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The map label for this gene is fbcH [H]

Identifier: 85375556

GI number: 85375556

Start: 2749593

End: 2750444

Strand: Direct

Name: fbcH [H]

Synonym: ELI_13645

Alternate gene names: 85375556

Gene position: 2749593-2750444 (Clockwise)

Preceding gene: 85375555

Following gene: 85375557

Centisome position: 90.08

GC content: 61.74

Gene sequence:

>852_bases
ATGATCCGCCTATTTTCCATCGCTGCCGGGCTGGTGTTCACCCTCGTGGTCATGATCGCCTTCGGCGTCGGCGCCTACAC
CGCCGCGACCGAAGAGGTCGTCAAGGGACCGGAGAAATACTTCCATCTTGAGAACAAGACGCCCGCCGGCGGCTGGTCGT
TCGACGGCCCGCTCGGTCGCTGGGATGTCGCCCAGCTGCAACGCGGCCTGAAGGTCTATGACGAAGTCTGTTCGGCCTGC
CACGGGCTTAAGTTCGTCGCCTTCCGCAACCTCGCCGAAATCGGTTTCGACGAAGGCCAGGTGAAGAATTACGCTGCCGC
CAAACAGGTGCCGGGCATTGATCCGAACACCGGCGAAGCCACTACCCGTGCCGGCCTGCCGACCGATTACTTCCCGGATC
CCTATCCGAACGATGTCGCGGCGGCTGCAGCCAACAATAACGCCATTCCGCCCGATCTTTCGCTGATAACGAAGGCGCGC
AAGGACGGGAGCAATTACGTCTATTCGCTGCTATCGGGCTATGGCGATCCGCCGGCCGAGCTGGCGCAGCAGTTCCCGGA
CTTTAACACCCCGCCGGGGCTCTATTTCAATCGGTACTTCAAGTATCTCAATATCGCGATGCCGCCGCAGCTGACGCCGG
GGCAGGTGACCTATGACGACGGGACCGAAGCCACGGTCGAACAGATGTCGGCAGACGTCGCGGCATTCCTGACCTGGACG
GCGGAGCCCAAGATGCAGCAGCGCAAGCAGACCGGCTGGGCCGTGATCGGCTTCCTGCTCTTCGCCACCATCCTGGCCTA
TCTCGCCAAGCAGCAGATCTGGTCGGCGGTGAAACCGAAGAAGGCCAAATAG

Upstream 100 bases:

>100_bases
GCCCTATTCGATTACCGAGGCGGTGCTTGGCTCCGACAAGAAGGCCGTCCTCGGCGAGAACCCCGCCCCGGCTGAGTAAG
AATCTAGGAAAGACGAAAAC

Downstream 100 bases:

>100_bases
GCCGACTTTCGCGCAGCAACGCAATTGACAGCGCCCCTCCATCCCTGTGATGCGAGGGGCGCTTTGCATTCGAGGGGGCG
GAAATGACGGTCGAGGAACT

Product: cytochrome c1, heme protein precursor

Products: Q; ferrocytochrome c

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MIRLFSIAAGLVFTLVVMIAFGVGAYTAATEEVVKGPEKYFHLENKTPAGGWSFDGPLGRWDVAQLQRGLKVYDEVCSAC
HGLKFVAFRNLAEIGFDEGQVKNYAAAKQVPGIDPNTGEATTRAGLPTDYFPDPYPNDVAAAAANNNAIPPDLSLITKAR
KDGSNYVYSLLSGYGDPPAELAQQFPDFNTPPGLYFNRYFKYLNIAMPPQLTPGQVTYDDGTEATVEQMSADVAAFLTWT
AEPKMQQRKQTGWAVIGFLLFATILAYLAKQQIWSAVKPKKAK

Sequences:

>Translated_283_residues
MIRLFSIAAGLVFTLVVMIAFGVGAYTAATEEVVKGPEKYFHLENKTPAGGWSFDGPLGRWDVAQLQRGLKVYDEVCSAC
HGLKFVAFRNLAEIGFDEGQVKNYAAAKQVPGIDPNTGEATTRAGLPTDYFPDPYPNDVAAAAANNNAIPPDLSLITKAR
KDGSNYVYSLLSGYGDPPAELAQQFPDFNTPPGLYFNRYFKYLNIAMPPQLTPGQVTYDDGTEATVEQMSADVAAFLTWT
AEPKMQQRKQTGWAVIGFLLFATILAYLAKQQIWSAVKPKKAK
>Mature_283_residues
MIRLFSIAAGLVFTLVVMIAFGVGAYTAATEEVVKGPEKYFHLENKTPAGGWSFDGPLGRWDVAQLQRGLKVYDEVCSAC
HGLKFVAFRNLAEIGFDEGQVKNYAAAKQVPGIDPNTGEATTRAGLPTDYFPDPYPNDVAAAAANNNAIPPDLSLITKAR
KDGSNYVYSLLSGYGDPPAELAQQFPDFNTPPGLYFNRYFKYLNIAMPPQLTPGQVTYDDGTEATVEQMSADVAAFLTWT
AEPKMQQRKQTGWAVIGFLLFATILAYLAKQQIWSAVKPKKAK

Specific function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. c1 functions as an electron donor to cytochrome c [H]

COG id: COG2857

COG function: function code C; Cytochrome c1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI21359867, Length=239, Percent_Identity=41.0041841004184, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17506225, Length=251, Percent_Identity=39.4422310756972, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6324639, Length=253, Percent_Identity=41.1067193675889, Blast_Score=183, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24658292, Length=265, Percent_Identity=41.8867924528302, Blast_Score=190, Evalue=8e-49,
Organism=Drosophila melanogaster, GI21358225, Length=231, Percent_Identity=39.8268398268398, Blast_Score=156, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016175
- InterPro:   IPR005798
- InterPro:   IPR005797
- InterPro:   IPR002326
- InterPro:   IPR021157
- InterPro:   IPR009056
- InterPro:   IPR016174 [H]

Pfam domain/function: PF00032 Cytochrom_B_C; PF00033 Cytochrom_B_N; PF02167 Cytochrom_C1 [H]

EC number: 1.10.2.2

Molecular weight: Translated: 30908; Mature: 30908

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLFSIAAGLVFTLVVMIAFGVGAYTAATEEVVKGPEKYFHLENKTPAGGWSFDGPLGR
CEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHEECCCCCCCCCCCCCCCCCC
WDVAQLQRGLKVYDEVCSACHGLKFVAFRNLAEIGFDEGQVKNYAAAKQVPGIDPNTGEA
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCC
TTRAGLPTDYFPDPYPNDVAAAAANNNAIPPDLSLITKARKDGSNYVYSLLSGYGDPPAE
HHCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCHHH
LAQQFPDFNTPPGLYFNRYFKYLNIAMPPQLTPGQVTYDDGTEATVEQMSADVAAFLTWT
HHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCC
AEPKMQQRKQTGWAVIGFLLFATILAYLAKQQIWSAVKPKKAK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIRLFSIAAGLVFTLVVMIAFGVGAYTAATEEVVKGPEKYFHLENKTPAGGWSFDGPLGR
CEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHEECCCCCCCCCCCCCCCCCC
WDVAQLQRGLKVYDEVCSACHGLKFVAFRNLAEIGFDEGQVKNYAAAKQVPGIDPNTGEA
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCC
TTRAGLPTDYFPDPYPNDVAAAAANNNAIPPDLSLITKARKDGSNYVYSLLSGYGDPPAE
HHCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCHHH
LAQQFPDFNTPPGLYFNRYFKYLNIAMPPQLTPGQVTYDDGTEATVEQMSADVAAFLTWT
HHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCC
AEPKMQQRKQTGWAVIGFLLFATILAYLAKQQIWSAVKPKKAK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: QH2; ferricytochrome c

Specific reaction: QH2 + 2 ferricytochrome c = Q + 2 ferrocytochrome c

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2541921; 12597275 [H]