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The map label for this gene is mrdB [H]

Identifier: 84625401

GI number: 84625401

Start: 4235854

End: 4236972

Strand: Reverse

Name: mrdB [H]

Synonym: XOO_3744

Alternate gene names: 84625401

Gene position: 4236972-4235854 (Counterclockwise)

Preceding gene: 84625402

Following gene: 84625400

Centisome position: 85.76

GC content: 64.7

Gene sequence:

>1119_bases
TTGAGCGACATCCTGCGCTGGTTGGTTGACATGGCCGCGCGCTTTACGCGCAGCCTGGACTGGGTGCTGTGCCTGGCGCT
GGGCGGGCTGATGGCGATCGGCCTGTCGGTGCTCAAAAGCGCCGGTGGCACTGCCAACGGCCAGCACCTGTTGCAGGCGC
AAGCCATCCGCTTCGTCATCGGCATCGCGGCGATGTGGGGCATTTCGCGCATGTCGGTGCTGCGTCTGCGCGCCTGGACA
CCGTGGGTGTATGGCTTGTCGATGCTGCCGCTGTTGGCGGTCTTCGCGCTGGGCACCGGTAAGTACGGCCGCCAGTGGCT
GGATCTGAAAGTGTTTTACCTGCAGCCGGCCGAGCTACTCAAGATCAGCCTGCCGATGATGGCGGCCTGGTACCTGCATC
GCATGCCGCTGCCGCCGCGCATTTCCACCGTGTTGGTGACCGGGATGATTATCGGCGTGCCCACCGCGCTGATCATGCTG
CAGCCGGACTTCGGCACCGGTGTGTTGATCGCGGCCAGCGGCGTGTTCGTGCTGCTGCTGGCCGGCTTGCCGTGGTGGTG
GGTGGCCGTCGGCGTGGGCGGTGTGTCTGCGGCTGCGCCGGTGGCGTGGTTCTGGCTGCTGCGGCCGTACCAGAAGGACC
GCATCATGATGTTCCTCAACCCCGAGAACGACGCGCTCGGCGCAGGCTGGAACATCATCCAGTCCAAGATCGCGATTGGC
TCGGGCGGGTTGAACGGCAAGGGCTGGGGCCTGGGCTCGCAATCGCATCTGAACTTCATTCCCGAACAGACCACCGACTT
TGCGTTTTCGGTGCTTAGCGAAGAATTTGGCTGGATCGGCGTGGCCACCGTGCTGACCTTGTATCTCATCGTCATCGGTC
GCTGCCTGTGGATCGCATCGCAGGCGCGCGACACCTATTCGCGCCTGGTTGCCGGCGCCACCGGCCTGGCTTTTTTCGTC
TATGTCGTGGTCAACGGCGGCATGATCTCCGGCGTGCTGCCGGTGGTGGGCGTGCCGATGCCGCTGATGAGTTACGGCGG
CACCTCGGCGGTATCGTTGCTGGCCGGGCTGGGGTTGGTCATGGCAGTGAAGTCGCATCGCCCGGTGCATGGGTACTGA

Upstream 100 bases:

>100_bases
TGCCGGTGGTGGTCGGACAGACCGCCGTTGCGCTTGACCCCAACACGCCCGCGCAACCGGTGGTGCCGGATGTGCCGGAC
GCGGTGCAGGAGACCGACCA

Downstream 100 bases:

>100_bases
GCCGTCCCGAAAATAGGCCGTTCAAGCCCCGATGCTCGCAGCGACTGAAATAAGGCACTCGAAGATGTCCATGCCATCGC
GCCGAGCCGGCCAAGCGCGC

Product: rod shape-determining protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MSDILRWLVDMAARFTRSLDWVLCLALGGLMAIGLSVLKSAGGTANGQHLLQAQAIRFVIGIAAMWGISRMSVLRLRAWT
PWVYGLSMLPLLAVFALGTGKYGRQWLDLKVFYLQPAELLKISLPMMAAWYLHRMPLPPRISTVLVTGMIIGVPTALIML
QPDFGTGVLIAASGVFVLLLAGLPWWWVAVGVGGVSAAAPVAWFWLLRPYQKDRIMMFLNPENDALGAGWNIIQSKIAIG
SGGLNGKGWGLGSQSHLNFIPEQTTDFAFSVLSEEFGWIGVATVLTLYLIVIGRCLWIASQARDTYSRLVAGATGLAFFV
YVVVNGGMISGVLPVVGVPMPLMSYGGTSAVSLLAGLGLVMAVKSHRPVHGY

Sequences:

>Translated_372_residues
MSDILRWLVDMAARFTRSLDWVLCLALGGLMAIGLSVLKSAGGTANGQHLLQAQAIRFVIGIAAMWGISRMSVLRLRAWT
PWVYGLSMLPLLAVFALGTGKYGRQWLDLKVFYLQPAELLKISLPMMAAWYLHRMPLPPRISTVLVTGMIIGVPTALIML
QPDFGTGVLIAASGVFVLLLAGLPWWWVAVGVGGVSAAAPVAWFWLLRPYQKDRIMMFLNPENDALGAGWNIIQSKIAIG
SGGLNGKGWGLGSQSHLNFIPEQTTDFAFSVLSEEFGWIGVATVLTLYLIVIGRCLWIASQARDTYSRLVAGATGLAFFV
YVVVNGGMISGVLPVVGVPMPLMSYGGTSAVSLLAGLGLVMAVKSHRPVHGY
>Mature_371_residues
SDILRWLVDMAARFTRSLDWVLCLALGGLMAIGLSVLKSAGGTANGQHLLQAQAIRFVIGIAAMWGISRMSVLRLRAWTP
WVYGLSMLPLLAVFALGTGKYGRQWLDLKVFYLQPAELLKISLPMMAAWYLHRMPLPPRISTVLVTGMIIGVPTALIMLQ
PDFGTGVLIAASGVFVLLLAGLPWWWVAVGVGGVSAAAPVAWFWLLRPYQKDRIMMFLNPENDALGAGWNIIQSKIAIGS
GGLNGKGWGLGSQSHLNFIPEQTTDFAFSVLSEEFGWIGVATVLTLYLIVIGRCLWIASQARDTYSRLVAGATGLAFFVY
VVVNGGMISGVLPVVGVPMPLMSYGGTSAVSLLAGLGLVMAVKSHRPVHGY

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=327, Percent_Identity=45.8715596330275, Blast_Score=280, Evalue=2e-76,
Organism=Escherichia coli, GI1786277, Length=270, Percent_Identity=35.5555555555556, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40074; Mature: 39943

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDILRWLVDMAARFTRSLDWVLCLALGGLMAIGLSVLKSAGGTANGQHLLQAQAIRFVI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
GIAAMWGISRMSVLRLRAWTPWVYGLSMLPLLAVFALGTGKYGRQWLDLKVFYLQPAELL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCHHHH
KISLPMMAAWYLHRMPLPPRISTVLVTGMIIGVPTALIMLQPDFGTGVLIAASGVFVLLL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEHHHHHHHHHH
AGLPWWWVAVGVGGVSAAAPVAWFWLLRPYQKDRIMMFLNPENDALGAGWNIIQSKIAIG
HCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHEEC
SGGLNGKGWGLGSQSHLNFIPEQTTDFAFSVLSEEFGWIGVATVLTLYLIVIGRCLWIAS
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
QARDTYSRLVAGATGLAFFVYVVVNGGMISGVLPVVGVPMPLMSYGGTSAVSLLAGLGLV
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHH
MAVKSHRPVHGY
HHHHCCCCCCCC
>Mature Secondary Structure 
SDILRWLVDMAARFTRSLDWVLCLALGGLMAIGLSVLKSAGGTANGQHLLQAQAIRFVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
GIAAMWGISRMSVLRLRAWTPWVYGLSMLPLLAVFALGTGKYGRQWLDLKVFYLQPAELL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCHHHH
KISLPMMAAWYLHRMPLPPRISTVLVTGMIIGVPTALIMLQPDFGTGVLIAASGVFVLLL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEHHHHHHHHHH
AGLPWWWVAVGVGGVSAAAPVAWFWLLRPYQKDRIMMFLNPENDALGAGWNIIQSKIAIG
HCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHEEC
SGGLNGKGWGLGSQSHLNFIPEQTTDFAFSVLSEEFGWIGVATVLTLYLIVIGRCLWIAS
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
QARDTYSRLVAGATGLAFFVYVVVNGGMISGVLPVVGVPMPLMSYGGTSAVSLLAGLGLV
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHH
MAVKSHRPVHGY
HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]