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The map label for this gene is lytS [H]

Identifier: 84622252

GI number: 84622252

Start: 645991

End: 647322

Strand: Direct

Name: lytS [H]

Synonym: XOO_0595

Alternate gene names: 84622252

Gene position: 645991-647322 (Clockwise)

Preceding gene: 84622250

Following gene: 84622253

Centisome position: 13.08

GC content: 66.14

Gene sequence:

>1332_bases
ATGCTCGCCGCGTCCCATCCCAACGCGCTGCCATCCGTGTCCGCCAGCGTGTTCCTGATCGTGCGTATCGTGTTCGTCTG
GGCCGCCGCGTTGGTGGTGGCAGGGCTCATGTGGGCGCAGCTGTTCGGCGTCATCGGCCCGATCTTCGCATTGGCCTGCA
TGGTCCTTCTGACGCTGGCCTTGATGAGTTCGATCACCCATGTGCGGCGCGTTCGCCTGATCGCCGATCGGCTGGATCAC
ACCACCTTGTCCACCCGTCAGCGCCGCCAGATCGAAGTGCCGCTGGATGTGCAGGCAAGCTTTGCGGTGACGGAAGAGGC
GGTGCGTGCGCTGCCACGTGTGCAGGACATCGAGTGTGCGCCGGGCAGCCTGCTGATCCGTGCCAAGGTGCGCCGCATCG
ACCCGTATGAAGGACGCCAGCTGTCGCGCTGGAATCTGTTCGCGCGCTTTGCCATTACCCACAACCAGATCCTGGCGACG
ATCGCGCCGGGGCAGGGCACCAGTAGCGTCACCGTGCTGTGCGAGCCCGATGCTGGCGCCTGGGTGGATCTGTTTGCGGT
GGACGAAGGCAGCAATTACGAAAACGCCGAGGCGATCAATCGCGCGGTGGTGCGCCGGGTCGGCGAGCAGCGTCGCGACG
CACAGGCCGCCGCCGAGCAATCGGTGATGGAAAAGGAACTGGCCGTGGCGCGTCTGAATCTGCTGCATGCGCAGGTCGAA
CCGCACTTTCTCTACAACACGCTGGCGAGCGCGCACGTGCTGGCGCGCACCGATCCGCCGCGTGCGGAGATCATGATCGG
CGATCTGATCCAGTACCTGCGCCGCTCGCTGCCCAGCGCCGACGGTGCCATCGCCACCCTGGGCGAAGAACTCGAACGCA
CCCAGGCGTACCTGGAGATCCTGCGCATCCGCATGGGCACGCGGCTCGCCTTGCAGGTGGAAGTGCCGTACGCACTGCGT
GCGCTTCCGCTGCCGTCGATGATGTTGCAGACGCTGGTGGAAAACGCGATCACGCACGGGCTGGAAGCCAAGCCAGGCGG
CGGCACCGTGTGGATTCTGGCGCGTCGCCACGACGACCATGCCACGCTCACCGTGGCCGACGATGGCCAGGGCTTGAACA
CGCACAGCCAGGGCACCGGCATCGGCCTGAAGAACCTGCGCGAGCGGCTGAAGTTGATCTATGCCGACAAGGCGACCTTT
GCCATCGTGTCCACTTTCCCCAGCGGGGTGGCGGCCACCACCAGCCTGCCATTGCCGGCGCAGCTGGTTGCTGCACCCTC
ACCGCCGCCGATGCCTACCGTGGCTGCGCACGCCCCGCAGGTGCAGGCATGA

Upstream 100 bases:

>100_bases
CTGCGCCGCAGCGCCACGGTTTGGCACCGCAATCCCGGCGCGTGATGCCGCGCTGGCGGCCATTCGTCGCCCGGGGCTTC
CGTCGTGGCGCGCGCCGGCT

Downstream 100 bases:

>100_bases
GCGCACTGCGTGCCGTGGTTGCAGAAGACGAAGCGTTGCTGCGGCAGTCGTTGCTGACCCTGCTGGCCGAGGTGTGCCCG
CAGCTGCAGATCGTCGGCGA

Product: hypothetical protein

Products: NA

Alternate protein names: Autolysin sensor kinase [H]

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MLAASHPNALPSVSASVFLIVRIVFVWAAALVVAGLMWAQLFGVIGPIFALACMVLLTLALMSSITHVRRVRLIADRLDH
TTLSTRQRRQIEVPLDVQASFAVTEEAVRALPRVQDIECAPGSLLIRAKVRRIDPYEGRQLSRWNLFARFAITHNQILAT
IAPGQGTSSVTVLCEPDAGAWVDLFAVDEGSNYENAEAINRAVVRRVGEQRRDAQAAAEQSVMEKELAVARLNLLHAQVE
PHFLYNTLASAHVLARTDPPRAEIMIGDLIQYLRRSLPSADGAIATLGEELERTQAYLEILRIRMGTRLALQVEVPYALR
ALPLPSMMLQTLVENAITHGLEAKPGGGTVWILARRHDDHATLTVADDGQGLNTHSQGTGIGLKNLRERLKLIYADKATF
AIVSTFPSGVAATTSLPLPAQLVAAPSPPPMPTVAAHAPQVQA

Sequences:

>Translated_443_residues
MLAASHPNALPSVSASVFLIVRIVFVWAAALVVAGLMWAQLFGVIGPIFALACMVLLTLALMSSITHVRRVRLIADRLDH
TTLSTRQRRQIEVPLDVQASFAVTEEAVRALPRVQDIECAPGSLLIRAKVRRIDPYEGRQLSRWNLFARFAITHNQILAT
IAPGQGTSSVTVLCEPDAGAWVDLFAVDEGSNYENAEAINRAVVRRVGEQRRDAQAAAEQSVMEKELAVARLNLLHAQVE
PHFLYNTLASAHVLARTDPPRAEIMIGDLIQYLRRSLPSADGAIATLGEELERTQAYLEILRIRMGTRLALQVEVPYALR
ALPLPSMMLQTLVENAITHGLEAKPGGGTVWILARRHDDHATLTVADDGQGLNTHSQGTGIGLKNLRERLKLIYADKATF
AIVSTFPSGVAATTSLPLPAQLVAAPSPPPMPTVAAHAPQVQA
>Mature_443_residues
MLAASHPNALPSVSASVFLIVRIVFVWAAALVVAGLMWAQLFGVIGPIFALACMVLLTLALMSSITHVRRVRLIADRLDH
TTLSTRQRRQIEVPLDVQASFAVTEEAVRALPRVQDIECAPGSLLIRAKVRRIDPYEGRQLSRWNLFARFAITHNQILAT
IAPGQGTSSVTVLCEPDAGAWVDLFAVDEGSNYENAEAINRAVVRRVGEQRRDAQAAAEQSVMEKELAVARLNLLHAQVE
PHFLYNTLASAHVLARTDPPRAEIMIGDLIQYLRRSLPSADGAIATLGEELERTQAYLEILRIRMGTRLALQVEVPYALR
ALPLPSMMLQTLVENAITHGLEAKPGGGTVWILARRHDDHATLTVADDGQGLNTHSQGTGIGLKNLRERLKLIYADKATF
AIVSTFPSGVAATTSLPLPAQLVAAPSPPPMPTVAAHAPQVQA

Specific function: Member of the two-component regulatory system lytR/lytS that probably regulates genes involved in cell wall metabolism [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=231, Percent_Identity=32.034632034632, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788723, Length=176, Percent_Identity=30.1136363636364, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48081; Mature: 48081

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAASHPNALPSVSASVFLIVRIVFVWAAALVVAGLMWAQLFGVIGPIFALACMVLLTLA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMSSITHVRRVRLIADRLDHTTLSTRQRRQIEVPLDVQASFAVTEEAVRALPRVQDIECA
HHHHHHHHHHHHHHHHHHCCHHHCCHHHCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCC
PGSLLIRAKVRRIDPYEGRQLSRWNLFARFAITHNQILATIAPGQGTSSVTVLCEPDAGA
CCCEEEEEHHHCCCCCCCCCCHHHHHEEEEEEECCEEEEEECCCCCCCEEEEEECCCCCC
WVDLFAVDEGSNYENAEAINRAVVRRVGEQRRDAQAAAEQSVMEKELAVARLNLLHAQVE
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PHFLYNTLASAHVLARTDPPRAEIMIGDLIQYLRRSLPSADGAIATLGEELERTQAYLEI
CHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LRIRMGTRLALQVEVPYALRALPLPSMMLQTLVENAITHGLEAKPGGGTVWILARRHDDH
HHHHCCCEEEEEEECCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCC
ATLTVADDGQGLNTHSQGTGIGLKNLRERLKLIYADKATFAIVSTFPSGVAATTSLPLPA
EEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCEECCCCCCCH
QLVAAPSPPPMPTVAAHAPQVQA
HHEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLAASHPNALPSVSASVFLIVRIVFVWAAALVVAGLMWAQLFGVIGPIFALACMVLLTLA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMSSITHVRRVRLIADRLDHTTLSTRQRRQIEVPLDVQASFAVTEEAVRALPRVQDIECA
HHHHHHHHHHHHHHHHHHCCHHHCCHHHCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCC
PGSLLIRAKVRRIDPYEGRQLSRWNLFARFAITHNQILATIAPGQGTSSVTVLCEPDAGA
CCCEEEEEHHHCCCCCCCCCCHHHHHEEEEEEECCEEEEEECCCCCCCEEEEEECCCCCC
WVDLFAVDEGSNYENAEAINRAVVRRVGEQRRDAQAAAEQSVMEKELAVARLNLLHAQVE
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PHFLYNTLASAHVLARTDPPRAEIMIGDLIQYLRRSLPSADGAIATLGEELERTQAYLEI
CHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LRIRMGTRLALQVEVPYALRALPLPSMMLQTLVENAITHGLEAKPGGGTVWILARRHDDH
HHHHCCCEEEEEEECCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCC
ATLTVADDGQGLNTHSQGTGIGLKNLRERLKLIYADKATFAIVSTFPSGVAATTSLPLPA
EEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCEECCCCCCCH
QLVAAPSPPPMPTVAAHAPQVQA
HHEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA