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The map label for this gene is mraW [H]

Identifier: 84625268

GI number: 84625268

Start: 4086632

End: 4087675

Strand: Reverse

Name: mraW [H]

Synonym: XOO_3611

Alternate gene names: 84625268

Gene position: 4087675-4086632 (Counterclockwise)

Preceding gene: 84625269

Following gene: 84625267

Centisome position: 82.74

GC content: 66.57

Gene sequence:

>1044_bases
ATGCGCGGTGAAGCGCAGCCCGGTCACCCGGTGTCGCAGCCGCCGGCGGCCCATGTGCCGGTGCTCTACACGCAGGTTCT
GGATGGCCTGCAAGTGACCGAAAACGGAACCTATCTCGATGGCACGTTCGGACGTGGCGGACACGCACGCGGCGTGCTGG
AACACCTTGGCCCGGGAGGTCGACTGCTGGTGATGGACAAGGACCCTGACGCGATCGCAGTGGCCGAACAGACGTTCGGT
GGCGATGCACGCGTGTCCATCCATCGCGGCAGTTTCGCCGGGCTCGGTCAGGTGGTTGCCGCTGCCACTGTCGACGGCAT
CCTGCTGGATCTGGGCGTGTCTTCGCCGCAGCTGGATGTGGCCGGGCGCGGTTTCAGCTTCGGCAAGGACGGCCCGCTGG
ACATGCGCATGGACCCGGACAGCGGTCAGAGTGCGGCGCAGTGGCTGGCGCAGGCGACCGATCGCGAGATCGCCGATGTG
CTGTGGGCCTATGGCGAAGAACGCCAGAGCCGCCGCATCGCGCGCGCCATCGTGGCGCGCCGCGCCGAACAGCCGCTGCT
GCGCACCGCCCAACTGGCCGATCTGATCGCCTCGGTGATGCCGCGCGGCGACAGCAAGACCCACCCGGCCACACGCAGCT
TTCAGGCGATCCGCATCTACATCAATCGCGAACTCGACGATCTGGAAACCGGCCTGGATGCAGCGCTTGCCGCGCTCAAG
CCCGGCGGCCGGCTGGCGGTGATCAGCTTCCATTCGCTGGAAGATCGCATCGTCAAACAATTCATGGCCCGCTACGCCAA
GGCCCCGCCGAGCAATCGCCGCCTGCCCGAAGCGCAGCCGTTCGTGCCGACGCTGCAATTGGTGAGCGGCGCGATCAAGG
CCGACGACACAGAATTGAACGTCAACCCACGCGCCCGCAGCGCGGTGCTGCGGGTGGCTGAAAAGCTGGAATTGGGGATT
GGGGATTCGGGATTGGAGAGGCGCTCTGGGCGAATCCCCAATCCCCGATCCCCAATCCCGGCGTCTCAAGGAGACGCCCG
ATGA

Upstream 100 bases:

>100_bases
GAGCGAGCAGGCACATCGCGCACTGATCCAGCAGACATTGTCTGACGGGGATCTGGGCGATGAATTGCTCGATCTCAGGT
TGTGAGCCGGGGGTGCCCGG

Downstream 100 bases:

>100_bases
GCCGCCTGTTGCTCATCGTGCTGCTTGCCTGCAGCATCGCGTCGGCGATCGGTGTCGTGTACATGCGCCACATGCATCGC
AAGCTGTTCGTGCAGTTGTC

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MRGEAQPGHPVSQPPAAHVPVLYTQVLDGLQVTENGTYLDGTFGRGGHARGVLEHLGPGGRLLVMDKDPDAIAVAEQTFG
GDARVSIHRGSFAGLGQVVAAATVDGILLDLGVSSPQLDVAGRGFSFGKDGPLDMRMDPDSGQSAAQWLAQATDREIADV
LWAYGEERQSRRIARAIVARRAEQPLLRTAQLADLIASVMPRGDSKTHPATRSFQAIRIYINRELDDLETGLDAALAALK
PGGRLAVISFHSLEDRIVKQFMARYAKAPPSNRRLPEAQPFVPTLQLVSGAIKADDTELNVNPRARSAVLRVAEKLELGI
GDSGLERRSGRIPNPRSPIPASQGDAR

Sequences:

>Translated_347_residues
MRGEAQPGHPVSQPPAAHVPVLYTQVLDGLQVTENGTYLDGTFGRGGHARGVLEHLGPGGRLLVMDKDPDAIAVAEQTFG
GDARVSIHRGSFAGLGQVVAAATVDGILLDLGVSSPQLDVAGRGFSFGKDGPLDMRMDPDSGQSAAQWLAQATDREIADV
LWAYGEERQSRRIARAIVARRAEQPLLRTAQLADLIASVMPRGDSKTHPATRSFQAIRIYINRELDDLETGLDAALAALK
PGGRLAVISFHSLEDRIVKQFMARYAKAPPSNRRLPEAQPFVPTLQLVSGAIKADDTELNVNPRARSAVLRVAEKLELGI
GDSGLERRSGRIPNPRSPIPASQGDAR
>Mature_347_residues
MRGEAQPGHPVSQPPAAHVPVLYTQVLDGLQVTENGTYLDGTFGRGGHARGVLEHLGPGGRLLVMDKDPDAIAVAEQTFG
GDARVSIHRGSFAGLGQVVAAATVDGILLDLGVSSPQLDVAGRGFSFGKDGPLDMRMDPDSGQSAAQWLAQATDREIADV
LWAYGEERQSRRIARAIVARRAEQPLLRTAQLADLIASVMPRGDSKTHPATRSFQAIRIYINRELDDLETGLDAALAALK
PGGRLAVISFHSLEDRIVKQFMARYAKAPPSNRRLPEAQPFVPTLQLVSGAIKADDTELNVNPRARSAVLRVAEKLELGI
GDSGLERRSGRIPNPRSPIPASQGDAR

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=343, Percent_Identity=38.7755102040816, Blast_Score=194, Evalue=7e-50,
Organism=Homo sapiens, GI165377202, Length=193, Percent_Identity=39.3782383419689, Blast_Score=119, Evalue=3e-27,
Organism=Escherichia coli, GI1786270, Length=306, Percent_Identity=53.2679738562092, Blast_Score=306, Evalue=1e-84,
Organism=Drosophila melanogaster, GI62472493, Length=336, Percent_Identity=38.6904761904762, Blast_Score=185, Evalue=4e-47,
Organism=Drosophila melanogaster, GI28571637, Length=336, Percent_Identity=38.6904761904762, Blast_Score=185, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 37141; Mature: 37141

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGEAQPGHPVSQPPAAHVPVLYTQVLDGLQVTENGTYLDGTFGRGGHARGVLEHLGPGG
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEECCCCEECCCCCCCCCHHHHHHHCCCCC
RLLVMDKDPDAIAVAEQTFGGDARVSIHRGSFAGLGQVVAAATVDGILLDLGVSSPQLDV
EEEEEECCCCEEEEEHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHEEEECCCCCCCEEE
AGRGFSFGKDGPLDMRMDPDSGQSAAQWLAQATDREIADVLWAYGEERQSRRIARAIVAR
CCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
RAEQPLLRTAQLADLIASVMPRGDSKTHPATRSFQAIRIYINRELDDLETGLDAALAALK
HHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCC
PGGRLAVISFHSLEDRIVKQFMARYAKAPPSNRRLPEAQPFVPTLQLVSGAIKADDTELN
CCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEC
VNPRARSAVLRVAEKLELGIGDSGLERRSGRIPNPRSPIPASQGDAR
CCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRGEAQPGHPVSQPPAAHVPVLYTQVLDGLQVTENGTYLDGTFGRGGHARGVLEHLGPGG
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEECCCCEECCCCCCCCCHHHHHHHCCCCC
RLLVMDKDPDAIAVAEQTFGGDARVSIHRGSFAGLGQVVAAATVDGILLDLGVSSPQLDV
EEEEEECCCCEEEEEHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHEEEECCCCCCCEEE
AGRGFSFGKDGPLDMRMDPDSGQSAAQWLAQATDREIADVLWAYGEERQSRRIARAIVAR
CCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
RAEQPLLRTAQLADLIASVMPRGDSKTHPATRSFQAIRIYINRELDDLETGLDAALAALK
HHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCC
PGGRLAVISFHSLEDRIVKQFMARYAKAPPSNRRLPEAQPFVPTLQLVSGAIKADDTELN
CCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEC
VNPRARSAVLRVAEKLELGIGDSGLERRSGRIPNPRSPIPASQGDAR
CCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]