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The map label for this gene is sodB [H]

Identifier: 85374874

GI number: 85374874

Start: 2078271

End: 2078882

Strand: Reverse

Name: sodB [H]

Synonym: ELI_10235

Alternate gene names: 85374874

Gene position: 2078882-2078271 (Counterclockwise)

Preceding gene: 85374875

Following gene: 85374871

Centisome position: 68.11

GC content: 61.6

Gene sequence:

>612_bases
ATGGCTTTCGAAGTAACCCCGCTGCCCTATGCCGACACCGCGCTGGAACCCGCCGTGTCCGCCAACACTTTGTCCTACCA
CCACGGCAAGCACCACAAGGCGTATGTCGACAAAACCAACGCCGCTATCGAAGGCACCGATCACGCCGACAAGTCGCTCG
CGGAAATCGTCGCGGCGGCGCGCGGCAGCGACCAGGGACTGTTCAACAATGCAGCGCAGAGCTGGAACCACGGCTTCTAC
TGGCATTCGATGACGGGCGACGAGACATATCCGTCGGACGAGCTCAAGAGCATGATCGACGATGCCTTCGGCTCGGTCGA
GGAACTGACTTCGAAACTGCAGGATCGCGGTGCCGGCCACTTTGCCAGCGGCTGGGTCTGGCTCGCCGAAAAAGGCGGCA
AGCTGACGATCGAGGAAACCCATGACGGCGACACGCTGGCCGACCAGGACGGCGTCAACCCGCTGCTCGTGATCGACCTG
TGGGAACACGCCTATTATCTCGATCACCAGAATGCGCGCCCGGCCTATCTGAAGGCGGTGACCGAAGGAAAGCTCAACTG
GAGCTTCGCTTCCGAAAACCTCGCGCGGGGTACGACCTGGTCCTACGCCTGA

Upstream 100 bases:

>100_bases
GCGGTCGACCGTGAAAAATCGGTTTCCATGCAACCCGAGAGCGCCTGATGCGTTCATCTCACAGACACCCCCTTTCACAC
GATCCAACGGGAGATCACCA

Downstream 100 bases:

>100_bases
TCGCTGGATAGCGAACGAAGAAAGGCCCGCCGCTCCAGACTGGAGGGCGGGCCTTTTCCTTGCGTGCGAGAGGGGCAACT
AACGCGTGGGTTCGGATACC

Product: superoxide dismutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MAFEVTPLPYADTALEPAVSANTLSYHHGKHHKAYVDKTNAAIEGTDHADKSLAEIVAAARGSDQGLFNNAAQSWNHGFY
WHSMTGDETYPSDELKSMIDDAFGSVEELTSKLQDRGAGHFASGWVWLAEKGGKLTIEETHDGDTLADQDGVNPLLVIDL
WEHAYYLDHQNARPAYLKAVTEGKLNWSFASENLARGTTWSYA

Sequences:

>Translated_203_residues
MAFEVTPLPYADTALEPAVSANTLSYHHGKHHKAYVDKTNAAIEGTDHADKSLAEIVAAARGSDQGLFNNAAQSWNHGFY
WHSMTGDETYPSDELKSMIDDAFGSVEELTSKLQDRGAGHFASGWVWLAEKGGKLTIEETHDGDTLADQDGVNPLLVIDL
WEHAYYLDHQNARPAYLKAVTEGKLNWSFASENLARGTTWSYA
>Mature_202_residues
AFEVTPLPYADTALEPAVSANTLSYHHGKHHKAYVDKTNAAIEGTDHADKSLAEIVAAARGSDQGLFNNAAQSWNHGFYW
HSMTGDETYPSDELKSMIDDAFGSVEELTSKLQDRGAGHFASGWVWLAEKGGKLTIEETHDGDTLADQDGVNPLLVIDLW
EHAYYLDHQNARPAYLKAVTEGKLNWSFASENLARGTTWSYA

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=191, Percent_Identity=38.2198952879581, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI67782305, Length=191, Percent_Identity=38.2198952879581, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI67782309, Length=188, Percent_Identity=33.5106382978723, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI1787946, Length=199, Percent_Identity=44.7236180904523, Blast_Score=166, Evalue=8e-43,
Organism=Escherichia coli, GI1790342, Length=188, Percent_Identity=35.6382978723404, Blast_Score=119, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17506561, Length=191, Percent_Identity=35.6020942408377, Blast_Score=107, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17569479, Length=191, Percent_Identity=36.6492146596859, Blast_Score=103, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6321796, Length=196, Percent_Identity=32.1428571428571, Blast_Score=95, Evalue=7e-21,
Organism=Drosophila melanogaster, GI17136812, Length=175, Percent_Identity=37.1428571428571, Blast_Score=120, Evalue=7e-28,

Paralogues:

None

Copy number: 2020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 900 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 22343; Mature: 22211

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFEVTPLPYADTALEPAVSANTLSYHHGKHHKAYVDKTNAAIEGTDHADKSLAEIVAAA
CCEECCCCCCCCHHCCCCCCCCEEEECCCCCCEEEEECCCCEECCCCCHHHHHHHHHHHH
RGSDQGLFNNAAQSWNHGFYWHSMTGDETYPSDELKSMIDDAFGSVEELTSKLQDRGAGH
CCCCCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
FASGWVWLAEKGGKLTIEETHDGDTLADQDGVNPLLVIDLWEHAYYLDHQNARPAYLKAV
CCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCEEEECCCCCCHHHHEEE
TEGKLNWSFASENLARGTTWSYA
CCCCCEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
AFEVTPLPYADTALEPAVSANTLSYHHGKHHKAYVDKTNAAIEGTDHADKSLAEIVAAA
CEECCCCCCCCHHCCCCCCCCEEEECCCCCCEEEEECCCCEECCCCCHHHHHHHHHHHH
RGSDQGLFNNAAQSWNHGFYWHSMTGDETYPSDELKSMIDDAFGSVEELTSKLQDRGAGH
CCCCCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
FASGWVWLAEKGGKLTIEETHDGDTLADQDGVNPLLVIDLWEHAYYLDHQNARPAYLKAV
CCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCEEEECCCCCCHHHHEEE
TEGKLNWSFASENLARGTTWSYA
CCCCCEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3542995 [H]