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The map label for this gene is ubiB [C]

Identifier: 86608426

GI number: 86608426

Start: 981446

End: 983149

Strand: Direct

Name: ubiB [C]

Synonym: CYB_0946

Alternate gene names: 86608426

Gene position: 981446-983149 (Clockwise)

Preceding gene: 86608425

Following gene: 86608427

Centisome position: 32.21

GC content: 57.45

Gene sequence:

>1704_bases
TTGGGATCACAACCCGTCAAGCCCTATACCGCCTACCGCTGGGCCCGGGAGAACTATACTCGCCAGGGCCGCATGCTGGA
CATTTGGCGATTTGTGCTCACCTGGCTGTTTTACCTTTGGCTGGATCAGCAGGCTTGGAGCTATGGGGGACAACCCACGC
CCGAGCGAAAGGCCCAGCGCCGCCGGGCCAGAGCCATTTGGATCCGCGAAACGCTGCTTAACTTAGGCCCTACTTTTATT
AAAGTGGGGCAGTTTTTCTCCACCCGCGCCGATCTCTTCCCCTCGGAATATGTCGAGGAGCTCTCCAAGCTGCAGGATCG
GGTGCCTGCTTTCAGCTACGAACAGGTGGCGGCAATTGTGCAGCAGGAGCTGGGCAGGCCGATAACCCAAATCTACAGCT
ACTTTGATCCCACCCCTTTGGCCGCTGCCAGCTTGGGGCAGGTGCATCGCGCCAAGCTGAAAACCGGGGAAGAGGTGGTG
GTGAAGGTGCAGCGTCCGGGGCTGACCCGGCTGTTCACCATCGATTTGGAGATCTGCCGTGGGATTGCCGAGTTCTTTCA
GTATCGCACCTCTTGGGGCGGGCCGGGCCGCGACTGGATCGGCATCTACGAAGAGTGTCGGCGCACCCTCTGGGAAGAGG
TGGATTACCTCAATGAGGGCCGCAATGCCGATACCTTCCGTCGCAACTTTCGGGATATGCCGCAAATTGCTGTTCCCAAA
GTGTATTGGCGTTACACCTCTCCTCGCCTGTTGACATTGGAATACCTGCCGGGGATCAAAATCAGCGATTACGAAGCCTT
GAGTGCGGCAGGGTTGGATCGCAAGGTTTTGGCTCGTCTGGGGGCAGAGGCTTATCTGCGGCAACTGCTCAAGGATGGTT
TTTTTCACGCCGATCCCCACCCCGGCAACATTGCCGTGAAGCCCGATGGCACGTTGATCTTCTACGACTTCGGCATGATG
GGCCGCCTGCGCTCCGATGTGAAAGAAAAGCTGATGGGCACGCTGGCAGGTGTGGTCTCCAAAAATGCCGATCAGGTGGT
GGCCTCGCTGGTGGAACTGGGGGTGCTGGTGCCCACCGCCGATCTGGCTCCGGTGCGCCGCTCGGTGCAGTACATGCTGG
ATCACTTTATGGACAAACCCTTTTCCAGCAACTCGGGAGAAATCTCGGTGGCGGCCATTAGCGAAGACCTTTACGAGCTG
GCCTACGATCAGCCGTTTCGTTTTCCGGCTACCTTTACTTTTGTGATGCGGGCCCTGACCACGCTGGAGGGGCTGGGGAA
GGGGCTGGATCCGGAGTTCGACTTTATGGAGGTGGCCAAACCCTTTGCGGAAGAGCTGATGAGTTTAAACGGAAGCAAGA
CTGAGACCCTCTTGGCCCAGGTTGGCCGTCAAGCGGCTGAGTTCACCAGCAGCAGCCTCAGCTTGCCGCGCCGGATCGAG
TCGACCTTGAGCAAGATAGAACAAGGGGAGCTACGCCTGCGGGTGCGATCCAGCGAGACGGAGCGCTTGCTGCGCAAGCT
GAACAACACCGGGCTGGGAGTTAGTTATGCAGTGTTGTTTGCGGCCTTTTTTTTGAGCGCAACTCAGCTCTTTTTGGCCG
GACATGCTACCTTAACGGTTATCACTTTGGTTTTGGCTGCCCTCGCTGCTCTTGCTTTAATCAGAGTACTCTTAAGGTTG
AATCGGTCAGAGCGATTGATGTGA

Upstream 100 bases:

>100_bases
TGGACGACTTGCGGGCGGAAGTGGCGCAGCTGCGCTCCGAGTTGCAGAAGTACCGGAGTCGAAACGCTTGAACGCGAGCC
TTTTGGGATCCCGGACTTCT

Downstream 100 bases:

>100_bases
TGCGACGATATGCCTGCGCTACGGATCCCGGCAAGATCCGCAGCAGCAATCAGGATGCCTACTACTGCGATCCAGAGGGG
CGCTATTTTATTGTTGCCGA

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 567; Mature: 566

Protein sequence:

>567_residues
MGSQPVKPYTAYRWARENYTRQGRMLDIWRFVLTWLFYLWLDQQAWSYGGQPTPERKAQRRRARAIWIRETLLNLGPTFI
KVGQFFSTRADLFPSEYVEELSKLQDRVPAFSYEQVAAIVQQELGRPITQIYSYFDPTPLAAASLGQVHRAKLKTGEEVV
VKVQRPGLTRLFTIDLEICRGIAEFFQYRTSWGGPGRDWIGIYEECRRTLWEEVDYLNEGRNADTFRRNFRDMPQIAVPK
VYWRYTSPRLLTLEYLPGIKISDYEALSAAGLDRKVLARLGAEAYLRQLLKDGFFHADPHPGNIAVKPDGTLIFYDFGMM
GRLRSDVKEKLMGTLAGVVSKNADQVVASLVELGVLVPTADLAPVRRSVQYMLDHFMDKPFSSNSGEISVAAISEDLYEL
AYDQPFRFPATFTFVMRALTTLEGLGKGLDPEFDFMEVAKPFAEELMSLNGSKTETLLAQVGRQAAEFTSSSLSLPRRIE
STLSKIEQGELRLRVRSSETERLLRKLNNTGLGVSYAVLFAAFFLSATQLFLAGHATLTVITLVLAALAALALIRVLLRL
NRSERLM

Sequences:

>Translated_567_residues
MGSQPVKPYTAYRWARENYTRQGRMLDIWRFVLTWLFYLWLDQQAWSYGGQPTPERKAQRRRARAIWIRETLLNLGPTFI
KVGQFFSTRADLFPSEYVEELSKLQDRVPAFSYEQVAAIVQQELGRPITQIYSYFDPTPLAAASLGQVHRAKLKTGEEVV
VKVQRPGLTRLFTIDLEICRGIAEFFQYRTSWGGPGRDWIGIYEECRRTLWEEVDYLNEGRNADTFRRNFRDMPQIAVPK
VYWRYTSPRLLTLEYLPGIKISDYEALSAAGLDRKVLARLGAEAYLRQLLKDGFFHADPHPGNIAVKPDGTLIFYDFGMM
GRLRSDVKEKLMGTLAGVVSKNADQVVASLVELGVLVPTADLAPVRRSVQYMLDHFMDKPFSSNSGEISVAAISEDLYEL
AYDQPFRFPATFTFVMRALTTLEGLGKGLDPEFDFMEVAKPFAEELMSLNGSKTETLLAQVGRQAAEFTSSSLSLPRRIE
STLSKIEQGELRLRVRSSETERLLRKLNNTGLGVSYAVLFAAFFLSATQLFLAGHATLTVITLVLAALAALALIRVLLRL
NRSERLM
>Mature_566_residues
GSQPVKPYTAYRWARENYTRQGRMLDIWRFVLTWLFYLWLDQQAWSYGGQPTPERKAQRRRARAIWIRETLLNLGPTFIK
VGQFFSTRADLFPSEYVEELSKLQDRVPAFSYEQVAAIVQQELGRPITQIYSYFDPTPLAAASLGQVHRAKLKTGEEVVV
KVQRPGLTRLFTIDLEICRGIAEFFQYRTSWGGPGRDWIGIYEECRRTLWEEVDYLNEGRNADTFRRNFRDMPQIAVPKV
YWRYTSPRLLTLEYLPGIKISDYEALSAAGLDRKVLARLGAEAYLRQLLKDGFFHADPHPGNIAVKPDGTLIFYDFGMMG
RLRSDVKEKLMGTLAGVVSKNADQVVASLVELGVLVPTADLAPVRRSVQYMLDHFMDKPFSSNSGEISVAAISEDLYELA
YDQPFRFPATFTFVMRALTTLEGLGKGLDPEFDFMEVAKPFAEELMSLNGSKTETLLAQVGRQAAEFTSSSLSLPRRIES
TLSKIEQGELRLRVRSSETERLLRKLNNTGLGVSYAVLFAAFFLSATQLFLAGHATLTVITLVLAALAALALIRVLLRLN
RSERLM

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=251, Percent_Identity=31.4741035856574, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI41393593, Length=284, Percent_Identity=31.6901408450704, Blast_Score=148, Evalue=2e-35,
Organism=Homo sapiens, GI217035081, Length=249, Percent_Identity=29.3172690763052, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI32261307, Length=338, Percent_Identity=23.3727810650888, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI34147522, Length=297, Percent_Identity=24.9158249158249, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI27363457, Length=302, Percent_Identity=24.5033112582781, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI217416386, Length=249, Percent_Identity=24.8995983935743, Blast_Score=70, Evalue=7e-12,
Organism=Escherichia coli, GI2367309, Length=425, Percent_Identity=30.8235294117647, Blast_Score=195, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI17559152, Length=302, Percent_Identity=31.1258278145695, Blast_Score=145, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI32565180, Length=265, Percent_Identity=27.1698113207547, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323282, Length=261, Percent_Identity=28.3524904214559, Blast_Score=121, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6325148, Length=451, Percent_Identity=21.9512195121951, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321319, Length=183, Percent_Identity=31.6939890710383, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24662575, Length=379, Percent_Identity=32.1899736147757, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI22024280, Length=286, Percent_Identity=33.9160839160839, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI18859849, Length=322, Percent_Identity=27.3291925465839, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 64360; Mature: 64229

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSQPVKPYTAYRWARENYTRQGRMLDIWRFVLTWLFYLWLDQQAWSYGGQPTPERKAQR
CCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
RRARAIWIRETLLNLGPTFIKVGQFFSTRADLFPSEYVEELSKLQDRVPAFSYEQVAAIV
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
QQELGRPITQIYSYFDPTPLAAASLGQVHRAKLKTGEEVVVKVQRPGLTRLFTIDLEICR
HHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEHHHHHH
GIAEFFQYRTSWGGPGRDWIGIYEECRRTLWEEVDYLNEGRNADTFRRNFRDMPQIAVPK
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHCCH
VYWRYTSPRLLTLEYLPGIKISDYEALSAAGLDRKVLARLGAEAYLRQLLKDGFFHADPH
HEEEECCCCEEEEECCCCCCCCCCHHHHHCCCCHHHHHHHCHHHHHHHHHHCCCCCCCCC
PGNIAVKPDGTLIFYDFGMMGRLRSDVKEKLMGTLAGVVSKNADQVVASLVELGVLVPTA
CCEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
DLAPVRRSVQYMLDHFMDKPFSSNSGEISVAAISEDLYELAYDQPFRFPATFTFVMRALT
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
TLEGLGKGLDPEFDFMEVAKPFAEELMSLNGSKTETLLAQVGRQAAEFTSSSLSLPRRIE
HHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
STLSKIEQGELRLRVRSSETERLLRKLNNTGLGVSYAVLFAAFFLSATQLFLAGHATLTV
HHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITLVLAALAALALIRVLLRLNRSERLM
HHHHHHHHHHHHHHHHHHHHCHHHCCC
>Mature Secondary Structure 
GSQPVKPYTAYRWARENYTRQGRMLDIWRFVLTWLFYLWLDQQAWSYGGQPTPERKAQR
CCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
RRARAIWIRETLLNLGPTFIKVGQFFSTRADLFPSEYVEELSKLQDRVPAFSYEQVAAIV
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
QQELGRPITQIYSYFDPTPLAAASLGQVHRAKLKTGEEVVVKVQRPGLTRLFTIDLEICR
HHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEHHHHHH
GIAEFFQYRTSWGGPGRDWIGIYEECRRTLWEEVDYLNEGRNADTFRRNFRDMPQIAVPK
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHCCH
VYWRYTSPRLLTLEYLPGIKISDYEALSAAGLDRKVLARLGAEAYLRQLLKDGFFHADPH
HEEEECCCCEEEEECCCCCCCCCCHHHHHCCCCHHHHHHHCHHHHHHHHHHCCCCCCCCC
PGNIAVKPDGTLIFYDFGMMGRLRSDVKEKLMGTLAGVVSKNADQVVASLVELGVLVPTA
CCEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
DLAPVRRSVQYMLDHFMDKPFSSNSGEISVAAISEDLYELAYDQPFRFPATFTFVMRALT
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
TLEGLGKGLDPEFDFMEVAKPFAEELMSLNGSKTETLLAQVGRQAAEFTSSSLSLPRRIE
HHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
STLSKIEQGELRLRVRSSETERLLRKLNNTGLGVSYAVLFAAFFLSATQLFLAGHATLTV
HHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITLVLAALAALALIRVLLRLNRSERLM
HHHHHHHHHHHHHHHHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]