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The map label for this gene is htpG [H]

Identifier: 86608481

GI number: 86608481

Start: 1041947

End: 1043806

Strand: Direct

Name: htpG [H]

Synonym: CYB_1003

Alternate gene names: 86608481

Gene position: 1041947-1043806 (Clockwise)

Preceding gene: 86608480

Following gene: 86608483

Centisome position: 34.2

GC content: 52.63

Gene sequence:

>1860_bases
ATGACCGTGCTGGAACAGGGATCCATCACCATCCACACCGAGAACATCTTTCCCATCATCAAGCAGTCTCTCTACTCGGA
TCGAGAGATCTTCTTGCGGGAGCTGATCTCCAATGCTGCTGATGCCATCACCAAGCTGAAGATGGCCAGCCTTGCCGGCG
AAGTGGCAGATCTCCCAGAGCCGGAGATTACGATTGCCCTCAACAAGGAGGCCAAGACCTTAGCGGTGGCCGATAACGGC
ATTGGCATGACTGCCGAGGAAGTGAAAAAATACATCAACCAGGTGGCTTTTTCCAGCGCTGAAGAGTTCATTCAAAAGTA
CAAGGGCAAAGACGCAGAGCAAGCAATCATTGGCCACTTTGGTCTAGGATTCTACTCCTCTTTTATGGTGTCGCAGCGGG
TGGAGATCGACACCCTCTCCTATCGGCCCGGCAGCACGCCGGTGAAGTGGGCTTGTGACGGCACCACTACTTTTACCCTC
TCCGATTCTGAGCGCTCCAGCATCGGCACCACCGTTACCCTTTACATCACCCCCGAAAACGAAGAATACCTGGAGCCAAG
CCGCATTCGGGAATTGGTTCGTAAATACTGCGATTTCATCCCCGTTCCCATCAAGTTAAACGGGGAAGTGATCAACAAGC
AAAAGCCCCTGTGGAGAACCTCACCTTCCGAACTCAAAGATGAGGATTACCTAGAGTTTTATCGCTACCTCTATCCCTTC
CAAGAGGATCCCCATTTCTGGGTGCACATCAACACCGACTATCCCTTCATCGTGCAAGGGATCCTCTATTTCCCCAAATT
GCGCCCCGATATTGATCCCACCAAGGGTCAAGTCAAGCTGTTCTGCAATCAAGTCTTTGTCCAAGATAACTGTGAGGAAG
TCATCCCCAAGTTTCTCCTGCCTCTGCGGGGGGCCATCGACAGCCCGGATATTCCTCTCAACGTCTCCCGCAGCTTCTTA
CAAAATGACCGCACCGTAAGACGCATTGGGGATCACGTTGCCAAAAAGGTGGCGGATCGTCTCAATGAACTGTACAGGGA
AGATTACGAAAAATACGTCAAGGTCTGGCCCGACATCAGCCTCTTTATGAAGTTTGGGGCGATGAACAACGACAAGTTCT
TTGCCCAGATTAAGGATATTCTCATTTTCCGAGTGGCCGGATCCCCTGCTGACAAACCCGAATATGTGACCCTGAAAGCG
TACCTGGAGCGCACCCGCGACAAGCAAAACAAGCGAGTTTACTACGCCACCGATGAGGCTGCCCAGAGTGCCTACATCGA
TCTCCACCGCTCTCAAGGACTGGAAGTGATCATGCTGGATAGCTGGATCGACAGCCACTTCAGCAGCTTTTTGGAGCGGG
AATACAAAGAAGAAGGGATCCAATTTAAGCGGGTGGACTCTGAGCTGGATGAAACGCTGGTGGATAAAGACAAAGCCGCC
GAAATTGTTGACCCGGTCACGCAAAAAACCCGCAGCCAAAAGTTGGTCGATCTCTTCCGACAAGCCCTGGGCAAAGACAA
GTTGCAGATCCAAGCAGAAGCTCTTAAATCAGAGTCGGTTCCGGCCATGATCTTGCTGCCGGAGACGCTGCGGCGCCTAC
AGGAGCTCAACGCCGTCATCCAGCAGAAGCCGCTGGAGTTTCTGGAAGAGCACACGCTGGTTCTGAACACGGCCCATCCC
CTTATCCAAAACCTGCAGTCTCTTGCCGATCAGGGTCGGGATCCCGACTTGGTTCACCTCATCTGCAATCACATCTACGA
TTTGGCTTTGATTACCCAGAAAAGCTTTGACCCGGCAGCCGTGCGGGCCTTTGTGCAGCGTTCCAACGAAGTGCTGACTC
GCCTCACCCGCCCTCAATAG

Upstream 100 bases:

>100_bases
GTTCGGTTGCGAGTGCGGATTTCCGAAAAAGAGCCTGCTTGTCGGGGACTTTTCGGTCTCTGTAGATTAGCACTGAGCTT
GTTTGAGTGCTGAGCCACCT

Downstream 100 bases:

>100_bases
GCAGCGCTGTCCAGGGTAGACTGCAGGGCTTCCGCTCCACCGGGCAGAGACGGACGGGATCCGGCCCCGTTGCCGCTGTG
GCCGTAGCTGCCTTGGAGCA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 619; Mature: 618

Protein sequence:

>619_residues
MTVLEQGSITIHTENIFPIIKQSLYSDREIFLRELISNAADAITKLKMASLAGEVADLPEPEITIALNKEAKTLAVADNG
IGMTAEEVKKYINQVAFSSAEEFIQKYKGKDAEQAIIGHFGLGFYSSFMVSQRVEIDTLSYRPGSTPVKWACDGTTTFTL
SDSERSSIGTTVTLYITPENEEYLEPSRIRELVRKYCDFIPVPIKLNGEVINKQKPLWRTSPSELKDEDYLEFYRYLYPF
QEDPHFWVHINTDYPFIVQGILYFPKLRPDIDPTKGQVKLFCNQVFVQDNCEEVIPKFLLPLRGAIDSPDIPLNVSRSFL
QNDRTVRRIGDHVAKKVADRLNELYREDYEKYVKVWPDISLFMKFGAMNNDKFFAQIKDILIFRVAGSPADKPEYVTLKA
YLERTRDKQNKRVYYATDEAAQSAYIDLHRSQGLEVIMLDSWIDSHFSSFLEREYKEEGIQFKRVDSELDETLVDKDKAA
EIVDPVTQKTRSQKLVDLFRQALGKDKLQIQAEALKSESVPAMILLPETLRRLQELNAVIQQKPLEFLEEHTLVLNTAHP
LIQNLQSLADQGRDPDLVHLICNHIYDLALITQKSFDPAAVRAFVQRSNEVLTRLTRPQ

Sequences:

>Translated_619_residues
MTVLEQGSITIHTENIFPIIKQSLYSDREIFLRELISNAADAITKLKMASLAGEVADLPEPEITIALNKEAKTLAVADNG
IGMTAEEVKKYINQVAFSSAEEFIQKYKGKDAEQAIIGHFGLGFYSSFMVSQRVEIDTLSYRPGSTPVKWACDGTTTFTL
SDSERSSIGTTVTLYITPENEEYLEPSRIRELVRKYCDFIPVPIKLNGEVINKQKPLWRTSPSELKDEDYLEFYRYLYPF
QEDPHFWVHINTDYPFIVQGILYFPKLRPDIDPTKGQVKLFCNQVFVQDNCEEVIPKFLLPLRGAIDSPDIPLNVSRSFL
QNDRTVRRIGDHVAKKVADRLNELYREDYEKYVKVWPDISLFMKFGAMNNDKFFAQIKDILIFRVAGSPADKPEYVTLKA
YLERTRDKQNKRVYYATDEAAQSAYIDLHRSQGLEVIMLDSWIDSHFSSFLEREYKEEGIQFKRVDSELDETLVDKDKAA
EIVDPVTQKTRSQKLVDLFRQALGKDKLQIQAEALKSESVPAMILLPETLRRLQELNAVIQQKPLEFLEEHTLVLNTAHP
LIQNLQSLADQGRDPDLVHLICNHIYDLALITQKSFDPAAVRAFVQRSNEVLTRLTRPQ
>Mature_618_residues
TVLEQGSITIHTENIFPIIKQSLYSDREIFLRELISNAADAITKLKMASLAGEVADLPEPEITIALNKEAKTLAVADNGI
GMTAEEVKKYINQVAFSSAEEFIQKYKGKDAEQAIIGHFGLGFYSSFMVSQRVEIDTLSYRPGSTPVKWACDGTTTFTLS
DSERSSIGTTVTLYITPENEEYLEPSRIRELVRKYCDFIPVPIKLNGEVINKQKPLWRTSPSELKDEDYLEFYRYLYPFQ
EDPHFWVHINTDYPFIVQGILYFPKLRPDIDPTKGQVKLFCNQVFVQDNCEEVIPKFLLPLRGAIDSPDIPLNVSRSFLQ
NDRTVRRIGDHVAKKVADRLNELYREDYEKYVKVWPDISLFMKFGAMNNDKFFAQIKDILIFRVAGSPADKPEYVTLKAY
LERTRDKQNKRVYYATDEAAQSAYIDLHRSQGLEVIMLDSWIDSHFSSFLEREYKEEGIQFKRVDSELDETLVDKDKAAE
IVDPVTQKTRSQKLVDLFRQALGKDKLQIQAEALKSESVPAMILLPETLRRLQELNAVIQQKPLEFLEEHTLVLNTAHPL
IQNLQSLADQGRDPDLVHLICNHIYDLALITQKSFDPAAVRAFVQRSNEVLTRLTRPQ

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=631, Percent_Identity=30.5863708399366, Blast_Score=297, Evalue=3e-80,
Organism=Homo sapiens, GI4507677, Length=666, Percent_Identity=25.8258258258258, Blast_Score=209, Evalue=5e-54,
Organism=Homo sapiens, GI154146191, Length=249, Percent_Identity=32.9317269076305, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI153792590, Length=249, Percent_Identity=32.9317269076305, Blast_Score=136, Evalue=6e-32,
Organism=Homo sapiens, GI20149594, Length=249, Percent_Identity=30.5220883534137, Blast_Score=122, Evalue=7e-28,
Organism=Escherichia coli, GI1786679, Length=636, Percent_Identity=30.3459119496855, Blast_Score=263, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI115535205, Length=627, Percent_Identity=28.3891547049442, Blast_Score=243, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI17542208, Length=615, Percent_Identity=28.4552845528455, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI115535167, Length=411, Percent_Identity=31.1435523114355, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17559162, Length=492, Percent_Identity=29.2682926829268, Blast_Score=217, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6323840, Length=680, Percent_Identity=26.1764705882353, Blast_Score=212, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6325016, Length=684, Percent_Identity=26.3157894736842, Blast_Score=212, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24586016, Length=640, Percent_Identity=27.5, Blast_Score=258, Evalue=6e-69,
Organism=Drosophila melanogaster, GI21357739, Length=638, Percent_Identity=27.4294670846395, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI17647529, Length=415, Percent_Identity=27.2289156626506, Blast_Score=146, Evalue=4e-35,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71070; Mature: 70939

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLEQGSITIHTENIFPIIKQSLYSDREIFLRELISNAADAITKLKMASLAGEVADLPE
CCEEECCCEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PEITIALNKEAKTLAVADNGIGMTAEEVKKYINQVAFSSAEEFIQKYKGKDAEQAIIGHF
CCEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GLGFYSSFMVSQRVEIDTLSYRPGSTPVKWACDGTTTFTLSDSERSSIGTTVTLYITPEN
HHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCEEEEECCCCCCCCCCEEEEEEECCC
EEYLEPSRIRELVRKYCDFIPVPIKLNGEVINKQKPLWRTSPSELKDEDYLEFYRYLYPF
CCCCCHHHHHHHHHHHHCCCCCCEEECCEEECCCCCCCCCCHHHCCCHHHHHHHHHHCCC
QEDPHFWVHINTDYPFIVQGILYFPKLRPDIDPTKGQVKLFCNQVFVQDNCEEVIPKFLL
CCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHH
PLRGAIDSPDIPLNVSRSFLQNDRTVRRIGDHVAKKVADRLNELYREDYEKYVKVWPDIS
HHCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LFMKFGAMNNDKFFAQIKDILIFRVAGSPADKPEYVTLKAYLERTRDKQNKRVYYATDEA
HHHHHCCCCCCHHHHHHHHHHEEEECCCCCCCCCEEEHHHHHHHHHCCCCCEEEEECCHH
AQSAYIDLHRSQGLEVIMLDSWIDSHFSSFLEREYKEEGIQFKRVDSELDETLVDKDKAA
HHHHHHEEHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCHHHH
EIVDPVTQKTRSQKLVDLFRQALGKDKLQIQAEALKSESVPAMILLPETLRRLQELNAVI
HHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHCCCCCEEEECHHHHHHHHHHHHHH
QQKPLEFLEEHTLVLNTAHPLIQNLQSLADQGRDPDLVHLICNHIYDLALITQKSFDPAA
HHHHHHHHHCCCEEEECHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHH
VRAFVQRSNEVLTRLTRPQ
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TVLEQGSITIHTENIFPIIKQSLYSDREIFLRELISNAADAITKLKMASLAGEVADLPE
CEEECCCEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PEITIALNKEAKTLAVADNGIGMTAEEVKKYINQVAFSSAEEFIQKYKGKDAEQAIIGHF
CCEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GLGFYSSFMVSQRVEIDTLSYRPGSTPVKWACDGTTTFTLSDSERSSIGTTVTLYITPEN
HHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCEEEEECCCCCCCCCCEEEEEEECCC
EEYLEPSRIRELVRKYCDFIPVPIKLNGEVINKQKPLWRTSPSELKDEDYLEFYRYLYPF
CCCCCHHHHHHHHHHHHCCCCCCEEECCEEECCCCCCCCCCHHHCCCHHHHHHHHHHCCC
QEDPHFWVHINTDYPFIVQGILYFPKLRPDIDPTKGQVKLFCNQVFVQDNCEEVIPKFLL
CCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHH
PLRGAIDSPDIPLNVSRSFLQNDRTVRRIGDHVAKKVADRLNELYREDYEKYVKVWPDIS
HHCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LFMKFGAMNNDKFFAQIKDILIFRVAGSPADKPEYVTLKAYLERTRDKQNKRVYYATDEA
HHHHHCCCCCCHHHHHHHHHHEEEECCCCCCCCCEEEHHHHHHHHHCCCCCEEEEECCHH
AQSAYIDLHRSQGLEVIMLDSWIDSHFSSFLEREYKEEGIQFKRVDSELDETLVDKDKAA
HHHHHHEEHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCHHHH
EIVDPVTQKTRSQKLVDLFRQALGKDKLQIQAEALKSESVPAMILLPETLRRLQELNAVI
HHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHCCCCCEEEECHHHHHHHHHHHHHH
QQKPLEFLEEHTLVLNTAHPLIQNLQSLADQGRDPDLVHLICNHIYDLALITQKSFDPAA
HHHHHHHHHCCCEEEECHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHH
VRAFVQRSNEVLTRLTRPQ
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10722592 [H]