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The map label for this gene is algR [H]

Identifier: 84625436

GI number: 84625436

Start: 4273315

End: 4274052

Strand: Reverse

Name: algR [H]

Synonym: XOO_3779

Alternate gene names: 84625436

Gene position: 4274052-4273315 (Counterclockwise)

Preceding gene: 84625437

Following gene: 84625435

Centisome position: 86.52

GC content: 67.07

Gene sequence:

>738_bases
ATGACGGCCACGCAAGTGCGGGTGCTAATCGCCGATGACGAGCCACTGGCGCGCGAGCGCCTGCGCATGCTGCTGGGCGA
GCATCCGCAGGTCGAGGTGATTGGCGAGGCCGAAAACGGCCAGCAGGTCGTGCAGCAGTGCGAACACCTGCATCCGGATC
TGGTGCTGCTGGACATCGCCATGCCCGGTGTCGACGGCTTGGGAACCGCGCGCTTGCTGCGGCAGAGCCAGCCGCCGCCG
GCGGTGGTGTTCTGCACCGCCTACGACCAGCATGCACTGTCCGCGTTCGACGCGGCGGCGCTGGATTACCTGATGAAACC
GGTGCGCCCGGAACGGCTGGCCTCCGCCCTGGAAAAGGTCGCCACCTTCCTCGCCGGCCGCGCGCCCGGCACCGCGCCCA
GGCCGGTGCGCACCCATCTGTGCGCACGCCTGCGCGGTAGCCTGCGGCTGATCGCCATCGGCGACATCCGTTACCTGCAG
GCCGAAGAAAAGTACGTCATCGTCCATCACACCCGCGGCGAGGACCTGATCGAAGAGTCGCTCAAATCGCTGGAAGACGA
ATTCGCCGACCGTCTGGTGCGCATTCACCGCAATTGCCTGGTCGCCCGCGACGAGCTGGTGGAACTGCGCCGCAGCGGCG
ATGGCCAGGTGCATGCGGTGCTGCGCAACGTACCGCAGACCCTGGAAGTGAGTCGGCGCTGTGTCGCCAGCCTGCGCGAT
CAATTACGCCAACTGTGA

Upstream 100 bases:

>100_bases
CGGGGCACGGATTGCGGCCAGCTGGGCTGAAGGCTACTATGCCTGTGAGATCACATTGCCGCTGCCGTGAGGGGAAAGTC
ACCGCAGCCAGGGGGAGTCC

Downstream 100 bases:

>100_bases
GTTCCGCGCCGGCTCCGCGATAATGCTGGAATGACCACGCTCCGCATCGCTACCCGCAAAAGCCCGCTCGCCCTCTGGCA
GAGCGAACACGTCGCCGCCG

Product: two-component system regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MTATQVRVLIADDEPLARERLRMLLGEHPQVEVIGEAENGQQVVQQCEHLHPDLVLLDIAMPGVDGLGTARLLRQSQPPP
AVVFCTAYDQHALSAFDAAALDYLMKPVRPERLASALEKVATFLAGRAPGTAPRPVRTHLCARLRGSLRLIAIGDIRYLQ
AEEKYVIVHHTRGEDLIEESLKSLEDEFADRLVRIHRNCLVARDELVELRRSGDGQVHAVLRNVPQTLEVSRRCVASLRD
QLRQL

Sequences:

>Translated_245_residues
MTATQVRVLIADDEPLARERLRMLLGEHPQVEVIGEAENGQQVVQQCEHLHPDLVLLDIAMPGVDGLGTARLLRQSQPPP
AVVFCTAYDQHALSAFDAAALDYLMKPVRPERLASALEKVATFLAGRAPGTAPRPVRTHLCARLRGSLRLIAIGDIRYLQ
AEEKYVIVHHTRGEDLIEESLKSLEDEFADRLVRIHRNCLVARDELVELRRSGDGQVHAVLRNVPQTLEVSRRCVASLRD
QLRQL
>Mature_244_residues
TATQVRVLIADDEPLARERLRMLLGEHPQVEVIGEAENGQQVVQQCEHLHPDLVLLDIAMPGVDGLGTARLLRQSQPPPA
VVFCTAYDQHALSAFDAAALDYLMKPVRPERLASALEKVATFLAGRAPGTAPRPVRTHLCARLRGSLRLIAIGDIRYLQA
EEKYVIVHHTRGEDLIEESLKSLEDEFADRLVRIHRNCLVARDELVELRRSGDGQVHAVLRNVPQTLEVSRRCVASLRDQ
LRQL

Specific function: Positive regulator of the algD gene, which codes for a GDP-mannose dehydrogenase, a key step enzyme in the alginate biosynthesis pathway [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082052, Length=240, Percent_Identity=34.1666666666667, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788724, Length=247, Percent_Identity=28.7449392712551, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1788222, Length=117, Percent_Identity=32.4786324786325, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788521, Length=117, Percent_Identity=35.8974358974359, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787473, Length=185, Percent_Identity=35.1351351351351, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 27385; Mature: 27254

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATQVRVLIADDEPLARERLRMLLGEHPQVEVIGEAENGQQVVQQCEHLHPDLVLLDIA
CCCCEEEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEEE
MPGVDGLGTARLLRQSQPPPAVVFCTAYDQHALSAFDAAALDYLMKPVRPERLASALEKV
CCCCCCCHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ATFLAGRAPGTAPRPVRTHLCARLRGSLRLIAIGDIRYLQAEEKYVIVHHTRGEDLIEES
HHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEEECCEEEEECCCCEEEEEECCCHHHHHHH
LKSLEDEFADRLVRIHRNCLVARDELVELRRSGDGQVHAVLRNVPQTLEVSRRCVASLRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHH
QLRQL
HHHCC
>Mature Secondary Structure 
TATQVRVLIADDEPLARERLRMLLGEHPQVEVIGEAENGQQVVQQCEHLHPDLVLLDIA
CCCEEEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEEE
MPGVDGLGTARLLRQSQPPPAVVFCTAYDQHALSAFDAAALDYLMKPVRPERLASALEKV
CCCCCCCHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ATFLAGRAPGTAPRPVRTHLCARLRGSLRLIAIGDIRYLQAEEKYVIVHHTRGEDLIEES
HHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEEECCEEEEECCCCEEEEEECCCHHHHHHH
LKSLEDEFADRLVRIHRNCLVARDELVELRRSGDGQVHAVLRNVPQTLEVSRRCVASLRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHH
QLRQL
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2493441; 10984043; 2544550; 8159168 [H]