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The map label for this gene is acr1 [H]

Identifier: 85374724

GI number: 85374724

Start: 1940752

End: 1941546

Strand: Direct

Name: acr1 [H]

Synonym: ELI_09485

Alternate gene names: 85374724

Gene position: 1940752-1941546 (Clockwise)

Preceding gene: 85374723

Following gene: 85374726

Centisome position: 63.58

GC content: 65.66

Gene sequence:

>795_bases
ATGACCAAGCCCGTGTTTCTCGTGATCGGTGCCGGAGCGGGCATCGGCGGCCATGCAGCGAAGCGCTTCGCCAAAGGCGG
CTATCACGCGGTGTTGGCGCGCCGGTCCGACGAGGAAGGCCTCGGGCGGCTGGTCCGGCAGATCGAAGAGGCAGGCGGCA
GCGCGAGTGGCATGCTGCTCGACGTAAGCGACGACGGCACGATCGAAGACCTGGTCGAGCGCATCGAGACCGATGTCGGA
CCCATCGACACCGCGCTCTACAATCTCGGCGCGCAAATCGGGAATCGCCCCCTGAGCGATACGCCGCACCGCACCTTCGA
ACTCGGCTGGCGTCTCGGCTGCTTCGGCCTGTTCCGTCTCGCCCATGCTGTATTGCCGCATATGGTCGAGCGCGGAAAAG
GGACCTTATTGGTCACCAGCGCCACCGCAGCCGTGCGCGGCAATGCGGGGCAGCACAGCCATGCCGCCGCGATGGGCGGT
CGCCGCATGCTGTGCCAGACCCTCAACGCCGAATTCGCTCCGCAGGGCGTGCATGTCGCGCATGTCGTGGTCGACGGCTC
GGTCGATGCGCCCGACACGCTGGGCAAACTTCTCGGCGACAAGTTCGAAGCCTACAAGGCGCACAAGGGCGAGGACGGGG
TGATCGACCCGGCGAACCTCGCGGATACCTATTGGCACCTCGCCCAGCAGCCGCGCAATTGCTGGACCCACGAACTCGAC
GTGCGACCGTTTACCGACGTGCCATGGTGGAACGACAACCCGCCGGCGGCGATCGATACGAAGGCGAAGAAATAG

Upstream 100 bases:

>100_bases
ATGGGCGTCGCTCTCGCGACGGGCGGCGATACCGATTATGCGCGCACCGCTGCGGTCGCTGCGGCTAACAAGCTGCACAT
TCACTACGGAGACTAGCGTC

Downstream 100 bases:

>100_bases
GGGCGGCTACCCCTTCCACTCGCGTCGTTCTTCGGCCGCCTTGAGCACTTCGTACGACAGTTGCAGCTTCTGAAATTCCT
CCGCCGCTTCCTTGTCGCCC

Product: oxidoreductase, short chain dehydrogenase/reductase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MTKPVFLVIGAGAGIGGHAAKRFAKGGYHAVLARRSDEEGLGRLVRQIEEAGGSASGMLLDVSDDGTIEDLVERIETDVG
PIDTALYNLGAQIGNRPLSDTPHRTFELGWRLGCFGLFRLAHAVLPHMVERGKGTLLVTSATAAVRGNAGQHSHAAAMGG
RRMLCQTLNAEFAPQGVHVAHVVVDGSVDAPDTLGKLLGDKFEAYKAHKGEDGVIDPANLADTYWHLAQQPRNCWTHELD
VRPFTDVPWWNDNPPAAIDTKAKK

Sequences:

>Translated_264_residues
MTKPVFLVIGAGAGIGGHAAKRFAKGGYHAVLARRSDEEGLGRLVRQIEEAGGSASGMLLDVSDDGTIEDLVERIETDVG
PIDTALYNLGAQIGNRPLSDTPHRTFELGWRLGCFGLFRLAHAVLPHMVERGKGTLLVTSATAAVRGNAGQHSHAAAMGG
RRMLCQTLNAEFAPQGVHVAHVVVDGSVDAPDTLGKLLGDKFEAYKAHKGEDGVIDPANLADTYWHLAQQPRNCWTHELD
VRPFTDVPWWNDNPPAAIDTKAKK
>Mature_263_residues
TKPVFLVIGAGAGIGGHAAKRFAKGGYHAVLARRSDEEGLGRLVRQIEEAGGSASGMLLDVSDDGTIEDLVERIETDVGP
IDTALYNLGAQIGNRPLSDTPHRTFELGWRLGCFGLFRLAHAVLPHMVERGKGTLLVTSATAAVRGNAGQHSHAAAMGGR
RMLCQTLNAEFAPQGVHVAHVVVDGSVDAPDTLGKLLGDKFEAYKAHKGEDGVIDPANLADTYWHLAQQPRNCWTHELDV
RPFTDVPWWNDNPPAAIDTKAKK

Specific function: Catalyzes the NADPH-dependent reduction of long chain acyl-CoA to the corresponding aldehyde [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Escherichia coli, GI1787820, Length=252, Percent_Identity=24.6031746031746, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787905, Length=142, Percent_Identity=28.8732394366197, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=190, Percent_Identity=26.8421052631579, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=154, Percent_Identity=30.5194805194805, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28323; Mature: 28192

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPVFLVIGAGAGIGGHAAKRFAKGGYHAVLARRSDEEGLGRLVRQIEEAGGSASGMLL
CCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCEEE
DVSDDGTIEDLVERIETDVGPIDTALYNLGAQIGNRPLSDTPHRTFELGWRLGCFGLFRL
EECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
AHAVLPHMVERGKGTLLVTSATAAVRGNAGQHSHAAAMGGRRMLCQTLNAEFAPQGVHVA
HHHHHHHHHHCCCCCEEEEECCHHHCCCCCCCHHHHHHCCHHHHHHHHCCCCCCCCCEEE
HVVVDGSVDAPDTLGKLLGDKFEAYKAHKGEDGVIDPANLADTYWHLAQQPRNCWTHELD
EEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHCCCEECC
VRPFTDVPWWNDNPPAAIDTKAKK
CCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TKPVFLVIGAGAGIGGHAAKRFAKGGYHAVLARRSDEEGLGRLVRQIEEAGGSASGMLL
CCCEEEEEECCCCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCEEE
DVSDDGTIEDLVERIETDVGPIDTALYNLGAQIGNRPLSDTPHRTFELGWRLGCFGLFRL
EECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
AHAVLPHMVERGKGTLLVTSATAAVRGNAGQHSHAAAMGGRRMLCQTLNAEFAPQGVHVA
HHHHHHHHHHCCCCCEEEEECCHHHCCCCCCCHHHHHHCCHHHHHHHHCCCCCCCCCEEE
HVVVDGSVDAPDTLGKLLGDKFEAYKAHKGEDGVIDPANLADTYWHLAQQPRNCWTHELD
EEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHCCCEECC
VRPFTDVPWWNDNPPAAIDTKAKK
CCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA