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The map label for this gene is spoVD [H]

Identifier: 86608475

GI number: 86608475

Start: 1033030

End: 1034934

Strand: Direct

Name: spoVD [H]

Synonym: CYB_0996

Alternate gene names: 86608475

Gene position: 1033030-1034934 (Clockwise)

Preceding gene: 86608472

Following gene: 86608480

Centisome position: 33.91

GC content: 59.37

Gene sequence:

>1905_bases
ATGGAAGGCAGACCTAGGGCTAGGGTAGGGCGGCCTGTGCCGAAATCTCTGGAGACAAGGCAAAATGGCCGGCAACTTGC
TCAACGGCGCCGACGCAGAGGTTCTTGGATCCCTTCACCGCGAAGCTCTAGGCAGTGGGGAACAGCGCTGGGATGGCTCT
TGGGGGAGCGGATCCCGACGGCCCGCCAGCTTGACTTTCGCGCCGGCATGACCGGACTGGCTTTGATCATCGCCCTATTT
GTAACAGGAGCACGTCTGGTTTATTTGCAACATCAACAGGCACCCCTATTGCAGCAGCGAGCCGAAGCCCAGCAGCGAGC
CCAGCTAAGACCTTTCATTCCTCGTCGCTCAATTGTGGATCGTCACTCCATTGCCAAGCAGCAGGCAGAATTGCTGGCCG
TAGATCGCCCCGTCTATACTCTCTGGGCCCATCCCCGCCTCTTTGGCAAACGCACTCCAGAGGAAATTGCCACCGCTCTT
GCTCCCCTGTTGCGGCGTCCAGTAGAGCAACTGGCGCAGCGGCTATCGGCCAATCAGGCAGTGCGGGTGGAGCGCTGGGT
ATCCCAGGAGGTGGCAGATCAAATTCAGGCTCTGCATCTGGATGGCCTGGAGCTGGTGAGCGAGCGGCAACGCATTTACC
CCCAAAAAGAGATGGCCGCCGAGGTGGTAGGCTATGTAGATCTGGATCATCAGGGCCAAGCAGGAGTCGAATATTCCCGA
CAAGAGCTGCTGGAGCGTACCGTTCAACCTGTTACTATTCCTCGCGATGGCTACGGACGACTGTTGGCTGCCGAGGTGCC
GGAAGGGCTGCTGCAATCCCGCGAGACGGTGCTGCAACTTACCCTAGATATGCGCCTGCAAAGAGCTGCCCGCGCTGCCC
TGAAAGTGCAACTGGAGCGGTTTCGAGCCCTGCGGGGCACGGTGATTGTCCTCCAGCCCCAGACAGGGGAAATCCTGGCG
CTGGTGAGCGAGCCCACCTATGACCCCAACCGCTACTTTGAGTATGACCCCGGTCTTTTTCGCAACTGGGCCGTAACGGA
TTTGTATGAGCCGGGATCCACCTTCAAGCCCATCAACATTGCCATTGGGTTGGATGCTGGAGCCTTTACAGCAGATGAAC
GGGTCTATGACGAGGGTCGGATTCTCATCGGTCAGTGGCCCATTCAAAATTACGACTACCACCAGCGAGGGGCCCATGGC
TGGATGAGCGTCACGGATATCCTGCGGCAATCCAGCAATGTGGGCATGGTACATCTAATGCGCAAGCTGGATCCCCGCCA
GTACTACAATGCCTTGGTGCGGCTGGGGTTCAACGAGCGCAGTGGCGTGGATTTGCCCTTTGAGCCGGCCAGCCGTTTGA
AACCGCTGCGACAGTTTGTTACGGTGCCGGTGGAGCGGGCCACTGTCGCTTTCGGCCAGGGGCTGGCCCTTACCCCTCTA
CAGTTGGCTGCCATGCACTGCATCATTGCCAATGGCGGACTGAAAGTACAGCCCCATGTGGTGCGAGGCTTGGTGGAAAA
GGATACGGATACTCTGGTTTGGGGATCCCCGCAGCCGCAGCCGGTGCGGGTACTATCCGAGCAAGCCACGCTGGCAGTGC
GTATCCAAATGCGGGATGTGGTGGACTTTGGCACGGGGCAATCGGCCAAGATCGAGGGGTATGAGATCGCTGGCAAAACC
GGCACTGCCCAGAAAGCCGGGCCACGGGGGGGCTATTTGCCCGGCAAGCGCATCACCAGTTTTGTGGGCTACTTCCCGGC
CATTCGCCCCAATTACGTGATCTTGGCGGTGATCGACGAGCCCCAGGGGGAAGATGCCTTCGGCTCGACGACGGCTGCTC
CCGTTGTTCGCTCGGTGATCCAGGAGATCATCGCCCTAGAGGGGATCCGCCCTAACTCTACTTAG

Upstream 100 bases:

>100_bases
GGCTGCTTTTCGGGATCCCAAGGTCTTTCCCAGAAGCTGTGGGGTGGCATAACAGTGGGATGAGCGCCAAACTAGCGGTG
GTGCTCATGTGAGGATTGCA

Downstream 100 bases:

>100_bases
CGCAGCCATAGGAACAAGGGGCGAAGGTGGATGCCAAAGGGGGCCCAGACCGTGAGGAAATGAGCGAAATGCCCGTACTT
TCCTATTGGCTCTTCCTGGA

Product: penicillin-binding protein

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 634; Mature: 634

Protein sequence:

>634_residues
MEGRPRARVGRPVPKSLETRQNGRQLAQRRRRRGSWIPSPRSSRQWGTALGWLLGERIPTARQLDFRAGMTGLALIIALF
VTGARLVYLQHQQAPLLQQRAEAQQRAQLRPFIPRRSIVDRHSIAKQQAELLAVDRPVYTLWAHPRLFGKRTPEEIATAL
APLLRRPVEQLAQRLSANQAVRVERWVSQEVADQIQALHLDGLELVSERQRIYPQKEMAAEVVGYVDLDHQGQAGVEYSR
QELLERTVQPVTIPRDGYGRLLAAEVPEGLLQSRETVLQLTLDMRLQRAARAALKVQLERFRALRGTVIVLQPQTGEILA
LVSEPTYDPNRYFEYDPGLFRNWAVTDLYEPGSTFKPINIAIGLDAGAFTADERVYDEGRILIGQWPIQNYDYHQRGAHG
WMSVTDILRQSSNVGMVHLMRKLDPRQYYNALVRLGFNERSGVDLPFEPASRLKPLRQFVTVPVERATVAFGQGLALTPL
QLAAMHCIIANGGLKVQPHVVRGLVEKDTDTLVWGSPQPQPVRVLSEQATLAVRIQMRDVVDFGTGQSAKIEGYEIAGKT
GTAQKAGPRGGYLPGKRITSFVGYFPAIRPNYVILAVIDEPQGEDAFGSTTAAPVVRSVIQEIIALEGIRPNST

Sequences:

>Translated_634_residues
MEGRPRARVGRPVPKSLETRQNGRQLAQRRRRRGSWIPSPRSSRQWGTALGWLLGERIPTARQLDFRAGMTGLALIIALF
VTGARLVYLQHQQAPLLQQRAEAQQRAQLRPFIPRRSIVDRHSIAKQQAELLAVDRPVYTLWAHPRLFGKRTPEEIATAL
APLLRRPVEQLAQRLSANQAVRVERWVSQEVADQIQALHLDGLELVSERQRIYPQKEMAAEVVGYVDLDHQGQAGVEYSR
QELLERTVQPVTIPRDGYGRLLAAEVPEGLLQSRETVLQLTLDMRLQRAARAALKVQLERFRALRGTVIVLQPQTGEILA
LVSEPTYDPNRYFEYDPGLFRNWAVTDLYEPGSTFKPINIAIGLDAGAFTADERVYDEGRILIGQWPIQNYDYHQRGAHG
WMSVTDILRQSSNVGMVHLMRKLDPRQYYNALVRLGFNERSGVDLPFEPASRLKPLRQFVTVPVERATVAFGQGLALTPL
QLAAMHCIIANGGLKVQPHVVRGLVEKDTDTLVWGSPQPQPVRVLSEQATLAVRIQMRDVVDFGTGQSAKIEGYEIAGKT
GTAQKAGPRGGYLPGKRITSFVGYFPAIRPNYVILAVIDEPQGEDAFGSTTAAPVVRSVIQEIIALEGIRPNST
>Mature_634_residues
MEGRPRARVGRPVPKSLETRQNGRQLAQRRRRRGSWIPSPRSSRQWGTALGWLLGERIPTARQLDFRAGMTGLALIIALF
VTGARLVYLQHQQAPLLQQRAEAQQRAQLRPFIPRRSIVDRHSIAKQQAELLAVDRPVYTLWAHPRLFGKRTPEEIATAL
APLLRRPVEQLAQRLSANQAVRVERWVSQEVADQIQALHLDGLELVSERQRIYPQKEMAAEVVGYVDLDHQGQAGVEYSR
QELLERTVQPVTIPRDGYGRLLAAEVPEGLLQSRETVLQLTLDMRLQRAARAALKVQLERFRALRGTVIVLQPQTGEILA
LVSEPTYDPNRYFEYDPGLFRNWAVTDLYEPGSTFKPINIAIGLDAGAFTADERVYDEGRILIGQWPIQNYDYHQRGAHG
WMSVTDILRQSSNVGMVHLMRKLDPRQYYNALVRLGFNERSGVDLPFEPASRLKPLRQFVTVPVERATVAFGQGLALTPL
QLAAMHCIIANGGLKVQPHVVRGLVEKDTDTLVWGSPQPQPVRVLSEQATLAVRIQMRDVVDFGTGQSAKIEGYEIAGKT
GTAQKAGPRGGYLPGKRITSFVGYFPAIRPNYVILAVIDEPQGEDAFGSTTAAPVVRSVIQEIIALEGIRPNST

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=572, Percent_Identity=29.8951048951049, Blast_Score=211, Evalue=8e-56,
Organism=Escherichia coli, GI1786854, Length=566, Percent_Identity=24.9116607773852, Blast_Score=111, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 70966; Mature: 70966

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGRPRARVGRPVPKSLETRQNGRQLAQRRRRRGSWIPSPRSSRQWGTALGWLLGERIPT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCC
ARQLDFRAGMTGLALIIALFVTGARLVYLQHQQAPLLQQRAEAQQRAQLRPFIPRRSIVD
HHHHHHHCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
RHSIAKQQAELLAVDRPVYTLWAHPRLFGKRTPEEIATALAPLLRRPVEQLAQRLSANQA
HHHHHHHHHHHHHCCCCEEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
VRVERWVSQEVADQIQALHLDGLELVSERQRIYPQKEMAAEVVGYVDLDHQGQAGVEYSR
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHEEECCCCCCCCCHHHH
QELLERTVQPVTIPRDGYGRLLAAEVPEGLLQSRETVLQLTLDMRLQRAARAALKVQLER
HHHHHHHCCCEECCCCCCCCEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRALRGTVIVLQPQTGEILALVSEPTYDPNRYFEYDPGLFRNWAVTDLYEPGSTFKPINI
HHHHCCEEEEEECCCCCEEEEEECCCCCCCCCEECCCCCCCCCCEEECCCCCCCCCCEEE
AIGLDAGAFTADERVYDEGRILIGQWPIQNYDYHQRGAHGWMSVTDILRQSSNVGMVHLM
EEECCCCCCCCCCCEECCCCEEEEECCCCCCCCHHCCCCCHHHHHHHHHCCCCCCHHHHH
RKLDPRQYYNALVRLGFNERSGVDLPFEPASRLKPLRQFVTVPVERATVAFGQGLALTPL
HHCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHH
QLAAMHCIIANGGLKVQPHVVRGLVEKDTDTLVWGSPQPQPVRVLSEQATLAVRIQMRDV
HHHHHHHHEECCCEEECHHHHHHHHHCCCCEEEECCCCCCHHHHHCCCCEEEEEEEEHHH
VDFGTGQSAKIEGYEIAGKTGTAQKAGPRGGYLPGKRITSFVGYFPAIRPNYVILAVIDE
HHCCCCCCCEECCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEC
PQGEDAFGSTTAAPVVRSVIQEIIALEGIRPNST
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MEGRPRARVGRPVPKSLETRQNGRQLAQRRRRRGSWIPSPRSSRQWGTALGWLLGERIPT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCC
ARQLDFRAGMTGLALIIALFVTGARLVYLQHQQAPLLQQRAEAQQRAQLRPFIPRRSIVD
HHHHHHHCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
RHSIAKQQAELLAVDRPVYTLWAHPRLFGKRTPEEIATALAPLLRRPVEQLAQRLSANQA
HHHHHHHHHHHHHCCCCEEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
VRVERWVSQEVADQIQALHLDGLELVSERQRIYPQKEMAAEVVGYVDLDHQGQAGVEYSR
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHEEECCCCCCCCCHHHH
QELLERTVQPVTIPRDGYGRLLAAEVPEGLLQSRETVLQLTLDMRLQRAARAALKVQLER
HHHHHHHCCCEECCCCCCCCEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRALRGTVIVLQPQTGEILALVSEPTYDPNRYFEYDPGLFRNWAVTDLYEPGSTFKPINI
HHHHCCEEEEEECCCCCEEEEEECCCCCCCCCEECCCCCCCCCCEEECCCCCCCCCCEEE
AIGLDAGAFTADERVYDEGRILIGQWPIQNYDYHQRGAHGWMSVTDILRQSSNVGMVHLM
EEECCCCCCCCCCCEECCCCEEEEECCCCCCCCHHCCCCCHHHHHHHHHCCCCCCHHHHH
RKLDPRQYYNALVRLGFNERSGVDLPFEPASRLKPLRQFVTVPVERATVAFGQGLALTPL
HHCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHH
QLAAMHCIIANGGLKVQPHVVRGLVEKDTDTLVWGSPQPQPVRVLSEQATLAVRIQMRDV
HHHHHHHHEECCCEEECHHHHHHHHHCCCCEEEECCCCCCHHHHHCCCCEEEEEEEEHHH
VDFGTGQSAKIEGYEIAGKTGTAQKAGPRGGYLPGKRITSFVGYFPAIRPNYVILAVIDE
HHCCCCCCCEECCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEC
PQGEDAFGSTTAAPVVRSVIQEIIALEGIRPNST
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]