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The map label for this gene is 86608439

Identifier: 86608439

GI number: 86608439

Start: 997526

End: 999121

Strand: Direct

Name: 86608439

Synonym: CYB_0961

Alternate gene names: NA

Gene position: 997526-999121 (Clockwise)

Preceding gene: 86608438

Following gene: 86608442

Centisome position: 32.74

GC content: 64.41

Gene sequence:

>1596_bases
ATGGATAGCAACCGTCCTGTCTCCAACCCCATCCGGTTGCAGGTCATGGCCAACGCTCTGGCGGGGATTGCCGAAGAGAT
GGGGGCGCGCCTCATCCGCGGTTCATACTCGGCCAACATCAAGGAACGGCGGGATTGCTCCACAGCTCTGTTTGACGCGC
AAGGGGCCTGTATTGCCCAGGCAGCCCACATCCCGGTACATCTGGGAGCCCTCTCGGAGGCGGTGCGGGCGGTGGTGGCA
GCCGACCCCTGCCCCGGAGATGTGTTTCTCCTCAACGATCCCTACCAGGGGGGATCCCATCTGCCGGACGTTACGGTGGT
CGCGGCCATTCCCGGCTGGAGGGATCCCGACCGGATTTGCGCCTATGCTGTGAACCGTGCTCATCACGCTGATATTGGAG
GGATGCGCCCTGGCTCCATGCCCGCCGACTCCACAGAACTTTGGCAAGAGGGGCTGGTGATCCCGCCGGTACGGCTGGCT
GGGCTCTCTCTAGAAGGAGAGTTGTACTGGCAGGAGGATCTGCTGCGCCTAATCCTGGCCAATGTGCGCAATGCCGAGCA
GCGGCGGGGGGATCTGCAGGCCCAGGTGGGGGCCAGCGCAGTGGGGATGAGCCGGTTTCGGGAGTTGCTGGCCCGCTTTG
GAGAAGAGGAAGCTTGGCAGTTGATCGCAGGGGTCATCGAGTACAGCCGCCGGCGGATGCGGGCGCAAATTCAGGCTCTG
CCCGATGGGATCTACACGGCTGAGGATTGGTTGGAGGGCTACGGGGATCCGCCCGCGCCCCTTGAGATTCGGGTGCAGGT
GGAAGTAGAGGGCGAGAAGCTGCGGGTGGACTTCACCGGCACTGCTCCGGCCATGGCGGGAAACCTGAACGCGCCCCTGG
CCGTCACCCGCTCGGCGGTGTTGTTTGCCCTGCGCTGTCTGTTGGATCCCACGGCCCCCAGCAATGTCGGCTTGGAGGAT
CCCATCGAGATCGTGGCGCCGCCCGGCTGCTTGGTGAATGCCCAGTTTCCGGCAGCAGTGGTGGCGGGCAATGTGGAAAC
CTCGCAGCGCATTGCCGATGTGGTGTTCAAAGCTCTGGCTCCCGTGGCCGGATTGCGGAGCATCGCTCAGGGGCAGGGCA
CCATGAACAACTGTGTGCTGGGCAACCGCCACTTCACCTACTACGAAACCCTGGGAGGTGGTCAGGGGGCCAGCCGGCAA
CGACCGGGTTTGGACGGAGTGCATGTGGGCATGAGCAATACCCTCAACACCCCCATCGAGGCTCTGGAGCTGGAGTATCC
CCTGCGGGTACTGCGCTACGAGCTACGCCAGGATTCCGGCGGCCATGGCCAACAGCGGGGCGGCTGGGGGCTAATCCGCT
CCATCCAGACTTTGCAGGATTGCACCCTCTCCCTGCTCACCGAGCGGCGCCATTATGCCCCCCAAGGAGAACAGGGGGGT
GGGCCAGGCCAGGTGGGGATCAACCTCCTCAACGGGGATCCCCTACCCGGCAAAATCAGCCGCTCCCTAAAAGCCGGCGA
CGTGATCACCCTCTACACGCCGGGCGGCGGGGCTTGGGGCTCAAACGAGGATGAGCAGGCTCCCGAACCCAGGTAG

Upstream 100 bases:

>100_bases
AATCGCCATACCCTTGCCCGCTGGCAACGTCGTTTGCAGTTCTGGCAAGGGATCCGCAGGGTGGCCGTTTGGCTGCGGCG
CAGGCTTTGATTGGAGAGGT

Downstream 100 bases:

>100_bases
CGCAGGTGGTCAAGAAACAACTGCTCGCAGCGGCGAAGCACCTCATCGCGGCTGGCGAAGTGCTCCAGCCTTTGCACTTC
TTGACCTTTCTCAAACAAAA

Product: hydantoinase/oxoprolinase family protein

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MDSNRPVSNPIRLQVMANALAGIAEEMGARLIRGSYSANIKERRDCSTALFDAQGACIAQAAHIPVHLGALSEAVRAVVA
ADPCPGDVFLLNDPYQGGSHLPDVTVVAAIPGWRDPDRICAYAVNRAHHADIGGMRPGSMPADSTELWQEGLVIPPVRLA
GLSLEGELYWQEDLLRLILANVRNAEQRRGDLQAQVGASAVGMSRFRELLARFGEEEAWQLIAGVIEYSRRRMRAQIQAL
PDGIYTAEDWLEGYGDPPAPLEIRVQVEVEGEKLRVDFTGTAPAMAGNLNAPLAVTRSAVLFALRCLLDPTAPSNVGLED
PIEIVAPPGCLVNAQFPAAVVAGNVETSQRIADVVFKALAPVAGLRSIAQGQGTMNNCVLGNRHFTYYETLGGGQGASRQ
RPGLDGVHVGMSNTLNTPIEALELEYPLRVLRYELRQDSGGHGQQRGGWGLIRSIQTLQDCTLSLLTERRHYAPQGEQGG
GPGQVGINLLNGDPLPGKISRSLKAGDVITLYTPGGGAWGSNEDEQAPEPR

Sequences:

>Translated_531_residues
MDSNRPVSNPIRLQVMANALAGIAEEMGARLIRGSYSANIKERRDCSTALFDAQGACIAQAAHIPVHLGALSEAVRAVVA
ADPCPGDVFLLNDPYQGGSHLPDVTVVAAIPGWRDPDRICAYAVNRAHHADIGGMRPGSMPADSTELWQEGLVIPPVRLA
GLSLEGELYWQEDLLRLILANVRNAEQRRGDLQAQVGASAVGMSRFRELLARFGEEEAWQLIAGVIEYSRRRMRAQIQAL
PDGIYTAEDWLEGYGDPPAPLEIRVQVEVEGEKLRVDFTGTAPAMAGNLNAPLAVTRSAVLFALRCLLDPTAPSNVGLED
PIEIVAPPGCLVNAQFPAAVVAGNVETSQRIADVVFKALAPVAGLRSIAQGQGTMNNCVLGNRHFTYYETLGGGQGASRQ
RPGLDGVHVGMSNTLNTPIEALELEYPLRVLRYELRQDSGGHGQQRGGWGLIRSIQTLQDCTLSLLTERRHYAPQGEQGG
GPGQVGINLLNGDPLPGKISRSLKAGDVITLYTPGGGAWGSNEDEQAPEPR
>Mature_531_residues
MDSNRPVSNPIRLQVMANALAGIAEEMGARLIRGSYSANIKERRDCSTALFDAQGACIAQAAHIPVHLGALSEAVRAVVA
ADPCPGDVFLLNDPYQGGSHLPDVTVVAAIPGWRDPDRICAYAVNRAHHADIGGMRPGSMPADSTELWQEGLVIPPVRLA
GLSLEGELYWQEDLLRLILANVRNAEQRRGDLQAQVGASAVGMSRFRELLARFGEEEAWQLIAGVIEYSRRRMRAQIQAL
PDGIYTAEDWLEGYGDPPAPLEIRVQVEVEGEKLRVDFTGTAPAMAGNLNAPLAVTRSAVLFALRCLLDPTAPSNVGLED
PIEIVAPPGCLVNAQFPAAVVAGNVETSQRIADVVFKALAPVAGLRSIAQGQGTMNNCVLGNRHFTYYETLGGGQGASRQ
RPGLDGVHVGMSNTLNTPIEALELEYPLRVLRYELRQDSGGHGQQRGGWGLIRSIQTLQDCTLSLLTERRHYAPQGEQGG
GPGQVGINLLNGDPLPGKISRSLKAGDVITLYTPGGGAWGSNEDEQAPEPR

Specific function: Unknown

COG id: COG0146

COG function: function code EQ; N-methylhydantoinase B/acetone carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=545, Percent_Identity=41.651376146789, Blast_Score=332, Evalue=6e-91,
Organism=Caenorhabditis elegans, GI133901900, Length=545, Percent_Identity=38.1651376146789, Blast_Score=313, Evalue=2e-85,
Organism=Caenorhabditis elegans, GI133901902, Length=522, Percent_Identity=36.9731800766284, Blast_Score=283, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6322634, Length=559, Percent_Identity=34.1681574239714, Blast_Score=303, Evalue=5e-83,
Organism=Drosophila melanogaster, GI45550492, Length=537, Percent_Identity=37.6163873370577, Blast_Score=303, Evalue=2e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003692 [H]

Pfam domain/function: PF02538 Hydantoinase_B [H]

EC number: 3.5.2.14

Molecular weight: Translated: 56892; Mature: 56892

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSNRPVSNPIRLQVMANALAGIAEEMGARLIRGSYSANIKERRDCSTALFDAQGACIAQ
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHH
AAHIPVHLGALSEAVRAVVAADPCPGDVFLLNDPYQGGSHLPDVTVVAAIPGWRDPDRIC
HCCCCEEHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCEEEEEECCCCCCHHHHH
AYAVNRAHHADIGGMRPGSMPADSTELWQEGLVIPPVRLAGLSLEGELYWQEDLLRLILA
HHHHHCHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHCCEECCCCEEEHHHHHHHHHH
NVRNAEQRRGDLQAQVGASAVGMSRFRELLARFGEEEAWQLIAGVIEYSRRRMRAQIQAL
HHHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
PDGIYTAEDWLEGYGDPPAPLEIRVQVEVEGEKLRVDFTGTAPAMAGNLNAPLAVTRSAV
CCCCCCHHHHHHCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCCCCCCCCCHHHHHHHH
LFALRCLLDPTAPSNVGLEDPIEIVAPPGCLVNAQFPAAVVAGNVETSQRIADVVFKALA
HHHHHHHCCCCCCCCCCCCCCHHEECCCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHH
PVAGLRSIAQGQGTMNNCVLGNRHFTYYETLGGGQGASRQRPGLDGVHVGMSNTLNTPIE
HHHHHHHHHHCCCCCCCEEECCCCEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCHH
ALELEYPLRVLRYELRQDSGGHGQQRGGWGLIRSIQTLQDCTLSLLTERRHYAPQGEQGG
HHCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GPGQVGINLLNGDPLPGKISRSLKAGDVITLYTPGGGAWGSNEDEQAPEPR
CCCCEEEEEECCCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDSNRPVSNPIRLQVMANALAGIAEEMGARLIRGSYSANIKERRDCSTALFDAQGACIAQ
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHH
AAHIPVHLGALSEAVRAVVAADPCPGDVFLLNDPYQGGSHLPDVTVVAAIPGWRDPDRIC
HCCCCEEHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCEEEEEECCCCCCHHHHH
AYAVNRAHHADIGGMRPGSMPADSTELWQEGLVIPPVRLAGLSLEGELYWQEDLLRLILA
HHHHHCHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHCCEECCCCEEEHHHHHHHHHH
NVRNAEQRRGDLQAQVGASAVGMSRFRELLARFGEEEAWQLIAGVIEYSRRRMRAQIQAL
HHHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
PDGIYTAEDWLEGYGDPPAPLEIRVQVEVEGEKLRVDFTGTAPAMAGNLNAPLAVTRSAV
CCCCCCHHHHHHCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCCCCCCCCCHHHHHHHH
LFALRCLLDPTAPSNVGLEDPIEIVAPPGCLVNAQFPAAVVAGNVETSQRIADVVFKALA
HHHHHHHCCCCCCCCCCCCCCHHEECCCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHH
PVAGLRSIAQGQGTMNNCVLGNRHFTYYETLGGGQGASRQRPGLDGVHVGMSNTLNTPIE
HHHHHHHHHHCCCCCCCEEECCCCEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCHH
ALELEYPLRVLRYELRQDSGGHGQQRGGWGLIRSIQTLQDCTLSLLTERRHYAPQGEQGG
HHCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GPGQVGINLLNGDPLPGKISRSLKAGDVITLYTPGGGAWGSNEDEQAPEPR
CCCCEEEEEECCCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]