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The map label for this gene is ndhA [H]

Identifier: 86608351

GI number: 86608351

Start: 901540

End: 902601

Strand: Reverse

Name: ndhA [H]

Synonym: CYB_0870

Alternate gene names: 86608351

Gene position: 902601-901540 (Counterclockwise)

Preceding gene: 86608352

Following gene: 86608350

Centisome position: 29.63

GC content: 56.4

Gene sequence:

>1062_bases
TTGGGAGCAGGTGCAGCCCATGCCCTCTGGATGCCCCTGCCCATGTTGCTGCTGATCATCGCCGCCACCTTGGGGGTGAT
GGTCATGACTTGGCTGGAGCGAAAAATCTCGGCAGCAGCCCAACAGCGGATTGGCCCCAACATGGCCGGCCCTCAGGGGG
TGCTGATCCCGATTGCCGATGGCATCAAGCTGCTGACCAAAGAAGATGTTCTGCCCATCTTGGCCGACCCAGTCTTGTTT
ACGCTGGGGCCGATATTGGTTTTCCTGCCCGTCTTTTTGTGCTACCTGGTGGTTCCCTTTGGCCAGAACCTATTGATCTC
TAACATTGCCATTGGCGTGTTCTTCCTGATCGCCATCTCCAGCGTGCAACCCATCGGTTTGTTAATGTCGGGCTACGGTT
CCAATAACAAGTACTCCTTGCTGGGTGGGCTACGAGCGGCAGCTCAATCGATCAGCTACGAACTGCCGCTGGCCCTGTCG
GTGTTGGCCGTGGTGTTGATGAGCAACGGTCTGGACACGGTGGGGATCGTCGAACAGCAGAGTGGCCTGGGCATCTTGAG
CTGGAACGTCTGGCGGCAGCCCATTGGCTTTGTGATTTTCTTGATCTCGGCTCTGGCGGAAACGGAGCGGATCCCGTTCG
ACTTGCCGGAAGCAGAAGAAGAGCTGGTAGCCGGTTACCAAACGGAGTACTCCGGCATGAAGTTTGCCCTCTTTTATCTG
GGATCCTACGCCAACTTGCTGCTGGCTTCTCTGATTGCGGCAGTGCTGTACTTGGGGGGTTGGTCGTTTGTGGTGCCGGT
GGAAACGATTGCTGCACTTGCCGGGATTCCTTTGGATAACCCTTTCTTGCAGATCGGCGCGGCGGCCTTAGGCATTGTCA
TGACGATGGTCAAAGCTTTTATCTTCATCTTCTTGGCCATCCTGCTGCGCTGGACCTTGCCGCGGGTGCGCATTGACCAA
CTGCTGGACTTGGGGTGGAAGTTTTTGCTGCCCGTATCCTTTGTTAACTTGCTGCTGACGGCAGCCCTAAAGCTCGCCTT
CCCCACCTTTTTTGGGGGTTGA

Upstream 100 bases:

>100_bases
CCCTACCCAACCCGCCATCTCTAGGGAGCTACTCACCCCCATGACAAACGCTGGTATCGACCTACAACTTGGCTTCGAGA
CTGCCCTACAGAACCTAGGC

Downstream 100 bases:

>100_bases
ATGAGAAGTAAAGAGGCCAGAGAGGGAGAACATAGGTCATGACGTTTCTCAAGCGTGTCAAAGAATATGTGGGCGATGCC
TTCCGAGCCGCCAAGTACAT

Product: NADH dehydrogenase subunit H

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase I subunit 1; NDH-1 subunit 1; NDH-A [H]

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MGAGAAHALWMPLPMLLLIIAATLGVMVMTWLERKISAAAQQRIGPNMAGPQGVLIPIADGIKLLTKEDVLPILADPVLF
TLGPILVFLPVFLCYLVVPFGQNLLISNIAIGVFFLIAISSVQPIGLLMSGYGSNNKYSLLGGLRAAAQSISYELPLALS
VLAVVLMSNGLDTVGIVEQQSGLGILSWNVWRQPIGFVIFLISALAETERIPFDLPEAEEELVAGYQTEYSGMKFALFYL
GSYANLLLASLIAAVLYLGGWSFVVPVETIAALAGIPLDNPFLQIGAAALGIVMTMVKAFIFIFLAILLRWTLPRVRIDQ
LLDLGWKFLLPVSFVNLLLTAALKLAFPTFFGG

Sequences:

>Translated_353_residues
MGAGAAHALWMPLPMLLLIIAATLGVMVMTWLERKISAAAQQRIGPNMAGPQGVLIPIADGIKLLTKEDVLPILADPVLF
TLGPILVFLPVFLCYLVVPFGQNLLISNIAIGVFFLIAISSVQPIGLLMSGYGSNNKYSLLGGLRAAAQSISYELPLALS
VLAVVLMSNGLDTVGIVEQQSGLGILSWNVWRQPIGFVIFLISALAETERIPFDLPEAEEELVAGYQTEYSGMKFALFYL
GSYANLLLASLIAAVLYLGGWSFVVPVETIAALAGIPLDNPFLQIGAAALGIVMTMVKAFIFIFLAILLRWTLPRVRIDQ
LLDLGWKFLLPVSFVNLLLTAALKLAFPTFFGG
>Mature_352_residues
GAGAAHALWMPLPMLLLIIAATLGVMVMTWLERKISAAAQQRIGPNMAGPQGVLIPIADGIKLLTKEDVLPILADPVLFT
LGPILVFLPVFLCYLVVPFGQNLLISNIAIGVFFLIAISSVQPIGLLMSGYGSNNKYSLLGGLRAAAQSISYELPLALSV
LAVVLMSNGLDTVGIVEQQSGLGILSWNVWRQPIGFVIFLISALAETERIPFDLPEAEEELVAGYQTEYSGMKFALFYLG
SYANLLLASLIAAVLYLGGWSFVVPVETIAALAGIPLDNPFLQIGAAALGIVMTMVKAFIFIFLAILLRWTLPRVRIDQL
LDLGWKFLLPVSFVNLLLTAALKLAFPTFFGG

Specific function: NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=301, Percent_Identity=34.8837209302326, Blast_Score=163, Evalue=2e-40,
Organism=Escherichia coli, GI1788618, Length=331, Percent_Identity=37.7643504531722, Blast_Score=223, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: 1.6.5.3

Molecular weight: Translated: 37962; Mature: 37831

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAGAAHALWMPLPMLLLIIAATLGVMVMTWLERKISAAAQQRIGPNMAGPQGVLIPIAD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCC
GIKLLTKEDVLPILADPVLFTLGPILVFLPVFLCYLVVPFGQNLLISNIAIGVFFLIAIS
CHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SVQPIGLLMSGYGSNNKYSLLGGLRAAAQSISYELPLALSVLAVVLMSNGLDTVGIVEQQ
CCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECC
SGLGILSWNVWRQPIGFVIFLISALAETERIPFDLPEAEEELVAGYQTEYSGMKFALFYL
CCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCHHHHHCCHHHHHHHH
GSYANLLLASLIAAVLYLGGWSFVVPVETIAALAGIPLDNPFLQIGAAALGIVMTMVKAF
HHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
IFIFLAILLRWTLPRVRIDQLLDLGWKFLLPVSFVNLLLTAALKLAFPTFFGG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GAGAAHALWMPLPMLLLIIAATLGVMVMTWLERKISAAAQQRIGPNMAGPQGVLIPIAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCC
GIKLLTKEDVLPILADPVLFTLGPILVFLPVFLCYLVVPFGQNLLISNIAIGVFFLIAIS
CHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SVQPIGLLMSGYGSNNKYSLLGGLRAAAQSISYELPLALSVLAVVLMSNGLDTVGIVEQQ
CCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECC
SGLGILSWNVWRQPIGFVIFLISALAETERIPFDLPEAEEELVAGYQTEYSGMKFALFYL
CCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCHHHHHCCHHHHHHHH
GSYANLLLASLIAAVLYLGGWSFVVPVETIAALAGIPLDNPFLQIGAAALGIVMTMVKAF
HHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
IFIFLAILLRWTLPRVRIDQLLDLGWKFLLPVSFVNLLLTAALKLAFPTFFGG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA