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The map label for this gene is coaX [H]

Identifier: 84622048

GI number: 84622048

Start: 424988

End: 425716

Strand: Direct

Name: coaX [H]

Synonym: XOO_0391

Alternate gene names: 84622048

Gene position: 424988-425716 (Clockwise)

Preceding gene: 84622047

Following gene: 84622049

Centisome position: 8.6

GC content: 71.33

Gene sequence:

>729_bases
ATGAGCGAGTGGTTGTTCGACCTGGGAAATTCGCGGTTCAAGTACGCGCCGCTGCACGGCAACCGTGCCGGCCAAGTGCA
GGCATGGGCACACGGCGCCGAGGCCATGGATGCGGCCGCGCTGGCGGCGCTGCCGTCCGGGCAGATCGCGCACGTTGCCA
GCGTGGCCGCACCGGCATTGACGCAGCGCATGATCGCCTGCCTGCAGGAGCGCTTTACGCAGGTGCGCATCGTGCGGACC
GCCGCCGAGTGCGCCGGTATCCGTATTGCTTATGCCGATCCCAGCCGCTTCGGTGTGGACCGCTTTTTGGCGCTGCTGGG
TGCGCGGGGCGACGCGCCGGTGCTGGTGGCCGGCGTGGGCACCGCACTGACCATCGACGTGCTGGGCGCCGATGGCCTGC
ATCATGGCGGCTGCATCGCCGCCTCGCCAACCACCATGCGCGAAGCGCTGCATGCGCGCGCGGTGCAGCTGCCGGCCAGC
GGCGGCGATTACGTCGAGCTGGCCATCGACACCGACGATGCCTTGACCTCCGGCTGCGACGGCGCGGCGGTGGCGCTGAT
CGAGCGCAGCTTGCAGCACGCGCAACGCAGCCTGGGCGCGCCGGTGCGGCTGCTCGTCCATGGTGGTGGCGCGCCGCCGC
TGCTACCGCTGCTGCCCGGTGCCACGTTCCGCGCCGCCTTGGTGCTGGACGGTCTGGCGACGTGGGCGACCGCTGCGGCA
TCCCCGTAG

Upstream 100 bases:

>100_bases
GTGGCGTTGCGCTCGGCCTGGCGGCCGACGGCGCGTTGCGGGTGCGACTGGGCGACACGGTGCGTCTGTTCCACTGCGGA
GAAGTGAGCGTGAGACCTGC

Downstream 100 bases:

>100_bases
AATCGGCGCATGTATGTCCGCGCGCTCATCGTCGTTTTGATCGTCCTCAATGCCGGGGTGGCGTTGTGGTGGGCCTTGCA
GCCACCGCCGGCACCGCCGC

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSEWLFDLGNSRFKYAPLHGNRAGQVQAWAHGAEAMDAAALAALPSGQIAHVASVAAPALTQRMIACLQERFTQVRIVRT
AAECAGIRIAYADPSRFGVDRFLALLGARGDAPVLVAGVGTALTIDVLGADGLHHGGCIAASPTTMREALHARAVQLPAS
GGDYVELAIDTDDALTSGCDGAAVALIERSLQHAQRSLGAPVRLLVHGGGAPPLLPLLPGATFRAALVLDGLATWATAAA
SP

Sequences:

>Translated_242_residues
MSEWLFDLGNSRFKYAPLHGNRAGQVQAWAHGAEAMDAAALAALPSGQIAHVASVAAPALTQRMIACLQERFTQVRIVRT
AAECAGIRIAYADPSRFGVDRFLALLGARGDAPVLVAGVGTALTIDVLGADGLHHGGCIAASPTTMREALHARAVQLPAS
GGDYVELAIDTDDALTSGCDGAAVALIERSLQHAQRSLGAPVRLLVHGGGAPPLLPLLPGATFRAALVLDGLATWATAAA
SP
>Mature_241_residues
SEWLFDLGNSRFKYAPLHGNRAGQVQAWAHGAEAMDAAALAALPSGQIAHVASVAAPALTQRMIACLQERFTQVRIVRTA
AECAGIRIAYADPSRFGVDRFLALLGARGDAPVLVAGVGTALTIDVLGADGLHHGGCIAASPTTMREALHARAVQLPASG
GDYVELAIDTDDALTSGCDGAAVALIERSLQHAQRSLGAPVRLLVHGGGAPPLLPLLPGATFRAALVLDGLATWATAAAS
P

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis [H]

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004619 [H]

Pfam domain/function: PF03309 Bvg_acc_factor [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 24806; Mature: 24674

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEWLFDLGNSRFKYAPLHGNRAGQVQAWAHGAEAMDAAALAALPSGQIAHVASVAAPAL
CCCCHHHCCCCCEEEECCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
TQRMIACLQERFTQVRIVRTAAECAGIRIAYADPSRFGVDRFLALLGARGDAPVLVAGVG
HHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHCHHHHHHHHCCCCCCCEEEEECC
TALTIDVLGADGLHHGGCIAASPTTMREALHARAVQLPASGGDYVELAIDTDDALTSGCD
CEEEEEEECCCCCCCCCEEECCCHHHHHHHHHHHEECCCCCCCEEEEEEECCHHHHCCCC
GAAVALIERSLQHAQRSLGAPVRLLVHGGGAPPLLPLLPGATFRAALVLDGLATWATAAA
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCC
SP
CC
>Mature Secondary Structure 
SEWLFDLGNSRFKYAPLHGNRAGQVQAWAHGAEAMDAAALAALPSGQIAHVASVAAPAL
CCCHHHCCCCCEEEECCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
TQRMIACLQERFTQVRIVRTAAECAGIRIAYADPSRFGVDRFLALLGARGDAPVLVAGVG
HHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHCHHHHHHHHCCCCCCCEEEEECC
TALTIDVLGADGLHHGGCIAASPTTMREALHARAVQLPASGGDYVELAIDTDDALTSGCD
CEEEEEEECCCCCCCCCEEECCCHHHHHHHHHHHEECCCCCCCEEEEEEECCHHHHCCCC
GAAVALIERSLQHAQRSLGAPVRLLVHGGGAPPLLPLLPGATFRAALVLDGLATWATAAA
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCC
SP
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]