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The map label for this gene is yggW [C]

Identifier: 86608370

GI number: 86608370

Start: 922573

End: 923790

Strand: Direct

Name: yggW [C]

Synonym: CYB_0890

Alternate gene names: 86608370

Gene position: 922573-923790 (Clockwise)

Preceding gene: 86608364

Following gene: 86608372

Centisome position: 30.28

GC content: 57.8

Gene sequence:

>1218_bases
ATGGCTGTGGCAATTGCTTCGCACGATCCCACTCCGACCGGTACTGCTCCGCAACCCTGTCGCGACCAGGTTGATTGGCC
TGAGGCGGCTTACCTGCACATCCCTTTTTGTCGGCAACGCTGCCACTACTGTGATTTTGCCACCGGCCTGGGCACCCGCA
AGTTGATGGAAACCTACGTGCAGATGCTCTGCCGGGAGATCGGCGGCGCCTACCGCTACCGCCATCTGGCCGGGGATCCC
AGACCGTTGACCAGCATTTTTTTCGGGGGTGGCACCCCTTCTCTGCTGACGGTGGAGCAACTGGGGCGGATCTTGACTCA
ATTGAGGGAGAGGATCCCGTTTCATCCCGACTGCGAGATTTCTCTGGAGGCCAACCCCGGCACCCTGACGCGGGAGCAGT
TGGCGGGCTACCGGGAGCTGGGGGTCAACCGCATCAGCCTAGGGGTACAGGCATTTCAGCCAGAGCTGCTGGCCGCTTGT
GGTCGCCTGCATGGAGTGGAGGAAGTTTACGAAGCCGTGGCCGACTTGCAGGCGGCGGGCTTTGAGAATTTCAACCTGGA
TTTGATCTTTGAGCTGCCCTACCAGACTTTGGAACACTGGCAGCAGTCTCTACGAGCTGTTCTTGAGATTAACCCCACCC
ATGTCTCCGTCTATGATCTGACGATTGAACCGGGAACCCGCTTTGGTCGGATGTACCGACCGGGAGCAGCACCTTTGCCC
AGCGAGGAAACCACAGTTGCCATGTACCTAATGGCGCGGGAGCTGCTCACCGAAGCGGGCTACATCCACTACGAAATCTC
CAATTTTGCCCGCCCCGGCTACGCCTGTCGCCACAACCGAGTGTACTGGGAAAATCGCCCTTACTTTGGCTTTGGCATGG
GATCCGTCGGCTACGAGGGGGGACGGCGCATTCAGCAGCCCAAAACCCTTTACCACTACTTCGAGCAGGTGAAAGTCGGA
GTCCACCCTCTCCCTCCTGAAGCATCCCCAGAGGAAGTTTGGATGGATACTTTGATGTTGGGGTTGCGTTTACAGGAAGG
TCTGGATTTGTGCCATTTACAGGAGCGTTTTGGCCACCCAAAGGTCGAGCAAGCTTTGGAGAGGCTGGATCCCTATTTTG
AGAAGGGATGGGCCAGTTGTGAGGCAGGCCGGCTACGGCTGATTCCGCCCGATGGCTGGCTATTTTCCAATGAGATTCTC
AGAGACTTGCTGGCTTGA

Upstream 100 bases:

>100_bases
TAGTCGATTACCGCCAGGCGCACAGCTCCCATGGGATCCCTCCTCGTGAGGAGTTTCGGAGTCTATCAGTATAGTGGTTC
TAACCCGTTTGAGCTGACTC

Downstream 100 bases:

>100_bases
TTCCGACGGTTACTTTCACAAGATTTCTCACCAGAGCCCCCTATCCCAATTGGCCGAAAACTCAAGCTTTGAGGAGCGTA
GGCCATCACCATTTCCAGCA

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MAVAIASHDPTPTGTAPQPCRDQVDWPEAAYLHIPFCRQRCHYCDFATGLGTRKLMETYVQMLCREIGGAYRYRHLAGDP
RPLTSIFFGGGTPSLLTVEQLGRILTQLRERIPFHPDCEISLEANPGTLTREQLAGYRELGVNRISLGVQAFQPELLAAC
GRLHGVEEVYEAVADLQAAGFENFNLDLIFELPYQTLEHWQQSLRAVLEINPTHVSVYDLTIEPGTRFGRMYRPGAAPLP
SEETTVAMYLMARELLTEAGYIHYEISNFARPGYACRHNRVYWENRPYFGFGMGSVGYEGGRRIQQPKTLYHYFEQVKVG
VHPLPPEASPEEVWMDTLMLGLRLQEGLDLCHLQERFGHPKVEQALERLDPYFEKGWASCEAGRLRLIPPDGWLFSNEIL
RDLLA

Sequences:

>Translated_405_residues
MAVAIASHDPTPTGTAPQPCRDQVDWPEAAYLHIPFCRQRCHYCDFATGLGTRKLMETYVQMLCREIGGAYRYRHLAGDP
RPLTSIFFGGGTPSLLTVEQLGRILTQLRERIPFHPDCEISLEANPGTLTREQLAGYRELGVNRISLGVQAFQPELLAAC
GRLHGVEEVYEAVADLQAAGFENFNLDLIFELPYQTLEHWQQSLRAVLEINPTHVSVYDLTIEPGTRFGRMYRPGAAPLP
SEETTVAMYLMARELLTEAGYIHYEISNFARPGYACRHNRVYWENRPYFGFGMGSVGYEGGRRIQQPKTLYHYFEQVKVG
VHPLPPEASPEEVWMDTLMLGLRLQEGLDLCHLQERFGHPKVEQALERLDPYFEKGWASCEAGRLRLIPPDGWLFSNEIL
RDLLA
>Mature_404_residues
AVAIASHDPTPTGTAPQPCRDQVDWPEAAYLHIPFCRQRCHYCDFATGLGTRKLMETYVQMLCREIGGAYRYRHLAGDPR
PLTSIFFGGGTPSLLTVEQLGRILTQLRERIPFHPDCEISLEANPGTLTREQLAGYRELGVNRISLGVQAFQPELLAACG
RLHGVEEVYEAVADLQAAGFENFNLDLIFELPYQTLEHWQQSLRAVLEINPTHVSVYDLTIEPGTRFGRMYRPGAAPLPS
EETTVAMYLMARELLTEAGYIHYEISNFARPGYACRHNRVYWENRPYFGFGMGSVGYEGGRRIQQPKTLYHYFEQVKVGV
HPLPPEASPEEVWMDTLMLGLRLQEGLDLCHLQERFGHPKVEQALERLDPYFEKGWASCEAGRLRLIPPDGWLFSNEILR
DLLA

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=269, Percent_Identity=34.9442379182156, Blast_Score=156, Evalue=3e-38,
Organism=Escherichia coli, GI1789325, Length=287, Percent_Identity=41.4634146341463, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI87082341, Length=305, Percent_Identity=31.1475409836066, Blast_Score=137, Evalue=9e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 45987; Mature: 45856

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVAIASHDPTPTGTAPQPCRDQVDWPEAAYLHIPFCRQRCHYCDFATGLGTRKLMETYV
CEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHCCCCHHHHCCCHHHHHHHHH
QMLCREIGGAYRYRHLAGDPRPLTSIFFGGGTPSLLTVEQLGRILTQLRERIPFHPDCEI
HHHHHHHCCHHHHHHCCCCCCCCCEEEECCCCCCEEEHHHHHHHHHHHHHHCCCCCCCEE
SLEANPGTLTREQLAGYRELGVNRISLGVQAFQPELLAACGRLHGVEEVYEAVADLQAAG
EEECCCCCCCHHHHCCHHHHCCCCEEHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHCC
FENFNLDLIFELPYQTLEHWQQSLRAVLEINPTHVSVYDLTIEPGTRFGRMYRPGAAPLP
CCCCCEEEEEECCHHHHHHHHHHHHHHHEECCCEEEEEEEEECCCCHHCCCCCCCCCCCC
SEETTVAMYLMARELLTEAGYIHYEISNFARPGYACRHNRVYWENRPYFGFGMGSVGYEG
CCCHHHHHHHHHHHHHHHCCEEEEEHHHCCCCCCCCCCCCEEECCCCEEEECCCCCCCCC
GRRIQQPKTLYHYFEQVKVGVHPLPPEASPEEVWMDTLMLGLRLQEGLDLCHLQERFGHP
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
KVEQALERLDPYFEKGWASCEAGRLRLIPPDGWLFSNEILRDLLA
HHHHHHHHHCHHHHHCCCCCCCCCEEEECCCCCEEHHHHHHHHHC
>Mature Secondary Structure 
AVAIASHDPTPTGTAPQPCRDQVDWPEAAYLHIPFCRQRCHYCDFATGLGTRKLMETYV
EEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHCCCCHHHHCCCHHHHHHHHH
QMLCREIGGAYRYRHLAGDPRPLTSIFFGGGTPSLLTVEQLGRILTQLRERIPFHPDCEI
HHHHHHHCCHHHHHHCCCCCCCCCEEEECCCCCCEEEHHHHHHHHHHHHHHCCCCCCCEE
SLEANPGTLTREQLAGYRELGVNRISLGVQAFQPELLAACGRLHGVEEVYEAVADLQAAG
EEECCCCCCCHHHHCCHHHHCCCCEEHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHCC
FENFNLDLIFELPYQTLEHWQQSLRAVLEINPTHVSVYDLTIEPGTRFGRMYRPGAAPLP
CCCCCEEEEEECCHHHHHHHHHHHHHHHEECCCEEEEEEEEECCCCHHCCCCCCCCCCCC
SEETTVAMYLMARELLTEAGYIHYEISNFARPGYACRHNRVYWENRPYFGFGMGSVGYEG
CCCHHHHHHHHHHHHHHHCCEEEEEHHHCCCCCCCCCCCCEEECCCCEEEECCCCCCCCC
GRRIQQPKTLYHYFEQVKVGVHPLPPEASPEEVWMDTLMLGLRLQEGLDLCHLQERFGHP
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
KVEQALERLDPYFEKGWASCEAGRLRLIPPDGWLFSNEILRDLLA
HHHHHHHHHCHHHHHCCCCCCCCCEEEECCCCCEEHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]