Click here to switch to the map view.

The map label for this gene is fabH [H]

Identifier: 85858222

GI number: 85858222

Start: 375464

End: 376474

Strand: Direct

Name: fabH [H]

Synonym: SYN_01150

Alternate gene names: 85858222

Gene position: 375464-376474 (Clockwise)

Preceding gene: 85858221

Following gene: 85858223

Centisome position: 11.81

GC content: 55.39

Gene sequence:

>1011_bases
ATGACTGACAAGAAGAGCGTCTCATCATCAGCCGTGGGCATCGTCGCGATGGCCTGCTGTTTTCCGGAAAAGATTCTGCC
GATAAGCGAGATCTGCCTGCAGGAAGGGATCGACCCCGACTTCATCCTTGAAAATGAACTCGATATCGGACAGGTCCGTG
TTTTTGAAGGGGAGTGGCGGTCGGATCCGGCGGTTGCCGCGGCGAAGGAGTGCCTGTCACGGGCCGGCCTGAAGCCGACG
GATATCGATGTGATCGTTGACTTCTCCGTTCTGCCGCAGGATTACGTGGTCCCCGCCTGGAGCATGAGCAATAAAATTCA
GTATGATATCGGGGCCGAGCACGCATTCAATATCGGATTCGGCGGCGGAGGCGTCACGAATCTGCTGGCAGCCTTCAAGT
TCGTGTCGGCGCTGATCAAGGCCGATGACGGCGTCAGAACCGCGCTGCTGATTGCCAGTGATGTATCCATCCCCCGGAAC
AGGGTCATCAATCCCGATCAGCCCATGACGATCCTCGGCGATGGCGCGAGCGCCCTGATCGTGTCCGACAGCGCGGACGT
TCTGGAAATCCTTGAAACCGAAATTTCTTCCGACAGCTCCAGGCACGATGTCTTCAACATCCCCGGCGGCGGTCTGGCAC
ATCCGGACCGTATCGATCTGTATCGGGTGAAGATCGATCCCCTCAAATATTCGGTCTCTTCCTCTTTCGACGCCCTGAAG
CAGCTGAGCCGCAAGGCCGCTGATCTGGCAGGAATATCTCTTGATGAAGTGAATCATTTCATCGGACCGAATATCTCCGG
AAAAGATCAATCCCGGTTTGCAGAACTGTTTCATCTTTCCGACGCCGATCCGTTTGGAAAGAACAGGCGGCAGTATGGAC
ACGTGCAGGCAACGGATCTTGTAATCAATCTCTCGGATTTTCTGGAGAAGCAGGCTGGGCGGATGAGGGAATTCGGGCTC
GTGTGTTCCCATGGGTGGGGACATTCGAGTGGAGCAATGCTGATTAAATGA

Upstream 100 bases:

>100_bases
CGCGGAGTTCATCGGCAAGAAGCAGGCGGGTTGACCCAAAACCGGGCGGATTTCGATCCTCTCCGCAGCCGAAGAAAATT
AAACTCTATGGGTACATATC

Downstream 100 bases:

>100_bases
CCACGTGAATGAAGAGGAACGGATATGGATATTGGCATCCTGGCTGAGGCCTATTACCTCCCGCCGAGCAAAAAAAAGGT
TCAGGACATATTGGACGCAG

Product: 3-oxoacyl-[acyl-carrier-protein] synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTDKKSVSSSAVGIVAMACCFPEKILPISEICLQEGIDPDFILENELDIGQVRVFEGEWRSDPAVAAAKECLSRAGLKPT
DIDVIVDFSVLPQDYVVPAWSMSNKIQYDIGAEHAFNIGFGGGGVTNLLAAFKFVSALIKADDGVRTALLIASDVSIPRN
RVINPDQPMTILGDGASALIVSDSADVLEILETEISSDSSRHDVFNIPGGGLAHPDRIDLYRVKIDPLKYSVSSSFDALK
QLSRKAADLAGISLDEVNHFIGPNISGKDQSRFAELFHLSDADPFGKNRRQYGHVQATDLVINLSDFLEKQAGRMREFGL
VCSHGWGHSSGAMLIK

Sequences:

>Translated_336_residues
MTDKKSVSSSAVGIVAMACCFPEKILPISEICLQEGIDPDFILENELDIGQVRVFEGEWRSDPAVAAAKECLSRAGLKPT
DIDVIVDFSVLPQDYVVPAWSMSNKIQYDIGAEHAFNIGFGGGGVTNLLAAFKFVSALIKADDGVRTALLIASDVSIPRN
RVINPDQPMTILGDGASALIVSDSADVLEILETEISSDSSRHDVFNIPGGGLAHPDRIDLYRVKIDPLKYSVSSSFDALK
QLSRKAADLAGISLDEVNHFIGPNISGKDQSRFAELFHLSDADPFGKNRRQYGHVQATDLVINLSDFLEKQAGRMREFGL
VCSHGWGHSSGAMLIK
>Mature_335_residues
TDKKSVSSSAVGIVAMACCFPEKILPISEICLQEGIDPDFILENELDIGQVRVFEGEWRSDPAVAAAKECLSRAGLKPTD
IDVIVDFSVLPQDYVVPAWSMSNKIQYDIGAEHAFNIGFGGGGVTNLLAAFKFVSALIKADDGVRTALLIASDVSIPRNR
VINPDQPMTILGDGASALIVSDSADVLEILETEISSDSSRHDVFNIPGGGLAHPDRIDLYRVKIDPLKYSVSSSFDALKQ
LSRKAADLAGISLDEVNHFIGPNISGKDQSRFAELFHLSDADPFGKNRRQYGHVQATDLVINLSDFLEKQAGRMREFGLV
CSHGWGHSSGAMLIK

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 36349; Mature: 36217

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKKSVSSSAVGIVAMACCFPEKILPISEICLQEGIDPDFILENELDIGQVRVFEGEWR
CCCCCCCCHHHHHHHHHHHHCCHHCCCHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCC
SDPAVAAAKECLSRAGLKPTDIDVIVDFSVLPQDYVVPAWSMSNKIQYDIGAEHAFNIGF
CCHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCEECCCCCCCEEEEECCCCEEEEEEC
GGGGVTNLLAAFKFVSALIKADDGVRTALLIASDVSIPRNRVINPDQPMTILGDGASALI
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEECCCEEEE
VSDSADVLEILETEISSDSSRHDVFNIPGGGLAHPDRIDLYRVKIDPLKYSVSSSFDALK
EECCHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCEEEEEEEECCEEEEHHHHHHHHH
QLSRKAADLAGISLDEVNHFIGPNISGKDQSRFAELFHLSDADPFGKNRRQYGHVQATDL
HHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHCCCEEEEHE
VINLSDFLEKQAGRMREFGLVCSHGWGHSSGAMLIK
EEEHHHHHHHHHHHHHHHCCEEECCCCCCCCCEEEC
>Mature Secondary Structure 
TDKKSVSSSAVGIVAMACCFPEKILPISEICLQEGIDPDFILENELDIGQVRVFEGEWR
CCCCCCCHHHHHHHHHHHHCCHHCCCHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCC
SDPAVAAAKECLSRAGLKPTDIDVIVDFSVLPQDYVVPAWSMSNKIQYDIGAEHAFNIGF
CCHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCEECCCCCCCEEEEECCCCEEEEEEC
GGGGVTNLLAAFKFVSALIKADDGVRTALLIASDVSIPRNRVINPDQPMTILGDGASALI
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEECCCEEEE
VSDSADVLEILETEISSDSSRHDVFNIPGGGLAHPDRIDLYRVKIDPLKYSVSSSFDALK
EECCHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCEEEEEEEECCEEEEHHHHHHHHH
QLSRKAADLAGISLDEVNHFIGPNISGKDQSRFAELFHLSDADPFGKNRRQYGHVQATDL
HHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHCCCEEEEHE
VINLSDFLEKQAGRMREFGLVCSHGWGHSSGAMLIK
EEEHHHHHHHHHHHHHHHCCEEECCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]