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The map label for this gene is infC

Identifier: 85374713

GI number: 85374713

Start: 1929804

End: 1930322

Strand: Direct

Name: infC

Synonym: ELI_09430

Alternate gene names: 85374713

Gene position: 1929804-1930322 (Clockwise)

Preceding gene: 85374712

Following gene: 85374715

Centisome position: 63.22

GC content: 56.45

Gene sequence:

>519_bases
ATGCAGCCGCCGGTCAAGAGCGGTCCGCGATACGACAATTTCATCCAGTCGCCCAAGGTCCGTGTCATCGATGATGAAGG
CGAAAACCTTGGTGTAATGTTCACAAAAGAAGCCATGGAACAGGCCCAGGAAAAGGGGCTGAATTTGGTTGAGGTCTCGC
CGAACGCAGATCCGCCCGTGGCGAAGTTCCTCGATGTCGGAAAATATCGCTACGAGGCGCAGAAGAAAGCGAACCTCGCG
CGCAAGACGCAGAAGACCCAGGACATCAAAGAGGTCAAAATGCGTCCCAACATCGACACGCACGATTACGACGTGAAGAT
GCGCAACGTGAACAAGTTCATCGAGAACGGCGACAAGGTGAAGGTGACGCTGCGTTTCCGGGGCCGCGAAATGGCACACC
AGAACCTCGGCATGGACCTGCTCAACCGGGTCCGCGACGATGTCGAGGAGATCGCCAAGGTAGAAGCTTTCCCGCGTCTC
GAAGGTCGGCAGATGCTGATGGTGCTGGCGCCCAAGTAA

Upstream 100 bases:

>100_bases
CGCTTCCCCTTTGCGAATCCCTCGCGCGCGCCCTACATAGCGCGCAGTTCACTCGGCAATTTCAGGAGAAAGCCCCATAG
CCCGTCCACCACGTCGTTCC

Downstream 100 bases:

>100_bases
GGCGTCGGCAACCAAGCTCTTCGCTCTATTCTATCTCGAACCTTTCGACCGTGAACCGCGCGGGGCCGGTGGCATAGACC
CCGTGGCCCCGCAGCGTGTT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MQPPVKSGPRYDNFIQSPKVRVIDDEGENLGVMFTKEAMEQAQEKGLNLVEVSPNADPPVAKFLDVGKYRYEAQKKANLA
RKTQKTQDIKEVKMRPNIDTHDYDVKMRNVNKFIENGDKVKVTLRFRGREMAHQNLGMDLLNRVRDDVEEIAKVEAFPRL
EGRQMLMVLAPK

Sequences:

>Translated_172_residues
MQPPVKSGPRYDNFIQSPKVRVIDDEGENLGVMFTKEAMEQAQEKGLNLVEVSPNADPPVAKFLDVGKYRYEAQKKANLA
RKTQKTQDIKEVKMRPNIDTHDYDVKMRNVNKFIENGDKVKVTLRFRGREMAHQNLGMDLLNRVRDDVEEIAKVEAFPRL
EGRQMLMVLAPK
>Mature_172_residues
MQPPVKSGPRYDNFIQSPKVRVIDDEGENLGVMFTKEAMEQAQEKGLNLVEVSPNADPPVAKFLDVGKYRYEAQKKANLA
RKTQKTQDIKEVKMRPNIDTHDYDVKMRNVNKFIENGDKVKVTLRFRGREMAHQNLGMDLLNRVRDDVEEIAKVEAFPRL
EGRQMLMVLAPK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=53.6585365853659, Blast_Score=180, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 19814; Mature: 19814

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPPVKSGPRYDNFIQSPKVRVIDDEGENLGVMFTKEAMEQAQEKGLNLVEVSPNADPPV
CCCCCCCCCCCCHHHCCCCEEEECCCCCCEEEEEEHHHHHHHHHCCCEEEEECCCCCCHH
AKFLDVGKYRYEAQKKANLARKTQKTQDIKEVKMRPNIDTHDYDVKMRNVNKFIENGDKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHCCCEE
KVTLRFRGREMAHQNLGMDLLNRVRDDVEEIAKVEAFPRLEGRQMLMVLAPK
EEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
>Mature Secondary Structure
MQPPVKSGPRYDNFIQSPKVRVIDDEGENLGVMFTKEAMEQAQEKGLNLVEVSPNADPPV
CCCCCCCCCCCCHHHCCCCEEEECCCCCCEEEEEEHHHHHHHHHCCCEEEEECCCCCCHH
AKFLDVGKYRYEAQKKANLARKTQKTQDIKEVKMRPNIDTHDYDVKMRNVNKFIENGDKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHCCCEE
KVTLRFRGREMAHQNLGMDLLNRVRDDVEEIAKVEAFPRLEGRQMLMVLAPK
EEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA