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The map label for this gene is glmM

Identifier: 85374876

GI number: 85374876

Start: 2080314

End: 2081672

Strand: Direct

Name: glmM

Synonym: ELI_10245

Alternate gene names: 85374876

Gene position: 2080314-2081672 (Clockwise)

Preceding gene: 85374873

Following gene: 85374877

Centisome position: 68.15

GC content: 62.69

Gene sequence:

>1359_bases
ATGTCGCAACAGGGACAGGCAGTGGCACGCAAATTCTTCGGCACCGACGGCATCCGTGGTGAAACCAACACAGGCAACAT
GACCCCTGAAATCGCCATGCGCGTGGCGCAGGCTGCGGGTGAGTATTTCCGCCGGGGCGATCATCGCCACCGGGTCGTTA
TCGGTAAGGACACCCGCCTTTCCGGCTATATGATGGAAGCAGCGCTGGTCGCCGGGTTCACCAGTGTCGGGATGGATGTA
ATCCAGACCGGGCCCTTGCCGACCCCGGCGGTCGCGCTTCTGACGAAGGAGATGCGGGCAGATCTCGGCGTGATGATTTC
CGCCAGCCACAACCCCTATCGCGATAACGGGATCAAGCTGTTCGGGCCGGACGGTTTCAAGCTTTCCGACGAGACCGAAC
TGGCCATCGAGCAGGGTATCGTATCCGAACCAGCTTTGGTTCCGGCAGCCGAGATCGGCCGGGCACGCCGCATAGAGGAC
TCGCGCGGCCGCTATATCCACGCGCTGAAGCAATCGGTGTCCGACGAGACGCGTTTCGACAGCCTCAAGGTGGTGGTCGA
TTGCGCGAATGGCGCGGCCTACCAGGTCGCGCCCTCCGCGATCTGGGAATTGGGAGCGGAGATCATCACGCTGGGCGTCA
CGCCCAACGGCACCAACATCAATGATGGCGTCGGCTCGACCTCGCTCGATGCGATCAAGCGTACGGTGGTCGAGGAAGGC
GCAGATATCGGCATCGCGCTCGACGGCGATGCCGACCGGCTGATCGTGATCGACGAGAAAGGCGAAGCTGTCGACGGCGA
CCAGATCATGGGCCTGATCGCAACCAGGATGGCAGAAAAGCAGGCGCTGCGCGGGGGCGGGGTTGTTGCAACCGTTATGA
GCAATCTGGGCCTCGAACGCTATCTCGACAGCAAGAACCTGCGGCTGGAGCGCACGCAGGTCGGCGATCGCTATGTTTTG
GAACGCATGAAGACCGGGGGCTTCAATATCGGCGGCGAGCAGTCCGGGCACATGATCCTGCTCGACCATGCTACGACTGG
CGACGGGACGGTCGCTGCCCTGCGCGTGCTCGCCAGCCTCGTCAATTCCGGCAAGCCCGCGAGCGAAGTCCTGCACGTTT
TCGAGAAAGTGCCGCAATTGCTCAAGAATGTCCGCTACGAAGGCGGGCGACCGCTGGACAAGGACAGCGTTCAGACCGCG
ATCGCGGATGCCGAGAAAGCGCTGGACGGCAAAGGCCGCCTGGTGATCCGCCCGTCGGGCACGGAGCCGGTCATTCGAGT
GATGGCAGAGGGTGACGATGCCGATCAGGTCGAGACTGTGGTCGATCAGATCTGCGACGCCGTGAAAGCCGCCGGCTGA

Upstream 100 bases:

>100_bases
GATTCGGCCAATACCCGGCCCTCCCCTATTCGCCTCTTCCCTTCGCGGGTGCTTAGCGGATAAGGCGCGTGGCAAATCGC
GAGGGTTCTCGCAACCGGTA

Downstream 100 bases:

>100_bases
TGCTGGAAATGCGCCCCGATTGCGAACGCTGCGGGGCCGATCTGCCCGCGCCAGCGCCGGGTGCTTTCATCTGCAGCTTC
GAATGTACTTTCTGCGCCGA

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSQQGQAVARKFFGTDGIRGETNTGNMTPEIAMRVAQAAGEYFRRGDHRHRVVIGKDTRLSGYMMEAALVAGFTSVGMDV
IQTGPLPTPAVALLTKEMRADLGVMISASHNPYRDNGIKLFGPDGFKLSDETELAIEQGIVSEPALVPAAEIGRARRIED
SRGRYIHALKQSVSDETRFDSLKVVVDCANGAAYQVAPSAIWELGAEIITLGVTPNGTNINDGVGSTSLDAIKRTVVEEG
ADIGIALDGDADRLIVIDEKGEAVDGDQIMGLIATRMAEKQALRGGGVVATVMSNLGLERYLDSKNLRLERTQVGDRYVL
ERMKTGGFNIGGEQSGHMILLDHATTGDGTVAALRVLASLVNSGKPASEVLHVFEKVPQLLKNVRYEGGRPLDKDSVQTA
IADAEKALDGKGRLVIRPSGTEPVIRVMAEGDDADQVETVVDQICDAVKAAG

Sequences:

>Translated_452_residues
MSQQGQAVARKFFGTDGIRGETNTGNMTPEIAMRVAQAAGEYFRRGDHRHRVVIGKDTRLSGYMMEAALVAGFTSVGMDV
IQTGPLPTPAVALLTKEMRADLGVMISASHNPYRDNGIKLFGPDGFKLSDETELAIEQGIVSEPALVPAAEIGRARRIED
SRGRYIHALKQSVSDETRFDSLKVVVDCANGAAYQVAPSAIWELGAEIITLGVTPNGTNINDGVGSTSLDAIKRTVVEEG
ADIGIALDGDADRLIVIDEKGEAVDGDQIMGLIATRMAEKQALRGGGVVATVMSNLGLERYLDSKNLRLERTQVGDRYVL
ERMKTGGFNIGGEQSGHMILLDHATTGDGTVAALRVLASLVNSGKPASEVLHVFEKVPQLLKNVRYEGGRPLDKDSVQTA
IADAEKALDGKGRLVIRPSGTEPVIRVMAEGDDADQVETVVDQICDAVKAAG
>Mature_451_residues
SQQGQAVARKFFGTDGIRGETNTGNMTPEIAMRVAQAAGEYFRRGDHRHRVVIGKDTRLSGYMMEAALVAGFTSVGMDVI
QTGPLPTPAVALLTKEMRADLGVMISASHNPYRDNGIKLFGPDGFKLSDETELAIEQGIVSEPALVPAAEIGRARRIEDS
RGRYIHALKQSVSDETRFDSLKVVVDCANGAAYQVAPSAIWELGAEIITLGVTPNGTNINDGVGSTSLDAIKRTVVEEGA
DIGIALDGDADRLIVIDEKGEAVDGDQIMGLIATRMAEKQALRGGGVVATVMSNLGLERYLDSKNLRLERTQVGDRYVLE
RMKTGGFNIGGEQSGHMILLDHATTGDGTVAALRVLASLVNSGKPASEVLHVFEKVPQLLKNVRYEGGRPLDKDSVQTAI
ADAEKALDGKGRLVIRPSGTEPVIRVMAEGDDADQVETVVDQICDAVKAAG

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=443, Percent_Identity=49.8871331828442, Blast_Score=415, Evalue=1e-117,
Organism=Escherichia coli, GI1788361, Length=446, Percent_Identity=27.3542600896861, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_ERYLH (Q2N850)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_458938.1
- ProteinModelPortal:   Q2N850
- SMR:   Q2N850
- STRING:   Q2N850
- GeneID:   3869112
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_10245
- NMPDR:   fig|314225.3.peg.983
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   EEAGINS
- PhylomeDB:   Q2N850
- ProtClustDB:   PRK14315
- BioCyc:   ELIT314225:ELI_10245-MONOMER
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 48163; Mature: 48032

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 109-109

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQGQAVARKFFGTDGIRGETNTGNMTPEIAMRVAQAAGEYFRRGDHRHRVVIGKDTRL
CCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
SGYMMEAALVAGFTSVGMDVIQTGPLPTPAVALLTKEMRADLGVMISASHNPYRDNGIKL
HHHHHHHHHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEE
FGPDGFKLSDETELAIEQGIVSEPALVPAAEIGRARRIEDSRGRYIHALKQSVSDETRFD
ECCCCCEECCCHHHHHHHCCCCCCCCCCHHHHCCHHCCCCCCCHHHHHHHHHHCHHHHHC
SLKVVVDCANGAAYQVAPSAIWELGAEIITLGVTPNGTNINDGVGSTSLDAIKRTVVEEG
CEEEEEEECCCCEEEECHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCC
ADIGIALDGDADRLIVIDEKGEAVDGDQIMGLIATRMAEKQALRGGGVVATVMSNLGLER
CCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHH
YLDSKNLRLERTQVGDRYVLERMKTGGFNIGGEQSGHMILLDHATTGDGTVAALRVLASL
HHCCCCCEEEHHHCCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHH
VNSGKPASEVLHVFEKVPQLLKNVRYEGGRPLDKDSVQTAIADAEKALDGKGRLVIRPSG
HHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCC
TEPVIRVMAEGDDADQVETVVDQICDAVKAAG
CCCEEEEEECCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQQGQAVARKFFGTDGIRGETNTGNMTPEIAMRVAQAAGEYFRRGDHRHRVVIGKDTRL
CCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
SGYMMEAALVAGFTSVGMDVIQTGPLPTPAVALLTKEMRADLGVMISASHNPYRDNGIKL
HHHHHHHHHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEE
FGPDGFKLSDETELAIEQGIVSEPALVPAAEIGRARRIEDSRGRYIHALKQSVSDETRFD
ECCCCCEECCCHHHHHHHCCCCCCCCCCHHHHCCHHCCCCCCCHHHHHHHHHHCHHHHHC
SLKVVVDCANGAAYQVAPSAIWELGAEIITLGVTPNGTNINDGVGSTSLDAIKRTVVEEG
CEEEEEEECCCCEEEECHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCC
ADIGIALDGDADRLIVIDEKGEAVDGDQIMGLIATRMAEKQALRGGGVVATVMSNLGLER
CCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHH
YLDSKNLRLERTQVGDRYVLERMKTGGFNIGGEQSGHMILLDHATTGDGTVAALRVLASL
HHCCCCCEEEHHHCCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHH
VNSGKPASEVLHVFEKVPQLLKNVRYEGGRPLDKDSVQTAIADAEKALDGKGRLVIRPSG
HHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCC
TEPVIRVMAEGDDADQVETVVDQICDAVKAAG
CCCEEEEEECCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA