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The map label for this gene is pabA [H]

Identifier: 85374128

GI number: 85374128

Start: 1349500

End: 1350111

Strand: Direct

Name: pabA [H]

Synonym: ELI_06505

Alternate gene names: 85374128

Gene position: 1349500-1350111 (Clockwise)

Preceding gene: 85374127

Following gene: 85374129

Centisome position: 44.21

GC content: 62.42

Gene sequence:

>612_bases
ATGATCCTCGTCATCGACAATTACGACAGTTTCACTTTCAATCTCGTCCATTACCTGATGGAACTGGGGGCAGAGGTGCG
GGTCGAGCGCAATGACGCGCTGACAGCTGCGGACGCGATCGCCAGCGGCGCGAAGGGCATTCTCATCTCTCCCGGTCCCT
GCACGCCCGATGAAGCGGGGATCAGCCTCGATCTCGTGGGCGCCTGCGCGGATGCCGATATGCCGCTCCTCGGGGTGTGC
CTCGGGCATCAGGCAATCGGCCAGTATTTTGGCGGGCGCGTCGTGCAGGGCGGCTTGATGCATGGTAAGACCTCACCCGT
CACGCACGACGACAGCGGCGTTTTCGCTGGCTTGCCCTCGCCCTTCACCGCTACCCGCTATCATTCGTTGGTGGTGCAAG
ACATTCCCGAGGTTCTCACCGTCAATGCAACCAGCGAAACACCCGGCCTCGACGGCACCATGGTGATGGGTTTCCGGCAC
CGGGACCTGCCCATCCACGGCGTGCAGTTCCACCCGGAAAGCATCGCCACCGAGCACGGCCATGACCTGCTTGCCAACTT
CCTGTCGCTGTGCGGCATTTCCCCTGCCCGCACAGAAAAGGCACCCGCATGA

Upstream 100 bases:

>100_bases
CGATGAGGAGGTCTATGTTGTGATGGGAAAGAAGTTCAAATATGCGCCCCTTTCACACGCCATTGCAGAGATCTGTCTTA
GAGAGGACTGTATCTAGTCC

Downstream 100 bases:

>100_bases
AAACCCTCCCCCTCGCCGTCCCGCATATGAGCCAGGACGAGGCCGAAGAGGTGTTCGGCTGGATCCTCGACGGCGAAGCC
TCGGAAGAGGAAATCGCGCG

Product: anthranilate/para-aminobenzoate synthase component II

Products: NA

Alternate protein names: ADC synthase [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MILVIDNYDSFTFNLVHYLMELGAEVRVERNDALTAADAIASGAKGILISPGPCTPDEAGISLDLVGACADADMPLLGVC
LGHQAIGQYFGGRVVQGGLMHGKTSPVTHDDSGVFAGLPSPFTATRYHSLVVQDIPEVLTVNATSETPGLDGTMVMGFRH
RDLPIHGVQFHPESIATEHGHDLLANFLSLCGISPARTEKAPA

Sequences:

>Translated_203_residues
MILVIDNYDSFTFNLVHYLMELGAEVRVERNDALTAADAIASGAKGILISPGPCTPDEAGISLDLVGACADADMPLLGVC
LGHQAIGQYFGGRVVQGGLMHGKTSPVTHDDSGVFAGLPSPFTATRYHSLVVQDIPEVLTVNATSETPGLDGTMVMGFRH
RDLPIHGVQFHPESIATEHGHDLLANFLSLCGISPARTEKAPA
>Mature_203_residues
MILVIDNYDSFTFNLVHYLMELGAEVRVERNDALTAADAIASGAKGILISPGPCTPDEAGISLDLVGACADADMPLLGVC
LGHQAIGQYFGGRVVQGGLMHGKTSPVTHDDSGVFAGLPSPFTATRYHSLVVQDIPEVLTVNATSETPGLDGTMVMGFRH
RDLPIHGVQFHPESIATEHGHDLLANFLSLCGISPARTEKAPA

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=191, Percent_Identity=60.7329842931937, Blast_Score=224, Evalue=5e-60,
Organism=Escherichia coli, GI1787517, Length=203, Percent_Identity=42.8571428571429, Blast_Score=136, Evalue=8e-34,
Organism=Saccharomyces cerevisiae, GI6322638, Length=206, Percent_Identity=41.2621359223301, Blast_Score=165, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6324361, Length=221, Percent_Identity=30.316742081448, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 21388; Mature: 21388

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVIDNYDSFTFNLVHYLMELGAEVRVERNDALTAADAIASGAKGILISPGPCTPDEAG
CEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCEEEECCCCCCCCCCC
ISLDLVGACADADMPLLGVCLGHQAIGQYFGGRVVQGGLMHGKTSPVTHDDSGVFAGLPS
CEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCEEEECCEECCCCCCCCCCCCCEEECCCC
PFTATRYHSLVVQDIPEVLTVNATSETPGLDGTMVMGFRHRDLPIHGVQFHPESIATEHG
CCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCCEEECCHHHCCCCC
HDLLANFLSLCGISPARTEKAPA
HHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MILVIDNYDSFTFNLVHYLMELGAEVRVERNDALTAADAIASGAKGILISPGPCTPDEAG
CEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCEEEECCCCCCCCCCC
ISLDLVGACADADMPLLGVCLGHQAIGQYFGGRVVQGGLMHGKTSPVTHDDSGVFAGLPS
CEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCEEEECCEECCCCCCCCCCCCCEEECCCC
PFTATRYHSLVVQDIPEVLTVNATSETPGLDGTMVMGFRHRDLPIHGVQFHPESIATEHG
CCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCCEEECCHHHCCCCC
HDLLANFLSLCGISPARTEKAPA
HHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6350604; 2403545; 9278503; 2546924; 8096767 [H]