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The map label for this gene is ndhH [H]

Identifier: 86608353

GI number: 86608353

Start: 902951

End: 904129

Strand: Reverse

Name: ndhH [H]

Synonym: CYB_0872

Alternate gene names: 86608353

Gene position: 904129-902951 (Counterclockwise)

Preceding gene: 86608355

Following gene: 86608352

Centisome position: 29.68

GC content: 58.35

Gene sequence:

>1179_bases
ATGATCGAGACCCGTACCGACCGGATGTTGCTCAACTTTGGGCCGCACCATCCCTCTATGCATGGGGTTTTGCGTTTGCT
GGTCACCCTAGATGGCGAAAACATCGTCGATTGCGAACCGGTGATCGGCTACTTGCACCGCGGCATGGAGAAAATCGCCG
AAAACCGCACGGTGGTGCAATACCTGCCCTACGTCTCCCGTTGGGACTACGGGGCCGGCATGTTTAACGAGGCCATTACC
GTCAATGCCGTTGAGAAACTGGCCGGGATCAGCGTGCCCAGACGGGCAAGCTACCTACGGGTGATCATGTTGGAGCTGAC
CCGCATCACCAACCACCTGCTTTGGTTTGGTCCCTTCTTGGCGGATTTGGGCGCCCAAACCCCCTTCCTCTACGCCATGC
GGGAGCGGGAGTGGATCCTAGACTTGTTTGAAGCCGTCACCGGCATGCGCTTGATCAACAACAACTATTTCCGGGTGGGC
GGCGTGGCGGTGGACTTGCCCTACGGCTGGACGGAAAAATGCCTAGACTTTTGCGAGTATTTCTTGCCCAAAGTGGATGA
ATACGAGCGGCTGGTTACCGACAACCCGATTTTCCGCCGGCGGCTGGAAGGGGTGGGAGCCATCTCCAAGCAAGACGCCA
TCAACTGGGGTCTGTCGGGTCCCATGTTGCGGGCCTGCGGCGTCAACTGGGATCTGCGCAAAGTGGATCACTACGAGTGC
TACGACGACTTCGACTGGGAGGTGGCCGTTTACCCCGAAGGGGATTGCCTGGCCCGCTATCGGGTGCGCATGAAAGAGAT
GCGGGAGTCCTGCAAGATCGTGCAGCAAGCGGTGAAGGCTCTGCCGGGCGGCCCCTTTGAAAACCTAGAAGCCAAGCGCA
TGCTGGAGGGGCCGAAGTCGGAGTGGAACAAAGGGGACTACCAGTTCATCAGCAAAAAGCCTTCCGCCAATTTCAAGATC
CCCAAAGGGGAAGCCTACGTGCGGGTGGAGAGCGCCAAAGGAGAGCTGGGCATTTACATCGTGGGAGACGACAACGTCTG
CCCGTGGCGCTGGAAGATCCGCCCCCCCGGCTTTGTCAATTTGCAGGTACTGCCTCAGTTGATTCGCGGCATGAAGGTAG
CCGACATGATCGCCATCCTCGGCAGCATTGACATCATCATGGGCGAGGTGGATCGCTAA

Upstream 100 bases:

>100_bases
GGCATGGGATCCCGAGAAGGCAGAAGAAAACCGCTATACTGCAAATGTTGCAGACCATGAACATTCTTCAGTTGCGGAGG
CGGCGGCTATGCCCATGCCC

Downstream 100 bases:

>100_bases
GATACTTACGGAAAGCGAGGACAAAGGCAATGGCCTGGGCGATCTTGGTTCTGCCGCTGTTGATTGTGTCTGTCATTGCT
GCGGTTATCGGCCCCAAGCA

Product: NAD(P)H-quinone oxidoreductase subunit H

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase subunit H; NADH-plastoquinone oxidoreductase subunit H; NDH-1 subunit H; NDH-H [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MIETRTDRMLLNFGPHHPSMHGVLRLLVTLDGENIVDCEPVIGYLHRGMEKIAENRTVVQYLPYVSRWDYGAGMFNEAIT
VNAVEKLAGISVPRRASYLRVIMLELTRITNHLLWFGPFLADLGAQTPFLYAMREREWILDLFEAVTGMRLINNNYFRVG
GVAVDLPYGWTEKCLDFCEYFLPKVDEYERLVTDNPIFRRRLEGVGAISKQDAINWGLSGPMLRACGVNWDLRKVDHYEC
YDDFDWEVAVYPEGDCLARYRVRMKEMRESCKIVQQAVKALPGGPFENLEAKRMLEGPKSEWNKGDYQFISKKPSANFKI
PKGEAYVRVESAKGELGIYIVGDDNVCPWRWKIRPPGFVNLQVLPQLIRGMKVADMIAILGSIDIIMGEVDR

Sequences:

>Translated_392_residues
MIETRTDRMLLNFGPHHPSMHGVLRLLVTLDGENIVDCEPVIGYLHRGMEKIAENRTVVQYLPYVSRWDYGAGMFNEAIT
VNAVEKLAGISVPRRASYLRVIMLELTRITNHLLWFGPFLADLGAQTPFLYAMREREWILDLFEAVTGMRLINNNYFRVG
GVAVDLPYGWTEKCLDFCEYFLPKVDEYERLVTDNPIFRRRLEGVGAISKQDAINWGLSGPMLRACGVNWDLRKVDHYEC
YDDFDWEVAVYPEGDCLARYRVRMKEMRESCKIVQQAVKALPGGPFENLEAKRMLEGPKSEWNKGDYQFISKKPSANFKI
PKGEAYVRVESAKGELGIYIVGDDNVCPWRWKIRPPGFVNLQVLPQLIRGMKVADMIAILGSIDIIMGEVDR
>Mature_392_residues
MIETRTDRMLLNFGPHHPSMHGVLRLLVTLDGENIVDCEPVIGYLHRGMEKIAENRTVVQYLPYVSRWDYGAGMFNEAIT
VNAVEKLAGISVPRRASYLRVIMLELTRITNHLLWFGPFLADLGAQTPFLYAMREREWILDLFEAVTGMRLINNNYFRVG
GVAVDLPYGWTEKCLDFCEYFLPKVDEYERLVTDNPIFRRRLEGVGAISKQDAINWGLSGPMLRACGVNWDLRKVDHYEC
YDDFDWEVAVYPEGDCLARYRVRMKEMRESCKIVQQAVKALPGGPFENLEAKRMLEGPKSEWNKGDYQFISKKPSANFKI
PKGEAYVRVESAKGELGIYIVGDDNVCPWRWKIRPPGFVNLQVLPQLIRGMKVADMIAILGSIDIIMGEVDR

Specific function: NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758786, Length=393, Percent_Identity=41.2213740458015, Blast_Score=301, Evalue=6e-82,
Organism=Homo sapiens, GI260898743, Length=387, Percent_Identity=40.3100775193798, Blast_Score=289, Evalue=4e-78,
Organism=Escherichia coli, GI145693162, Length=393, Percent_Identity=40.2035623409669, Blast_Score=303, Evalue=1e-83,
Organism=Escherichia coli, GI1789076, Length=383, Percent_Identity=28.1984334203655, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1788832, Length=393, Percent_Identity=28.498727735369, Blast_Score=125, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17568379, Length=392, Percent_Identity=41.0714285714286, Blast_Score=315, Evalue=2e-86,
Organism=Caenorhabditis elegans, GI17555284, Length=392, Percent_Identity=40.8163265306122, Blast_Score=315, Evalue=3e-86,
Organism=Drosophila melanogaster, GI221459469, Length=385, Percent_Identity=43.3766233766234, Blast_Score=330, Evalue=1e-90,
Organism=Drosophila melanogaster, GI24638644, Length=393, Percent_Identity=39.6946564885496, Blast_Score=320, Evalue=1e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR014029
- InterPro:   IPR022885 [H]

Pfam domain/function: PF00346 Complex1_49kDa [H]

EC number: 1.6.5.3

Molecular weight: Translated: 44971; Mature: 44971

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00535 COMPLEX1_49K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIETRTDRMLLNFGPHHPSMHGVLRLLVTLDGENIVDCEPVIGYLHRGMEKIAENRTVVQ
CCCCCCCCEEEECCCCCCCHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHH
YLPYVSRWDYGAGMFNEAITVNAVEKLAGISVPRRASYLRVIMLELTRITNHLLWFGPFL
HCCHHHCCCCCCCHHCCCEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ADLGAQTPFLYAMREREWILDLFEAVTGMRLINNNYFRVGGVAVDLPYGWTEKCLDFCEY
HHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEECCCCCHHHHHHHHHH
FLPKVDEYERLVTDNPIFRRRLEGVGAISKQDAINWGLSGPMLRACGVNWDLRKVDHYEC
HCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCC
YDDFDWEVAVYPEGDCLARYRVRMKEMRESCKIVQQAVKALPGGPFENLEAKRMLEGPKS
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCC
EWNKGDYQFISKKPSANFKIPKGEAYVRVESAKGELGIYIVGDDNVCPWRWKIRPPGFVN
CCCCCCEEEEECCCCCCEECCCCCEEEEEECCCCCEEEEEEECCCCCCEEEEECCCCEEH
LQVLPQLIRGMKVADMIAILGSIDIIMGEVDR
HHHHHHHHCCCHHHHHHHHHHHHHHEECCCCC
>Mature Secondary Structure
MIETRTDRMLLNFGPHHPSMHGVLRLLVTLDGENIVDCEPVIGYLHRGMEKIAENRTVVQ
CCCCCCCCEEEECCCCCCCHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHH
YLPYVSRWDYGAGMFNEAITVNAVEKLAGISVPRRASYLRVIMLELTRITNHLLWFGPFL
HCCHHHCCCCCCCHHCCCEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ADLGAQTPFLYAMREREWILDLFEAVTGMRLINNNYFRVGGVAVDLPYGWTEKCLDFCEY
HHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEECCCCCHHHHHHHHHH
FLPKVDEYERLVTDNPIFRRRLEGVGAISKQDAINWGLSGPMLRACGVNWDLRKVDHYEC
HCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCC
YDDFDWEVAVYPEGDCLARYRVRMKEMRESCKIVQQAVKALPGGPFENLEAKRMLEGPKS
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCC
EWNKGDYQFISKKPSANFKIPKGEAYVRVESAKGELGIYIVGDDNVCPWRWKIRPPGFVN
CCCCCCEEEEECCCCCCEECCCCCEEEEEECCCCCEEEEEEECCCCCCEEEEECCCCEEH
LQVLPQLIRGMKVADMIAILGSIDIIMGEVDR
HHHHHHHHCCCHHHHHHHHHHHHHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA