map label for this gene is murQ

Identifier: 86608497

GI number: 86608497

Start: 1057548

End: 1058462

Strand: Reverse

Name: murQ

Synonym: CYB_1018

Alternate gene names: 86608497

Gene position: 1058462-1057548 (Counterclockwise)

Preceding gene: 86608498

Following gene: 86608496

Centisome position: 34.74

GC content: 61.75

Gene sequence:

>915_bases
TTGGCTTGGGATCCCAGATCCCTGACCGAAAGCCCCAACCCGGCTACAGCCGAGATCGACCGTCTCAGCACCTGGGAACT
GGTGAAACGGATCAACGCCGAGGATCGGCAGGTGCCGGAAGCGGTGGCTGCTCAGGCGGAGCCGATTGCCCAAGCCATCG
ATGCCATTGCCCAGCGGATGCGTCACGGCGGGCGGCTGATCTATATCGGGGCAGGAACCTCAGGTCGGCTGGGGGTACTG
GATGCGGCTGAGTGCCCACCCACTTTTGGCACTTCCCCCGCACAGGTGGTGGCTTTGATCGCCGGGGGGGAAAAAGCCCT
GACCCAGGCGGTAGAGGGTGCAGAGGACGACGCAGAAGCGGCTGCCCGCGCGCTGGAGGGTCTTCACCTCCAAGCTCAAG
ATAGTGTTGTGGGAATTGCCGCCAGCGGTCGTACCCCCTATGTGCTGGGTGGGATCCAAGCCGCCAGAAGTATTGGGGCG
CTCACGATTGGCCTGGCCTGCAATCACCCTTCTCCTCTAACCGAGCAGGTGGATATTGCTATTGCCCCTTTGGTGGGGCC
GGAGGTAATCCTCGGATCCACCCGCATGAAAGCCGGCACAGCCCAAAAGTTGGTGTTGAACACGATCTCCACCGGGGTGA
TGATCCGCTTGGGCAAGACTTATGGCAACCTAATGGTGGATCTCCAGGCCAGCAATGCCAAGCTCAAGCAGCGGGCGGAG
CGAATGGTGGCCCTAGCCTGCGATCTGGATCCCGCCGCGGCTGCCCAATTGCTGCAGGCTTGTGATGGAGAGGTGAAAAC
CGCGATCCTTGTGGCCTTGATGGGGTGCTCTGCTCAGGAAGCTCGTCAGCACTTGCAACAGGCCCAGGGCAACATTCGCC
AGGTGCTTGATTCCGTTCTGGCGCAGCGGCGGTGA

Upstream 100 bases:

>100_bases
AGAGCCCCCTGCCACCGATAGAATCCGAGAAGACAAAGTGTAGGATCCCTGAAGGCGGATCCCTCTTGCCTGGACAAGCG
CTGCCATGGTTTCTCCACAA

Downstream 100 bases:

>100_bases
CAATAGTTGAATGGCTTGTCCATGAGCGTTTGCGGCTACCTCTACACGCCTTCCCATGCCCCTTTGCCGGAACAGGAGTT
GGCCTGGCTCAAGTTGCGAG

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MAWDPRSLTESPNPATAEIDRLSTWELVKRINAEDRQVPEAVAAQAEPIAQAIDAIAQRMRHGGRLIYIGAGTSGRLGVL
DAAECPPTFGTSPAQVVALIAGGEKALTQAVEGAEDDAEAAARALEGLHLQAQDSVVGIAASGRTPYVLGGIQAARSIGA
LTIGLACNHPSPLTEQVDIAIAPLVGPEVILGSTRMKAGTAQKLVLNTISTGVMIRLGKTYGNLMVDLQASNAKLKQRAE
RMVALACDLDPAAAAQLLQACDGEVKTAILVALMGCSAQEARQHLQQAQGNIRQVLDSVLAQRR

Sequences:

>Translated_304_residues
MAWDPRSLTESPNPATAEIDRLSTWELVKRINAEDRQVPEAVAAQAEPIAQAIDAIAQRMRHGGRLIYIGAGTSGRLGVL
DAAECPPTFGTSPAQVVALIAGGEKALTQAVEGAEDDAEAAARALEGLHLQAQDSVVGIAASGRTPYVLGGIQAARSIGA
LTIGLACNHPSPLTEQVDIAIAPLVGPEVILGSTRMKAGTAQKLVLNTISTGVMIRLGKTYGNLMVDLQASNAKLKQRAE
RMVALACDLDPAAAAQLLQACDGEVKTAILVALMGCSAQEARQHLQQAQGNIRQVLDSVLAQRR
>Mature_303_residues
AWDPRSLTESPNPATAEIDRLSTWELVKRINAEDRQVPEAVAAQAEPIAQAIDAIAQRMRHGGRLIYIGAGTSGRLGVLD
AAECPPTFGTSPAQVVALIAGGEKALTQAVEGAEDDAEAAARALEGLHLQAQDSVVGIAASGRTPYVLGGIQAARSIGAL
TIGLACNHPSPLTEQVDIAIAPLVGPEVILGSTRMKAGTAQKLVLNTISTGVMIRLGKTYGNLMVDLQASNAKLKQRAER
MVALACDLDPAAAAQLLQACDGEVKTAILVALMGCSAQEARQHLQQAQGNIRQVLDSVLAQRR

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1788768, Length=294, Percent_Identity=54.7619047619048, Blast_Score=303, Evalue=7e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURQ_SYNJB (Q2JMP1)

Other databases:

- EMBL:   CP000240
- RefSeq:   YP_477259.1
- ProteinModelPortal:   Q2JMP1
- SMR:   Q2JMP1
- STRING:   Q2JMP1
- GeneID:   3902161
- GenomeReviews:   CP000240_GR
- KEGG:   cyb:CYB_1018
- TIGR:   CYB_1018
- eggNOG:   COG2103
- HOGENOM:   HBG703490
- OMA:   LVPTYGI
- PhylomeDB:   Q2JMP1
- ProtClustDB:   PRK05441
- BioCyc:   SSP321332:CYB_1018-MONOMER
- HAMAP:   MF_00068
- InterPro:   IPR005488
- InterPro:   IPR001347
- TIGRFAMs:   TIGR00274

Pfam domain/function: PF01380 SIS

EC number: NA

Molecular weight: Translated: 31727; Mature: 31596

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS01272 GCKR; PS51464 SIS

Important sites: ACT_SITE 84-84 ACT_SITE 115-115

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWDPRSLTESPNPATAEIDRLSTWELVKRINAEDRQVPEAVAAQAEPIAQAIDAIAQRM
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RHGGRLIYIGAGTSGRLGVLDAAECPPTFGTSPAQVVALIAGGEKALTQAVEGAEDDAEA
HHCCEEEEEECCCCCCEEECCCCCCCCCCCCCHHHEEEEEECCHHHHHHHHCCCCCHHHH
AARALEGLHLQAQDSVVGIAASGRTPYVLGGIQAARSIGALTIGLACNHPSPLTEQVDIA
HHHHHHCCCEEECCCEEEEEECCCCCEEEHHHHHHHHHCCEEEEEEECCCCCCCCCCCEE
IAPLVGPEVILGSTRMKAGTAQKLVLNTISTGVMIRLGKTYGNLMVDLQASNAKLKQRAE
EECCCCCHHEECCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCHHHHHHHH
RMVALACDLDPAAAAQLLQACDGEVKTAILVALMGCSAQEARQHLQQAQGNIRQVLDSVL
HHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AQRR
HCCC
>Mature Secondary Structure 
AWDPRSLTESPNPATAEIDRLSTWELVKRINAEDRQVPEAVAAQAEPIAQAIDAIAQRM
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RHGGRLIYIGAGTSGRLGVLDAAECPPTFGTSPAQVVALIAGGEKALTQAVEGAEDDAEA
HHCCEEEEEECCCCCCEEECCCCCCCCCCCCCHHHEEEEEECCHHHHHHHHCCCCCHHHH
AARALEGLHLQAQDSVVGIAASGRTPYVLGGIQAARSIGALTIGLACNHPSPLTEQVDIA
HHHHHHCCCEEECCCEEEEEECCCCCEEEHHHHHHHHHCCEEEEEEECCCCCCCCCCCEE
IAPLVGPEVILGSTRMKAGTAQKLVLNTISTGVMIRLGKTYGNLMVDLQASNAKLKQRAE
EECCCCCHHEECCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCHHHHHHHH
RMVALACDLDPAAAAQLLQACDGEVKTAILVALMGCSAQEARQHLQQAQGNIRQVLDSVL
HHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AQRR
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA