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The map label for this gene is gpsA

Identifier: 85374660

GI number: 85374660

Start: 1864016

End: 1865008

Strand: Direct

Name: gpsA

Synonym: ELI_09165

Alternate gene names: 85374660

Gene position: 1864016-1865008 (Clockwise)

Preceding gene: 85374659

Following gene: 85374661

Centisome position: 61.07

GC content: 65.96

Gene sequence:

>993_bases
GTGACGGCAGAAATCGCAGTCCTCGGCGGCGGCGCATGGGGCACCGCGCTTGCGCAGATGCTCGCCAGCGACGGGCAAGA
TGTCTTGCTGTGGGCTCGAGAAAGCGAGGTCGTGGCCGAGGTCAACGCCGATCATCTCAACAGCATTTATCTGCCCGGTG
CCCGGCTGGCCGAAAACATTAAGGCTACAGGCGAGGTCTCCGATCTCTCCGCCATTCCCACTCTACTCGTGGTCACGCCC
GCGCAGCATATGGGCGCAGTGTTGAAAACGCTCCCTGAAAATCCGCGCGACCTCGTACTGTGCAGCAAGGGGATTGAGCA
GGACACCGGGCGGCTCATGAACGATGTGGCCGCCGAAGCCTGCCCCGACAGCGAGATCGCAATCCTTTCCGGTCCGACCT
TCGCGCATGAGGTCGCGGCAGGCCTGCCGACCGCCGTAACGCTGGCTTGCAGCAGCCGTGAGCAATGGGAACGGCTGAAG
CCGCTTATCGCGCGGCCTGCTTTCCGTCCCTATTACAGCGACGATGTAAGCGGCGCGGAGATCGGCGGCGCGGTGAAGAA
CGTGCTCGCCATTGCCTGCGGCGTGGTCGACGGGCTCGGGCTCGGCCAGAATGCCCGCGCGGCGCTGATCGCGCGCGGCT
ATGCCGAAATGCTGCGCTTCGGCGAGGCTCTGGGAGCGCAGGCGGAGACGCTTGCGGGCCTGTGCGGGCTAGGCGATCTC
GTCCTGACCTGTTCCTCCACCTCCAGCCGCAACTTCTCGCTCGGCAAGGCATTGGGCGAAGGGCGAACAGCGGCAGACCT
GATGGCCGACCGGACAACGGTGGCGGAAGGTGCCTACACCGCGCCCGTGCTGGCCGAACTGGCCGAAGCGAAGGGCGTGG
ATATGCCGATCGTCCAGGCGGTCAATCGCATTATCGCCGGTGCAGACGCGCAGGCCGTGGTCGCACAGCTGCTCGCTCGC
CCGCTGCGCGCCGAGCACGAGTCCGACGCTTGA

Upstream 100 bases:

>100_bases
GGCTAGACTTGGAACAGGACGATCCGCTCGATTTCCGCGCGCGGCCGCGCTGGCCGCTCGATCCGGAAGCGGAGCCGGTA
CGCGGGGCGGGAGTGAAGGC

Downstream 100 bases:

>100_bases
GCATTACTCCGCCGCCCGGCCCGCCCACCAAACCGCCTGCCCCGGACGACAGCGCGGGCGACATGGCTGCGCTCGCCAAG
GGCGGGCGGACCAATTTCTT

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTAEIAVLGGGAWGTALAQMLASDGQDVLLWARESEVVAEVNADHLNSIYLPGARLAENIKATGEVSDLSAIPTLLVVTP
AQHMGAVLKTLPENPRDLVLCSKGIEQDTGRLMNDVAAEACPDSEIAILSGPTFAHEVAAGLPTAVTLACSSREQWERLK
PLIARPAFRPYYSDDVSGAEIGGAVKNVLAIACGVVDGLGLGQNARAALIARGYAEMLRFGEALGAQAETLAGLCGLGDL
VLTCSSTSSRNFSLGKALGEGRTAADLMADRTTVAEGAYTAPVLAELAEAKGVDMPIVQAVNRIIAGADAQAVVAQLLAR
PLRAEHESDA

Sequences:

>Translated_330_residues
MTAEIAVLGGGAWGTALAQMLASDGQDVLLWARESEVVAEVNADHLNSIYLPGARLAENIKATGEVSDLSAIPTLLVVTP
AQHMGAVLKTLPENPRDLVLCSKGIEQDTGRLMNDVAAEACPDSEIAILSGPTFAHEVAAGLPTAVTLACSSREQWERLK
PLIARPAFRPYYSDDVSGAEIGGAVKNVLAIACGVVDGLGLGQNARAALIARGYAEMLRFGEALGAQAETLAGLCGLGDL
VLTCSSTSSRNFSLGKALGEGRTAADLMADRTTVAEGAYTAPVLAELAEAKGVDMPIVQAVNRIIAGADAQAVVAQLLAR
PLRAEHESDA
>Mature_329_residues
TAEIAVLGGGAWGTALAQMLASDGQDVLLWARESEVVAEVNADHLNSIYLPGARLAENIKATGEVSDLSAIPTLLVVTPA
QHMGAVLKTLPENPRDLVLCSKGIEQDTGRLMNDVAAEACPDSEIAILSGPTFAHEVAAGLPTAVTLACSSREQWERLKP
LIARPAFRPYYSDDVSGAEIGGAVKNVLAIACGVVDGLGLGQNARAALIARGYAEMLRFGEALGAQAETLAGLCGLGDLV
LTCSSTSSRNFSLGKALGEGRTAADLMADRTTVAEGAYTAPVLAELAEAKGVDMPIVQAVNRIIAGADAQAVVAQLLARP
LRAEHESDA

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI24307999, Length=328, Percent_Identity=29.2682926829268, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI33695088, Length=330, Percent_Identity=28.4848484848485, Blast_Score=113, Evalue=3e-25,
Organism=Escherichia coli, GI1790037, Length=334, Percent_Identity=41.0179640718563, Blast_Score=231, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI17507425, Length=358, Percent_Identity=27.3743016759777, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI32564399, Length=335, Percent_Identity=29.8507462686567, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI32564403, Length=344, Percent_Identity=29.0697674418605, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI193210136, Length=344, Percent_Identity=29.0697674418605, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI193210134, Length=327, Percent_Identity=26.9113149847095, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6320181, Length=342, Percent_Identity=28.9473684210526, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324513, Length=344, Percent_Identity=27.3255813953488, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI22026922, Length=329, Percent_Identity=25.531914893617, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17136202, Length=324, Percent_Identity=26.8518518518519, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17136200, Length=324, Percent_Identity=26.8518518518519, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17136204, Length=324, Percent_Identity=26.8518518518519, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45551945, Length=288, Percent_Identity=26.3888888888889, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281362270, Length=288, Percent_Identity=26.3888888888889, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24648969, Length=248, Percent_Identity=27.4193548387097, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_ERYLH (Q2N8R6)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_458722.1
- HSSP:   Q8N1B0
- ProteinModelPortal:   Q2N8R6
- SMR:   Q2N8R6
- STRING:   Q2N8R6
- GeneID:   3869610
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_09165
- NMPDR:   fig|314225.3.peg.1209
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   ALVACCK
- PhylomeDB:   Q2N8R6
- ProtClustDB:   PRK00094
- BioCyc:   ELIT314225:ELI_09165-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 34079; Mature: 33948

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 186-186 BINDING 103-103 BINDING 103-103 BINDING 135-135 BINDING 250-250 BINDING 276-276

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAEIAVLGGGAWGTALAQMLASDGQDVLLWARESEVVAEVNADHLNSIYLPGARLAENI
CCCEEEEEECCHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCHHHCCEEECCCHHHHHHH
KATGEVSDLSAIPTLLVVTPAQHMGAVLKTLPENPRDLVLCSKGIEQDTGRLMNDVAAEA
HCCCCHHHHHHHCEEEEECCHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHH
CPDSEIAILSGPTFAHEVAAGLPTAVTLACSSREQWERLKPLIARPAFRPYYSDDVSGAE
CCCCCEEEEECCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCHH
IGGAVKNVLAIACGVVDGLGLGQNARAALIARGYAEMLRFGEALGAQAETLAGLCGLGDL
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCE
VLTCSSTSSRNFSLGKALGEGRTAADLMADRTTVAEGAYTAPVLAELAEAKGVDMPIVQA
EEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHH
VNRIIAGADAQAVVAQLLARPLRAEHESDA
HHHHHCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TAEIAVLGGGAWGTALAQMLASDGQDVLLWARESEVVAEVNADHLNSIYLPGARLAENI
CCEEEEEECCHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCHHHCCEEECCCHHHHHHH
KATGEVSDLSAIPTLLVVTPAQHMGAVLKTLPENPRDLVLCSKGIEQDTGRLMNDVAAEA
HCCCCHHHHHHHCEEEEECCHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHH
CPDSEIAILSGPTFAHEVAAGLPTAVTLACSSREQWERLKPLIARPAFRPYYSDDVSGAE
CCCCCEEEEECCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCHH
IGGAVKNVLAIACGVVDGLGLGQNARAALIARGYAEMLRFGEALGAQAETLAGLCGLGDL
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCE
VLTCSSTSSRNFSLGKALGEGRTAADLMADRTTVAEGAYTAPVLAELAEAKGVDMPIVQA
EEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHH
VNRIIAGADAQAVVAQLLARPLRAEHESDA
HHHHHCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA