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The map label for this gene is 86608048

Identifier: 86608048

GI number: 86608048

Start: 566647

End: 567753

Strand: Direct

Name: 86608048

Synonym: CYB_0556

Alternate gene names: NA

Gene position: 566647-567753 (Clockwise)

Preceding gene: 86608042

Following gene: 86608051

Centisome position: 18.6

GC content: 61.88

Gene sequence:

>1107_bases
ATGTACACCGGCACCGCCGCCGGGGAAGTGGTGGGCTTGTCGGATCGCATTTGCCAGGCTTTGCCAGGGTTTGTGCGGGA
GCCGGATCGGCGCAATGTGGAGTACATCACCCCCCCTCTCCGCCGCTACGAAGACCTGCTCTGCGCTCTGCTGCGACCTC
GCCTGCAGTTGCGGCAATTTTTGCGCCGTCTTGGCCCTTACACCCTTCTGCCAGGGAGTACGCTGGCTTTGGGCGGCAGC
GATCACTTCGAGCGGTCGGATCCCGGCAACCCCTACCACGACTACATCGAGCGCACCTATGGCACGCGGGTGGTAACTGC
TAGCATTCACATCAATGTTGGCCTGCCAGGTACCGAGGCCATCTTCCGGGCCTGTCGCCTGCTGCGAGCGGAAGCATCTC
TCTACCTAGCTCTGAGCGCTTCCTCTCCTTTTCTGGACGGACGGGTGACGGGATCCCATTCCAGCCGTTGGCAGGTGTTC
CCCAAAACGCCGGCTCAGGTGCCCTTCTTCCGGGATCACGCCCACTACATTGCCTGGATCCAGGAGCAGCTAGCCTTGGG
CACCATGCAGAATGTGCGCCACCTGTGGGCCTCGGTGCGACCCAACGGCCCGGAGCGGCCCTACCACCTCAACCGCGTGG
AGCTGCGCATTTGCGATCTGGTGGGGGATCCGGTAATGGTTCTGGCCATTACCGCCTTGGTGGAAGCCCGTCTCTGGCAG
TTGCTGGCCCAGCCGGAAGCGCTGGATCCCTTGCGGGGGCCCTTTACCCCAACAGAGCTGGAGAGCCTTTGCGAAGCCAA
CGAGCAGGCTGCTGCTCGAGAATCGCTGCAATCTCATTTGGTCGATTGGCGGACAGGCCGGGAACGGGCGGCCCAAGAGT
GGATCGAAGAGCTGCTGACCGAAGCTTGGCGTATTGGCCAACCTCAAGGCTTGGGCTGTTTTCTAGCTCCCTTGCAAACT
CTGCTCCACCAGGGCAATGAGGCCCAACGCTGGCTGAAGCAAGTCAACCAGGGATCCACACCTGCCCAGGTGTACCAACA
GGCCATCCAGGAGCTGGCCGAACAAGACCGAGAGAGGCAGGAAACCCTCTGTCAAGCTGTCGGCTAA

Upstream 100 bases:

>100_bases
GCCAAACCCCAGGACAATGAGGGGAGAAGAGAAAGGTTAGACTGGTGAGGCTGCGGCTGGAGGCTGGCCTGTGCTGTTAA
CCAAGGGCTTTGAGGTGGAA

Downstream 100 bases:

>100_bases
GCCTCTGCCCAACGGTGAGCGTTCTCAACCCGGTGCTTTCTACACACTAGCTCGCCGAGCCAACTTATAGTCATTTCAAA
CTGGATTGAGACACTCCTAC

Product: glutamate--cysteine ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MYTGTAAGEVVGLSDRICQALPGFVREPDRRNVEYITPPLRRYEDLLCALLRPRLQLRQFLRRLGPYTLLPGSTLALGGS
DHFERSDPGNPYHDYIERTYGTRVVTASIHINVGLPGTEAIFRACRLLRAEASLYLALSASSPFLDGRVTGSHSSRWQVF
PKTPAQVPFFRDHAHYIAWIQEQLALGTMQNVRHLWASVRPNGPERPYHLNRVELRICDLVGDPVMVLAITALVEARLWQ
LLAQPEALDPLRGPFTPTELESLCEANEQAAARESLQSHLVDWRTGRERAAQEWIEELLTEAWRIGQPQGLGCFLAPLQT
LLHQGNEAQRWLKQVNQGSTPAQVYQQAIQELAEQDRERQETLCQAVG

Sequences:

>Translated_368_residues
MYTGTAAGEVVGLSDRICQALPGFVREPDRRNVEYITPPLRRYEDLLCALLRPRLQLRQFLRRLGPYTLLPGSTLALGGS
DHFERSDPGNPYHDYIERTYGTRVVTASIHINVGLPGTEAIFRACRLLRAEASLYLALSASSPFLDGRVTGSHSSRWQVF
PKTPAQVPFFRDHAHYIAWIQEQLALGTMQNVRHLWASVRPNGPERPYHLNRVELRICDLVGDPVMVLAITALVEARLWQ
LLAQPEALDPLRGPFTPTELESLCEANEQAAARESLQSHLVDWRTGRERAAQEWIEELLTEAWRIGQPQGLGCFLAPLQT
LLHQGNEAQRWLKQVNQGSTPAQVYQQAIQELAEQDRERQETLCQAVG
>Mature_368_residues
MYTGTAAGEVVGLSDRICQALPGFVREPDRRNVEYITPPLRRYEDLLCALLRPRLQLRQFLRRLGPYTLLPGSTLALGGS
DHFERSDPGNPYHDYIERTYGTRVVTASIHINVGLPGTEAIFRACRLLRAEASLYLALSASSPFLDGRVTGSHSSRWQVF
PKTPAQVPFFRDHAHYIAWIQEQLALGTMQNVRHLWASVRPNGPERPYHLNRVELRICDLVGDPVMVLAITALVEARLWQ
LLAQPEALDPLRGPFTPTELESLCEANEQAAARESLQSHLVDWRTGRERAAQEWIEELLTEAWRIGQPQGLGCFLAPLQT
LLHQGNEAQRWLKQVNQGSTPAQVYQQAIQELAEQDRERQETLCQAVG

Specific function: ATP-dependent carboxylate-amine ligase [H]

COG id: COG2170

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carboxylate-amine ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011793
- InterPro:   IPR006336 [H]

Pfam domain/function: PF04107 GCS2 [H]

EC number: NA

Molecular weight: Translated: 41525; Mature: 41525

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTGTAAGEVVGLSDRICQALPGFVREPDRRNVEYITPPLRRYEDLLCALLRPRLQLRQF
CCCCCCCCCEECCHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LRRLGPYTLLPGSTLALGGSDHFERSDPGNPYHDYIERTYGTRVVTASIHINVGLPGTEA
HHHHCCEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEEEEEECCCCHHH
IFRACRLLRAEASLYLALSASSPFLDGRVTGSHSSRWQVFPKTPAQVPFFRDHAHYIAWI
HHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCCCEEECCCCCCCCCCHHHHHHHHHHH
QEQLALGTMQNVRHLWASVRPNGPERPYHLNRVELRICDLVGDPVMVLAITALVEARLWQ
HHHHHHHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LLAQPEALDPLRGPFTPTELESLCEANEQAAARESLQSHLVDWRTGRERAAQEWIEELLT
HHHCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
EAWRIGQPQGLGCFLAPLQTLLHQGNEAQRWLKQVNQGSTPAQVYQQAIQELAEQDRERQ
HHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ETLCQAVG
HHHHHHCC
>Mature Secondary Structure
MYTGTAAGEVVGLSDRICQALPGFVREPDRRNVEYITPPLRRYEDLLCALLRPRLQLRQF
CCCCCCCCCEECCHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LRRLGPYTLLPGSTLALGGSDHFERSDPGNPYHDYIERTYGTRVVTASIHINVGLPGTEA
HHHHCCEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEEEEEECCCCHHH
IFRACRLLRAEASLYLALSASSPFLDGRVTGSHSSRWQVFPKTPAQVPFFRDHAHYIAWI
HHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCCCEEECCCCCCCCCCHHHHHHHHHHH
QEQLALGTMQNVRHLWASVRPNGPERPYHLNRVELRICDLVGDPVMVLAITALVEARLWQ
HHHHHHHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LLAQPEALDPLRGPFTPTELESLCEANEQAAARESLQSHLVDWRTGRERAAQEWIEELLT
HHHCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
EAWRIGQPQGLGCFLAPLQTLLHQGNEAQRWLKQVNQGSTPAQVYQQAIQELAEQDRERQ
HHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ETLCQAVG
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14621292 [H]