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The map label for this gene is ppiD [H]

Identifier: 85374123

GI number: 85374123

Start: 1343673

End: 1345616

Strand: Direct

Name: ppiD [H]

Synonym: ELI_06480

Alternate gene names: 85374123

Gene position: 1343673-1345616 (Clockwise)

Preceding gene: 85374118

Following gene: 85374124

Centisome position: 44.02

GC content: 65.33

Gene sequence:

>1944_bases
ATGATCAATTCGTTCCGCAGATTTTTTCAGTCGAAGATCGGCATCGGCATCTTCGTCGGATTCCTCGCGCTCATCGCGAT
TGCCTTTGCCGGGGCGGACGTCTCCAGCACCGGCACGTTCGGCGGCGTATCGGGCGGCGACCGGGTCGCTGTGGTGGGCG
AGCAGAAAGTCGGGACTGCCGAGCTGAGCCGGGCGGCATCGAATGCCCTGGACCAGTTGAGGCAGAACGATCCGACGCTG
TCGATGCCGGCTTTCATCGACCAGGGCGGGCTCGAAAGGGTCGTCGAAACCCTGCTAGACCGGATCGCGATCGCGGAATT
CGGCCGGAAATACGGCATGCGCGCGGGCGACAATCTGGTGAATAGCGAAATTCGCAGGATCCCGGTATTCCGCGGTGCCG
ACGGCAATTTCGACGAGGAAACCTATCGTGCCGCCATCGCGCGCCAGGGCCTGACCGATGCCGTCGTGCGCGACGATCTC
GGCGACGGCCTGATCGCCCAGCAGGTCCTGGTGCCGGGGAGTTTCGGTGCGACGATCCCCGACAAGCTGGCGAGCAGGTA
TGCTGCGCTGTTCAAGGAACGTCGCCGCGGTGCCATCGCGCTAATCCCGAGCACCTCGTTCGCGCCTGACGGCGAGCCGA
CCGATGCGCAGGTTCAAGCCTATTACAATGCCAACAAGGGCGATTACATCCGGCCCGAGCGCCGCGTTATTCGCTATGCG
ACGTTCGGCGAATCGGCCGTCGCCGATGTCGGCACGCCGACCGCTGCGGAGATCGCCAATCGCTACGAACAGGATGCCTC
GCGCTATGCCGCGAGCGAAGAACGTACGCTCACGCAGTTGATCGTGCCCACCCAGCAGGCGGCACAGACGTTCCGCGATC
GCGTTGCCGGTGGTGCCTCGCTCGAAACGGTGGCGCGCGAAGCCGGGCTGGAAGCGCAGCAGATCGGCCCCATCGACCGC
AGCGAGTACGGCGCGCAGGCTTCCGCTCAGGTTGCGCAGGCGGTGTTCGGTACCGCGCGCGGCCAGGTCGCCCCCGTCGC
GCGCAGCGGCCTCGGCTGGCACGTGGTGCGGGTCGACGATGTCAATCGCATCGAAGGACGGTCGCTGGCGCAGGCGCGCG
AAGAGATCGTGTCGACTCTCACGCAAGAACGGCGCCGCCGCGCCTTCAACGAATTGGCCGAAAGTATCGAAGACCGCTTC
GCCGATGGCGAATCGCTCGCCGATGTCGCAGCGGAAGTCGGGGCCGAAGTGCAAACGACGCGTCCGCTCACCGGCGCCGG
CATCGTCTATGGCACGCAGAACGAGCAGGCCCCGGAAATCCTGCGCCGCGCCCTCGCGACGGCGTTCCAGATGGAAGAAG
GCGAACCGCAACTGACCGAGGCGGTACCGGGAGAAACCTTCATGCTGTTCGAAGCCAGCGACATTACGCCATCGGCCCCG
GCTCCGCTCGCGGAGATTCGCGATACGGTGGTGGCCGACTGGAAGCGTGCCGAAGGGGCAAAGCGAGCGCGCGCGGCTGC
CGACCGGGTGCTGAAACGTCTTGGCGATGGCCAGTCGCTGGCGGCCGCCGTCCGCGCGGAGGACGCCAGCATTCCCCCAA
TCGACCAGGTCAATTTGACTCGCGAACAGCTTGTCCAGCGCGGCGAGCGAGGGGTGCCGGCACCGCTCGCCCTGCTATTC
AGCATGGCCCAGGGCACCGAAAAGAAACTGGAGGCACCGCGCAATATCGGGTGGTTTATCGTCGATCTGGATTCGATCGA
GGCCGGTGTCGTCGGCCGGGACGACCCGCTGTTCCGCCAGGCAAAATCGCAATTCGGGCAGACTTTCGGCCAGGAATATG
GCGAGCAGTTGCGGCTTGCGATCCGCAACGACGTCACCATCGAGCGCAACGAAGCTGCCATCGAAGCAGTCCGCCGTCAG
CTCACCGGCGAAGCCCAGCAATAG

Upstream 100 bases:

>100_bases
CACCTGTTGCGGGAGGGTCGCAGCCTCTCTAAAGCGGGCGGCATTATCGGTGTGGCCCCCGCCGCGCCGGCTTTCGACCA
CATTTGGACCTGTCTTTTCC

Downstream 100 bases:

>100_bases
GAGGCGGCAACTGTCTGGCGCGGGCCTCCATAATCGCGATGCCGCGCTGGGGCAGCTCGCTGGCGGTGCGCCCGCGCTGG
TGTGGCGCGAAGTGGTTGCC

Product: peptidyl-prolyl isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 647; Mature: 647

Protein sequence:

>647_residues
MINSFRRFFQSKIGIGIFVGFLALIAIAFAGADVSSTGTFGGVSGGDRVAVVGEQKVGTAELSRAASNALDQLRQNDPTL
SMPAFIDQGGLERVVETLLDRIAIAEFGRKYGMRAGDNLVNSEIRRIPVFRGADGNFDEETYRAAIARQGLTDAVVRDDL
GDGLIAQQVLVPGSFGATIPDKLASRYAALFKERRRGAIALIPSTSFAPDGEPTDAQVQAYYNANKGDYIRPERRVIRYA
TFGESAVADVGTPTAAEIANRYEQDASRYAASEERTLTQLIVPTQQAAQTFRDRVAGGASLETVAREAGLEAQQIGPIDR
SEYGAQASAQVAQAVFGTARGQVAPVARSGLGWHVVRVDDVNRIEGRSLAQAREEIVSTLTQERRRRAFNELAESIEDRF
ADGESLADVAAEVGAEVQTTRPLTGAGIVYGTQNEQAPEILRRALATAFQMEEGEPQLTEAVPGETFMLFEASDITPSAP
APLAEIRDTVVADWKRAEGAKRARAAADRVLKRLGDGQSLAAAVRAEDASIPPIDQVNLTREQLVQRGERGVPAPLALLF
SMAQGTEKKLEAPRNIGWFIVDLDSIEAGVVGRDDPLFRQAKSQFGQTFGQEYGEQLRLAIRNDVTIERNEAAIEAVRRQ
LTGEAQQ

Sequences:

>Translated_647_residues
MINSFRRFFQSKIGIGIFVGFLALIAIAFAGADVSSTGTFGGVSGGDRVAVVGEQKVGTAELSRAASNALDQLRQNDPTL
SMPAFIDQGGLERVVETLLDRIAIAEFGRKYGMRAGDNLVNSEIRRIPVFRGADGNFDEETYRAAIARQGLTDAVVRDDL
GDGLIAQQVLVPGSFGATIPDKLASRYAALFKERRRGAIALIPSTSFAPDGEPTDAQVQAYYNANKGDYIRPERRVIRYA
TFGESAVADVGTPTAAEIANRYEQDASRYAASEERTLTQLIVPTQQAAQTFRDRVAGGASLETVAREAGLEAQQIGPIDR
SEYGAQASAQVAQAVFGTARGQVAPVARSGLGWHVVRVDDVNRIEGRSLAQAREEIVSTLTQERRRRAFNELAESIEDRF
ADGESLADVAAEVGAEVQTTRPLTGAGIVYGTQNEQAPEILRRALATAFQMEEGEPQLTEAVPGETFMLFEASDITPSAP
APLAEIRDTVVADWKRAEGAKRARAAADRVLKRLGDGQSLAAAVRAEDASIPPIDQVNLTREQLVQRGERGVPAPLALLF
SMAQGTEKKLEAPRNIGWFIVDLDSIEAGVVGRDDPLFRQAKSQFGQTFGQEYGEQLRLAIRNDVTIERNEAAIEAVRRQ
LTGEAQQ
>Mature_647_residues
MINSFRRFFQSKIGIGIFVGFLALIAIAFAGADVSSTGTFGGVSGGDRVAVVGEQKVGTAELSRAASNALDQLRQNDPTL
SMPAFIDQGGLERVVETLLDRIAIAEFGRKYGMRAGDNLVNSEIRRIPVFRGADGNFDEETYRAAIARQGLTDAVVRDDL
GDGLIAQQVLVPGSFGATIPDKLASRYAALFKERRRGAIALIPSTSFAPDGEPTDAQVQAYYNANKGDYIRPERRVIRYA
TFGESAVADVGTPTAAEIANRYEQDASRYAASEERTLTQLIVPTQQAAQTFRDRVAGGASLETVAREAGLEAQQIGPIDR
SEYGAQASAQVAQAVFGTARGQVAPVARSGLGWHVVRVDDVNRIEGRSLAQAREEIVSTLTQERRRRAFNELAESIEDRF
ADGESLADVAAEVGAEVQTTRPLTGAGIVYGTQNEQAPEILRRALATAFQMEEGEPQLTEAVPGETFMLFEASDITPSAP
APLAEIRDTVVADWKRAEGAKRARAAADRVLKRLGDGQSLAAAVRAEDASIPPIDQVNLTREQLVQRGERGVPAPLALLF
SMAQGTEKKLEAPRNIGWFIVDLDSIEAGVVGRDDPLFRQAKSQFGQTFGQEYGEQLRLAIRNDVTIERNEAAIEAVRRQ
LTGEAQQ

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=538, Percent_Identity=23.4200743494424, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 69868; Mature: 69868

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINSFRRFFQSKIGIGIFVGFLALIAIAFAGADVSSTGTFGGVSGGDRVAVVGEQKVGTA
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCHH
ELSRAASNALDQLRQNDPTLSMPAFIDQGGLERVVETLLDRIAIAEFGRKYGMRAGDNLV
HHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
NSEIRRIPVFRGADGNFDEETYRAAIARQGLTDAVVRDDLGDGLIAQQVLVPGSFGATIP
HHHHHHCCEEECCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHCCCCCCCCCH
DKLASRYAALFKERRRGAIALIPSTSFAPDGEPTDAQVQAYYNANKGDYIRPERRVIRYA
HHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHEEEEE
TFGESAVADVGTPTAAEIANRYEQDASRYAASEERTLTQLIVPTQQAAQTFRDRVAGGAS
ECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCH
LETVAREAGLEAQQIGPIDRSEYGAQASAQVAQAVFGTARGQVAPVARSGLGWHVVRVDD
HHHHHHHHCCCHHHCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEEECC
VNRIEGRSLAQAREEIVSTLTQERRRRAFNELAESIEDRFADGESLADVAAEVGAEVQTT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
RPLTGAGIVYGTQNEQAPEILRRALATAFQMEEGEPQLTEAVPGETFMLFEASDITPSAP
CCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCEEEEEEECCCCCCCC
APLAEIRDTVVADWKRAEGAKRARAAADRVLKRLGDGQSLAAAVRAEDASIPPIDQVNLT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCC
REQLVQRGERGVPAPLALLFSMAQGTEKKLEAPRNIGWFIVDLDSIEAGVVGRDDPLFRQ
HHHHHHCCCCCCCHHHHHHHHHHCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHH
AKSQFGQTFGQEYGEQLRLAIRNDVTIERNEAAIEAVRRQLTGEAQQ
HHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MINSFRRFFQSKIGIGIFVGFLALIAIAFAGADVSSTGTFGGVSGGDRVAVVGEQKVGTA
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCHH
ELSRAASNALDQLRQNDPTLSMPAFIDQGGLERVVETLLDRIAIAEFGRKYGMRAGDNLV
HHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
NSEIRRIPVFRGADGNFDEETYRAAIARQGLTDAVVRDDLGDGLIAQQVLVPGSFGATIP
HHHHHHCCEEECCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHCCCCCCCCCH
DKLASRYAALFKERRRGAIALIPSTSFAPDGEPTDAQVQAYYNANKGDYIRPERRVIRYA
HHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHEEEEE
TFGESAVADVGTPTAAEIANRYEQDASRYAASEERTLTQLIVPTQQAAQTFRDRVAGGAS
ECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCH
LETVAREAGLEAQQIGPIDRSEYGAQASAQVAQAVFGTARGQVAPVARSGLGWHVVRVDD
HHHHHHHHCCCHHHCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEEECC
VNRIEGRSLAQAREEIVSTLTQERRRRAFNELAESIEDRFADGESLADVAAEVGAEVQTT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
RPLTGAGIVYGTQNEQAPEILRRALATAFQMEEGEPQLTEAVPGETFMLFEASDITPSAP
CCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCEEEEEEECCCCCCCC
APLAEIRDTVVADWKRAEGAKRARAAADRVLKRLGDGQSLAAAVRAEDASIPPIDQVNLT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCC
REQLVQRGERGVPAPLALLFSMAQGTEKKLEAPRNIGWFIVDLDSIEAGVVGRDDPLFRQ
HHHHHHCCCCCCCHHHHHHHHHHCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHH
AKSQFGQTFGQEYGEQLRLAIRNDVTIERNEAAIEAVRRQLTGEAQQ
HHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]