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The map label for this gene is queC

Identifier: 85375614

GI number: 85375614

Start: 2808243

End: 2808962

Strand: Direct

Name: queC

Synonym: ELI_13935

Alternate gene names: 85375614

Gene position: 2808243-2808962 (Clockwise)

Preceding gene: 85375613

Following gene: 85375615

Centisome position: 92.0

GC content: 64.31

Gene sequence:

>720_bases
ATGGCAGCAAATTCCCGCAAGGCAGCCGCGATCCTCTTGTCCGGCGGCCTCGACTCCATGGTCACCGCCGCGATCGCGCA
GGAGCAGGGCTACGCCGTGCATGCGCTGACGATCGATTATGGCCAGCGCCACAAGGTCGAGCTGCAGTCTGCCCGGTTGA
TTGCCGCGAAGATCGGGGCCGAGCGACATGTCGAAATCGAGGCCGATCTGCGGGCGCTGGGTGGATCGGCGCTGACCGAT
GATATCGACGTTCCCAAATGCGGCGTCGGAAACGACATTCCGGTCACCTACGTGCCTGCGCGCAACCTCGTGTTCCTGTC
GTTGACCACGGCTTTTGCGGAAGCGTCCGGCGCGCGGGATATTTTCATCGGGGTGAACGCGCTCGATTATTCCGGTTATC
CGGACTGCCGCCCCGAGTTCATCGAAAGCTTTGCCGTCACGGCCAACCTCGCCACCAAGGCGGGCGTCGAGGAATCGGCG
CCTTTCAAGATCCATGCCCCGCTGCAACACATGACCAAGGCCGATATCGCGCGCGAATGCGCCCGGCTCGGTCTCGAGAG
TGCGTGGAGCTGGTCCTGCTACGACCCGCTGCCCGGCCTCAAGCCTTGCGGCGCGTGCGATTCCTGCCGGTTGCGGCGCA
AGGGATTTGCCGAAGCGGGGCTGGCGGACGGGCTAGACTATCCGGCGGATGCACCGCCGATCCAGGGAGAGAATGCGTGA

Upstream 100 bases:

>100_bases
GGCTTGCCGTTCTCGTTCACTGCGGAAGGTCGCCGGATCGGCGCCTGTCGCTAGTCACTTTGCGCTTGGGCGGCGCGTGA
ACCTGCGCTAGCCCCACTCA

Downstream 100 bases:

>100_bases
ACCAGACCGAGACCCAGCCTGCCGCTGACAATCCGGCCCCCGAGCGCGTGCCTGCCTACAGCTGGTATGCGCTCAGCGTC
CTAGTCATCGTCTATGTCCT

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MAANSRKAAAILLSGGLDSMVTAAIAQEQGYAVHALTIDYGQRHKVELQSARLIAAKIGAERHVEIEADLRALGGSALTD
DIDVPKCGVGNDIPVTYVPARNLVFLSLTTAFAEASGARDIFIGVNALDYSGYPDCRPEFIESFAVTANLATKAGVEESA
PFKIHAPLQHMTKADIARECARLGLESAWSWSCYDPLPGLKPCGACDSCRLRRKGFAEAGLADGLDYPADAPPIQGENA

Sequences:

>Translated_239_residues
MAANSRKAAAILLSGGLDSMVTAAIAQEQGYAVHALTIDYGQRHKVELQSARLIAAKIGAERHVEIEADLRALGGSALTD
DIDVPKCGVGNDIPVTYVPARNLVFLSLTTAFAEASGARDIFIGVNALDYSGYPDCRPEFIESFAVTANLATKAGVEESA
PFKIHAPLQHMTKADIARECARLGLESAWSWSCYDPLPGLKPCGACDSCRLRRKGFAEAGLADGLDYPADAPPIQGENA
>Mature_238_residues
AANSRKAAAILLSGGLDSMVTAAIAQEQGYAVHALTIDYGQRHKVELQSARLIAAKIGAERHVEIEADLRALGGSALTDD
IDVPKCGVGNDIPVTYVPARNLVFLSLTTAFAEASGARDIFIGVNALDYSGYPDCRPEFIESFAVTANLATKAGVEESAP
FKIHAPLQHMTKADIARECARLGLESAWSWSCYDPLPGLKPCGACDSCRLRRKGFAEAGLADGLDYPADAPPIQGENA

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=234, Percent_Identity=36.3247863247863, Blast_Score=124, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_ERYLH (Q2N612)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_459676.1
- ProteinModelPortal:   Q2N612
- SMR:   Q2N612
- STRING:   Q2N612
- GeneID:   3870584
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_13935
- NMPDR:   fig|314225.3.peg.231
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- PhylomeDB:   Q2N612
- BioCyc:   ELIT314225:ELI_13935-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR001518
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11587
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 25290; Mature: 25159

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAANSRKAAAILLSGGLDSMVTAAIAQEQGYAVHALTIDYGQRHKVELQSARLIAAKIGA
CCCCCCCEEEEEEECCHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEHHHHEEEHHHCCC
ERHVEIEADLRALGGSALTDDIDVPKCGVGNDIPVTYVPARNLVFLSLTTAFAEASGARD
CCEEEEEHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEHHHHHHCCCCCE
IFIGVNALDYSGYPDCRPEFIESFAVTANLATKAGVEESAPFKIHAPLQHMTKADIAREC
EEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHH
ARLGLESAWSWSCYDPLPGLKPCGACDSCRLRRKGFAEAGLADGLDYPADAPPIQGENA
HHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AANSRKAAAILLSGGLDSMVTAAIAQEQGYAVHALTIDYGQRHKVELQSARLIAAKIGA
CCCCCCEEEEEEECCHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEHHHHEEEHHHCCC
ERHVEIEADLRALGGSALTDDIDVPKCGVGNDIPVTYVPARNLVFLSLTTAFAEASGARD
CCEEEEEHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEHHHHHHCCCCCE
IFIGVNALDYSGYPDCRPEFIESFAVTANLATKAGVEESAPFKIHAPLQHMTKADIAREC
EEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHH
ARLGLESAWSWSCYDPLPGLKPCGACDSCRLRRKGFAEAGLADGLDYPADAPPIQGENA
HHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA