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The map label for this gene is xerC

Identifier: 85859268

GI number: 85859268

Start: 1455148

End: 1456080

Strand: Direct

Name: xerC

Synonym: SYN_02151

Alternate gene names: 85859268

Gene position: 1455148-1456080 (Clockwise)

Preceding gene: 85859267

Following gene: 85859269

Centisome position: 45.77

GC content: 46.41

Gene sequence:

>933_bases
ATGGATGAGCTAATCAAAGAATTTGATCGTTACATGGACTTGGAGAGAAATCTCTCAACGCACACACGAAAAAATTATTT
AAGCGACTTAAATCAATTCAAAATATATCTTGAAGAAAATCATCGTGTTCCAACCGAATTAAAAACAGAGGCCTGGCAGA
ATGTAGATTATATGATGGTAAGAGCGTTTCTTGGGGCTCTCTATCGGCGCAGAGTCAAGAAAGTGACGATAGCCCGGAAA
CTGGCTTCTCTTAGAGCTTTTTTCAAATATCTGCATCAGAAGAGAAAAATTCAATGCAATCCACTGGAAGCCGTTTCGAC
TCCTCGGACGGAAAAGTATATTCCCGCAGTTCTTTCAGTTGATGAAATCTTTGTCCTGCTGAATCTTCCTTTCCCGGAGG
ATGTTTTTGGCTTGAGGGATCGAGCGATTCTGGAGCTCTTTTATTCCAGCGGCATTCGAGTCAGTGAGCTGACAGGAATC
AATGAGGAGGATATGGATTTTTCTCAGGGACTGATCAGAATCCGCGGTAAAGGGAAAAAAGAGAGGATTGTACCCATAGG
CCAACCGGCAAGTGAGGCTGTCCAGCGCTATATGATGAAAAAACCTGGGAGTGAAACGTCGGGAAAGGCGGTCGCTACTT
GTCCCGTACCCCTGTTTGTGAATCGCAGGCAAGGGCGGTTATCTGCACGCAGTGTGGCGAGAATTTTGAGCAAATACGTT
TCCATGAGCGGTCTTCAAAAGCAAATCAGTCCCCATACGCTGCGACACAGCTTCGCCACCCATCTTATGGATGCAGGGGC
TGATCTGCGGTCTATTCAAGAGCTTCTTGGCCATGAAAGTTTGTCGACAACTCAGAAATATACCGCAGTCAGTGTGAACA
GGCTGATGGCCGTCTATGACAGGGCTCATCCAAAGGCCCGGGGAGGTCACTGA

Upstream 100 bases:

>100_bases
GCTGCAGGCAGTTCATAAAACCATATGGTCAGTGAGCCCGTTGATTATTGATGAATAGATCTTTTACGGGAAAATTGATA
AAGACTCCTTGAGGCGATGA

Downstream 100 bases:

>100_bases
AAGAAAAATGCAGAAAATGAGAGGGACAACCATAGTTGCGGTTAAGCACAAAGGTAAAGTCACGGTGGCCGGTGACGGGC
AGGTCACTCTGGACGTGACG

Product: integrase/recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MDELIKEFDRYMDLERNLSTHTRKNYLSDLNQFKIYLEENHRVPTELKTEAWQNVDYMMVRAFLGALYRRRVKKVTIARK
LASLRAFFKYLHQKRKIQCNPLEAVSTPRTEKYIPAVLSVDEIFVLLNLPFPEDVFGLRDRAILELFYSSGIRVSELTGI
NEEDMDFSQGLIRIRGKGKKERIVPIGQPASEAVQRYMMKKPGSETSGKAVATCPVPLFVNRRQGRLSARSVARILSKYV
SMSGLQKQISPHTLRHSFATHLMDAGADLRSIQELLGHESLSTTQKYTAVSVNRLMAVYDRAHPKARGGH

Sequences:

>Translated_310_residues
MDELIKEFDRYMDLERNLSTHTRKNYLSDLNQFKIYLEENHRVPTELKTEAWQNVDYMMVRAFLGALYRRRVKKVTIARK
LASLRAFFKYLHQKRKIQCNPLEAVSTPRTEKYIPAVLSVDEIFVLLNLPFPEDVFGLRDRAILELFYSSGIRVSELTGI
NEEDMDFSQGLIRIRGKGKKERIVPIGQPASEAVQRYMMKKPGSETSGKAVATCPVPLFVNRRQGRLSARSVARILSKYV
SMSGLQKQISPHTLRHSFATHLMDAGADLRSIQELLGHESLSTTQKYTAVSVNRLMAVYDRAHPKARGGH
>Mature_310_residues
MDELIKEFDRYMDLERNLSTHTRKNYLSDLNQFKIYLEENHRVPTELKTEAWQNVDYMMVRAFLGALYRRRVKKVTIARK
LASLRAFFKYLHQKRKIQCNPLEAVSTPRTEKYIPAVLSVDEIFVLLNLPFPEDVFGLRDRAILELFYSSGIRVSELTGI
NEEDMDFSQGLIRIRGKGKKERIVPIGQPASEAVQRYMMKKPGSETSGKAVATCPVPLFVNRRQGRLSARSVARILSKYV
SMSGLQKQISPHTLRHSFATHLMDAGADLRSIQELLGHESLSTTQKYTAVSVNRLMAVYDRAHPKARGGH

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1790244, Length=307, Percent_Identity=35.8306188925081, Blast_Score=207, Evalue=6e-55,
Organism=Escherichia coli, GI1789261, Length=303, Percent_Identity=33.6633663366337, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1790768, Length=166, Percent_Identity=32.5301204819277, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790767, Length=173, Percent_Identity=28.3236994219653, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC_SYNAS (Q2LT92)

Other databases:

- EMBL:   CP000252
- RefSeq:   YP_461470.1
- ProteinModelPortal:   Q2LT92
- SMR:   Q2LT92
- STRING:   Q2LT92
- GeneID:   3884301
- GenomeReviews:   CP000252_GR
- KEGG:   sat:SYN_02151
- NMPDR:   fig|56780.10.peg.1408
- eggNOG:   COG4974
- HOGENOM:   HBG727654
- OMA:   VEAYSER
- PhylomeDB:   Q2LT92
- BioCyc:   SACI56780:SYN_02151-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 35545; Mature: 35545

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: NA

Important sites: ACT_SITE 153-153 ACT_SITE 177-177 ACT_SITE 252-252 ACT_SITE 255-255 ACT_SITE 278-278 ACT_SITE 287-287

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDELIKEFDRYMDLERNLSTHTRKNYLSDLNQFKIYLEENHRVPTELKTEAWQNVDYMMV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHCCHHHHHH
RAFLGALYRRRVKKVTIARKLASLRAFFKYLHQKRKIQCNPLEAVSTPRTEKYIPAVLSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHH
DEIFVLLNLPFPEDVFGLRDRAILELFYSSGIRVSELTGINEEDMDFSQGLIRIRGKGKK
HHEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEHHCCCCCCCCCHHHCCEEEECCCCC
ERIVPIGQPASEAVQRYMMKKPGSETSGKAVATCPVPLFVNRRQGRLSARSVARILSKYV
CCEEECCCCHHHHHHHHHHHCCCCCCCCCEEEECCCHHEECCCCCCHHHHHHHHHHHHHH
SMSGLQKQISPHTLRHSFATHLMDAGADLRSIQELLGHESLSTTQKYTAVSVNRLMAVYD
HHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RAHPKARGGH
HCCCCCCCCC
>Mature Secondary Structure
MDELIKEFDRYMDLERNLSTHTRKNYLSDLNQFKIYLEENHRVPTELKTEAWQNVDYMMV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHCCHHHHHH
RAFLGALYRRRVKKVTIARKLASLRAFFKYLHQKRKIQCNPLEAVSTPRTEKYIPAVLSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHH
DEIFVLLNLPFPEDVFGLRDRAILELFYSSGIRVSELTGINEEDMDFSQGLIRIRGKGKK
HHEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEHHCCCCCCCCCHHHCCEEEECCCCC
ERIVPIGQPASEAVQRYMMKKPGSETSGKAVATCPVPLFVNRRQGRLSARSVARILSKYV
CCEEECCCCHHHHHHHHHHHCCCCCCCCCEEEECCCHHEECCCCCCHHHHHHHHHHHHHH
SMSGLQKQISPHTLRHSFATHLMDAGADLRSIQELLGHESLSTTQKYTAVSVNRLMAVYD
HHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RAHPKARGGH
HCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA