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The map label for this gene is yjcE [H]

Identifier: 84622269

GI number: 84622269

Start: 664801

End: 666543

Strand: Direct

Name: yjcE [H]

Synonym: XOO_0612

Alternate gene names: 84622269

Gene position: 664801-666543 (Clockwise)

Preceding gene: 84622268

Following gene: 84622270

Centisome position: 13.46

GC content: 64.95

Gene sequence:

>1743_bases
GTGGTTTCATCGCCGGTTGCAACCCGGTATGGTCCCGTAAGTGCGTTGTTGTGCGTCGCAATATGCGATGCCGCACGTGC
GGCCGCTCTTTCATTCCGGGTTTTTATGCATTCGATCGATGTCGTCCTCGCCATGTTGCTGGCGGTCGCGGCCAGCGGTT
ATCTCATCCGCATCCTGCCGTTCTCGCTACCGTTGCCGTTGGTCCAGATTGCGCTGGGCGCGGTGGTCTCCGGCGTGTTC
GATGCGGGGCACGAACTGGAGCCGGAGCTGTTCTTCCTGTTGTTCCTGCCGCCACTGCTGTTTCTGGATGGCTGGCGCAT
TCCCAAACAAGGCCTGTTCCGCGACAAGGCGGCAATCCTGGAACTGGCGTTGGGGCTGGTCATCTTCACCGTGATTGGTG
CCGGCGTCTTCATCCATTGGCTGATACCGGCGATGCCGCTGGCCGTGGCGTTCGCGCTGGCGGCGATCATTTCGCCGACC
GACCCGGTGGCGGTGTCGTCGATCGCCTCCAAGGTGCCGATTCCCAAGCGCCTGATGCACATCCTGGAAGGCGAGTCGCT
GCTCAACGACGCCTCGGGCCTGGTGTGTTTCCAATTCGCGGTGGCGGCCGTGCTCACTGGCACCTTCTCGGTCACGGCCG
CTTCGCTGACCTTCCTGTGGGTGGCGCTGGCTGGTCTGGCCTTGGGCGTGGCGACGACCTTCGGGTTGAGCCGCATCCAG
GCCTGGATCTGGCGGCACTTCGGCGAGGAGCCCGGTTCGGCGATCCTGGTCAACCTGCTCACCCCGTTTGCAGCCTATCT
GCTGGCCGAAGCCTTCCATGCATCGGGCATCCTGGCCGCGGTGGCCGCCGGCATCACCATGAGTTACGTGGAAATGGCCG
GCAACGCGCCGGGCAACATGCGCCTGCAGCGTTCGGCGGTGTGGGACACGGTGCAGTTCACCTTCAACGGCATCATCTTC
GTGCTGCTGGGCGAGCAGTTGCCGGGCATTCTGGACGGCGCGGTGCGCAGCGTGCAGGAGGCCGGGCACCTCAATCCGTG
GTGGCTGGCGGTGTACGTGGCCACCATCAGCGCCAGCCTGATGGCGTTGCGCTTCGTCTGGGTGTTCCTGTCGCTGCGCT
GGAATATCTTCAAGGCGCAGCGACGCGGCGAGGCGCATGTCAGCCCGCCGTGGCGGATCGTGGTGGCGGTGTCGCTGGCC
GGCGTGCGCGGCGCGATCACCCTGGCTGGCGTGCTCACGCTGCCCTTGATGCTGGAGGACGGCTCGCCATTCCCGGCCCG
CCAGTTGGCGATCTTCCTGGCGGCCTCGGTCATTCTGGTGTCGTTGCTGGTTGCCAGCGTTGCGTTGCCGCGGTTGTTGC
GCGGGCTGGAGCTTCCCGAAGAAGAAGACGAGCAGCTCAAGGAAGACCTGGCCGCGAAAGCCGCCTCGCAGGCAGCGCTG
GATGCAGTGGAAAAACTGCGGCAGCGGCTGGTGGATGGCAGCAAACATGCCGAGCGCTACAACGCGGCGGCCAACCAGGT
CAGTCAGCGCTATCAGCGCAAGCTCGGCTCGGTGGACATGGCCGAGACCGATCCGGAAGAGGCGGTGGCCTACGAAAAGG
CGCTGCGTCAGTTCCGGCATGCGGCGTTGGTGGCCGAGCGCAATGAGTTGTTCAAGCTGGCCCGACGCCGCGAGATTTCC
GACGAGTTGTCGCGGCGGCTGGTGCGCAATCTGGATCTGATCGAGTCGCGCAAGCGCGCTTGA

Upstream 100 bases:

>100_bases
CGGCAGACACCATGTCGGACCGACAGACACACGCCACAGTGCGTAGCACGACACCATGGTGGCGATCACTCCGCAGGACC
ACTCAGGGCCATGCGGTGCG

Downstream 100 bases:

>100_bases
GCGCGTGGGAATGGGGATTGGGGAATCGCAAGAGCCACGGCGGTCGTGAGGTCGTCGTTGTGAAGGAGCGCGCTTGCGCG
CGATAGCACTCCGTACTGAT

Product: Na+:H+ antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 580; Mature: 580

Protein sequence:

>580_residues
MVSSPVATRYGPVSALLCVAICDAARAAALSFRVFMHSIDVVLAMLLAVAASGYLIRILPFSLPLPLVQIALGAVVSGVF
DAGHELEPELFFLLFLPPLLFLDGWRIPKQGLFRDKAAILELALGLVIFTVIGAGVFIHWLIPAMPLAVAFALAAIISPT
DPVAVSSIASKVPIPKRLMHILEGESLLNDASGLVCFQFAVAAVLTGTFSVTAASLTFLWVALAGLALGVATTFGLSRIQ
AWIWRHFGEEPGSAILVNLLTPFAAYLLAEAFHASGILAAVAAGITMSYVEMAGNAPGNMRLQRSAVWDTVQFTFNGIIF
VLLGEQLPGILDGAVRSVQEAGHLNPWWLAVYVATISASLMALRFVWVFLSLRWNIFKAQRRGEAHVSPPWRIVVAVSLA
GVRGAITLAGVLTLPLMLEDGSPFPARQLAIFLAASVILVSLLVASVALPRLLRGLELPEEEDEQLKEDLAAKAASQAAL
DAVEKLRQRLVDGSKHAERYNAAANQVSQRYQRKLGSVDMAETDPEEAVAYEKALRQFRHAALVAERNELFKLARRREIS
DELSRRLVRNLDLIESRKRA

Sequences:

>Translated_580_residues
MVSSPVATRYGPVSALLCVAICDAARAAALSFRVFMHSIDVVLAMLLAVAASGYLIRILPFSLPLPLVQIALGAVVSGVF
DAGHELEPELFFLLFLPPLLFLDGWRIPKQGLFRDKAAILELALGLVIFTVIGAGVFIHWLIPAMPLAVAFALAAIISPT
DPVAVSSIASKVPIPKRLMHILEGESLLNDASGLVCFQFAVAAVLTGTFSVTAASLTFLWVALAGLALGVATTFGLSRIQ
AWIWRHFGEEPGSAILVNLLTPFAAYLLAEAFHASGILAAVAAGITMSYVEMAGNAPGNMRLQRSAVWDTVQFTFNGIIF
VLLGEQLPGILDGAVRSVQEAGHLNPWWLAVYVATISASLMALRFVWVFLSLRWNIFKAQRRGEAHVSPPWRIVVAVSLA
GVRGAITLAGVLTLPLMLEDGSPFPARQLAIFLAASVILVSLLVASVALPRLLRGLELPEEEDEQLKEDLAAKAASQAAL
DAVEKLRQRLVDGSKHAERYNAAANQVSQRYQRKLGSVDMAETDPEEAVAYEKALRQFRHAALVAERNELFKLARRREIS
DELSRRLVRNLDLIESRKRA
>Mature_580_residues
MVSSPVATRYGPVSALLCVAICDAARAAALSFRVFMHSIDVVLAMLLAVAASGYLIRILPFSLPLPLVQIALGAVVSGVF
DAGHELEPELFFLLFLPPLLFLDGWRIPKQGLFRDKAAILELALGLVIFTVIGAGVFIHWLIPAMPLAVAFALAAIISPT
DPVAVSSIASKVPIPKRLMHILEGESLLNDASGLVCFQFAVAAVLTGTFSVTAASLTFLWVALAGLALGVATTFGLSRIQ
AWIWRHFGEEPGSAILVNLLTPFAAYLLAEAFHASGILAAVAAGITMSYVEMAGNAPGNMRLQRSAVWDTVQFTFNGIIF
VLLGEQLPGILDGAVRSVQEAGHLNPWWLAVYVATISASLMALRFVWVFLSLRWNIFKAQRRGEAHVSPPWRIVVAVSLA
GVRGAITLAGVLTLPLMLEDGSPFPARQLAIFLAASVILVSLLVASVALPRLLRGLELPEEEDEQLKEDLAAKAASQAAL
DAVEKLRQRLVDGSKHAERYNAAANQVSQRYQRKLGSVDMAETDPEEAVAYEKALRQFRHAALVAERNELFKLARRREIS
DELSRRLVRNLDLIESRKRA

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI15529998, Length=575, Percent_Identity=23.8260869565217, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI148727259, Length=506, Percent_Identity=22.7272727272727, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI41872703, Length=483, Percent_Identity=24.8447204968944, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI4759144, Length=257, Percent_Identity=31.1284046692607, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI27777632, Length=506, Percent_Identity=25.4940711462451, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI194239733, Length=453, Percent_Identity=25.1655629139073, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI27734935, Length=415, Percent_Identity=22.1686746987952, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI110227626, Length=258, Percent_Identity=27.1317829457364, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI294997330, Length=258, Percent_Identity=27.1317829457364, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI5454070, Length=258, Percent_Identity=27.1317829457364, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI14211919, Length=414, Percent_Identity=23.1884057971014, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1790501, Length=545, Percent_Identity=42.5688073394495, Blast_Score=377, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI71987559, Length=432, Percent_Identity=24.7685185185185, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71987545, Length=432, Percent_Identity=24.7685185185185, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25150332, Length=474, Percent_Identity=23.4177215189873, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71993590, Length=404, Percent_Identity=26.980198019802, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71993582, Length=404, Percent_Identity=26.980198019802, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71999819, Length=553, Percent_Identity=21.1573236889693, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71980847, Length=531, Percent_Identity=22.7871939736347, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71987535, Length=551, Percent_Identity=22.3230490018149, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25147678, Length=404, Percent_Identity=23.7623762376238, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71999821, Length=494, Percent_Identity=21.2550607287449, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71999817, Length=525, Percent_Identity=20.952380952381, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71987537, Length=523, Percent_Identity=22.1797323135755, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71992107, Length=339, Percent_Identity=23.3038348082596, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71992101, Length=339, Percent_Identity=23.3038348082596, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320663, Length=265, Percent_Identity=25.6603773584906, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221510738, Length=514, Percent_Identity=23.3463035019455, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI221510734, Length=437, Percent_Identity=24.0274599542334, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281360447, Length=539, Percent_Identity=24.30426716141, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI221473222, Length=434, Percent_Identity=24.6543778801843, Blast_Score=86, Evalue=9e-17,
Organism=Drosophila melanogaster, GI281364513, Length=439, Percent_Identity=24.6013667425968, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI221510736, Length=430, Percent_Identity=26.2790697674419, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI221510732, Length=430, Percent_Identity=25.8139534883721, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24585580, Length=430, Percent_Identity=25.8139534883721, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24585578, Length=430, Percent_Identity=25.8139534883721, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221510740, Length=430, Percent_Identity=25.8139534883721, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221473212, Length=407, Percent_Identity=25.0614250614251, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI221473215, Length=407, Percent_Identity=25.0614250614251, Blast_Score=83, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 62753; Mature: 62753

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSSPVATRYGPVSALLCVAICDAARAAALSFRVFMHSIDVVLAMLLAVAASGYLIRILP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
FSLPLPLVQIALGAVVSGVFDAGHELEPELFFLLFLPPLLFLDGWRIPKQGLFRDKAAIL
CCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ELALGLVIFTVIGAGVFIHWLIPAMPLAVAFALAAIISPTDPVAVSSIASKVPIPKRLMH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHH
ILEGESLLNDASGLVCFQFAVAAVLTGTFSVTAASLTFLWVALAGLALGVATTFGLSRIQ
HHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWIWRHFGEEPGSAILVNLLTPFAAYLLAEAFHASGILAAVAAGITMSYVEMAGNAPGNM
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RLQRSAVWDTVQFTFNGIIFVLLGEQLPGILDGAVRSVQEAGHLNPWWLAVYVATISASL
EEEHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
MALRFVWVFLSLRWNIFKAQRRGEAHVSPPWRIVVAVSLAGVRGAITLAGVLTLPLMLED
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHCHHHHHHHHHHHHHHHEEEC
GSPFPARQLAIFLAASVILVSLLVASVALPRLLRGLELPEEEDEQLKEDLAAKAASQAAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
DAVEKLRQRLVDGSKHAERYNAAANQVSQRYQRKLGSVDMAETDPEEAVAYEKALRQFRH
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
AALVAERNELFKLARRREISDELSRRLVRNLDLIESRKRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVSSPVATRYGPVSALLCVAICDAARAAALSFRVFMHSIDVVLAMLLAVAASGYLIRILP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
FSLPLPLVQIALGAVVSGVFDAGHELEPELFFLLFLPPLLFLDGWRIPKQGLFRDKAAIL
CCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ELALGLVIFTVIGAGVFIHWLIPAMPLAVAFALAAIISPTDPVAVSSIASKVPIPKRLMH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHH
ILEGESLLNDASGLVCFQFAVAAVLTGTFSVTAASLTFLWVALAGLALGVATTFGLSRIQ
HHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWIWRHFGEEPGSAILVNLLTPFAAYLLAEAFHASGILAAVAAGITMSYVEMAGNAPGNM
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RLQRSAVWDTVQFTFNGIIFVLLGEQLPGILDGAVRSVQEAGHLNPWWLAVYVATISASL
EEEHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
MALRFVWVFLSLRWNIFKAQRRGEAHVSPPWRIVVAVSLAGVRGAITLAGVLTLPLMLED
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHCHHHHHHHHHHHHHHHEEEC
GSPFPARQLAIFLAASVILVSLLVASVALPRLLRGLELPEEEDEQLKEDLAAKAASQAAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
DAVEKLRQRLVDGSKHAERYNAAANQVSQRYQRKLGSVDMAETDPEEAVAYEKALRQFRH
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
AALVAERNELFKLARRREISDELSRRLVRNLDLIESRKRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]