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The map label for this gene is aatC [H]

Identifier: 85374861

GI number: 85374861

Start: 2064297

End: 2065496

Strand: Reverse

Name: aatC [H]

Synonym: ELI_10170

Alternate gene names: 85374861

Gene position: 2065496-2064297 (Counterclockwise)

Preceding gene: 85374868

Following gene: 85374860

Centisome position: 67.67

GC content: 62.25

Gene sequence:

>1200_bases
ATGGACACCGAATTCTACCGGATGAAGCGCTTGCCCCCCTACGTGATCGCTGAAGTCAATGCGATGCGGCACGCGGCACG
CCAGGCGGGAGAAGACATTATCGACCTGGGCATGGGAAACCCCGATCGCCCGCCGCCGCAGCACGTCATCGACAAACTGT
GCGAGGTTGCGCAGAAGCCCGACGCGCACGGCTATTCGCAATCGCGCGGGATTCCCGGCCTCAGGCGAGCGCAGGCGAAT
TACTACGGCAACCGGTTCGGCGTCGATATCGATCCCGAAAGCGAAGTGGTCGTCACGCTCGGTTCGAAGGAAGGGCTCGC
CAGCCTGGCGACGGCGATCACGGCCCCGGGCGACGTAATCCTCGCGCCTAATCCGGCCTATCCGATCCATCAGTTCGGAT
TCATACTGGCTGGTGCGACCATTCGTGCGGTTCCGACCACGCCCGACGAAAGATACTGGAAGTCGCTGGAAAGCGCGATG
GCCTACACCGTGCCGCGCCCCAGCGTACTGGTGGTCAATTATCCGTCGAACCCGACGGCGGAAGTGGTCGACCTCGCCTT
CTACGAACGACTGGTTGCATGGGCGAAGGAGAACGAGGTCTGGGTGCTGTCCGACCTCGCCTATTCCGAGCTGTGGTACA
ACGACAAGCCGACGCCTTCGATCATGCAAGTGCCGGGTGCGAAGGATGTCGCGGTCGAATTCACGACGCTTTCCAAAACC
TATTCCATGGCCGGATGGCGGATGGGCTTCGCGGTCGGCAACAAGCAGCTTATCGGGGCGATGACCCGGGTGAAGAGCTA
TGTCGACTACGGCGCCTTCACGCCGATCCAGGCCGCTGCCTGCGCTGCGCTCAACGGCCCGCAGGACGTGGTCGAGGAAA
ACCGCCTGATCTATCACAGGCGTCGCGACGTCATGGTCGAAGCCTTCGGGCGGGCGGGATGGGATATTCCGCCGCCGCCG
GCTTCGATGTTTGCATGGGCGCCGATCCCGCCGGCGCTGGCAAACCTCGGCAGCCTCGAGTTTTCCAAGCAATTGCTGAC
CGAAGCCAAAGTCGCTGTCGCCCCCGGTGTCGGCTATGGCGAAGAGGGTGAAGGATTCGTGCGAATTGCCATGGTGGAGA
ATGAGCAAAGGCTGCGTCAGGCGGCGCGCAACATTAAGCGCTATCTCGCCGACAAGGGCATCAACACCCAAGCGGCATGA

Upstream 100 bases:

>100_bases
GATGCGCGCATTATGCATTCGATTGCGCGTGCTAGAGCTTTGCGCCAGTAAGGAATTCCTGCAGGATGCAGGTCTGAAGG
AAAGCTATAGTCGGGACGAT

Downstream 100 bases:

>100_bases
CCTGATTCGCGGCCGGTCCGATTCGGGACCTGTCGGCTTTCGGCGCGTTTGCTGAATCGGGCAATTTGTCCTAAGTATGC
GCGGTAACAGGAGCCCATGA

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MDTEFYRMKRLPPYVIAEVNAMRHAARQAGEDIIDLGMGNPDRPPPQHVIDKLCEVAQKPDAHGYSQSRGIPGLRRAQAN
YYGNRFGVDIDPESEVVVTLGSKEGLASLATAITAPGDVILAPNPAYPIHQFGFILAGATIRAVPTTPDERYWKSLESAM
AYTVPRPSVLVVNYPSNPTAEVVDLAFYERLVAWAKENEVWVLSDLAYSELWYNDKPTPSIMQVPGAKDVAVEFTTLSKT
YSMAGWRMGFAVGNKQLIGAMTRVKSYVDYGAFTPIQAAACAALNGPQDVVEENRLIYHRRRDVMVEAFGRAGWDIPPPP
ASMFAWAPIPPALANLGSLEFSKQLLTEAKVAVAPGVGYGEEGEGFVRIAMVENEQRLRQAARNIKRYLADKGINTQAA

Sequences:

>Translated_399_residues
MDTEFYRMKRLPPYVIAEVNAMRHAARQAGEDIIDLGMGNPDRPPPQHVIDKLCEVAQKPDAHGYSQSRGIPGLRRAQAN
YYGNRFGVDIDPESEVVVTLGSKEGLASLATAITAPGDVILAPNPAYPIHQFGFILAGATIRAVPTTPDERYWKSLESAM
AYTVPRPSVLVVNYPSNPTAEVVDLAFYERLVAWAKENEVWVLSDLAYSELWYNDKPTPSIMQVPGAKDVAVEFTTLSKT
YSMAGWRMGFAVGNKQLIGAMTRVKSYVDYGAFTPIQAAACAALNGPQDVVEENRLIYHRRRDVMVEAFGRAGWDIPPPP
ASMFAWAPIPPALANLGSLEFSKQLLTEAKVAVAPGVGYGEEGEGFVRIAMVENEQRLRQAARNIKRYLADKGINTQAA
>Mature_399_residues
MDTEFYRMKRLPPYVIAEVNAMRHAARQAGEDIIDLGMGNPDRPPPQHVIDKLCEVAQKPDAHGYSQSRGIPGLRRAQAN
YYGNRFGVDIDPESEVVVTLGSKEGLASLATAITAPGDVILAPNPAYPIHQFGFILAGATIRAVPTTPDERYWKSLESAM
AYTVPRPSVLVVNYPSNPTAEVVDLAFYERLVAWAKENEVWVLSDLAYSELWYNDKPTPSIMQVPGAKDVAVEFTTLSKT
YSMAGWRMGFAVGNKQLIGAMTRVKSYVDYGAFTPIQAAACAALNGPQDVVEENRLIYHRRRDVMVEAFGRAGWDIPPPP
ASMFAWAPIPPALANLGSLEFSKQLLTEAKVAVAPGVGYGEEGEGFVRIAMVENEQRLRQAARNIKRYLADKGINTQAA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=394, Percent_Identity=23.3502538071066, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI56713254, Length=394, Percent_Identity=23.3502538071066, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI95147551, Length=392, Percent_Identity=21.9387755102041, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI169881279, Length=392, Percent_Identity=21.9387755102041, Blast_Score=102, Evalue=8e-22,
Organism=Escherichia coli, GI1788722, Length=393, Percent_Identity=53.4351145038168, Blast_Score=444, Evalue=1e-126,
Organism=Escherichia coli, GI1786816, Length=359, Percent_Identity=25.0696378830084, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1788627, Length=289, Percent_Identity=28.0276816608997, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788332, Length=211, Percent_Identity=27.4881516587678, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71994476, Length=391, Percent_Identity=24.8081841432225, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI71994472, Length=391, Percent_Identity=24.8081841432225, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=394, Percent_Identity=21.3197969543147, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17567663, Length=383, Percent_Identity=21.4099216710183, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=387, Percent_Identity=22.2222222222222, Blast_Score=99, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6320317, Length=349, Percent_Identity=23.4957020057307, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573069, Length=393, Percent_Identity=23.6641221374046, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24646114, Length=393, Percent_Identity=23.6641221374046, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI28573067, Length=393, Percent_Identity=23.6641221374046, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI28573065, Length=393, Percent_Identity=23.6641221374046, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI45551451, Length=401, Percent_Identity=23.4413965087282, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641770, Length=401, Percent_Identity=23.4413965087282, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641760, Length=401, Percent_Identity=23.4413965087282, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641768, Length=401, Percent_Identity=23.4413965087282, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641766, Length=401, Percent_Identity=23.4413965087282, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641764, Length=401, Percent_Identity=23.4413965087282, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 43786; Mature: 43786

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTEFYRMKRLPPYVIAEVNAMRHAARQAGEDIIDLGMGNPDRPPPQHVIDKLCEVAQKP
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHCCC
DAHGYSQSRGIPGLRRAQANYYGNRFGVDIDPESEVVVTLGSKEGLASLATAITAPGDVI
CCCCCCHHCCCCHHHHHHHHHCCCEECCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCEE
LAPNPAYPIHQFGFILAGATIRAVPTTPDERYWKSLESAMAYTVPRPSVLVVNYPSNPTA
ECCCCCCCHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHEECCCCCEEEEECCCCCHH
EVVDLAFYERLVAWAKENEVWVLSDLAYSELWYNDKPTPSIMQVPGAKDVAVEFTTLSKT
HHHHHHHHHHHHHHHCCCCEEEEECCHHHHHCCCCCCCCCEEECCCCCCEEEEEEEHHHH
YSMAGWRMGFAVGNKQLIGAMTRVKSYVDYGAFTPIQAAACAALNGPQDVVEENRLIYHR
HHHCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHCCCEEEHH
RRDVMVEAFGRAGWDIPPPPASMFAWAPIPPALANLGSLEFSKQLLTEAKVAVAPGVGYG
HHHHHHHHHCCCCCCCCCCCCCCEEECCCCHHHHHCCCHHHHHHHHHHHHHEECCCCCCC
EEGEGFVRIAMVENEQRLRQAARNIKRYLADKGINTQAA
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDTEFYRMKRLPPYVIAEVNAMRHAARQAGEDIIDLGMGNPDRPPPQHVIDKLCEVAQKP
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHCCC
DAHGYSQSRGIPGLRRAQANYYGNRFGVDIDPESEVVVTLGSKEGLASLATAITAPGDVI
CCCCCCHHCCCCHHHHHHHHHCCCEECCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCEE
LAPNPAYPIHQFGFILAGATIRAVPTTPDERYWKSLESAMAYTVPRPSVLVVNYPSNPTA
ECCCCCCCHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHEECCCCCEEEEECCCCCHH
EVVDLAFYERLVAWAKENEVWVLSDLAYSELWYNDKPTPSIMQVPGAKDVAVEFTTLSKT
HHHHHHHHHHHHHHHCCCCEEEEECCHHHHHCCCCCCCCCEEECCCCCCEEEEEEEHHHH
YSMAGWRMGFAVGNKQLIGAMTRVKSYVDYGAFTPIQAAACAALNGPQDVVEENRLIYHR
HHHCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHCCCEEEHH
RRDVMVEAFGRAGWDIPPPPASMFAWAPIPPALANLGSLEFSKQLLTEAKVAVAPGVGYG
HHHHHHHHHCCCCCCCCCCCCCCEEECCCCHHHHHCCCHHHHHHHHHHHHHEECCCCCCC
EEGEGFVRIAMVENEQRLRQAARNIKRYLADKGINTQAA
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430; 9734305 [H]