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The map label for this gene is yngJ [H]

Identifier: 85374751

GI number: 85374751

Start: 1960312

End: 1961664

Strand: Direct

Name: yngJ [H]

Synonym: ELI_09620

Alternate gene names: 85374751

Gene position: 1960312-1961664 (Clockwise)

Preceding gene: 85374750

Following gene: 85374752

Centisome position: 64.22

GC content: 62.75

Gene sequence:

>1353_bases
ATGAATTTCGAACCGACAGAACGGCAGCAATATTGGCGCGACCGGGTCAAGACCTTCATCGAGAATGAAATCCGCCCCGC
GGTCCCGACCTACAAGGAACAGGACGCCGAAGGCGATCGCTGGAAAGTGATCCAGGTGGTCGAAGACCTCAAGGCGAAGG
CCAAGGATCAGGGCATCTGGAACCTGTTCATGCCGCCGCGCAACGAAGGCCATCACCATGTCGAGGAGAGCTTCGAGTTC
GAAGGGCCGGGCCTGACCAATCTCGAATATGCGCTCTGCGCCGAGGAAATGGGCCGCGTCGGCTTCGCTTCGGAAGCTTT
CAACTGCTCGGCGCCCGATACCGGCAATATGGAGGTCTTCCACCGCTACGGTACGCTGGAACAGAAGGAGCAGTGGCTGC
GTCCGCTGATGAACGGCGAAATCCGCTCCGCCTTCCTGATGACCGAGCCGTACACCGCTTCCTCCGACGCGACGAATATC
GAGACGCGGATGGAGCGCGATGGCGACCATTACGTCATCAACGGTCGCAAGTGGTGGTCTTCGGGTCTGGGCGATCCGCG
CTGCAAGGTGGCGATCGTGATGGGCAAGACCAATGTCGAGGCGCAGCGCCACGCGCAGCAATCGCAGGTTATCGTCCCCA
TCGACTCTCCCGGTGTGAACATCATCCGCCACCTTCCGGTGTTCGGCTACGACGATGCCCCGCACGGCCACATGGAAGTC
GAGCTGAAAGACGTTCGCGTACCGGTTGAGAACGTCATCCTTGGCGAAGGCCGCGGCTTCGAAATCGCACAGGGCCGCCT
GGGCCCGGGCCGCATCCATCACTGCATGCGCACCATCGGCGTGGCCGAGGAAGCGCTGGAGAAGATGTGCAAGCGGCTGC
AGGAGCGCGAGGCGTTCGGCAAGCCGATCTACAAGCATTCGGTCTGGGAAGAGCGCATCGCCCGCGCCCGGATCGACATC
GACATGACTCGCCTGCTCTGTCTCAAGGCTGCCGACATGATGGACAAGGTCGGCAACAAGTCGGCCAAGCAGGAAATCGC
CATGATCAAGGTGCAGGCGCCCAACATGGCGCTGCGGATCATCGACGATGCGATTCAGGCCCATGGCGGCGGCGGTGTGA
GCGAGGATTACGGTCTTGCCAGCGCCTATGCCCACCAGCGCACGCTGCGGCTGGCCGACGGTCCGGACGAAGTTCACGCC
CGCTCGATCGCGCGCATGGAGATCGGCAAGCACCAGCCCAACGAAGGCCCGACTGCCAATGCTTTGCGCGGCAGCAACGC
GCACTACGCCAGCGCCGGAAGCGCAGCTGCCAGCGCGGGCATGAGCTCGGGAGACGTAGGCGTTTCGCGCTAG

Upstream 100 bases:

>100_bases
CCTAGGAGCTCGCTTGGAGAATCACCCTTGGCGCAAGCAGGGCGCTCTGCCACGGTTGCGCCAACAGAATCGCAGAACAC
GATAGAGAGAGGATACCCCC

Downstream 100 bases:

>100_bases
AAACAGTGCACCAGACATAGCCGTTCGTGCTGAGCCTGTCGAAGCACTGCTCTTCTCTGTGAGCGCGGCGCCAGAATTAA
GGACGGCCCTTGGACAAGCT

Product: acyl-CoA dehydrogenase family protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MNFEPTERQQYWRDRVKTFIENEIRPAVPTYKEQDAEGDRWKVIQVVEDLKAKAKDQGIWNLFMPPRNEGHHHVEESFEF
EGPGLTNLEYALCAEEMGRVGFASEAFNCSAPDTGNMEVFHRYGTLEQKEQWLRPLMNGEIRSAFLMTEPYTASSDATNI
ETRMERDGDHYVINGRKWWSSGLGDPRCKVAIVMGKTNVEAQRHAQQSQVIVPIDSPGVNIIRHLPVFGYDDAPHGHMEV
ELKDVRVPVENVILGEGRGFEIAQGRLGPGRIHHCMRTIGVAEEALEKMCKRLQEREAFGKPIYKHSVWEERIARARIDI
DMTRLLCLKAADMMDKVGNKSAKQEIAMIKVQAPNMALRIIDDAIQAHGGGGVSEDYGLASAYAHQRTLRLADGPDEVHA
RSIARMEIGKHQPNEGPTANALRGSNAHYASAGSAAASAGMSSGDVGVSR

Sequences:

>Translated_450_residues
MNFEPTERQQYWRDRVKTFIENEIRPAVPTYKEQDAEGDRWKVIQVVEDLKAKAKDQGIWNLFMPPRNEGHHHVEESFEF
EGPGLTNLEYALCAEEMGRVGFASEAFNCSAPDTGNMEVFHRYGTLEQKEQWLRPLMNGEIRSAFLMTEPYTASSDATNI
ETRMERDGDHYVINGRKWWSSGLGDPRCKVAIVMGKTNVEAQRHAQQSQVIVPIDSPGVNIIRHLPVFGYDDAPHGHMEV
ELKDVRVPVENVILGEGRGFEIAQGRLGPGRIHHCMRTIGVAEEALEKMCKRLQEREAFGKPIYKHSVWEERIARARIDI
DMTRLLCLKAADMMDKVGNKSAKQEIAMIKVQAPNMALRIIDDAIQAHGGGGVSEDYGLASAYAHQRTLRLADGPDEVHA
RSIARMEIGKHQPNEGPTANALRGSNAHYASAGSAAASAGMSSGDVGVSR
>Mature_450_residues
MNFEPTERQQYWRDRVKTFIENEIRPAVPTYKEQDAEGDRWKVIQVVEDLKAKAKDQGIWNLFMPPRNEGHHHVEESFEF
EGPGLTNLEYALCAEEMGRVGFASEAFNCSAPDTGNMEVFHRYGTLEQKEQWLRPLMNGEIRSAFLMTEPYTASSDATNI
ETRMERDGDHYVINGRKWWSSGLGDPRCKVAIVMGKTNVEAQRHAQQSQVIVPIDSPGVNIIRHLPVFGYDDAPHGHMEV
ELKDVRVPVENVILGEGRGFEIAQGRLGPGRIHHCMRTIGVAEEALEKMCKRLQEREAFGKPIYKHSVWEERIARARIDI
DMTRLLCLKAADMMDKVGNKSAKQEIAMIKVQAPNMALRIIDDAIQAHGGGGVSEDYGLASAYAHQRTLRLADGPDEVHA
RSIARMEIGKHQPNEGPTANALRGSNAHYASAGSAAASAGMSSGDVGVSR

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI38505218, Length=412, Percent_Identity=54.126213592233, Blast_Score=443, Evalue=1e-124,
Organism=Homo sapiens, GI211971008, Length=411, Percent_Identity=52.3114355231144, Blast_Score=430, Evalue=1e-120,
Organism=Homo sapiens, GI48976061, Length=411, Percent_Identity=52.3114355231144, Blast_Score=429, Evalue=1e-120,
Organism=Homo sapiens, GI4557233, Length=326, Percent_Identity=29.4478527607362, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI187960098, Length=419, Percent_Identity=26.491646778043, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI4557231, Length=419, Percent_Identity=26.491646778043, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI4501859, Length=409, Percent_Identity=25.4278728606357, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI7656849, Length=326, Percent_Identity=27.3006134969325, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI226958412, Length=403, Percent_Identity=25.0620347394541, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI226958414, Length=341, Percent_Identity=26.6862170087977, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI21361497, Length=397, Percent_Identity=27.9596977329975, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI76496475, Length=333, Percent_Identity=27.9279279279279, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4557235, Length=333, Percent_Identity=27.9279279279279, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4501857, Length=306, Percent_Identity=27.1241830065359, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI4503943, Length=385, Percent_Identity=23.1168831168831, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI7669494, Length=353, Percent_Identity=23.7960339943343, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI87081958, Length=320, Percent_Identity=27.5, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786223, Length=412, Percent_Identity=21.8446601941748, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562446, Length=404, Percent_Identity=49.5049504950495, Blast_Score=384, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17534899, Length=411, Percent_Identity=26.5206812652068, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17569725, Length=421, Percent_Identity=24.9406175771971, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71985184, Length=391, Percent_Identity=27.8772378516624, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17551932, Length=343, Percent_Identity=25.0728862973761, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17506239, Length=403, Percent_Identity=25.8064516129032, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17505929, Length=385, Percent_Identity=24.1558441558442, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17570075, Length=425, Percent_Identity=24.2352941176471, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17508101, Length=329, Percent_Identity=25.531914893617, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17533517, Length=324, Percent_Identity=25.6172839506173, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17538396, Length=403, Percent_Identity=22.8287841191067, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71990804, Length=256, Percent_Identity=29.6875, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71985192, Length=300, Percent_Identity=27.6666666666667, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI71982178, Length=300, Percent_Identity=25.3333333333333, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17534353, Length=330, Percent_Identity=23.9393939393939, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32563615, Length=240, Percent_Identity=28.3333333333333, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24660351, Length=414, Percent_Identity=28.743961352657, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI21356377, Length=326, Percent_Identity=30.6748466257669, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281363737, Length=342, Percent_Identity=28.9473684210526, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24666513, Length=336, Percent_Identity=27.3809523809524, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24646207, Length=335, Percent_Identity=28.955223880597, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI21355753, Length=296, Percent_Identity=26.6891891891892, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19920834, Length=328, Percent_Identity=23.780487804878, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 50211; Mature: 50211

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFEPTERQQYWRDRVKTFIENEIRPAVPTYKEQDAEGDRWKVIQVVEDLKAKAKDQGIW
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCE
NLFMPPRNEGHHHVEESFEFEGPGLTNLEYALCAEEMGRVGFASEAFNCSAPDTGNMEVF
EEECCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHH
HRYGTLEQKEQWLRPLMNGEIRSAFLMTEPYTASSDATNIETRMERDGDHYVINGRKWWS
HHHCCHHHHHHHHHHHHCCCHHEEEEEECCCCCCCCCCCHHHHHHCCCCEEEECCCHHHC
SGLGDPRCKVAIVMGKTNVEAQRHAQQSQVIVPIDSPGVNIIRHLPVFGYDDAPHGHMEV
CCCCCCCEEEEEEECCCCCHHHHHHCCCCEEEEECCCCHHHHHHCCCCCCCCCCCCEEEE
ELKDVRVPVENVILGEGRGFEIAQGRLGPGRIHHCMRTIGVAEEALEKMCKRLQEREAFG
EEEEEECCHHHEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KPIYKHSVWEERIARARIDIDMTRLLCLKAADMMDKVGNKSAKQEIAMIKVQAPNMALRI
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHCEEEEEEEECCCEEEHH
IDDAIQAHGGGGVSEDYGLASAYAHQRTLRLADGPDEVHARSIARMEIGKHQPNEGPTAN
HHHHHHHCCCCCCCCCCCHHHHHHHHHEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCC
ALRGSNAHYASAGSAAASAGMSSGDVGVSR
CCCCCCCCCCCCCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNFEPTERQQYWRDRVKTFIENEIRPAVPTYKEQDAEGDRWKVIQVVEDLKAKAKDQGIW
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCE
NLFMPPRNEGHHHVEESFEFEGPGLTNLEYALCAEEMGRVGFASEAFNCSAPDTGNMEVF
EEECCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHH
HRYGTLEQKEQWLRPLMNGEIRSAFLMTEPYTASSDATNIETRMERDGDHYVINGRKWWS
HHHCCHHHHHHHHHHHHCCCHHEEEEEECCCCCCCCCCCHHHHHHCCCCEEEECCCHHHC
SGLGDPRCKVAIVMGKTNVEAQRHAQQSQVIVPIDSPGVNIIRHLPVFGYDDAPHGHMEV
CCCCCCCEEEEEEECCCCCHHHHHHCCCCEEEEECCCCHHHHHHCCCCCCCCCCCCEEEE
ELKDVRVPVENVILGEGRGFEIAQGRLGPGRIHHCMRTIGVAEEALEKMCKRLQEREAFG
EEEEEECCHHHEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KPIYKHSVWEERIARARIDIDMTRLLCLKAADMMDKVGNKSAKQEIAMIKVQAPNMALRI
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHCEEEEEEEECCCEEEHH
IDDAIQAHGGGGVSEDYGLASAYAHQRTLRLADGPDEVHARSIARMEIGKHQPNEGPTAN
HHHHHHHCCCCCCCCCCCHHHHHHHHHEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCC
ALRGSNAHYASAGSAAASAGMSSGDVGVSR
CCCCCCCCCCCCCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]