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The map label for this gene is fabH [H]

Identifier: 85858223

GI number: 85858223

Start: 376499

End: 377506

Strand: Direct

Name: fabH [H]

Synonym: SYN_01149

Alternate gene names: 85858223

Gene position: 376499-377506 (Clockwise)

Preceding gene: 85858222

Following gene: 85858224

Centisome position: 11.84

GC content: 52.08

Gene sequence:

>1008_bases
ATGGATATTGGCATCCTGGCTGAGGCCTATTACCTCCCGCCGAGCAAAAAAAAGGTTCAGGACATATTGGACGCAGAGAA
CATTCCTTTCGGGACCTTCGCAAAAAATGTCGATTTCCGGCGTGACATAGGAATTGAAGAGGTCCACGTCACGGACGAAA
TGCCTTCGGAAGTGGCTGTGAAAACCGCAAAAAACGTTATTTCGAAAAGCGGGATATCCGGGAGTGAAATCGACCTCATC
ATTGATTTCACGAGTCTTCCTCAGGATTACATCGGTCCGACATGGTCGGCGGCCGGGCTTGTTCAGGAAGCGATCGGCGC
GGATCGGGCTTTCTGCACGGCGCTCACGGTGGGGGGCTGCGCCAGTTATCATTTCGCGATGCGATCGGCCCTTGCCCTGA
TGCGCAGTGACGAAAAGATCAATACGGTTCTTCTGGTCGCGGGAGACAGAACCCCCGACCTCAACAAAACCTATTATCCC
ATAACCGTGGCCAGTGATGGAGGAGGGGCCCTGATTCTGAAAAAGGGATGCGACCGGGCCGTCATACTGGGCATTGAAAC
CATTTCGATCGGACGCCTGCACGACGTGTGGTATGTCCCGGGGCTGGGCAGGAAAAAGCCGGATGAAGAGGCATCGGAAA
CCCTGATCCATATGTACTGCAATATGAAAAAGTTCAATGAAGGAGTCATCATCAGGAATTTTTTCATGTTCAGGAAAGTC
ATCAACAAGCTGTTGAGCAGGATCGGCATGACCATGGATGACATCGATTATTTTGTTTATCCGACCTTCTCGACATGGGA
TCAGAAGTACTTTTGTGAAGCCTTGAATATTCCCCGGGAAAAAGTATCGACAGAGGGACTCCGTCACCGGGGACATGTTC
AGGAAAGCGACATGGTGATCAATTATGCCCGCGCTGTGGAAGACGGCGCCATCAAAAAGGGCGACATCGTCATGGTGGTT
TCCAACGGTGCGGGTTTCGCGTGGTCCGCGGTCGTCGTCAGGCATTAG

Upstream 100 bases:

>100_bases
TGGGCGGATGAGGGAATTCGGGCTCGTGTGTTCCCATGGGTGGGGACATTCGAGTGGAGCAATGCTGATTAAATGACCAC
GTGAATGAAGAGGAACGGAT

Downstream 100 bases:

>100_bases
GGTGGGCGCATCGGGTTCAGACGCCCCTATCCGGAAGTGAAAAGCGAGAGAAAGGAACTCAGCGATGTTTGAGTATACTC
GCATGAGACTGATGCAGGCC

Product: 3-oxoacyl-[acyl-carrier-protein] synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MDIGILAEAYYLPPSKKKVQDILDAENIPFGTFAKNVDFRRDIGIEEVHVTDEMPSEVAVKTAKNVISKSGISGSEIDLI
IDFTSLPQDYIGPTWSAAGLVQEAIGADRAFCTALTVGGCASYHFAMRSALALMRSDEKINTVLLVAGDRTPDLNKTYYP
ITVASDGGGALILKKGCDRAVILGIETISIGRLHDVWYVPGLGRKKPDEEASETLIHMYCNMKKFNEGVIIRNFFMFRKV
INKLLSRIGMTMDDIDYFVYPTFSTWDQKYFCEALNIPREKVSTEGLRHRGHVQESDMVINYARAVEDGAIKKGDIVMVV
SNGAGFAWSAVVVRH

Sequences:

>Translated_335_residues
MDIGILAEAYYLPPSKKKVQDILDAENIPFGTFAKNVDFRRDIGIEEVHVTDEMPSEVAVKTAKNVISKSGISGSEIDLI
IDFTSLPQDYIGPTWSAAGLVQEAIGADRAFCTALTVGGCASYHFAMRSALALMRSDEKINTVLLVAGDRTPDLNKTYYP
ITVASDGGGALILKKGCDRAVILGIETISIGRLHDVWYVPGLGRKKPDEEASETLIHMYCNMKKFNEGVIIRNFFMFRKV
INKLLSRIGMTMDDIDYFVYPTFSTWDQKYFCEALNIPREKVSTEGLRHRGHVQESDMVINYARAVEDGAIKKGDIVMVV
SNGAGFAWSAVVVRH
>Mature_335_residues
MDIGILAEAYYLPPSKKKVQDILDAENIPFGTFAKNVDFRRDIGIEEVHVTDEMPSEVAVKTAKNVISKSGISGSEIDLI
IDFTSLPQDYIGPTWSAAGLVQEAIGADRAFCTALTVGGCASYHFAMRSALALMRSDEKINTVLLVAGDRTPDLNKTYYP
ITVASDGGGALILKKGCDRAVILGIETISIGRLHDVWYVPGLGRKKPDEEASETLIHMYCNMKKFNEGVIIRNFFMFRKV
INKLLSRIGMTMDDIDYFVYPTFSTWDQKYFCEALNIPREKVSTEGLRHRGHVQESDMVINYARAVEDGAIKKGDIVMVV
SNGAGFAWSAVVVRH

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 37089; Mature: 37089

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIGILAEAYYLPPSKKKVQDILDAENIPFGTFAKNVDFRRDIGIEEVHVTDEMPSEVAV
CCCEEEEEEEECCCCHHHHHHHHCCCCCCCCHHHCCCCHHHCCCCEEEEECCCCCHHHHH
KTAKNVISKSGISGSEIDLIIDFTSLPQDYIGPTWSAAGLVQEAIGADRAFCTALTVGGC
HHHHHHHHHCCCCCCCEEEEEEECCCCHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHCCH
ASYHFAMRSALALMRSDEKINTVLLVAGDRTPDLNKTYYPITVASDGGGALILKKGCDRA
HHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEEEEECCCCCEEEEECCCCEE
VILGIETISIGRLHDVWYVPGLGRKKPDEEASETLIHMYCNMKKFNEGVIIRNFFMFRKV
EEEEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCHHHCCCCEEEHHHHHHHHH
INKLLSRIGMTMDDIDYFVYPTFSTWDQKYFCEALNIPREKVSTEGLRHRGHVQESDMVI
HHHHHHHHCCCHHCCCEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHH
NYARAVEDGAIKKGDIVMVVSNGAGFAWSAVVVRH
HHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEEEC
>Mature Secondary Structure
MDIGILAEAYYLPPSKKKVQDILDAENIPFGTFAKNVDFRRDIGIEEVHVTDEMPSEVAV
CCCEEEEEEEECCCCHHHHHHHHCCCCCCCCHHHCCCCHHHCCCCEEEEECCCCCHHHHH
KTAKNVISKSGISGSEIDLIIDFTSLPQDYIGPTWSAAGLVQEAIGADRAFCTALTVGGC
HHHHHHHHHCCCCCCCEEEEEEECCCCHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHCCH
ASYHFAMRSALALMRSDEKINTVLLVAGDRTPDLNKTYYPITVASDGGGALILKKGCDRA
HHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEEEEECCCCCEEEEECCCCEE
VILGIETISIGRLHDVWYVPGLGRKKPDEEASETLIHMYCNMKKFNEGVIIRNFFMFRKV
EEEEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCHHHCCCCEEEHHHHHHHHH
INKLLSRIGMTMDDIDYFVYPTFSTWDQKYFCEALNIPREKVSTEGLRHRGHVQESDMVI
HHHHHHHHCCCHHCCCEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHH
NYARAVEDGAIKKGDIVMVVSNGAGFAWSAVVVRH
HHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA