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The map label for this gene is pip [H]

Identifier: 85374126

GI number: 85374126

Start: 1347971

End: 1348948

Strand: Direct

Name: pip [H]

Synonym: ELI_06495

Alternate gene names: 85374126

Gene position: 1347971-1348948 (Clockwise)

Preceding gene: 85374125

Following gene: 85374127

Centisome position: 44.16

GC content: 63.6

Gene sequence:

>978_bases
ATGGCGAACAGCAATATGCTCGATTACAAACGCACGCTCTATCCCGAGATCGAGCCTTACGAGACCGGCATGCTCGATGT
CGGCGAAGGCCATCAGCTCTATTACGAGCGCGTCGGCACACCGGGCGCCAAGCCGGCGGTGTTCCTGCATGGCGGGCCGG
GCGGCGGTATGGCACCCTCGCATCGCCGCCAGTGGGACCCCGAGCTCTACGACGTGCTGCTGTTCGACCAGCGCGGTTGC
GGCAAGTCGCTACCCTTTGCGGAAATCGAGCACAACGACACCTGGCGCATCGTCGCCGATATCGAGCGCCTGCGCGAAAT
GTGCGGCCACGAGGCGTGGCAGGTCTTCGGCGGAAGCTGGGGCGCGACGCTGGCGCTGGCCTACGCCCAGAAACATCCCG
AACGCACCACCGAGATCGTGCTGCGCGGGGTTTTCCTCGCCCGGCAGAACGAGAAGAGCTGGCTTTACCAGTACGGGGCG
AGCGAGATCATGGCCGAGCAGTGGGACGAATTCTCTGGCCATATTCCCGAGGCCGAACGCGACGACCTGGTCCAGGCTTA
TTATGCGCGCCTGACGAGCGACGACGAGCCAACGCGGCTGGCAGCGGCCAAGCAATGGTCCTTGTGGGAAGGAACCGTCG
CAACCTTGCTGCCCAATGCGGACTTGCTGGCGGATTTCGAGGATCCGGCGAAAGCCGTGCCCTTCGCCCGCATCTGCGCG
CGTTTCTTCCTCGAGAACTTCTATCTCGAGGAAGGGCAATTGCTGCGCGACATGCAGAGCATCGGGCATATCCCGACCAT
CATCGTGCAGGGCCGCCACGACATCTGCACCCCGCCGGGTGCGGCATGGGCGGTCAAGAAAGCGCATCCGGCAGCCGAGC
TGTGGATGGTGCACGACGCAGGCCACAGCGCAAGCGAACCGGGGATCGTGGACGGTCTGGTGCGCGCAACGGATCAATTT
GCCGATAAGTCAAAGTGA

Upstream 100 bases:

>100_bases
TCTATCTCGACGGCAATGTCTCAGGCCTATGGGACCCGGCGAACGACCGCATGGATGCCCGCGCGCCGATCGGCCCGATG
ATCGTGGTGGAGACCAGGTA

Downstream 100 bases:

>100_bases
AGAAAGCACGCCACAAAATCTCGCCGGAGAACTTTCCACCATATGCTTTTGCATTCTATGGGGTTGCGATTGACGAGGCA
GCACGCTTGGCTGTTCGTTC

Product: putative proline iminopeptidase protein

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MANSNMLDYKRTLYPEIEPYETGMLDVGEGHQLYYERVGTPGAKPAVFLHGGPGGGMAPSHRRQWDPELYDVLLFDQRGC
GKSLPFAEIEHNDTWRIVADIERLREMCGHEAWQVFGGSWGATLALAYAQKHPERTTEIVLRGVFLARQNEKSWLYQYGA
SEIMAEQWDEFSGHIPEAERDDLVQAYYARLTSDDEPTRLAAAKQWSLWEGTVATLLPNADLLADFEDPAKAVPFARICA
RFFLENFYLEEGQLLRDMQSIGHIPTIIVQGRHDICTPPGAAWAVKKAHPAAELWMVHDAGHSASEPGIVDGLVRATDQF
ADKSK

Sequences:

>Translated_325_residues
MANSNMLDYKRTLYPEIEPYETGMLDVGEGHQLYYERVGTPGAKPAVFLHGGPGGGMAPSHRRQWDPELYDVLLFDQRGC
GKSLPFAEIEHNDTWRIVADIERLREMCGHEAWQVFGGSWGATLALAYAQKHPERTTEIVLRGVFLARQNEKSWLYQYGA
SEIMAEQWDEFSGHIPEAERDDLVQAYYARLTSDDEPTRLAAAKQWSLWEGTVATLLPNADLLADFEDPAKAVPFARICA
RFFLENFYLEEGQLLRDMQSIGHIPTIIVQGRHDICTPPGAAWAVKKAHPAAELWMVHDAGHSASEPGIVDGLVRATDQF
ADKSK
>Mature_324_residues
ANSNMLDYKRTLYPEIEPYETGMLDVGEGHQLYYERVGTPGAKPAVFLHGGPGGGMAPSHRRQWDPELYDVLLFDQRGCG
KSLPFAEIEHNDTWRIVADIERLREMCGHEAWQVFGGSWGATLALAYAQKHPERTTEIVLRGVFLARQNEKSWLYQYGAS
EIMAEQWDEFSGHIPEAERDDLVQAYYARLTSDDEPTRLAAAKQWSLWEGTVATLLPNADLLADFEDPAKAVPFARICAR
FFLENFYLEEGQLLRDMQSIGHIPTIIVQGRHDICTPPGAAWAVKKAHPAAELWMVHDAGHSASEPGIVDGLVRATDQFA
DKSK

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 36486; Mature: 36355

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANSNMLDYKRTLYPEIEPYETGMLDVGEGHQLYYERVGTPGAKPAVFLHGGPGGGMAPS
CCCCCCCHHHHHHCCCCCCCCCCCEECCCCCHHHHHHCCCCCCCCEEEEECCCCCCCCCC
HRRQWDPELYDVLLFDQRGCGKSLPFAEIEHNDTWRIVADIERLREMCGHEAWQVFGGSW
CCCCCCHHHHHEEEECCCCCCCCCCCCEECCCCCEEHHHHHHHHHHHHCCHHHHHHCCCC
GATLALAYAQKHPERTTEIVLRGVFLARQNEKSWLYQYGASEIMAEQWDEFSGHIPEAER
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHHHCCCCCCCCH
DDLVQAYYARLTSDDEPTRLAAAKQWSLWEGTVATLLPNADLLADFEDPAKAVPFARICA
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHCCCCHHEECCCCCHHHCCHHHHHH
RFFLENFYLEEGQLLRDMQSIGHIPTIIVQGRHDICTPPGAAWAVKKAHPAAELWMVHDA
HHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEECCCCCCEEEEEEECC
GHSASEPGIVDGLVRATDQFADKSK
CCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ANSNMLDYKRTLYPEIEPYETGMLDVGEGHQLYYERVGTPGAKPAVFLHGGPGGGMAPS
CCCCCCHHHHHHCCCCCCCCCCCEECCCCCHHHHHHCCCCCCCCEEEEECCCCCCCCCC
HRRQWDPELYDVLLFDQRGCGKSLPFAEIEHNDTWRIVADIERLREMCGHEAWQVFGGSW
CCCCCCHHHHHEEEECCCCCCCCCCCCEECCCCCEEHHHHHHHHHHHHCCHHHHHHCCCC
GATLALAYAQKHPERTTEIVLRGVFLARQNEKSWLYQYGASEIMAEQWDEFSGHIPEAER
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHHHCCCCCCCCH
DDLVQAYYARLTSDDEPTRLAAAKQWSLWEGTVATLLPNADLLADFEDPAKAVPFARICA
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHCCCCHHEECCCCCHHHCCHHHHHH
RFFLENFYLEEGQLLRDMQSIGHIPTIIVQGRHDICTPPGAAWAVKKAHPAAELWMVHDA
HHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEECCCCCCEEEEEEECC
GHSASEPGIVDGLVRATDQFADKSK
CCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]