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The map label for this gene is moaC [H]

Identifier: 84622618

GI number: 84622618

Start: 1051619

End: 1052116

Strand: Direct

Name: moaC [H]

Synonym: XOO_0961

Alternate gene names: 84622618

Gene position: 1051619-1052116 (Clockwise)

Preceding gene: 84622617

Following gene: 84622619

Centisome position: 21.29

GC content: 64.26

Gene sequence:

>498_bases
ATGCCTGCAAAATCCCGTTCCGCACGCCTGACACACCTCGACGATGCCGGGCTTCCCACGATGGTGGATGTCTCGGGCAA
GGCGATCACCGCCCGTAGCGCGACTGCAGAAAGCCGCGTGCGCTTTCCGGCAGCCGTGGCCGCACAGCTGCGCGCCAACG
GCTTGCGTAGCGCCAAGGGCGGCATCGTGGAGACGGCGGTGATTGCCGGCACCATGGCGGTCAAGCGCACGCACGAATTG
ATTCCGTTCTGCCACCCATTGCCGATCGATGCCTGCCGTTTCGAGATCGACTGGGCGGGCGAGCAGGTGCTGGACATCCG
TTGCACGGTGCGTTGCGTGCATCGTACCGGCGTGGAAATGGAGGCGCTTACCGGTGCCAGCGTGGCTGCGCTGACGGTCT
ATGACATGTGCAAGGCGTTGTCGCACAGCATGAGCATTGGTCCGACCAGATTGGTGTCCAAGCGCGGCGGCAAGCGCGAT
ATCGGAGCGGCGCAATGA

Upstream 100 bases:

>100_bases
GTGGCATAGGAACGCTGATGGATGGCAGCTGCTGTTTCATCAAGGCACCCTGTTCACCGAGAATGCCGCATCCTGATTGC
CTGTCTTCGCGTTGCTTCCC

Downstream 100 bases:

>100_bases
CTGCGACAGTGACGGTGCTGTATTTCGCCAGCCTGCGCGAGGCAGTAGGCATGGCCGACGAGCGCGTGCAGTCCGATGCA
CCGAGCTTGCGTGGCCTGTA

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MPAKSRSARLTHLDDAGLPTMVDVSGKAITARSATAESRVRFPAAVAAQLRANGLRSAKGGIVETAVIAGTMAVKRTHEL
IPFCHPLPIDACRFEIDWAGEQVLDIRCTVRCVHRTGVEMEALTGASVAALTVYDMCKALSHSMSIGPTRLVSKRGGKRD
IGAAQ

Sequences:

>Translated_165_residues
MPAKSRSARLTHLDDAGLPTMVDVSGKAITARSATAESRVRFPAAVAAQLRANGLRSAKGGIVETAVIAGTMAVKRTHEL
IPFCHPLPIDACRFEIDWAGEQVLDIRCTVRCVHRTGVEMEALTGASVAALTVYDMCKALSHSMSIGPTRLVSKRGGKRD
IGAAQ
>Mature_164_residues
PAKSRSARLTHLDDAGLPTMVDVSGKAITARSATAESRVRFPAAVAAQLRANGLRSAKGGIVETAVIAGTMAVKRTHELI
PFCHPLPIDACRFEIDWAGEQVLDIRCTVRCVHRTGVEMEALTGASVAALTVYDMCKALSHSMSIGPTRLVSKRGGKRDI
GAAQ

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=154, Percent_Identity=48.7012987012987, Blast_Score=123, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI32566331, Length=151, Percent_Identity=41.0596026490066, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI28574490, Length=155, Percent_Identity=47.741935483871, Blast_Score=129, Evalue=8e-31,
Organism=Drosophila melanogaster, GI28574492, Length=142, Percent_Identity=50, Blast_Score=122, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17495; Mature: 17363

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAKSRSARLTHLDDAGLPTMVDVSGKAITARSATAESRVRFPAAVAAQLRANGLRSAKG
CCCCCCCCEEEECCCCCCCEEEECCCCEEEECCCCCHHHHCCHHHHHHHHHHCCCCCCCC
GIVETAVIAGTMAVKRTHELIPFCHPLPIDACRFEIDWAGEQVLDIRCTVRCVHRTGVEM
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEHHHHEEEEHHCCCEE
EALTGASVAALTVYDMCKALSHSMSIGPTRLVSKRGGKRDIGAAQ
EHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
PAKSRSARLTHLDDAGLPTMVDVSGKAITARSATAESRVRFPAAVAAQLRANGLRSAKG
CCCCCCCEEEECCCCCCCEEEECCCCEEEECCCCCHHHHCCHHHHHHHHHHCCCCCCCC
GIVETAVIAGTMAVKRTHELIPFCHPLPIDACRFEIDWAGEQVLDIRCTVRCVHRTGVEM
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEHHHHEEEEHHCCCEE
EALTGASVAALTVYDMCKALSHSMSIGPTRLVSKRGGKRDIGAAQ
EHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]