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The map label for this gene is aroD

Identifier: 84489386

GI number: 84489386

Start: 669351

End: 670058

Strand: Direct

Name: aroD

Synonym: Msp_0577

Alternate gene names: 84489386

Gene position: 669351-670058 (Clockwise)

Preceding gene: 84489385

Following gene: 84489387

Centisome position: 37.87

GC content: 26.27

Gene sequence:

>708_bases
ATGATATTTTTTTTATTAGAAGGGGAGAGAGAAATTATTACTGAAATTTGTGGTTCAATTATTGAATCTAATGAAAAAGA
CATATTTAAAACATTAGATAAAGCAGTAGACTTGGATGTTAATTATATTGAATTAAGATTGGATGTTATTGAAAATATTA
CTTCGAAAAAAGCAACTTCTATCATTGAAAAAATAAGGAATGTTACAGATATTCCAATTATATTAACAAATAGAACGAAG
TATGAGGGAGGATATTTTCCATCTACAGAAGAGGATAGAATTAAAATATTGATGGATAATGCATCTCTTGTTGAATATAC
AGATATTGAATTATCTACCAATGAAAATCTTAGACAAGAAGTTATAGACAATGCTAATAGAACAATTATATCATATCATA
ATTTTGAAAAAACACCATCTTCTGAATATCTGGAGAATGTTGTAAATAGTGCATTGAATGTAGGAGATATAGCTAAAATT
GCTGTTAAACCATTAAATATTGAGGATACTTATGTTTTATTAAGATTACTTATGGAATATGATGATTTAATTGGTATTTC
TATGGATAAACTAGGTTCATATACAAGAATACTTGGACCAATATTAGGATCTCCTGTAACATATACAGCAATAACTGATG
AATCAGCTCCTGGCCAATTTGATGTTAAAACAACAAGAGATATTCTTAAAAAATTAAAAAATTATTAG

Upstream 100 bases:

>100_bases
AAAATTAACTAAAAAAATATTAGGTTATTAAATTGATAGTATTGTGAAATTTCTTAAATATTTTATGTTTTAAAAAATAG
ATTATTATTATAACTAAATT

Downstream 100 bases:

>100_bases
AATTGATTTATATGAATAAAAAGGATAGGCAGATTATTAAAACATTAAATAATCTTGGTGTAGATACAAGATATATTAGT
TTATATAATGAACATGTTTA

Product: hypothetical protein

Products: NA

Alternate protein names: 3-dehydroquinase; Type I DHQase

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MIFFLLEGEREIITEICGSIIESNEKDIFKTLDKAVDLDVNYIELRLDVIENITSKKATSIIEKIRNVTDIPIILTNRTK
YEGGYFPSTEEDRIKILMDNASLVEYTDIELSTNENLRQEVIDNANRTIISYHNFEKTPSSEYLENVVNSALNVGDIAKI
AVKPLNIEDTYVLLRLLMEYDDLIGISMDKLGSYTRILGPILGSPVTYTAITDESAPGQFDVKTTRDILKKLKNY

Sequences:

>Translated_235_residues
MIFFLLEGEREIITEICGSIIESNEKDIFKTLDKAVDLDVNYIELRLDVIENITSKKATSIIEKIRNVTDIPIILTNRTK
YEGGYFPSTEEDRIKILMDNASLVEYTDIELSTNENLRQEVIDNANRTIISYHNFEKTPSSEYLENVVNSALNVGDIAKI
AVKPLNIEDTYVLLRLLMEYDDLIGISMDKLGSYTRILGPILGSPVTYTAITDESAPGQFDVKTTRDILKKLKNY
>Mature_235_residues
MIFFLLEGEREIITEICGSIIESNEKDIFKTLDKAVDLDVNYIELRLDVIENITSKKATSIIEKIRNVTDIPIILTNRTK
YEGGYFPSTEEDRIKILMDNASLVEYTDIELSTNENLRQEVIDNANRTIISYHNFEKTPSSEYLENVVNSALNVGDIAKI
AVKPLNIEDTYVLLRLLMEYDDLIGISMDKLGSYTRILGPILGSPVTYTAITDESAPGQFDVKTTRDILKKLKNY

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; third step. [C]

COG id: COG0710

COG function: function code E; 3-dehydroquinate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I 3-dehydroquinase family

Homologues:

Organism=Escherichia coli, GI1787984, Length=233, Percent_Identity=28.3261802575107, Blast_Score=80, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320332, Length=191, Percent_Identity=34.0314136125654, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROD_METST (Q2NGS8)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_447618.1
- ProteinModelPortal:   Q2NGS8
- SMR:   Q2NGS8
- STRING:   Q2NGS8
- GeneID:   3854828
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_0577
- NMPDR:   fig|339860.6.peg.557
- eggNOG:   arNOG12575
- HOGENOM:   HBG732926
- OMA:   NHDFDKT
- PhylomeDB:   Q2NGS8
- ProtClustDB:   CLSK797932
- BioCyc:   MSTA339860:MSP_0577-MONOMER
- HAMAP:   MF_00214
- InterPro:   IPR013785
- InterPro:   IPR001381
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR01093

Pfam domain/function: PF01487 DHquinase_I

EC number: =4.2.1.10

Molecular weight: Translated: 26698; Mature: 26698

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: PS01028 DEHYDROQUINASE_I

Important sites: ACT_SITE 133-133 ACT_SITE 159-159

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFFLLEGEREIITEICGSIIESNEKDIFKTLDKAVDLDVNYIELRLDVIENITSKKATS
CEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IIEKIRNVTDIPIILTNRTKYEGGYFPSTEEDRIKILMDNASLVEYTDIELSTNENLRQE
HHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEEECCCCHHHHH
VIDNANRTIISYHNFEKTPSSEYLENVVNSALNVGDIAKIAVKPLNIEDTYVLLRLLMEY
HHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHEEECCCCCHHHHHHHHHHHH
DDLIGISMDKLGSYTRILGPILGSPVTYTAITDESAPGQFDVKTTRDILKKLKNY
HHHHCCCHHHHCHHHHHHHHHHCCCEEEEEEECCCCCCCEEHHHHHHHHHHHHCC
>Mature Secondary Structure
MIFFLLEGEREIITEICGSIIESNEKDIFKTLDKAVDLDVNYIELRLDVIENITSKKATS
CEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IIEKIRNVTDIPIILTNRTKYEGGYFPSTEEDRIKILMDNASLVEYTDIELSTNENLRQE
HHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEEECCCCHHHHH
VIDNANRTIISYHNFEKTPSSEYLENVVNSALNVGDIAKIAVKPLNIEDTYVLLRLLMEY
HHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHEEECCCCCHHHHHHHHHHHH
DDLIGISMDKLGSYTRILGPILGSPVTYTAITDESAPGQFDVKTTRDILKKLKNY
HHHHCCCHHHHCHHHHHHHHHHCCCEEEEEEECCCCCCCEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA