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The map label for this gene is wzb [C]

Identifier: 86608386

GI number: 86608386

Start: 935939

End: 936439

Strand: Direct

Name: wzb [C]

Synonym: CYB_0906

Alternate gene names: 86608386

Gene position: 935939-936439 (Clockwise)

Preceding gene: 86608385

Following gene: 86608388

Centisome position: 30.72

GC content: 56.29

Gene sequence:

>501_bases
ATGAGCCAAAAGCTTCTGTTTGTCTGTCTGGGTAACATCTGTCGCTCTCCCACTGCTGAGGGCATCACCAATCACCTTTT
GCGCAGCAGCGGCCATAAGGAAGCAATTATCTGCGACTCAGCAGGTACGGCAGCCTATCACATCGGCAGCCCCCCAGATA
GGCGCATGCAACAAGCAGCCCGATGCTATGGCCTAGAGCTACAAGGCAAGGCCCGCCAGATTCGACCTGCCGACCTGCGC
GAGTTTGACCTGATCCTGGCTATGGATCGACAAAATTACCGCGACATTCTCAGCTTGGATCCCCAGGGAAAATATGCCGA
GAAAGTGCGCCTGATGTGCAGCTATTGCCGCTCTCATTCTGACGAAGAAGTTCCGGATCCCTACTACGGGGGTGAGGCTG
GATTCCATTACGTGATCGAGCTGCTCTGGGATGCCTGTAGCGGCTTGCTGGAATCCCTGGTTCCCGGGATCCAATGCCCA
CCGTTGCCCCCCCGTGCTTGA

Upstream 100 bases:

>100_bases
AGCGGCTCTTGGTGGAAAATAGAAAGGGAATCCGTCCCGCTGTTGCAGGCGGATACATCCTGTGGTGGGCCCACACATGG
GATCCGATGGGGAGGTTGCC

Downstream 100 bases:

>100_bases
GAGCTTGTGTGTTTATTTAAAGTTAATTCAAATGGCGATGAGACGGTAGCCAGTACAATAGCTCCGTTTGCGATAGTCAT
TCCGAATAAGTCTGGGACAT

Product: low molecular weight phosphotyrosine protein phosphatase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MSQKLLFVCLGNICRSPTAEGITNHLLRSSGHKEAIICDSAGTAAYHIGSPPDRRMQQAARCYGLELQGKARQIRPADLR
EFDLILAMDRQNYRDILSLDPQGKYAEKVRLMCSYCRSHSDEEVPDPYYGGEAGFHYVIELLWDACSGLLESLVPGIQCP
PLPPRA

Sequences:

>Translated_166_residues
MSQKLLFVCLGNICRSPTAEGITNHLLRSSGHKEAIICDSAGTAAYHIGSPPDRRMQQAARCYGLELQGKARQIRPADLR
EFDLILAMDRQNYRDILSLDPQGKYAEKVRLMCSYCRSHSDEEVPDPYYGGEAGFHYVIELLWDACSGLLESLVPGIQCP
PLPPRA
>Mature_165_residues
SQKLLFVCLGNICRSPTAEGITNHLLRSSGHKEAIICDSAGTAAYHIGSPPDRRMQQAARCYGLELQGKARQIRPADLRE
FDLILAMDRQNYRDILSLDPQGKYAEKVRLMCSYCRSHSDEEVPDPYYGGEAGFHYVIELLWDACSGLLESLVPGIQCPP
LPPRA

Specific function: Dephosphorylates Wzc. Required For The Extracellular Polysaccharide Colanic Acid Synthesis. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=151, Percent_Identity=39.0728476821192, Blast_Score=104, Evalue=3e-23,
Organism=Homo sapiens, GI6005988, Length=151, Percent_Identity=36.4238410596026, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI96304457, Length=79, Percent_Identity=43.0379746835443, Blast_Score=71, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6325330, Length=136, Percent_Identity=33.0882352941176, Blast_Score=89, Evalue=5e-19,
Organism=Drosophila melanogaster, GI78706770, Length=153, Percent_Identity=35.2941176470588, Blast_Score=90, Evalue=8e-19,
Organism=Drosophila melanogaster, GI78706772, Length=153, Percent_Identity=35.2941176470588, Blast_Score=90, Evalue=8e-19,
Organism=Drosophila melanogaster, GI78706766, Length=153, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=8e-19,
Organism=Drosophila melanogaster, GI78706768, Length=153, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=8e-19,
Organism=Drosophila melanogaster, GI78711846, Length=153, Percent_Identity=35.2941176470588, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI78706764, Length=129, Percent_Identity=35.6589147286822, Blast_Score=86, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 18495; Mature: 18364

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKLLFVCLGNICRSPTAEGITNHLLRSSGHKEAIICDSAGTAAYHIGSPPDRRMQQAA
CCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEECCCCCEEEECCCCHHHHHHHHH
RCYGLELQGKARQIRPADLREFDLILAMDRQNYRDILSLDPQGKYAEKVRLMCSYCRSHS
HHHCCCCCCCCCCCCCCCCHHHHHEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCC
DEEVPDPYYGGEAGFHYVIELLWDACSGLLESLVPGIQCPPLPPRA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SQKLLFVCLGNICRSPTAEGITNHLLRSSGHKEAIICDSAGTAAYHIGSPPDRRMQQAA
CCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEECCCCCEEEECCCCHHHHHHHHH
RCYGLELQGKARQIRPADLREFDLILAMDRQNYRDILSLDPQGKYAEKVRLMCSYCRSHS
HHHCCCCCCCCCCCCCCCCHHHHHEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCC
DEEVPDPYYGGEAGFHYVIELLWDACSGLLESLVPGIQCPPLPPRA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]