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The map label for this gene is ctaE [H]

Identifier: 85373377

GI number: 85373377

Start: 586096

End: 586959

Strand: Direct

Name: ctaE [H]

Synonym: ELI_02750

Alternate gene names: 85373377

Gene position: 586096-586959 (Clockwise)

Preceding gene: 85373376

Following gene: 85373378

Centisome position: 19.2

GC content: 61.92

Gene sequence:

>864_bases
ATGGCCGGTGCCAAGAACCACGACTATCATATTCTCGAACCCGATATCTGGCCGCTGATCGGCTCGATCTCGGCGCTGAC
ATTTACCACCGGCATGGTGCTGTTCATGCACGAAATGCCGAGTTGGCAGATCGTTCTGGGCCTCGGCATCGCGGGGCTGA
TCGCCACCTTCTTCTCGTGGTGGTCGAACGTCGTGAAGGAAGCTCACCGCGGCGATCACACCCCGGTCGTGCAATTGCAC
ATGCGCTACGGCATGATCCTGTTCATCGCTTCCGAAGTGATGTTCTTCGTCGGCTGGTTCTGGGCCTTCTTCGATTTTGC
ACTTTTCCCAGCGCCGATCCGCGAATTGAGCGACAATGTCTGGGAGAATCTGATCGGCCAGGAAGGCGCGGCCGCGCTGG
CGACTTTCCCGCCCGAGGGCATCGAAGTCCTCGACCCGTTCAGCCTCCCGCTGCTCAATACGCTGATCCTGCTGTGCTCG
GGCACCACCGTGACCTGGGCGCACCACGCGCTGCTGCATGGGGACCGTGACGGGCTGAAGAAGGGCCTATGGGCGACCGT
CGCGCTGGGCGCGCTGTTCACCGCCATCCAGGCCTACGAGTATGGCCTCGCGCCGTTCGGCTTCGGTGGCAACACCTACA
GCTCGGCCTTCTACATGGCGACCGGCTTTCACGGCTTCCACGTCCTCGTCGGCACGATCTTCCTGATCGTCTGTCTGGTG
CGTGCCTACAAGGGCCACTTCACTCCGCGCCAGCATTTCGGCTTCGAAGCCGCTGCCTGGTACTGGCACTTCGTCGACGT
GGTGTGGCTGTTCCTGTTCGTCGCCGTCTACATTTGGGGCGGCTGGGGTGCGCCGGTTCACTGA

Upstream 100 bases:

>100_bases
AGAAGAAGGAGCGCGGCGAATAGCCGCCTCAACCCCCTAGACCCGCCGCCCGGGGGGCTTTAAGGGCAGCGACGACGGAA
CGACTAACGGGAAACGATTC

Downstream 100 bases:

>100_bases
TGATCGGCCGCGATGCGGCTGACACGAAAGGGCGGCCCGCAATTCGCGCGGCCGCCCTTTTCGCTTCCTGACAGGACAAT
GACCTGATGCCCAAGTTCCC

Product: cytochrome C oxidase subunit III

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III; Oxidase aa(3) subunit 3 [H]

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MAGAKNHDYHILEPDIWPLIGSISALTFTTGMVLFMHEMPSWQIVLGLGIAGLIATFFSWWSNVVKEAHRGDHTPVVQLH
MRYGMILFIASEVMFFVGWFWAFFDFALFPAPIRELSDNVWENLIGQEGAAALATFPPEGIEVLDPFSLPLLNTLILLCS
GTTVTWAHHALLHGDRDGLKKGLWATVALGALFTAIQAYEYGLAPFGFGGNTYSSAFYMATGFHGFHVLVGTIFLIVCLV
RAYKGHFTPRQHFGFEAAAWYWHFVDVVWLFLFVAVYIWGGWGAPVH

Sequences:

>Translated_287_residues
MAGAKNHDYHILEPDIWPLIGSISALTFTTGMVLFMHEMPSWQIVLGLGIAGLIATFFSWWSNVVKEAHRGDHTPVVQLH
MRYGMILFIASEVMFFVGWFWAFFDFALFPAPIRELSDNVWENLIGQEGAAALATFPPEGIEVLDPFSLPLLNTLILLCS
GTTVTWAHHALLHGDRDGLKKGLWATVALGALFTAIQAYEYGLAPFGFGGNTYSSAFYMATGFHGFHVLVGTIFLIVCLV
RAYKGHFTPRQHFGFEAAAWYWHFVDVVWLFLFVAVYIWGGWGAPVH
>Mature_286_residues
AGAKNHDYHILEPDIWPLIGSISALTFTTGMVLFMHEMPSWQIVLGLGIAGLIATFFSWWSNVVKEAHRGDHTPVVQLHM
RYGMILFIASEVMFFVGWFWAFFDFALFPAPIRELSDNVWENLIGQEGAAALATFPPEGIEVLDPFSLPLLNTLILLCSG
TTVTWAHHALLHGDRDGLKKGLWATVALGALFTAIQAYEYGLAPFGFGGNTYSSAFYMATGFHGFHVLVGTIFLIVCLVR
AYKGHFTPRQHFGFEAAAWYWHFVDVVWLFLFVAVYIWGGWGAPVH

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=278, Percent_Identity=46.4028776978417, Blast_Score=225, Evalue=3e-59,
Organism=Escherichia coli, GI1786633, Length=144, Percent_Identity=31.9444444444444, Blast_Score=62, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6226542, Length=277, Percent_Identity=36.101083032491, Blast_Score=157, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 32091; Mature: 31959

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGAKNHDYHILEPDIWPLIGSISALTFTTGMVLFMHEMPSWQIVLGLGIAGLIATFFSW
CCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHH
WSNVVKEAHRGDHTPVVQLHMRYGMILFIASEVMFFVGWFWAFFDFALFPAPIRELSDNV
HHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
WENLIGQEGAAALATFPPEGIEVLDPFSLPLLNTLILLCSGTTVTWAHHALLHGDRDGLK
HHHHHCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHH
KGLWATVALGALFTAIQAYEYGLAPFGFGGNTYSSAFYMATGFHGFHVLVGTIFLIVCLV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHH
RAYKGHFTPRQHFGFEAAAWYWHFVDVVWLFLFVAVYIWGGWGAPVH
HHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AGAKNHDYHILEPDIWPLIGSISALTFTTGMVLFMHEMPSWQIVLGLGIAGLIATFFSW
CCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHH
WSNVVKEAHRGDHTPVVQLHMRYGMILFIASEVMFFVGWFWAFFDFALFPAPIRELSDNV
HHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
WENLIGQEGAAALATFPPEGIEVLDPFSLPLLNTLILLCSGTTVTWAHHALLHGDRDGLK
HHHHHCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHH
KGLWATVALGALFTAIQAYEYGLAPFGFGGNTYSSAFYMATGFHGFHVLVGTIFLIVCLV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHH
RAYKGHFTPRQHFGFEAAAWYWHFVDVVWLFLFVAVYIWGGWGAPVH
HHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3019767; 2832167; 7651515 [H]