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The map label for this gene is grxC [C]

Identifier: 86607627

GI number: 86607627

Start: 136913

End: 137173

Strand: Reverse

Name: grxC [C]

Synonym: CYB_0125

Alternate gene names: 86607627

Gene position: 137173-136913 (Counterclockwise)

Preceding gene: 86607628

Following gene: 86607624

Centisome position: 4.5

GC content: 57.09

Gene sequence:

>261_bases
ATGACTGTTGAGATTTACACCTGGCGTTTTTGTCCCTTCTGCATCCGGGCTAAGCAACTGCTGGATCGCAAAGGCGTGAA
GTATATCGAGTACGCCATCGATGGAGACGAGGCAGCACGGGCGGAAATGGCCAAGCGGGCCAACGGCCGCCGTTCGGTGC
CGCAAATTTTCATCAACGACCAGCATATCGGCGGCTGCGACGATCTTTACGCGCTAGAGGCTCGCGGCCAGTTGGATCTG
CTCCTACAGCAGGCCAGCTAA

Upstream 100 bases:

>100_bases
CCAACTAGACCATGGGAGGCAGAAAACCCCAGGTTTGCAAGGAAAGGGATCCCGGCTCCGTGAAAATGTTAAGCTATGTA
AAAGCGTTTGTTGTTTTCTT

Downstream 100 bases:

>100_bases
GCCTCAACTGTATCTCTCATCACTTTGTAGCCTGTTTAACTTGAGCGCGAGCCTGCTTCACCATGGCAATTAAGGTTTGA
TGGGCGTCCTCGGAGTCCCG

Product: glutaredoxin 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 86; Mature: 85

Protein sequence:

>86_residues
MTVEIYTWRFCPFCIRAKQLLDRKGVKYIEYAIDGDEAARAEMAKRANGRRSVPQIFINDQHIGGCDDLYALEARGQLDL
LLQQAS

Sequences:

>Translated_86_residues
MTVEIYTWRFCPFCIRAKQLLDRKGVKYIEYAIDGDEAARAEMAKRANGRRSVPQIFINDQHIGGCDDLYALEARGQLDL
LLQQAS
>Mature_85_residues
TVEIYTWRFCPFCIRAKQLLDRKGVKYIEYAIDGDEAARAEMAKRANGRRSVPQIFINDQHIGGCDDLYALEARGQLDLL
LQQAS

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=82, Percent_Identity=64.6341463414634, Blast_Score=107, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9836; Mature: 9705

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVEIYTWRFCPFCIRAKQLLDRKGVKYIEYAIDGDEAARAEMAKRANGRRSVPQIFIND
CEEEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCEEEECC
QHIGGCDDLYALEARGQLDLLLQQAS
CCCCCCCCEEEECCCCCEEEEEECCC
>Mature Secondary Structure 
TVEIYTWRFCPFCIRAKQLLDRKGVKYIEYAIDGDEAARAEMAKRANGRRSVPQIFIND
EEEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCEEEECC
QHIGGCDDLYALEARGQLDLLLQQAS
CCCCCCCCEEEECCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]