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The map label for this gene is ftsW [H]

Identifier: 84625262

GI number: 84625262

Start: 4078924

End: 4080297

Strand: Reverse

Name: ftsW [H]

Synonym: XOO_3605

Alternate gene names: 84625262

Gene position: 4080297-4078924 (Counterclockwise)

Preceding gene: 84625263

Following gene: 84625261

Centisome position: 82.59

GC content: 64.85

Gene sequence:

>1374_bases
ATGAACGACATGTCCCGCCAGGCCACACGACTGGACGCCATCGGCGGCCGCTACGATCCGTGGCTGCTCGGGGCCGCGGT
CACGCTCGCCTCGCTGGGCGTGGTGATGGTGGCGTCCAGCTCGATCGAGCTGGAAGCCAGCCCGTTCTACTACCTGACCC
GCCACTTGCTGTTCCTGGGGGGCGGCATCGCGCTGGCGTTCTGGGCAATGCGCACCGAGCTCAAGACCATCGAACAGCAT
AACCAGATGCTGTTGCTGGCCTGCTTTGTGCTGCTCGTCGTGGTGTTCGTGCCTGGCCTGGGCAGCACCGTCAATGGCGC
CAAGCGCTGGATCAACCTGGGCGTGTCGCGGTTTCAGGTGGTCGAATCGGTGAAAGTGTTCTACATCATCTGGCTTGCGA
GCTATCTGGTGCGTTTCCGCGACGAGGTCAACGCGACCTGGCAGGCGATGCTCAAACCGGTGTTCGTGGTCGGCCTCTTG
GTCGGCCTGTTGCTGCTGCAGCCGGACTTCGGCTCCTCGATGCTGCTGCTGAGCGTGACCGCCTGCATGCTTGTGCTGGG
CGGTGCGCCGATCGGGCGCATCATCCTGCCGATCCTGCTGTTGCTGCCGGCATTGGTGGCATTGGTGATCTTCGAGCCGT
ACCGCATGCGGCGCGTGACCTCCTTCATGGACCCGTGGGTGGATCAGTTGGGCTCGGGCTACCAACTGTCCAACGCCCTG
ATGGCCATCGGTCGCGGTCAGTGGACCGGCGTAGGCCTGGGCGCCTCGGTACAGAAGCTCAACTATCTGCCCGAATCGCA
CACCGACTTCATCTTTTCGGTGATCGCCGAGGAACTGGGCTTTGTGGGTGTGTGCGGCGTGATCGGGTTGTACGCGCTGC
TGGTCGGTCGCGCCTTCTGGCTGGGCATGCGCTGCGTGGAAATGAAGCGGCATTTCTCCGGCTACATCGCCTTCGGCATC
GGCCTGTGGATCGCAATGCAGAGCTTCGTGTCGATCGGCGTCAACCTGGGCATCCTGCCGACCAAGGGGCTGACCCTGCC
GCTGATTTCGTCAGGCGGTTCATCGGTGCTGATGACCTGTCTTGCGATGGGTGTGCTGCTGCGGGTGTCCTACGAGGCCG
ATCGCGCCGAGCGCCTGCGCAGCAAGTTGTCTCCGCAGGGCGCGGCCATCTCGCCAGGTGAGCCAGCCGAGCCGGTGGTC
GATGCGGTACCGCCGGCCTACGCGCCTGCGCGCAAGCCGCAACGCGACACTGCCGCTGCGCCCGCACCTGCCGCCGCCCC
GGTTGCCGCCCATGTAGCACCGGCATCGGCCATCCTGCGCGGCACTAGCCGCATGCAACCGCGTGTGGAACCGACATTTG
GGAGGATTGCGTGA

Upstream 100 bases:

>100_bases
TCGAACTCAAGGGTTGGCCGGAGCCGCGCGTGATCGTGCGTTTCTGGATCATTTCGGTGGTGCTGGTGCTGATCGGCCTT
GCCACGTTGAAGGTGCGCTG

Downstream 100 bases:

>100_bases
GCGTTTATGCGCATCTCTCGCAAACGCCCGCACATCCATCTGCGCGGATTCAGCCGGTGATGATTCTGGCCGGCGGCACC
GGTGGGCATATTTTCCCGGG

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MNDMSRQATRLDAIGGRYDPWLLGAAVTLASLGVVMVASSSIELEASPFYYLTRHLLFLGGGIALAFWAMRTELKTIEQH
NQMLLLACFVLLVVVFVPGLGSTVNGAKRWINLGVSRFQVVESVKVFYIIWLASYLVRFRDEVNATWQAMLKPVFVVGLL
VGLLLLQPDFGSSMLLLSVTACMLVLGGAPIGRIILPILLLLPALVALVIFEPYRMRRVTSFMDPWVDQLGSGYQLSNAL
MAIGRGQWTGVGLGASVQKLNYLPESHTDFIFSVIAEELGFVGVCGVIGLYALLVGRAFWLGMRCVEMKRHFSGYIAFGI
GLWIAMQSFVSIGVNLGILPTKGLTLPLISSGGSSVLMTCLAMGVLLRVSYEADRAERLRSKLSPQGAAISPGEPAEPVV
DAVPPAYAPARKPQRDTAAAPAPAAAPVAAHVAPASAILRGTSRMQPRVEPTFGRIA

Sequences:

>Translated_457_residues
MNDMSRQATRLDAIGGRYDPWLLGAAVTLASLGVVMVASSSIELEASPFYYLTRHLLFLGGGIALAFWAMRTELKTIEQH
NQMLLLACFVLLVVVFVPGLGSTVNGAKRWINLGVSRFQVVESVKVFYIIWLASYLVRFRDEVNATWQAMLKPVFVVGLL
VGLLLLQPDFGSSMLLLSVTACMLVLGGAPIGRIILPILLLLPALVALVIFEPYRMRRVTSFMDPWVDQLGSGYQLSNAL
MAIGRGQWTGVGLGASVQKLNYLPESHTDFIFSVIAEELGFVGVCGVIGLYALLVGRAFWLGMRCVEMKRHFSGYIAFGI
GLWIAMQSFVSIGVNLGILPTKGLTLPLISSGGSSVLMTCLAMGVLLRVSYEADRAERLRSKLSPQGAAISPGEPAEPVV
DAVPPAYAPARKPQRDTAAAPAPAAAPVAAHVAPASAILRGTSRMQPRVEPTFGRIA
>Mature_457_residues
MNDMSRQATRLDAIGGRYDPWLLGAAVTLASLGVVMVASSSIELEASPFYYLTRHLLFLGGGIALAFWAMRTELKTIEQH
NQMLLLACFVLLVVVFVPGLGSTVNGAKRWINLGVSRFQVVESVKVFYIIWLASYLVRFRDEVNATWQAMLKPVFVVGLL
VGLLLLQPDFGSSMLLLSVTACMLVLGGAPIGRIILPILLLLPALVALVIFEPYRMRRVTSFMDPWVDQLGSGYQLSNAL
MAIGRGQWTGVGLGASVQKLNYLPESHTDFIFSVIAEELGFVGVCGVIGLYALLVGRAFWLGMRCVEMKRHFSGYIAFGI
GLWIAMQSFVSIGVNLGILPTKGLTLPLISSGGSSVLMTCLAMGVLLRVSYEADRAERLRSKLSPQGAAISPGEPAEPVV
DAVPPAYAPARKPQRDTAAAPAPAAAPVAAHVAPASAILRGTSRMQPRVEPTFGRIA

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=365, Percent_Identity=44.3835616438356, Blast_Score=281, Evalue=9e-77,
Organism=Escherichia coli, GI1786853, Length=291, Percent_Identity=34.020618556701, Blast_Score=119, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 49203; Mature: 49203

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDMSRQATRLDAIGGRYDPWLLGAAVTLASLGVVMVASSSIELEASPFYYLTRHLLFLG
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEECCCCEECCCCHHHHHHHHHHHC
GGIALAFWAMRTELKTIEQHNQMLLLACFVLLVVVFVPGLGSTVNGAKRWINLGVSRFQV
CHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VESVKVFYIIWLASYLVRFRDEVNATWQAMLKPVFVVGLLVGLLLLQPDFGSSMLLLSVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ACMLVLGGAPIGRIILPILLLLPALVALVIFEPYRMRRVTSFMDPWVDQLGSGYQLSNAL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCHHHHH
MAIGRGQWTGVGLGASVQKLNYLPESHTDFIFSVIAEELGFVGVCGVIGLYALLVGRAFW
HHHCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
LGMRCVEMKRHFSGYIAFGIGLWIAMQSFVSIGVNLGILPTKGLTLPLISSGGSSVLMTC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEECCCCHHHHHHH
LAMGVLLRVSYEADRAERLRSKLSPQGAAISPGEPAEPVVDAVPPAYAPARKPQRDTAAA
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCC
PAPAAAPVAAHVAPASAILRGTSRMQPRVEPTFGRIA
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNDMSRQATRLDAIGGRYDPWLLGAAVTLASLGVVMVASSSIELEASPFYYLTRHLLFLG
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEECCCCEECCCCHHHHHHHHHHHC
GGIALAFWAMRTELKTIEQHNQMLLLACFVLLVVVFVPGLGSTVNGAKRWINLGVSRFQV
CHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VESVKVFYIIWLASYLVRFRDEVNATWQAMLKPVFVVGLLVGLLLLQPDFGSSMLLLSVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ACMLVLGGAPIGRIILPILLLLPALVALVIFEPYRMRRVTSFMDPWVDQLGSGYQLSNAL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCHHHHH
MAIGRGQWTGVGLGASVQKLNYLPESHTDFIFSVIAEELGFVGVCGVIGLYALLVGRAFW
HHHCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
LGMRCVEMKRHFSGYIAFGIGLWIAMQSFVSIGVNLGILPTKGLTLPLISSGGSSVLMTC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEECCCCHHHHHHH
LAMGVLLRVSYEADRAERLRSKLSPQGAAISPGEPAEPVVDAVPPAYAPARKPQRDTAAA
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCC
PAPAAAPVAAHVAPASAILRGTSRMQPRVEPTFGRIA
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]