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The map label for this gene is ndhI [H]

Identifier: 86608350

GI number: 86608350

Start: 900869

End: 901501

Strand: Reverse

Name: ndhI [H]

Synonym: CYB_0869

Alternate gene names: 86608350

Gene position: 901501-900869 (Counterclockwise)

Preceding gene: 86608351

Following gene: 86608348

Centisome position: 29.59

GC content: 54.82

Gene sequence:

>633_bases
ATGACGTTTCTCAAGCGTGTCAAAGAATATGTGGGCGATGCCTTCCGAGCCGCCAAGTACATCGGCCAAGGGATGGGGGT
TGTCTTCGACCACATGGGCCGGCGCCCGGTAACCGTGCAATACCCCTTCGAAAAGCTGATCCCCTCTGAGCGCTTTCGGG
GACGCATCCACTTCGAGTTTGATAAGTGTATTGCCTGCGAGATCTGCGTTCGGGTTTGCCCCATTGATCTGCCAGTGGTG
GATTGGGCCTACAACCCAGAGCTGAAGAAAAAGGAGCTCTACAGCTACAGCATTGATTTTGGGGTGTGCATTTTCTGTGC
CAATTGTGTGGAGTTTTGCCCCACCAATTGTCTCTCGGTAACCGAGGATTATGAGTTGGCTACTTACGACCGCCATGACC
TCAACTACCACCAAGTGGCGATGGGCCGTCTGCCCTCTAAAGTTACCGAAGACCCGATGGTGACCCCCTTGCGAGAATTT
GCCTATCTGCCCAAAGGGGTAATCGATCCCCACGACTTACCTGCTGGATCCCAGCGGGCTGGCAAACGACCGGAGGAGAT
TCTGGCGGAAATGAGAGCGGCCAAAGCTGCTAAGGAAGCCGAAGCGAAAGCAGCCAAGGCTGCTGCGGAATAG

Upstream 100 bases:

>100_bases
TTGTTAACTTGCTGCTGACGGCAGCCCTAAAGCTCGCCTTCCCCACCTTTTTTGGGGGTTGAATGAGAAGTAAAGAGGCC
AGAGAGGGAGAACATAGGTC

Downstream 100 bases:

>100_bases
CGTGACATACTCCCGCACTCATGCTGACGCAAAGCGCTCCGCGCCGCTGTCCGCCACCCCTAGCCCCTTTCCCAGGGGAT
GTGACTGTTTGAACTTGTGG

Product: NADH dehydrogenase subunit I

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase I subunit I; NDH-1 subunit I; NDH-I [H]

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MTFLKRVKEYVGDAFRAAKYIGQGMGVVFDHMGRRPVTVQYPFEKLIPSERFRGRIHFEFDKCIACEICVRVCPIDLPVV
DWAYNPELKKKELYSYSIDFGVCIFCANCVEFCPTNCLSVTEDYELATYDRHDLNYHQVAMGRLPSKVTEDPMVTPLREF
AYLPKGVIDPHDLPAGSQRAGKRPEEILAEMRAAKAAKEAEAKAAKAAAE

Sequences:

>Translated_210_residues
MTFLKRVKEYVGDAFRAAKYIGQGMGVVFDHMGRRPVTVQYPFEKLIPSERFRGRIHFEFDKCIACEICVRVCPIDLPVV
DWAYNPELKKKELYSYSIDFGVCIFCANCVEFCPTNCLSVTEDYELATYDRHDLNYHQVAMGRLPSKVTEDPMVTPLREF
AYLPKGVIDPHDLPAGSQRAGKRPEEILAEMRAAKAAKEAEAKAAKAAAE
>Mature_209_residues
TFLKRVKEYVGDAFRAAKYIGQGMGVVFDHMGRRPVTVQYPFEKLIPSERFRGRIHFEFDKCIACEICVRVCPIDLPVVD
WAYNPELKKKELYSYSIDFGVCIFCANCVEFCPTNCLSVTEDYELATYDRHDLNYHQVAMGRLPSKVTEDPMVTPLREFA
YLPKGVIDPHDLPAGSQRAGKRPEEILAEMRAAKAAKEAEAKAAKAAAE

Specific function: NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone

COG id: COG1143

COG function: function code C; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI4505371, Length=121, Percent_Identity=30.5785123966942, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1788617, Length=108, Percent_Identity=36.1111111111111, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789075, Length=97, Percent_Identity=34.020618556701, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17555194, Length=121, Percent_Identity=32.2314049586777, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17864306, Length=121, Percent_Identity=30.5785123966942, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR004497
- InterPro:   IPR010226 [H]

Pfam domain/function: NA

EC number: 1.6.5.3

Molecular weight: Translated: 23780; Mature: 23648

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFLKRVKEYVGDAFRAAKYIGQGMGVVFDHMGRRPVTVQYPFEKLIPSERFRGRIHFEF
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEECCHHHCCCCHHHCCEEEEEH
DKCIACEICVRVCPIDLPVVDWAYNPELKKKELYSYSIDFGVCIFCANCVEFCPTNCLSV
HHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCC
TEDYELATYDRHDLNYHQVAMGRLPSKVTEDPMVTPLREFAYLPKGVIDPHDLPAGSQRA
CCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCC
GKRPEEILAEMRAAKAAKEAEAKAAKAAAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TFLKRVKEYVGDAFRAAKYIGQGMGVVFDHMGRRPVTVQYPFEKLIPSERFRGRIHFEF
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEECCHHHCCCCHHHCCEEEEEH
DKCIACEICVRVCPIDLPVVDWAYNPELKKKELYSYSIDFGVCIFCANCVEFCPTNCLSV
HHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCC
TEDYELATYDRHDLNYHQVAMGRLPSKVTEDPMVTPLREFAYLPKGVIDPHDLPAGSQRA
CCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCC
GKRPEEILAEMRAAKAAKEAEAKAAKAAAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA