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The map label for this gene is mraY [H]

Identifier: 84625263

GI number: 84625263

Start: 4080297

End: 4081382

Strand: Reverse

Name: mraY [H]

Synonym: XOO_3606

Alternate gene names: 84625263

Gene position: 4081382-4080297 (Counterclockwise)

Preceding gene: 84625264

Following gene: 84625262

Centisome position: 82.62

GC content: 61.79

Gene sequence:

>1086_bases
ATGCTGCTTGAGCTGGCCCGTTGGCTGCAGCAACTGGAGAGCCTGTTCGGGCTGTTCAACTATTTGACCTTCCGCGGCAT
TTTGGCTGCGTTGACCGCGCTGTTCCTGTCGTTGTGGATGGGCCCTGCGGTGATCCGCAAGCTCGCCCAGTTCAAGGGCG
GCCAGCCGATCCGCCAGGACGGCCCGCAGACGCATTTTTCCAAGGCCGGCACGCCGACCATGGGCGGCTCGCTGATCCTG
CTCACCGTCACCTTGTCGGTGCTGCTGTGGGGCGACCTGCGTAATCGCTATGTGTGGTTGGTGCTGGCGGTGATGATCTG
CTTCGGTGCGATCGGCTGGTACGACGACTGGATCAAGATCGTGCGTCGCGACCCGAATGGGTTGAAATCGCGCTGGAAGT
ATCTGCTGCAGTCGATCTTCGGCCTGGCGGCCGGCTTGTTCCTGTACTACACCGCCGACGTCCCGGCGGCGATCACGTTT
TACATCCCGATGTTCAAGTCCATCGCGCTGCCGCTGGTCGGCGTGAGCTTCGTGGTGATCGCCTACTTCTGGATCGTGGG
TTTCTCCAATGCAGTGAACCTCACCGACGGCCTGGATGGTTTGGCCATCATGCCGACCGTGCTGGTGGCCTGCGCGCTGG
GGGTGTTCGCGTATGCGTCGGGCAACGTGGTGTTTGCCGAATACCTGAAAATCCCGCTGATTCCCGGCGCTGGCGAGCTG
ATCATCATCTGCTCGGCGATCGCCGGGGCAGGGTTGGGCTTTCTCTGGTTCAACACCTACCCTGCAATGGTGTTCATGGG
CGACATCGGCGCGCTGTCGCTGGGCGCGGTGCTCGGCACCATCGCGGTGATCGTGCGTCAGGAAATGGTGCTGGTGATCA
TGGGCGGCGTGTTCGTGATCGAAACGCTGTCGGTGATCATCCAGGTGGCCAGCTTCAAGCTGACCGGCAAGCGCGTGTTC
CGCATGGCGCCGATCCACCACCATTTCGAACTCAAGGGTTGGCCGGAGCCGCGCGTGATCGTGCGTTTCTGGATCATTTC
GGTGGTGCTGGTGCTGATCGGCCTTGCCACGTTGAAGGTGCGCTGA

Upstream 100 bases:

>100_bases
TCAGGTGCCGCCTCCATCACGATCCTGGTGAAGGGTTCGCGCGGCAGCGCGATGGACCGCGTCGTCACCGCGCTGCTCGC
ATCGGCGGAGGGCGCATCCC

Downstream 100 bases:

>100_bases
TGAACGACATGTCCCGCCAGGCCACACGACTGGACGCCATCGGCGGCCGCTACGATCCGTGGCTGCTCGGGGCCGCGGTC
ACGCTCGCCTCGCTGGGCGT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MLLELARWLQQLESLFGLFNYLTFRGILAALTALFLSLWMGPAVIRKLAQFKGGQPIRQDGPQTHFSKAGTPTMGGSLIL
LTVTLSVLLWGDLRNRYVWLVLAVMICFGAIGWYDDWIKIVRRDPNGLKSRWKYLLQSIFGLAAGLFLYYTADVPAAITF
YIPMFKSIALPLVGVSFVVIAYFWIVGFSNAVNLTDGLDGLAIMPTVLVACALGVFAYASGNVVFAEYLKIPLIPGAGEL
IIICSAIAGAGLGFLWFNTYPAMVFMGDIGALSLGAVLGTIAVIVRQEMVLVIMGGVFVIETLSVIIQVASFKLTGKRVF
RMAPIHHHFELKGWPEPRVIVRFWIISVVLVLIGLATLKVR

Sequences:

>Translated_361_residues
MLLELARWLQQLESLFGLFNYLTFRGILAALTALFLSLWMGPAVIRKLAQFKGGQPIRQDGPQTHFSKAGTPTMGGSLIL
LTVTLSVLLWGDLRNRYVWLVLAVMICFGAIGWYDDWIKIVRRDPNGLKSRWKYLLQSIFGLAAGLFLYYTADVPAAITF
YIPMFKSIALPLVGVSFVVIAYFWIVGFSNAVNLTDGLDGLAIMPTVLVACALGVFAYASGNVVFAEYLKIPLIPGAGEL
IIICSAIAGAGLGFLWFNTYPAMVFMGDIGALSLGAVLGTIAVIVRQEMVLVIMGGVFVIETLSVIIQVASFKLTGKRVF
RMAPIHHHFELKGWPEPRVIVRFWIISVVLVLIGLATLKVR
>Mature_361_residues
MLLELARWLQQLESLFGLFNYLTFRGILAALTALFLSLWMGPAVIRKLAQFKGGQPIRQDGPQTHFSKAGTPTMGGSLIL
LTVTLSVLLWGDLRNRYVWLVLAVMICFGAIGWYDDWIKIVRRDPNGLKSRWKYLLQSIFGLAAGLFLYYTADVPAAITF
YIPMFKSIALPLVGVSFVVIAYFWIVGFSNAVNLTDGLDGLAIMPTVLVACALGVFAYASGNVVFAEYLKIPLIPGAGEL
IIICSAIAGAGLGFLWFNTYPAMVFMGDIGALSLGAVLGTIAVIVRQEMVLVIMGGVFVIETLSVIIQVASFKLTGKRVF
RMAPIHHHFELKGWPEPRVIVRFWIISVVLVLIGLATLKVR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=361, Percent_Identity=60.9418282548476, Blast_Score=427, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 39665; Mature: 39665

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLELARWLQQLESLFGLFNYLTFRGILAALTALFLSLWMGPAVIRKLAQFKGGQPIRQD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCC
GPQTHFSKAGTPTMGGSLILLTVTLSVLLWGDLRNRYVWLVLAVMICFGAIGWYDDWIKI
CCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VRRDPNGLKSRWKYLLQSIFGLAAGLFLYYTADVPAAITFYIPMFKSIALPLVGVSFVVI
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AYFWIVGFSNAVNLTDGLDGLAIMPTVLVACALGVFAYASGNVVFAEYLKIPLIPGAGEL
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCCCCCCH
IIICSAIAGAGLGFLWFNTYPAMVFMGDIGALSLGAVLGTIAVIVRQEMVLVIMGGVFVI
HHHHHHHHHCCHHHHHHHHCCHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETLSVIIQVASFKLTGKRVFRMAPIHHHFELKGWPEPRVIVRFWIISVVLVLIGLATLKV
HHHHHHHHHHHHHCCHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
R
C
>Mature Secondary Structure
MLLELARWLQQLESLFGLFNYLTFRGILAALTALFLSLWMGPAVIRKLAQFKGGQPIRQD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCC
GPQTHFSKAGTPTMGGSLILLTVTLSVLLWGDLRNRYVWLVLAVMICFGAIGWYDDWIKI
CCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VRRDPNGLKSRWKYLLQSIFGLAAGLFLYYTADVPAAITFYIPMFKSIALPLVGVSFVVI
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AYFWIVGFSNAVNLTDGLDGLAIMPTVLVACALGVFAYASGNVVFAEYLKIPLIPGAGEL
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCCCCCCH
IIICSAIAGAGLGFLWFNTYPAMVFMGDIGALSLGAVLGTIAVIVRQEMVLVIMGGVFVI
HHHHHHHHHCCHHHHHHHHCCHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETLSVIIQVASFKLTGKRVFRMAPIHHHFELKGWPEPRVIVRFWIISVVLVLIGLATLKV
HHHHHHHHHHHHHCCHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]